Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Slay the Day Tangerine Lemon Ingredients & Drug Interactions

by N by Nutrilite

Slay the Day Tangerine Lemon label
See full label image
Gummy Or Jelly Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Slay the Day Tangerine Lemon against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Slay the Day Tangerine Lemon is a dietary supplement by N by Nutrilite with 3 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 427 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are American Ginseng (root) extract, Vitamin B6, Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Slay the Day Tangerine Lemon by N by Nutrilite

Ask about any prescription or over-the-counter medication and we check it for interactions with Slay the Day Tangerine Lemon by N by Nutrilite — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Slay the Day Tangerine Lemon by N by Nutrilite

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients. Vitamin B6 is a B vitamin that helps your body use amino acids and make red blood cells and neurotransmitters.

Vitamin B12 is another B vitamin essential for nerve function, DNA, and red blood cell formation. American ginseng root extract is an herbal ingredient used traditionally to support energy and immune function.

The gummy also contains inactive ingredients like tapioca syrup, cane sugar, glycerin, agar, citric acid, lactic acid, and several others that give it texture, flavor, and shelf stability.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support concentration and mental focus.
  • We looked for evidence on: Attention, Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Cognitive impairment, Mental clarity, Concentration.
  • The closest evidence on file: Vitamin B12 is rated "Possibly Ineffective" for Cognitive impairment (Natural Medicines).
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Attention.
  • Also on file: Vitamin B6 is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

Vitamin B6 is effective for sideroblastic anemia (a type of anemia from iron that can't be used properly) and vitamin B6 deficiency itself. It's likely effective for high homocysteine (an amino acid linked to heart risk) and possibly effective for pregnancy-related nausea and vomiting.

Vitamin B12 is effective for vitamin B12 deficiency and Imerslund-Grasbeck disease (a rare absorption disorder), and likely effective for cyanide poisoning. It's possibly effective for canker sores and nerve pain after shingles.

American ginseng is possibly effective for upper respiratory infections, but the evidence for anemia of chronic disease and breast cancer is insufficient to rate.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 American Ginseng

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated in doses under 100 mg daily, though at high doses over time it can harm nerves (sensory neuropathy), especially above 1,000 mg daily or with very high cumulative doses. Common side effects at any dose include headache, nausea, abdominal pain, heartburn, and loss of appetite.

It's likely safe in pregnancy and lactation at normal amounts, though some pregnancy data rates it possibly unsafe—talk with your doctor about your specific dose. Vitamin B12 is very safe and has no established upper limit since your body clears excess in urine; it's likely safe in pregnancy and lactation.

Rare serious side effects include severe low potassium when B12 corrects certain types of anemia, and allergic reactions like rash. American ginseng is generally well tolerated short-term in healthy adults but long-term safety isn't well studied, and quality varies by brand.

The safety data advises against it in pregnancy and breastfeeding because of insufficient evidence.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 American Ginseng

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Vitamin B12, Vitamin B6, American Ginseng.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; Parkinson's medications.
  • For scale: 427 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you take warfarin or other blood thinners (ginseng may weaken them), seizure medications like phenobarbital or phenytoin (B6 might reduce their effect), blood pressure medications (B6 could lower it further), diabetes drugs (ginseng could lower blood sugar too much), older antidepressants called MAOIs, amiodarone (B6 may worsen sun sensitivity), metformin (it already lowers B12, so supplementing may mask a deficiency issue), or immune-suppressing drugs (ginseng might interfere). No interactions are documented for vitamin B12 beyond metformin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product makes sense if you're looking to fill vitamin B6 or B12 gaps, or exploring ginseng for immune support, and none of your medications are on the interaction list below. If you take any blood thinners, seizure drugs, blood pressure medications, diabetes drugs, older antidepressants, amiodarone, or metformin, you'll want to check with your doctor or pharmacist first—this product isn't necessarily off-limits, but the interactions need to be managed.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slay the Day Tangerine Lemon, straight from the product label.

Brand N by Nutrilite
Barcode (UPC) 850210008521
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 246404
Product type Botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slay the Day Tangerine Lemon by N by Nutrilite, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
850210008521
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates5 Gram(s)2%
Vitamin B62 mg120%
Vitamin B1250 mcg2080%
Added Sugars3 Gram(s)6%
Total Sugars3 Gram(s)--
American Ginseng (root) extract75 mg--

Other ingredients: Tapioca Syrup, Cane Sugar, Water, Glycerin, Agar, Natural flavors, Citric Acid, Lactic Acid, Paprika, Locust Bean Gum, Turmeric

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Try these focus gummies when you need a little help to get the job done.

Recycle Amway Promise

U got this.

Exclusively from Amway

Formula

Powered with ginseng, they help support concentration when you need it the most.

The Good Stuff Ginseng - an herb that helps support brain health.

Tangerine lemon with other natural flavors

Ginseng

Formulation

And don't worry! These are vegetarian friendly & free from all the nasties of artificial colors, flavors, and sweeteners.

And don't worry! These are vegetarian friendly & free from all the nasties of artificial colors, flavors, and sweeteners.

Free From: Peanuts, tree nuts, soy, eggs, high fructose corn syrup, shellfish, and crustacean. Caffeine free. GF Gluten free Dairy free

V Vegan

Focus

Product of Colombia.

Precautions

Keep out of the reach of children

If you have a medical condition, long-term focus disorder, chronic illness, are taking prescription drugs or are pregnant or nursing, please consult your healthcare professional prior to use.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Use Instructions: Adults: Take 2 gummies daily. Chew thoroughly before swallowing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Slay the Day Tangerine Lemon by N by Nutrilite label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Slay the Day Tangerine Lemon label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Slay the Day Tangerine Lemon by N by Nutrilite

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
50 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

American Ginseng (root) extract

Interacts with
217 drugs
75 mg per serving

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the...

American Ginseng (root) extract monograph & interactions

Other (inactive) ingredients: Tapioca Syrup, Cane Sugar, Water, Glycerin, Agar, Natural flavors, Citric Acid, Lactic Acid, Paprika, Locust Bean Gum, Turmeric. These complete the product’s ingredient list but are not active constituents.

Interaction report

Slay the Day Tangerine Lemon by N by Nutrilite Drug Interactions

Want to check YOUR meds against Slay the Day Tangerine Lemon?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
427Drugs
2 Major 420 Moderate 5 Minor

Ingredients driving the most interactions

American Ginseng (root) extract 217
Vitamin B6 210
Vitamin B12 20

Individual Drug Interactions

The ingredients in Slay the Day Tangerine Lemon interact with 427 drugs. Click any drug to see the details.

3 of the 3 ingredients in Slay the Day Tangerine Lemon interact with drugs. Each result below shows which ingredient is responsible. American Ginseng (root) extract Vitamin B6 Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Slay the Day Tangerine Lemon with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

American Ginseng (root) extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D
American Ginseng (root) extract full monograph & interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Slay the Day Tangerine Lemon, from the product label.

N by Nutrilite

See all N by Nutrilite products
Name
Amway Corp.
City
Ada
State
MI
ZipCode
49355
Phone Number
1-800-253-6500
Web Address
Amway.com
Pharmacist Counseling Corner

Slay the Day Tangerine Lemon by N by Nutrilite: Common Questions

Does Slay the Day Tangerine Lemon by N by Nutrilite interact with any medications?
Yes. Based on its ingredients, Slay the Day Tangerine Lemon has a known interaction with 427 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slay the Day Tangerine Lemon contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
The data gives mixed signals. Vitamin B6 is rated likely safe in pregnancy at normal amounts, though some data calls it possibly unsafe—and it's sometimes used for morning sickness under doctor supervision. Vitamin B12 is likely safe and is actually needed in pregnancy. American ginseng, though, is rated possibly unsafe in pregnancy because there isn't enough safety evidence. Talk with your doctor about whether this product is right for you during pregnancy, since the ginseng is the concern here.
Can I take this while breastfeeding?
Vitamin B6 and B12 are both considered likely safe at recommended amounts during breastfeeding. American ginseng, however, has too little safety data during breastfeeding, so the data advises against it. Speak with your doctor or pharmacist about whether the ginseng content makes this product suitable for you while nursing.
Is this product safe for long-term use?
Vitamins B6 and B12 are generally well tolerated long-term at normal doses, though very high B6 doses over time can damage nerves. American ginseng is generally well tolerated short-term in healthy adults, but long-term safety isn't well studied, and the quality varies between brands. For extended use, especially of the ginseng part, it's worth checking in with your doctor or pharmacist.
What does American ginseng actually do?
American ginseng is possibly effective for upper respiratory infections (colds, flu-like illnesses). It's traditionally used to support energy and immune function, but the evidence for other uses—like anemia or cancer—is not yet established in the data we have.
Can this cause headaches or nerve problems?
Yes. Headache is common with vitamin B6, and American ginseng can also cause headache. High doses of vitamin B6 over time can cause sensory neuropathy (nerve damage), especially at very high doses or cumulative amounts. At the doses in a gummy, this is less likely, but it's something to know about if you're combining this with other B6 sources.
Will this interfere with my diabetes medication?
American ginseng in this product may lower blood sugar, and if you're already on diabetes medication, the combination could drop your blood sugar too much. Check with your doctor or pharmacist before adding this to your routine if you take any diabetes drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slay the Day Tangerine Lemon is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slay the Day Tangerine Lemon label
Go deeper

The Full Monographs Behind Slay the Day Tangerine Lemon’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

American Ginseng

Interacts with 217 drugs

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly l...

Read the full American Ginseng monograph →
Sources

Sources & How We Checked

Slay the Day Tangerine Lemon's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 74 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
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See these in context on the Vitamin B12 monograph →

American Ginseng 12 references
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See these in context on the American Ginseng monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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