Interactions on record — worth a quick check against your medications. Based on 4 of 5 ingredients. Check your meds →
Dietary supplement

StemFlo Ingredients & Drug Interactions

by Stemtech

StemFlo label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking StemFlo against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

StemFlo is a dietary supplement by Stemtech with 5 active ingredients. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 1,510 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Grape pomace extract, Gotu Kola extract, Amla extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against StemFlo by Stemtech

Ask about any prescription or over-the-counter medication and we check it for interactions with StemFlo by Stemtech — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of StemFlo by Stemtech

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Proprietary Blend (Combination)” is a proprietary blend — the label gives one combined amount (1,525 mg) without saying how much of each component you get.
  • “Grape pomace extract” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

StemFlo contains 7 ingredients, most of them plant extracts. The active components are gotu kola extract (used in traditional medicine for circulation and skin healing), amla extract (also called Indian gooseberry, a rich source of vitamin C), lemon extract, black currant extract (which includes gamma-linolenic acid), cacao powder (which contains caffeine and compounds called flavonoids), turmeric extract (the source of curcumin), and a proprietary enzyme blend whose specific makeup isn't disclosed.

The product also includes vegetarian capsule material, cellulose, and silica as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support healthy circulation and blood flow.
  • We looked for evidence on: Atherosclerosis, Cardiovascular disease (CVD), Chronic venous insufficiency (CVI), Dyslipidemia, Vascular health, Endothelial function — and 1 related terms.
  • The strongest evidence on file: Gotu Kola is rated "Possibly Effective" for Venous insufficiency (Natural Medicines).
  • Also on file: Indian Gooseberry is rated "Possibly Effective" for Dyslipidemia.
  • Also on file: Cocoa is rated "Possibly Effective" for Cardiovascular disease (CVD).

The evidence for StemFlo's ingredients is mixed and incomplete. Gotu kola is rated possibly effective for venous insufficiency and burns, but possibly ineffective for radiation dermatitis and cognitive function — there's insufficient evidence for anxiety or Alzheimer's disease.

Amla extract shows possibly effective rating for GERD and dyslipidemia (high cholesterol), though evidence for baldness is insufficient. Lemon, black currant, and cacao lack sufficient evidence in our data for most uses they're traditionally associated with.

Cacao is rated possibly effective for cardiovascular disease. Turmeric extract is possibly effective for depression, high cholesterol, hay fever, and digestive discomfort.

Overall, the evidence base for this combination is not well established.

The evidence, ingredient by ingredient Gotu Kola Indian Gooseberry Lemon Grape

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in StemFlo are generally well tolerated in food amounts, but concentrated supplements raise more concern. Gotu kola is considered well tolerated short-term, though liver issues have been reported in rare cases; it's best avoided in pregnancy and during breastfeeding due to insufficient safety data.

Amla supplement safety is less well studied than its safety as a food; it should be avoided in pregnancy and breastfeeding. Lemon in food is safe, but medicinal amounts lack study.

Black currant berry is safe as a food, but concentrated supplements need caution — mild diarrhea has been reported. Cacao contains caffeine, which passes into breast milk; it's possibly safe in pregnancy but possibly unsafe at high doses.

Turmeric is likely safe in food and pregnancy at normal levels, but concentrated supplements carry a risk of liver damage — at least 70 reports of liver injury have been associated with turmeric supplements, though most resolved after stopping. The most common side effects across ingredients are mild gastrointestinal upset (nausea, heartburn, constipation) and, rarely, liver concerns.

Side effects, ingredient by ingredient Gotu Kola Indian Gooseberry Lemon Grape

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Lemon, Turmeric, Gotu Kola, Indian Gooseberry, Cocoa, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications; lithium.
  • For scale: 1,483 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking StemFlo, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel, apixaban, rivaroxaban — these carry Moderate bleeding-risk interactions), diabetes medications (risk of low blood sugar), CNS depressants like benzodiazepines or sleep aids (increased sedation), cancer drugs like tamoxifen or chemotherapy agents, tacrolimus (an immunosuppressant), antifungals like itraconazole, or any medication metabolized by your liver. Also mention if you take ephedrine, dipyridamole, quinolone antibiotics, beta-blockers, or antihypertensive drugs — cacao's caffeine content affects these.

No interactions are documented for the Proprietary Enzyme Blend, as we hold no data for it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

StemFlo may appeal to someone looking for traditional plant extracts for circulation, digestion, or general wellness, but it carries real medication interactions — especially with blood thinners, diabetes drugs, and certain cancer medications. If you take any prescription drug, especially for your heart, blood pressure, or liver, check with your doctor or pharmacist before starting this product.

Pregnant or breastfeeding persons should discuss it with their healthcare provider first, given limited safety data for several ingredients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about StemFlo, straight from the product label.

Brand Stemtech
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 24, 2017
DSLD ID 70289
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for StemFlo by Stemtech, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
IngredientAmount% DV
Proprietary Enzyme Blend0 NP--
Gotu Kola extract0 NP--
Proprietary Blend (Combination)1525 mg--
Amla extract0 NP--
Lemon extract0 NP--
Black Currant extract0 NP--
Grape pomace extract0 NP--
Cacao powder0 NP--
Turmeric extract0 NP--

Other ingredients: Vegetarian Capsule, Cellulose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

StemFlo contains a proprietary combination of active botanicals— packed with powerful antioxidants—and specially selected enzymes to support the smooth, easy flow of the body’s own stem cells, oxygen and nutrients to tissues and organs. This fast-acting, unique blend is scientifically formulated to maintain healthy fibrin levels, reduce oxidative stress, purify the blood of toxins, and support healthy inflammation levels.

General Statements

StemFlo is designed to work throughout the body to support healthy circulation and blood flow.

Product of USA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warnings: As with all dietary supplements, it is recommended that you consult your physician if you are pregnant, nursing, under treatment for any illness or taking anticoagulants or other medication.

Keep out of reach of children and pets.

Keep out of reach of children and pets.

Do not use if safety seal is broken.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules, once daily; 45 minutes before or 2 hours after a meal.

Formulation

Gluten Free. Contains no sugar, artificial colors, artificial flavors, dairy, yeast or preservatives.

Storage

Keep in a cool dry place. Do not refrigerate.

General

REV1-OCT15 Item Code: 1701

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

StemFlo by Stemtech label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

StemFlo label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in StemFlo by Stemtech

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend (Combination)

1525 mg per serving

Other (inactive) ingredients: Vegetarian Capsule, Cellulose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

StemFlo by Stemtech Drug Interactions

Want to check YOUR meds against StemFlo?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,510Drugs
1,457 Moderate 53 Minor

Ingredients driving the most interactions

Grape pomace extract 910
Gotu Kola extract 579
Amla extract 208
Lemon extract 1

Individual Drug Interactions

The ingredients in StemFlo interact with 1,510 drugs. Click any drug to see the details.

4 of the 5 ingredients in StemFlo interact with drugs. Each result below shows which ingredient is responsible. Grape pomace extract Gotu Kola extract Amla extract Lemon extract

Each ingredient & the kinds of drugs it affects

For each ingredient in StemFlo with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Grape pomace extract9 drug types · 910 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, grape extracts may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that grape extracts might decrease platelet aggregation.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Ingesting grape juice with cyclosporine can reduce cyclosporine absorption.
A small pharmacokinetic study in healthy young adults shows that intake of purple grape juice 200 mL along with cyclosporine can decrease the absorption of cyclosporine by up to 30% when compared with water. Separate doses of grape juice and cyclosporine by at least 2 hours to avoid this interaction.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, grape juice might reduce the levels of CYP1A2 substrates.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of CYP1A2.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, grape seed extract may increase the levels of CYP2D6 substrates.
In vitro evidence suggests that grape seed extract might inhibit CYP2D6 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, grape seed extract might increase the levels of CYP2E1 substrates.
In vitro and animal research suggests that grape seed proanthocyanidin extract inhibits CYP2E1 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

It is unclear if grape seed extract inhibits or induces CYP3A4; research is conflicting.
In vitro evidence suggests that grape seed extract might inhibit CYP3A4 enzymes. However, evidence from animal research shows that grape seed extract may induce CYP3A4 in the liver. So far, these interactions have not been reported in humans.

Likelihood Possible Evidence D
Midazolam (Versed)

Theoretically, long-term intake of grape seed extract might decrease the effects of midazolam.
Animal research shows that subchronic ingestions of grape seed extract can increase the elimination of intravenous midazolam by increasing hepatic CYP3A4 activity. Single doses of grape seed extract do not appear to affect midazolam elimination.

Likelihood Possible Evidence D
Phenacetin

Grape juice might decrease phenacetin absorption.
A small pharmacokinetic study in healthy adults shows that ingestion of 200 mL of grape juice decreases phenacetin plasma levels. This is thought to be due to induction of cytochrome P450 1A2 (CYP1A2).

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

It is unclear if grape juice or grape seed extract inhibits CYP2C9; research is conflicting.
In vitro evidence shows that grape seed extract or grape juice might inhibit CYP2C9 enzymes. However, a small pharmacokinetic study in healthy adults shows that drinking 8 ounces of grape juice once does not affect the clearance of flurbiprofen, a probe-drug for CYP2C9 metabolism. The effects of continued grape juice consumption are unclear.

Likelihood Unlikely Evidence D
Grape pomace extract full monograph & interactions

Gotu Kola extract2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
Gotu Kola extract full monograph & interactions

Amla extract4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
Amla extract full monograph & interactions

Lemon extract1 drug type · 1 drug

Itraconazole (Sporanox)

Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.

Likelihood Possible Evidence D
Lemon extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for StemFlo, from the product label.

Stemtech

See all Stemtech products
Name
Stemtech HealthSciences Corp.
City
Pembroke Pines
State
FL
ZipCode
33028
Phone Number
1-888-783-6832
Web Address
www.stemtech.com
Pharmacist Counseling Corner

StemFlo by Stemtech: Common Questions

Does StemFlo by Stemtech interact with any medications?
Yes. Based on its ingredients, StemFlo has a known interaction with 1,510 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
StemFlo contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product really work for better circulation or joint health?
The evidence is incomplete. Gotu kola is possibly effective for venous insufficiency (poor circulation in the legs), and turmeric is possibly effective for high cholesterol — but the evidence for other claims isn't established in our data. Talk to your doctor about whether any ingredient here matches what you need.
Can I take this if I'm on a blood thinner like warfarin or aspirin?
No — not without checking with your doctor first. Gotu kola, amla, black currant, and cacao all may increase bleeding risk when combined with blood thinners or aspirin. Your doctor may need to adjust your dose or monitor you more closely, or decide this product isn't right for you.
Is it safe to take this while pregnant or breastfeeding?
It depends on the ingredient. Gotu kola and amla should be avoided — there isn't enough safety data. Lemon and black currant in food amounts are probably okay, but medicinal supplements aren't well studied. Cacao's caffeine passes into breast milk. Talk with your doctor or pharmacist about whether this product is right for you right now.
What's the most common side effect I might notice?
Mild stomach upset — nausea, heartburn, or constipation — is most common, since several ingredients can affect digestion. Start with a lower dose and take it with food if you feel queasy. Serious side effects like liver damage are rare but have been reported with turmeric and gotu kola in concentrated forms.
I take diabetes medication. Is StemFlo safe for me?
Amla extract may lower blood sugar, which could mean your diabetes medication causes too much blood sugar drop. Your doctor may need to monitor your blood sugar more closely or adjust your dose. Check with them before starting.
Why does this product have so many different extracts in it?
The formula is designed to combine several plant-based ingredients traditionally used together for circulation, digestion, and overall wellness. However, that mix also means more potential interactions with medications and more ingredients to monitor for side effects — which is why it's important to check each of your current drugs before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

StemFlo label
Go deeper

The Full Monographs Behind StemFlo’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph → Herb & supplement monograph

Indian Gooseberry

Interacts with 208 drugs

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion. Early research is promising for some u...

Read the full Indian Gooseberry monograph → Herb & supplement monograph

Lemon

Interacts with 1 drug

Lemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it can support hydration and a healthy diet...

Read the full Lemon monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph →
Sources

Sources & How We Checked

StemFlo's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 287 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Lemon 2 references
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See these in context on the Cocoa monograph →

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See these in context on the Turmeric monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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