Strong Heart Tincture Ingredients & Drug Interactions
by Dr. Morse's Cellular Botanicals
What is this page for?
First and foremost: checking Strong Heart Tincture against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Strong Heart Tincture is a dietary supplement by Dr. Morse's Cellular Botanicals with 7 active ingredients. Its ingredients are commonly taken for thyroid support, iodine source, weight management.Based on those ingredients, 1,277 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Kelp, Parsley, Rosemary. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Strong Heart Tincture by Dr. Morse's Cellular Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Strong Heart Tincture by Dr. Morse's Cellular Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Strong Heart Tincture by Dr. Morse's Cellular Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Strong Heart Tincture contains seven active ingredients in a proprietary blend, delivered as a liquid. The blend includes kelp, astragalus, hawthorn, parsley, rosemary, motherwort, and bugleweed.
The inactive ingredients are alcohol and distilled water.
Does it work?
Not established
The effectiveness of these ingredients isn't well established in the data we hold. Rosemary is rated possibly effective for memory, but for the other ingredients—astragalus, hawthorn, parsley, motherwort, and bugleweed—the evidence is insufficient to rate their effectiveness for the conditions they're traditionally used for, including heart health, bleeding, anxiety, and thyroid function.
How safe is it?
Well-documented data
Astragalus and hawthorn are generally well tolerated short-term in healthy adults, though quality human safety data is limited for both. Parsley is safe in normal food amounts but concentrated extracts and seeds can carry serious risks at high doses, including anemia and kidney problems.
Rosemary is safe in culinary amounts, but concentrated extracts need caution. Motherwort may be tolerated short-term, but amounts over 3 grams can cause uterine bleeding.
Bugleweed may affect thyroid function and should only be used under healthcare provider guidance. For pregnancy: the facts advise against astragalus, hawthorn, parsley (medicinal amounts), motherwort, and bugleweed.
Rosemary in medicinal doses is possibly unsafe during pregnancy. For breastfeeding: astragalus, hawthorn, and parsley data are insufficient; motherwort should be avoided; bugleweed may reduce milk production.
Food amounts of rosemary are likely fine while breastfeeding, but medicinal doses lack safety data.
Meds to double-check
Major interaction found
Check your medications before starting if you take nitrates or erectile dysfunction drugs (Major risk with hawthorn), or immunosuppressants, blood thinners, diabetes medications, thyroid hormones, warfarin, aspirin, sedatives, or diuretics (Moderate risks across multiple ingredients). No interactions are documented for kelp, which we could not check.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
This product is not for everyone. If you take any blood pressure or heart medications, blood thinners, diabetes drugs, thyroid hormones, sedatives, or immunosuppressants, check with your pharmacist first.
The ingredients are traditionally used for heart support, but the evidence isn't strong. Anyone pregnant or breastfeeding should talk to their doctor or pharmacist before use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 7 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Strong Heart Tincture, straight from the product label.
| Brand | Dr. Morse's Cellular Botanicals |
|---|---|
| Net contents | 2 Ounce(s); 59 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 302984 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Strong Heart Tincture by Dr. Morse's Cellular Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1.6 mL | -- |
| Kelp | 0 NP | -- |
| Astragalus | 0 NP | -- |
| Hawthorn | 0 NP | -- |
| Parsley | 0 NP | -- |
| Rosemary | 0 NP | -- |
| Motherwort | 0 NP | -- |
| Bugleweed | 0 NP | -- |
Other ingredients: Alcohol, Water, Distilled
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Support cellular regeneration with our tissue specific formulas! Created with over 45 years of experience and the highest quality ingredients available. Experience health and vitality like never before! Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs
Made in the USA with global ingredients
Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs
Suggested/Recommended/Usage/Directions
Suggested Use by weight 25 lbs - 50 lbs... 2/3 dropperful 50 lbs - 75 lbs... 1 dropperful 75 lbs - 150 lbs... 2 dropperfuls Add to a little water or juice 3 times a day.
Precautions
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Formula
Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Strong Heart Tincture by Dr. Morse's Cellular Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Strong Heart Tincture by Dr. Morse's Cellular Botanicals
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.67 Dropperful(s) Dosage formLiquid Servings per container36 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Kelp
- › Astragalus
- › Hawthorn
- › Parsley
- › Rosemary
- › Motherwort
- › Bugleweed
Other (inactive) ingredients: Alcohol, Water, Distilled. These complete the product’s ingredient list but are not active constituents.
Strong Heart Tincture by Dr. Morse's Cellular Botanicals Drug Interactions
HelloPharmacist Interaction Report
Strong Heart Tincture by Dr.
Morse's Cellular Botanicals contains seven ingredients, and several of them interact with medications. The most serious interactions are with hawthorn, which carries Major-severity warnings for nitrates (used for chest pain) and phosphodiesterase-5 inhibitors (ED drugs like sildenafil)—both can cause dangerous drops in blood pressure when combined with hawthorn's vasodilatory effects.
Read the full breakdown — every affected drug type, severity by severity
Moderate interactions span multiple drug categories across the other ingredients. Astragalus may interfere with immunosuppressants, affect lithium levels, or increase the risk of low blood sugar (hypoglycemia) with diabetes medications.
Parsley and rosemary both theoretically increase bleeding risk with blood thinners (anticoagulants and antiplatelet drugs) and can raise the risk of low blood sugar with diabetes medications. Parsley may also interact with warfarin (Coumadin) due to its vitamin K content, and with certain sedatives and immunosuppressants.
Rosemary may add to the effects of aspirin and related salicylate drugs. Motherwort may increase sedation when taken with other CNS depressants.
Bugleweed may reduce the effects of thyroid hormones.
We could not check kelp for interactions, as we hold no data on it. Altogether, these interactions span 807 individual medications.
Run your specific prescriptions through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Strong Heart Tincture?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Strong Heart Tincture interact with 1,277 drugs. Click any drug to see the details.
7 of the 7 ingredients in Strong Heart Tincture interact with drugs. Each result below shows which ingredient is responsible. Kelp Parsley Rosemary Motherwort Astragalus Hawthorn Bugleweed
AvanafilStendra
How Avanafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Avanafil interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Finasteride, Tadalafil interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Macitentan, Tadalafil interactionKelpCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
Read the full Kelp + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorn + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Sildenafil interactionKelpCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
Read the full Kelp + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Sildenafil Citrate interactionKelpCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
Read the full Kelp + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Tadalafil interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
HawthornPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorn + Vardenafil interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Vardenafil interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
AstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
RosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Abciximab interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Abciximab interactionParsleyAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley + Abciximab interactionKelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Strong Heart Tincture — through 5 ingredients. Tap an ingredient for the detail:
RosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Abrocitinib interactionAstragalusImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus + Abrocitinib interactionParsleyAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley + Abrocitinib interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Abrocitinib interactionKelpAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Strong Heart Tincture — through 3 ingredients. Tap an ingredient for the detail:
AstragalusAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus + Acarbose interactionRosemaryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Rosemary + Acarbose interactionParsleyAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Parsley + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
HawthornBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorn + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
HawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acenocoumarol interactionParsleyAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Parsley + Acenocoumarol interactionRosemaryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Rosemary + Acenocoumarol interactionKelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Strong Heart Tincture — through 1 ingredient. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Aspirin interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Aspirin interactionHawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acetaminophen, Aspirin interactionKelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
HawthornAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorn + Acetaminophen, Aspirin, Caffeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Aspirin, Caffeine interactionParsleyCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Aspirin, Caffeine interactionKelpAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Strong Heart Tincture — through 2 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Butalbital interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Strong Heart Tincture — through 3 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Butalbital, Caffeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Caffeine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
ParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Butalbital, Caffeine, Codeine interactionMotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Caffeine, Codeine interactionKelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Acetaminophen, Butalbital, Caffeine, Codeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Codeine interactionParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Butalbital, Codeine interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Codeine interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Strong Heart Tincture — through 4 ingredients. Tap an ingredient for the detail:
MotherwortCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort + Acetaminophen, Butalbital, Codeine Phosphate interactionParsleyCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Read the full Parsley + Acetaminophen, Butalbital, Codeine Phosphate interactionKelpCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Acetaminophen, Butalbital, Codeine Phosphate interactionRosemaryCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Rosemary + Acetaminophen, Butalbital, Codeine Phosphate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Strong Heart Tincture with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Kelp
Amiodarone (Cordarone)
Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.
Thyroid Hormone
Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.
Anticoagulant/Antiplatelet Drugs
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.
Parsley
Anticoagulant/Antiplatelet Drugs
Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Animal research suggests that parsley has antiplatelet effects.
Antidiabetes Drugs
Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that parsley might decrease blood glucose. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Laboratory research suggests that parsley can inhibit CYP1A2.
Diuretic Drugs
Theoretically, parsley might enhance or interfere with the effects of diuretic drugs.
Animal research suggests that parsley seed extract increases urine elimination. Parsley leaf and root might also interfere with diuretic therapy due their purported aquaretic effects.
Pentobarbital (Nembutal)
Theoretically, parsley might increase the duration of pentobarbital effects.
Animal research suggests that parsley juice prolongs the action of pentobarbital, perhaps by decreasing cytochrome P450 levels. It is not known if this occurs in humans or if this applies to other barbiturates or sedatives.
Sirolimus (Rapamune)
Theoretically, large quantities of parsley might increase sirolimus levels.
In one case report, an adult female with a history of kidney transplant presented with elevated blood sirolimus levels, approximately 4-7 times greater than previous measures, after daily consumption of a juice containing approximately 30 grams of parsley for 7 days. Sirolimus levels returned to normal a week after the parsley juice was discontinued.
Warfarin (Coumadin)
Theoretically, large amounts of parsley leaf and root might decrease the effects of warfarin.
Parlsey contains vitamin K.
Aspirin
Theoretically, aspirin might increase the severity of allergic reactions to parsley.
In one case, severe urticaria and swelling were reported after taking aspirin with parsley in an individual with a known mild parsley allergy.
Rosemary
Anticoagulant/Antiplatelet Drugs
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.
Aspirin
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.
Choline Magnesium Trisalicylate (Trilisate)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.
Salsalate (Disalcid)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.
Motherwort
Cns Depressants
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Motherwort has been reported to cause CNS depression and sedation.
Astragalus
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Hawthorn
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Bugleweed
Thyroid Hormone
Theoretically, bugleweed may alter thyroid function.
Concomitant use of bugleweed may reduce the effects of thyroid hormones by blocking peripheral conversion of thyroxine (T4) to triiodothyronine (T3).
Brand information
Manufacturer and brand details for Strong Heart Tincture, from the product label.
Dr. Morse's Cellular Botanicals
See all Dr. Morse's Cellular Botanicals products- Name
- Western Botanicals FL, LLC
- City
- Spanish Fork
- State
- UT
- ZipCode
- 84660
- Web Address
- DMHHC.com
Strong Heart Tincture by Dr. Morse's Cellular Botanicals: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Strong Heart Tincture’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Fucus Vesiculosus
Interacts with 891 drugsFucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...
Read the full Fucus Vesiculosus monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph → Herb & supplement monographHawthorn
Interacts with 191 drugsHawthorn is a plant traditionally used for heart-related complaints, and some studies suggest it may modestly help symptoms of mild heart failure when added to standard care. However, the ev...
Read the full Hawthorn monograph → Herb & supplement monographParsley
Interacts with 443 drugsParsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...
Read the full Parsley monograph → Herb & supplement monographRosemary
Interacts with 372 drugsRosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory, mood, and hair growth, but the evidenc...
Read the full Rosemary monograph → Herb & supplement monographMotherwort
Interacts with 248 drugsMotherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but solid human evidence is very limited. It should be avo...
Read the full Motherwort monograph → Herb & supplement monographBugleweed
Interacts with 16 drugsBugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality human evidence is very limited. Because i...
Read the full Bugleweed monograph →Sources & How We Checked
Strong Heart Tincture's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 104 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fucus Vesiculosus 15 references
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
- Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
- Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
- Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
- Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
- Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
- Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
- Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
- Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
- Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
- Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
Parsley 21 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
- Eberhard P, Gall HM, Muller I, Moller R. Dramatic augmentation of a food allergy by acetylsalicylic acid. J Allergy Clin Immunol 2000;105:844 PubMed
- Tunali T, Yarat A, Yanardag R, et al. Effect of parsley (Petroselinum crispum) on the skin of STZ induced diabetic rats. Phytother Res 1999;13:138-41.. DOI
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
- Kreydiyyeh, S. I. and Usta, J. Diuretic effect and mechanism of action of parsley. J Ethnopharmacol 2002;79(3):353-357. PubMed
- Yanardag, R., Bolkent, S., Tabakoglu-Oguz, A., and Ozsoy-Sacan, O. Effects of Petroselinum crispum extract on pancreatic B cells and blood glucose of streptozotocin-induced diabetic rats. Biol Pharm Bull. 2003;26(8):1206-1210. PubMed
- Bolkent, S., Yanardag, R., Ozsoy-Sacan, O., and Karabulut-Bulan, O. Effects of parsley (Petroselinum crispum) on the liver of diabetic rats: a morphological and biochemical study. Phytother.Res 2004;18(12):996-999.
- Ozsoy-Sacan, O., Yanardag, R., Orak, H., Ozgey, Y., Yarat, A., and Tunali, T. Effects of parsley (Petroselinum crispum) extract versus glibornuride on the liver of streptozotocin-induced diabetic rats. J Ethnopharmacol 3-8-2006;104(1-2):175-181. PubMed
- Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem.Toxicol. 2006;44(9):147 PubMed
- Gadi, D., Bnouham, M., Aziz, M., Ziyyat, A., Legssyer, A., Legrand, C., Lafeve, F. F., and Mekhfi, H. Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats. J Ethnopharmacol 8-17-2009;125(1):170-174. PubMed
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Motherwort 6 references
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Bugleweed 4 references
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- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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