Interactions on record — worth a quick check against your medications. Based on 8 of 9 ingredients. Check your meds →
Dietary supplement

T-100 Ingredients & Drug Interactions

by AOR Advanced Orthomolecular Research Advanced

T-100 label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking T-100 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

T-100 is a dietary supplement by AOR Advanced Orthomolecular Research Advanced with 9 active ingredients. Its ingredients are commonly taken for mental focus and alertness, coping with stress, fatigue and sleep loss.Based on those ingredients, 2,177 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Thyroid extract, Bladderwrack (Fucus vesiculosus) extract, Thymus extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against T-100 by AOR Advanced Orthomolecular Research Advanced

Ask about any prescription or over-the-counter medication and we check it for interactions with T-100 by AOR Advanced Orthomolecular Research Advanced — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of T-100 by AOR Advanced Orthomolecular Research Advanced

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “ABgland Thyroid Glandular Extract Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

T-100 contains 9 ingredients, including L-tyrosine (an amino acid), adrenal extract, dulse (a seaweed high in iodine and potassium), thyroid glandular extract, thyroid extract, pituitary extract, thymus extract, spleen extract, Irish moss, and bladderwrack. The active ingredients here are thyroid extract—which contains real thyroid hormones—and L-tyrosine, which your body uses to make thyroid hormones and other brain chemicals.

The glandular extracts (thyroid, pituitary, thymus, spleen, and adrenal) are derived from animal tissues. The rest are botanical extracts and whole-plant materials.

The product also contains inactive ingredients like cellulose, gum acacia, stearic acid, magnesium stearate, and silicone dioxide, which serve as fillers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Support of a healthy thyroid.
  • We looked for evidence on: Hypothyroidism, Iodine deficiency, Thyroid function, Metabolic support.
  • The closest evidence on file: Fucus Vesiculosus is rated "Insufficient Reliable Evidence To Rate" for Hypothyroidism (Natural Medicines).
  • Also on file: Fucus Vesiculosus is rated "Insufficient Reliable Evidence To Rate" for Iodine deficiency.
  • Also on file: Thyroid Extract is rated "Insufficient Reliable Evidence To Rate" for Hypothyroidism.

The evidence for most of these ingredients is limited or unestablished. L-tyrosine is effective for phenylketonuria (PKU) and possibly effective for cognitive function and memory, but only possibly ineffective for athletic performance.

Thymus extract is possibly effective for dilated cardiomyopathy (a heart condition) and respiratory tract infections. Thyroid extract, adrenal extract, dulse, pituitary extract, spleen extract, Irish moss, and bladderwrack all have insufficient evidence in our data to rate their effectiveness for the conditions they're used for.

If you're considering this product for a specific health goal, talk with your pharmacist about what the evidence actually supports.

The evidence, ingredient by ingredient Tyrosine Dulse Adrenal Extract Thyroid Extract Thymus Extract Spleen Extract Sea Moss Fucus Vesiculosus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-tyrosine is generally well tolerated in healthy adults, though common side effects at higher doses include fatigue, headache, heartburn, and nausea. The glandular extracts (adrenal, thyroid, pituitary, thymus, and spleen) all carry safety concerns because they're derived from raw animal tissues gathered from slaughterhouses—there's a risk of contamination, including concern about bovine spongiform encephalopathy (BSE, a serious prion disease) if sourced from affected countries.

Thyroid extract poses an extra risk because it contains active hormones in uncontrolled amounts; taking it without medical supervision can cause abnormally high thyroid hormone levels and, in rare cases, thyroid storm. Dulse is generally safe as food but as a concentrated supplement carries unpredictable iodine and potassium levels with limited safety data.

Side effects, ingredient by ingredient Tyrosine Dulse Adrenal Extract Thyroid Extract Thymus Extract Spleen Extract Sea Moss Fucus Vesiculosus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 8 matched ingredients can interact with medications — Fucus Vesiculosus, Thymus Extract, Tyrosine, Thyroid Extract, Dulse, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 2,178 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take levothyroxine (Synthroid, others), thyroid hormones, or antithyroid drugs—the thyroid extract and L-tyrosine in this formula can change how they work. If you're on digoxin (a heart medication), levodopa (Parkinson's disease), amiodarone (heart rhythm), ACE inhibitors, ARBs, or potassium-sparing diuretics, this product's dulse and L-tyrosine content needs review.

If you take immunosuppressants, the thymus extract poses a small contamination risk. Run your exact medications through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines amino acids with raw animal tissue extracts and seaweed, creating a profile that's not suitable for people on thyroid medications, heart medications (especially digoxin or amiodarone), or blood pressure drugs that affect potassium. If you're not on any of those medications and you're interested in the ingredients for cognitive or immune support, talk with your pharmacist first—the glandular extracts carry contamination risks that aren't well controlled in most OTC products, and the thyroid component really needs medical oversight.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about T-100, straight from the product label.

Brand AOR Advanced Orthomolecular Research Advanced
Barcode (UPC) 624917080223
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 214870
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Male (18-50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for T-100 by AOR Advanced Orthomolecular Research Advanced, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
624917080223
IngredientAmount% DV
L-Tyrosine60 mg, 30 mg--
Adrenal extract100 mg, 50 mg--
Dulse (Rhodymenia palmata) extract800 mg, 400 mg--
ABgland Thyroid Glandular Extract Blend0 NP, 0 NP--
Thyroid extract200 mg, 100 mg--
Pituitary extract30 mg, 15 mg--
Thymus extract10 mg, 5 mg--
Spleen extract10 mg, 5 mg--
Irish Moss (Chondrus crispus) wholeplant extract80 mg, 40 mg--
Bladderwrack (Fucus vesiculosus) extract30 mg, 15 mg--

Other ingredients: Microcrystalline Cellulose, Gum Acacia, Stearic Acid, Magnesium Stearate, Hypermellose, Silicon Dioxide, Dicalcium Phosphate, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

GMP Manufacturing Quality assured Independent testing

Discussion: T-100 is a glandular formulation for the support of a healthy thyroid.

Non-GMO Gluten free

AOR guarantees that all ingredients have been declared on the label.

Free of bovine spongiform encephalopathy (BSE/ “mad cow disease”). Made without wheat, gluten, corn, nuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish, or any ingredients of porcine origin.

Precautions

Do not use if safety seal is broken

Warning: Do not use if you are pregnant or lactating. Consult your physician before use if you have a medical condition, or if you’re taking any medication.

Keep out of reach of children.

Caution: May cause gastrointestinal disturbances such as epigastric burning sensation and nausea. Consult a health care practitioner prior to use if you are following a low protein diet. Discontinue use if rash develops.

To report a serious adverse event or obtain product information, call 1-866-215-0450

Storage

Store tightly sealed in a cool, dry place

Suggested/Recommended/Usage/Directions

Directions: Take 1 tablet 1-2 times per day with food, or as directed by a qualified health care practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Thyroid glandular and nutrients

FDA Statement of Identity

Dietary Supplement

General Statements

Product of USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

T-100 by AOR Advanced Orthomolecular Research Advanced label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

T-100 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in T-100 by AOR Advanced Orthomolecular Research Advanced

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Tyrosine

Interacts with
21 drugs
60 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

Dulse (Rhodymenia palmata) extract

Interacts with
85 drugs
800 mg per serving

Dulse is a red seaweed eaten as a food in many coastal cultures and is a natural source of iodine, potassium, protein, and antioxidant compounds. As a...

Dulse (Rhodymenia palmata) extract monograph & interactions

ABgland Thyroid Glandular Extract Blend

0 NP per serving

Irish Moss (Chondrus crispus) wholeplant extract

Interacts with
22 drugs
80 mg per serving

Sea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human...

Irish Moss (Chondrus crispus) wholeplant extract monograph & interactions

Bladderwrack (Fucus vesiculosus) extract

Interacts with
891 drugs
30 mg per serving

Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is l...

Bladderwrack (Fucus vesiculosus) extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Gum Acacia, Stearic Acid, Magnesium Stearate, Hypermellose, Silicon Dioxide, Dicalcium Phosphate, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

T-100 by AOR Advanced Orthomolecular Research Advanced Drug Interactions

Want to check YOUR meds against T-100?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,177Drugs
150 Moderate 2,027 Minor

Ingredients driving the most interactions

Thyroid extract 2,022
Bladderwrack (Fucus vesiculosus) extract 891
Thymus extract 121
Dulse (Rhodymenia palmata) extract 85
Irish Moss (Chondrus crispus) wholeplant extract 22

Individual Drug Interactions

The ingredients in T-100 interact with 2,177 drugs. Click any drug to see the details.

6 of the 9 ingredients in T-100 interact with drugs. Each result below shows which ingredient is responsible. Thyroid extract Bladderwrack (Fucus vesiculosus) extract Thymus extract Dulse (Rhodymenia palmata) extract Irish Moss (Chondrus crispus) wholeplant extract L-Tyrosine

Each ingredient & the kinds of drugs it affects

For each ingredient in T-100 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Thyroid extract2 drug types · 2,022 drugs

Levothyroxine (Synthroid, Others)

Theoretically, thyroid extract might increase the effects and adverse effects of levothyroxine.
Thyroid extract contains triiodothyronine (T3) and thyroxine (T4). Taking thyroid extract increases blood levels of T3 and T4, in some cases to abnormally high levels.

Likelihood Possible Evidence D
Oral Drugs

Food and medications can interfere with thyroid hormone absorption. Some foods, particularly those high in fiber or containing certain minerals like calcium or iron, can bind to thyroid hormones and reduce their absorption in the digestive tract. Additionally, taking thyroid medications with certain drugs, like antacids or calcium supplements, can hinder the effectiveness of the thyroid medication, necessitating adjustments in dosage or timing. Prescription thyroid medications, such as Synthroid, are recommended to be taken on an empty stomach, at least 30 minutes before food and other medications, for optimal absorption.

Likelihood Likely Evidence A
Thyroid extract full monograph & interactions

Bladderwrack (Fucus vesiculosus) extract9 drug types · 891 drugs

Amiodarone (Cordarone)

Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Possible Evidence D
Lithium

Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.

Likelihood Unlikely Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Bladderwrack (Fucus vesiculosus) extract full monograph & interactions

Thymus extract1 drug type · 121 drugs

Immunosuppressants

Theoretically, patients taking immunosuppressants may be at an increased risk of infection from contaminated thymus extract.
Thymus extract is derived from raw bovine thymus glands and is at risk for contamination. Tell patients to avoid thymus extract products unless these products are certified as pathogen-free.

Likelihood Possible Evidence D
Thymus extract full monograph & interactions

Dulse (Rhodymenia palmata) extract7 drug types · 85 drugs

Amiodarine (Cordarone)

Theoretically, combining dulse with amiodarone might cause excessively high iodine levels.
Dulse is rich in iodine, and amiodarone contains 37.3% iodine and can increase iodine levels.

Likelihood Possible Evidence D
Antithyroid Drugs

Theoretically, due to its iodine content, dulse might alter the effects of antithyroid drugs.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, dulse might increase the risk of hyperkalemia when taken with digoxin.
Dulse is rich in potassium, and digoxin can increase potassium levels in the blood. This interaction has not been demonstrated in humans.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, due to its iodine content, dulse might alter the effects of thyroid hormone.
Dulse is rich in iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Although dulse has been associated with a statistically significant increase in thyroid stimulating hormone (TSH) levels in clinical research, clinically significant increases have not been documented.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, dulse might increase the risk of hyperkalemia when taken with ACEIs.
Dulse is rich in potassium. ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide larger amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of ACE. However, these effects have not been demonstrated in humans.

Likelihood Possible Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, dulse might increase the risk of hyperkalemia when taken with ARBs.
Dulse is rich in potassium. ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels. However, using these drugs while consuming dulse in quantities that provide higher amounts of potassium daily might increase the risk of hyperkalemia. Additionally, in vitro research suggests that dulse protein hydrolysates inhibit the activity of angiotensin converting enzyme (ACE). However, these effects have not been demonstrated in humans.

Likelihood Possible Evidence D
Potassium-Sparing Diuretics

Theoretically, dulse might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dulse is rich in potassium, and potassium-sparing diuretics can increase potassium levels in the blood. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Dulse (Rhodymenia palmata) extract full monograph & interactions

Irish Moss (Chondrus crispus) wholeplant extract3 drug types · 22 drugs

Amiodarone (Cordarone)

Theoretically, combining sea moss with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with sea moss, which contains approximately 4-7 mcg of iodine per gram, might increase the risk of adverse effects from iodine, including altered thyroid function.

Likelihood Possible Evidence D
Antithyroid Drugs

Due to its iodine content, sea moss might alter the effects of antithyroid drugs.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of antithyroid drugs.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, sea moss might alter the effects of thyroid hormone.
Sea moss contains approximately 4-7 mcg of iodine per gram. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking sea moss could theoretically alter the effects of thyroid hormone.

Likelihood Possible Evidence D
Irish Moss (Chondrus crispus) wholeplant extract full monograph & interactions

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
L-Tyrosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for T-100, from the product label.

AOR Advanced Orthomolecular Research Advanced

See all AOR Advanced Orthomolecular Research Advanced products
Name
AOR Inc.
Street Address
30 Industrial West
City
Clifton
State
NJ
ZipCode
07012
Phone Number
1-866-215-0450
Pharmacist Counseling Corner

T-100 by AOR Advanced Orthomolecular Research Advanced: Common Questions

Does T-100 by AOR Advanced Orthomolecular Research Advanced interact with any medications?
Yes. Based on its ingredients, T-100 has a known interaction with 2,177 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
T-100 contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's in this formula, and what's it supposed to do?
T-100 combines L-tyrosine, thyroid and pituitary glandular extracts, and several seaweed and organ-tissue extracts. The thyroid extract contains active hormones, and L-tyrosine is a building block for thyroid hormones and brain chemicals. It's marketed for thyroid and energy support, but the evidence for most ingredients is limited or unestablished in our data.
Is L-tyrosine effective for memory and focus?
L-tyrosine is possibly effective for cognitive function and memory according to the data we hold, though the evidence isn't rock-solid. It's a precursor to dopamine and other brain chemicals, so the theory makes sense—but talk with your pharmacist about whether this product is the right fit for your goals.
Can I take this if I'm on thyroid medication?
You shouldn't without checking with your doctor or pharmacist first. This product contains thyroid extract (real thyroid hormones) and L-tyrosine, both of which can interfere with levothyroxine and other thyroid drugs. Taking them together can raise your hormone levels too high and cause serious side effects.
What are the glandular extracts, and are they safe?
They're tissues from animal organs—adrenal, pituitary, thymus, and spleen—taken from slaughterhouses. While used traditionally, they carry a small risk of contamination from diseased tissue, and the evidence for benefit is weak or absent. Most experts recommend avoiding them unless you know the manufacturer has certified the product as pathogen-free.
What side effects might I get from L-tyrosine?
At normal doses, L-tyrosine is generally well tolerated. At higher doses, fatigue, headache, heartburn, and nausea are reported. If you're taking multiple supplements or medications that affect neurotransmitters, talk with your pharmacist about the dose and any combined risk.
Is it safe to take this while pregnant or breastfeeding?
No—the thyroid extract should be avoided in both pregnancy and breastfeeding because unregulated thyroid hormones can harm the developing baby or pass into breast milk. The glandular extracts also lack safety data and should be avoided. Talk with your doctor about any support you're considering during these times.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if T-100 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

T-100 label
Go deeper

The Full Monographs Behind T-100’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tyrosine

Interacts with 21 drugs

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss,...

Read the full Tyrosine monograph → Herb & supplement monograph

Dulse

Interacts with 85 drugs

Dulse is a red seaweed eaten as a food in many coastal cultures and is a natural source of iodine, potassium, protein, and antioxidant compounds. As a food it is generally considered safe fo...

Read the full Dulse monograph → Herb & supplement monograph

Adrenal Extract

Adrenal extract is a glandular supplement made from the adrenal glands of animals, and it is marketed mainly for fatigue and so-called "adrenal fatigue." There is no good scientific evidence...

Read the full Adrenal Extract monograph → Herb & supplement monograph

Thyroid Extract

Interacts with 2,022 drugs

Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in over-the-counter products are not standardized and...

Read the full Thyroid Extract monograph → Herb & supplement monograph

Thymus Extract

Interacts with 121 drugs

Thymus extract is a glandular product made from the thymus tissue of animals, and it is promoted mainly for immune support. The evidence is mostly limited, preliminary, or from older studies...

Read the full Thymus Extract monograph → Herb & supplement monograph

Spleen Extract

Spleen extract is a glandular supplement made from the spleen tissue of animals such as cows or pigs, promoted mainly for immune support. There is very little reliable human research to show...

Read the full Spleen Extract monograph → Herb & supplement monograph

Sea Moss

Interacts with 22 drugs

Sea moss is a type of red seaweed that is naturally rich in iodine and several minerals, and it is popular as a 'whole-food' supplement. Strong human evidence for most of its health claims i...

Read the full Sea Moss monograph → Herb & supplement monograph

Fucus Vesiculosus

Interacts with 891 drugs

Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...

Read the full Fucus Vesiculosus monograph →
Sources

Sources & How We Checked

T-100's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 38 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Adrenal Extract 2 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Nationwide alert on hallmark labs injectable adrenal cortex extract. FDA. Available at: www.fda.gov/bbs/topics/NEWS/NEW00539.html

See these in context on the Adrenal Extract monograph →

Dulse 5 references
  1. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  2. Allsopp P, Crowe W, Bahar B, et al. The effect of consuming Palmaria palmata-enriched bread on inflammatory markers, antioxidant status, lipid profile and thyroid function in a randomised placebo-controlled intervention trial in healthy adults. Eur J Nutr PubMed
  3. McGrath BM, Harmon JP, Bishop G. Palmaria palmata (Dulse) as an unusual maritime aetiology of hyperkalemia in a patient with chronic renal failure: a case report. J Med Case Rep. 2010;4:301. PubMed
  4. Furuta T, Miyabe Y, Yasui H, Kinoshita Y, Kishimura H. Angiotensin I converting enzyme inhibitory peptides derived from phycobiliproteins of dulse Palmaria palmata. Mar Drugs. 2016;14(2):32. PubMed
  5. Takase T, Nakamura A, Miyoshi H, et al. Effects of Palmaria palmata on lipid metabolism and glycemic control in participants with hypercholesterolemia in a randomized double-blind placebo-controlled trial. Phytother Res. 2020.

See these in context on the Dulse monograph →

Thyroid Extract 6 references
  1. Benvenga, S., Trimarchi, F., Barbera, C., Costante, G., Morabito, S., Barberio, G., and Consolo, F. Circulating immunoglobulin E (IgE) antibodies to L-thyroxine in a euthyroid patient with multinodular goiter and allergic rhinitis. J Endocrinol Invest 198 PubMed
  2. Gerard, P., Malvaux, P., and De Visscher, M. Accidental poisoning with thyroid extract treated by exchange transfusion. Arch Dis Child 1972;47(256):981-982. PubMed
  3. Tofahrn, J. and Hundeiker, M. [Nevus eruption following thyroidin with spontaneous involution]. Z Hautkr 1976;51(15):617-620.
  4. Rees-Jones RW, Larsen PR. Triiodothyronine and thyroxine content of desiccated thyroid tablets. Metabolism 1977;26(11):1213-1218. PubMed
  5. Jackson IM, Cobb WE. Why does anyone still use desiccated thyroid USP? Am J Med 1978;64(2):284-8. PubMed
  6. Jha S, Waghdhare S, Reddi R, Bhattacharya P. Thyroid storm due to inappropriate administration of a compounded thyroid hormone preparation successfully treated with plasmapheresis. Thyroid. 2012;22(12):1283-6. PubMed

See these in context on the Thyroid Extract monograph →

Thymus Extract 2 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Nationwide alert on hallmark labs injectable adrenal cortex extract. FDA. Available at: www.fda.gov/bbs/topics/NEWS/NEW00539.html

See these in context on the Thymus Extract monograph →

Spleen Extract 1 reference
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.

See these in context on the Spleen Extract monograph →

Sea Moss 3 references
  1. Darias-Rosales J, Rubio C, Gutiérrez ÁJ, Paz S, Hardisson A. Risk assessment of iodine intake from the consumption of red seaweeds (Palmaria palmata and Chondrus crispus). Environ Sci Pollut Res Int 2020;27(36):45737-45741. PubMed
  2. U.S. Department of Agriculture (USDA). Agricultural Research Service. FoodData Central. Seaweed, irishmoss, raw. April 2019. Available at: https://fdc.nal.usda.gov/fdc-app.html#/food-details/168456/nutrients. Accessed Aug. 30, 2022.
  3. Palmieri B, Vadalà M, Laurino C. Clinical effects of overwintered-stressed Chondrus Crispus and non-overwintered-stressed Chondrus crispus dietary supplementations. Asian J Med Sci. 2018; 9(6): 7-13. DOI

See these in context on the Sea Moss monograph →

Fucus Vesiculosus 15 references
  1. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
  4. Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
  5. Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
  6. Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
  7. Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
  8. Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
  9. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  10. Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
  11. Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
  12. Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
  13. Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
  14. Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
  15. Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.

See these in context on the Fucus Vesiculosus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team