Transfer Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Transfer against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Transfer is a dietary supplement by Cutler Nutrition with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, high cholesterol, indigestion and gas.Based on those ingredients, 1,160 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Dihydroberberine, Ceylon Cinnamon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Transfer by Cutler Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Transfer by Cutler Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Transfer by Cutler Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Transfer contains 2 active ingredients: Ceylon cinnamon and dihydroberberine. Ceylon cinnamon is the spice from the cinnamon tree bark, used here in supplement strength rather than as a food spice.
Dihydroberberine is a modified form of berberine, an alkaloid compound from plants like goldenseal and barberry that your body may absorb more easily than standard berberine. The capsule itself is made from vegetable cellulose with silicon dioxide and magnesium stearate as inactive ingredients — these are common binders and flow agents that help manufacture and deliver the capsule.
Does it work?
Moderate evidence
The evidence for Transfer's ingredients is mixed. For Ceylon cinnamon, the data suggests it's possibly ineffective for obesity and diabetes — the two conditions where it's most often promoted.
The evidence is insufficient to rate it for hay fever, COPD, and common cold. For dihydroberberine (berberine), the data shows it's possibly effective for high cholesterol (hyperlipidemia), polycystic ovary syndrome (PCOS), H. pylori infection, high blood pressure, and diabetes.
That said, the effectiveness of dihydroberberine specifically — rather than standard berberine — is not separately established in our data, so results may differ.
How safe is it?
Well-documented data
Ceylon cinnamon is generally well tolerated when you eat it as a spice, but supplement doses are less studied. Most users don't report problems, though some experience bloating, indigestion, and nausea.
There is one reported case of bleeding (hemorrhage) in a patient taking large amounts of Ceylon cinnamon daily for months after surgery, though this is rare. Some people develop an itchy rash or skin irritation, especially if they're sensitive to cinnamon.
Berberine is generally well tolerated short-term but causes digestive side effects — abdominal pain, constipation, diarrhea, and nausea — in a number of trial participants. It can also cause dizziness, drowsiness, fatigue, and headache.
Do not use Transfer during pregnancy or while breastfeeding: berberine may cross the placenta and has been linked to harm in newborns, and it passes into breast milk.
Meds to double-check
Major interaction found
Before taking Transfer, double-check these medication types with your pharmacist: cyclosporine (Major severity); blood pressure medications, diabetes drugs, blood thinners, sedating medications, and any drugs broken down by your liver — especially those metabolized by CYP3A4, CYP2D6, or CYP2C9 enzymes (all Moderate severity).
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Transfer may appeal to someone looking to support blood sugar or cholesterol with herbal ingredients, but the evidence for Ceylon cinnamon's effectiveness is weak, and berberine's benefit is modest. The major concern is the number of medications it can interact with — particularly cyclosporine, blood pressure drugs, diabetes medications, and blood thinners.
Check your exact medications with the search tool before starting, and talk to your pharmacist if you're on any prescription drugs or if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Transfer, straight from the product label.
| Brand | Cutler Nutrition |
|---|---|
| Barcode (UPC) | 850002859539 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 275708 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Transfer by Cutler Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Ceylon Cinnamon | 750 mg | -- |
| Dihydroberberine | 170 mg | -- |
Other ingredients: Vegetable Cellulose, Silicon Dioxide, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Transfer /trans'fer, 'transfer/: Move from one place to another.
X002TC9ATF
Pro approved
Formulation
By optimizing healthy blood sugar levels, Transfer helps create a favorable environment for the body to partition nutrients to preferably muscle cells - not fat.
Vegan friendly
Extra strength formula
Manufactured in the USA using domestic & imported ingredients
Weight management Healthy blood sugar levels Healthy ampk levels
Formula
With a calculated blend of ceylon cinnamon the patented form of dihydroberine, GlucoVantage, Transfer has the tools to help any athlete reach their ideal physique.
Keto friendly
Dihydroberberine + cinnamon matrix
Featuring: Gluco Vantage
Precautions
Warning: Not intended for persons under the age of 18. Do not exceed the recommended dose. Read the entire label and consult your physical prior to use.
Avoid if you are pregnant, nursing, allergic, or have a medical condition, or are taking any medication such as blood glucose lowering medication, MAOI inhibitors, antidepressants, aspirin, nonsteroidal anti inflammatory drugs.
Consult your physician prior to use if you have a medical condition, including but not limited to, heart, liver, kidney, or thyroid disease, diabetes, high blood pressure, or cardiac arrhythmia. Do not use if product has been opened or tampered with in any other way.
Keep out of reach of children.
Allergen warning: Made in a facility that processes soy, egg, peanuts, tree nuts, fish, shellfish, and wheat products.
Storage
Store in a cool, dry place.
Seals/Symbols
GMP Quality
Brand IP Statement(s)
Cutler Nutrition Train Like a Pro
GlucoVantage is a registered trademark of NNB Nutrition
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommended use: As a dietary supplement, take one (1) capsule twice daily with meals. It is not recommended to take transfer on an empty stomach. Do not exceed more than 3 capsules in a 24-hour period.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Transfer by Cutler Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Transfer by Cutler Nutrition
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegetarian Capsules Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Ceylon Cinnamon
Interacts with258 drugs
Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evid...
Ceylon Cinnamon monograph & interactionsDihydroberberine
Interacts with1,160 drugs
Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research vari...
Dihydroberberine monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Transfer by Cutler Nutrition Drug Interactions
HelloPharmacist Interaction Report
Transfer by Cutler Nutrition contains Ceylon cinnamon and dihydroberberine (a form of berberine), and both ingredients have documented interactions with medications.
The most serious concern is dihydroberberine with cyclosporine (an immunosuppressant drug used after organ transplants and for certain autoimmune conditions). Berberine can slow how your body clears cyclosporine, raising its levels and the risk of side effects — this is a Major interaction.
Read the full breakdown — every affected drug type, severity by severity
Berberine also interacts with several other drug types at Moderate severity: blood pressure medications (antihypertensive drugs), sedating drugs (CNS depressants), diabetes medications, blood thinners (anticoagulants and antiplatelet drugs), and certain drugs your liver breaks down using enzymes called CYP3A4, CYP2D6, and CYP2C9. Ceylon cinnamon adds Moderate interactions with blood pressure and diabetes medications.
Altogether, these interactions span 1,148 individual medications.
Ceylon cinnamon is generally well tolerated when taken orally, though bloating, indigestion, and nausea occur in some users. Berberine causes digestive upset — abdominal pain, constipation, diarrhea, and nausea — in a number of people, and can also cause dizziness, drowsiness, and headache.
Before you start Transfer, run your exact medications through the search tool below. If you take cyclosporine, blood pressure or diabetes drugs, blood thinners, sedating medications, or any drug metabolized by the liver enzymes listed above, check with your pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Transfer?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Transfer interact with 1,160 drugs. Click any drug to see the details.
2 of the 2 ingredients in Transfer interact with drugs. Each result below shows which ingredient is responsible. Dihydroberberine Ceylon Cinnamon
AcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineCns Depressants, Antihypertensive Drugs +1 Moderate
Interaction Summary
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Dihydroberberine + Acetazolamide interactionCeylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
Ceylon CinnamonAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon + Acetohexamide interactionDihydroberberineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Dihydroberberine + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Dihydroberberine + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
Read the full Dihydroberberine + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Read the full Dihydroberberine + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Dihydroberberine + Albiglutide interactionCeylon CinnamonAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Dihydroberberine + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Aliskiren interactionCeylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Dihydroberberine + Alogliptin interactionCeylon CinnamonAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
Ceylon CinnamonAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon + Alogliptin, Metformin interactionDihydroberberineAntidiabetes Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Dihydroberberine + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
Ceylon CinnamonAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon + Alogliptin, Pioglitazone interactionDihydroberberineAntidiabetes Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Dihydroberberine + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Dihydroberberine + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Dihydroberberine + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Dihydroberberine + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might have additive effects with antihypertensive drugs.
Read the full Dihydroberberine + Ambrisentan interactionCeylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
Ceylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Amiloride interactionDihydroberberineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, berberine might have additive effects with antihypertensive drugs.
Read the full Dihydroberberine + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, berberine might have additive effects with antihypertensive drugs.
Read the full Dihydroberberine + Amiloride, Hydrochlorothiazide interactionCeylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Amiloride, Hydrochlorothiazide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCns Depressants Moderate
Interaction Summary
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Dihydroberberine + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCns Depressants Moderate
Interaction Summary
Theoretically, berberine might increase the sedative effects of CNS depressants.
Read the full Dihydroberberine + Aminophylline, Amobarbital, Ephedrine interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +2 Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
Read the full Dihydroberberine + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Transfer — through 1 ingredient. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 2c9 (cyp2c9) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Read the full Dihydroberberine + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
Ceylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Amlodipine interactionDihydroberberineAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, berberine might have additive effects with antihypertensive drugs.
Read the full Dihydroberberine + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Transfer — through 2 ingredients. Tap an ingredient for the detail:
DihydroberberineCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
Read the full Dihydroberberine + Amlodipine Benzoate interactionCeylon CinnamonAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Ceylon Cinnamon + Amlodipine Benzoate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Transfer with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dihydroberberine
Cyclosporine (Neoral, Sandimmune)
Berberine can increase serum levels of cyclosporine.
Berberine can reduce metabolism and increase serum levels of cyclosporine. Berberine might inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine.
Anticoagulant/Antiplatelet Drugs
Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, berberine might have additive effects when used with anticoagulant and antiplatelet drugs and increase the risk of bleeding.
Antidiabetes Drugs
Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that berberine may lower blood glucose levels. Theoretically, berberine might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Antihypertensive Drugs
Theoretically, berberine might have additive effects with antihypertensive drugs.
Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone.
Cns Depressants
Theoretically, berberine might increase the sedative effects of CNS depressants.
Animal research suggests that berberine may have sedative effects. Theoretically, use of berberine along with CNS depressants might produce additive therapeutic and adverse effects.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, taking berberine with drugs metabolized by CYP2C9 might increase drug levels and increase the risk of adverse effects.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, use of berberine with drugs metabolized by CYP2D6 might increase drug levels and increase the risk of adverse effects.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, use of berberine with drugs metabolized by CYP3A4 might increase drug levels and increase the risk of adverse effects.
Dextromethorphan (Robitussin Dm, Others)
Theoretically, berberine may increase serum levels of dextromethorphan.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. This may increase the effects and side effects of dextromethorphan.
Losartan (Cozaar)
Berberine might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan.
Metformin (Glucophage)
Theoretically, berberine might increase the therapeutic and adverse effects of metformin.
In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin.
Midazolam (Versed)
Berberine can reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam.
Pentobarbital (Nembutal)
Berberine might increase the sedative effect of pentobarbital.
Evidence from animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, combining berberine and pentobarbital might increase the sedative effects of pentobarbital.
Tacrolimus (Prograf)
Berberine has been associated with increased blood levels of tacrolimus.
In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL.
Acetazolamide
Laboratory studies and initial clinical findings suggest that berberine has the potential to increase acetazolamide concentrations in the body. More research is needed to confirm this interaction.
Ceylon Cinnamon
Antidiabetes Drugs
Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Ceylon cinnamon may lower blood glucose levels. Dose adjustments might be necessary.
Antihypertensive Drugs
Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Animal research shows that Ceylon cinnamon extract has vasorelaxant properties and reduces blood pressure in rat models of hypertension, possibly via inhibition of calcium influx through L-type voltage-sensitive channels.
Brand information
Manufacturer and brand details for Transfer, from the product label.
Cutler Nutrition
See all Cutler Nutrition products- Name
- Cutler Nutrition
- Street Address
- 3625 W Teco Ave Suite 5
- City
- Las Vegas
- State
- NV
- ZipCode
- 89118
- Web Address
- www.JAYCUTLER.com
Transfer by Cutler Nutrition: Common Questions
Does Transfer by Cutler Nutrition interact with any medications?
How can one product interact with so many drugs?
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Does Transfer actually work for blood sugar and cholesterol?
What is dihydroberberine, and is it different from regular berberine?
Can I take Transfer with my diabetes medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Transfer’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Ceylon Cinnamon
Interacts with 258 drugsCeylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evidence for most health benefits is limited...
Read the full Ceylon Cinnamon monograph → Herb & supplement monographBerberine
Interacts with 1,160 drugsBerberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research varies and it is not a replacement for presc...
Read the full Berberine monograph →Sources & How We Checked
Transfer's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 63 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ceylon Cinnamon 22 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Choi HK, Jung GW, Moon KH, et al. Clinical study of SS-Cream in patients with lifelong premature ejaculation. Urology 2000;55:257-61. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Anderson RA, Broadhurst CL, Polansky MM, et al. Isolation and Characterization of Polyphenol Type-A Polymers from Cinnamon with Insulin-like Biological Activity. J Agric Food Chem 2004;52:65-70. PubMed
- Jarvill-Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 2001;20:327-36. PubMed
- Onderoglu S, Sozer S, Erbil KM, et al. The evaluation of long-term effcts of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats. J Pharm Pharmacol 1999;51:1305-12.
- Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
- Ranasinghe P, Jayawardena R, Galappaththy P, et al. Response to Akilen et al. Efficacy and safety of 'true' cinnamon (Cinnamomum zeylanicum) as a pharmaceutical agent in diabetes: a systematic review and meta-analysis. Diabet Med 2013 Apr;30(4):506-7.
- Oliveira JdA, da Silva IC, Trindade LA, et al. Safety and tolerability of essential oil from Cinnamomum zeylanicum blume leaves with action on oral candidosis and its effect on the physical properties of the acylic resin. Evid Based Complement Alternat Me
- Ranasinghe P, Pigera S, Premakumara GA, et al. Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complement Altern Med 2013;13:275. PubMed
- Ranasinghe P, Galappaththy P. Health benefits of Ceylon cinnamon (Cinnamomum zeylanicum): a summary of the current evidence. Ceylon Med J 2016;61(1):1-5. PubMed
- Nyadjeu P, Dongmo A, Nguelefack TB, Kamanyi A. Antihypertensive and vasorelaxant effects of Cinnamomum zeylanicum stem bark aqueous extracts. J Complement Integr Med 2011;8.
- Wansi SL, Nyadjeu P, Ngamga D, et al. Blood pressure lowering effect of the ethanol extract from the stembark of Cinnamomum zeylanicum (lauraceae) in rats. Pharmacol online 2007;3:166-76.
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Ranasinghe P, Jayawardena R, Pigera S, et al. Evaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial. BMC Complement Altern Med 2017;17(1):550. PubMed
- Zareie A, Sahebkar A, Khorvash F, Bagherniya M, Hasanzadeh A, Askari G. Effect of cinnamon on migraine attacks and inflammatory markers: A randomized double-blind placebo-controlled trial. Phytother Res 2020;34(11):2945-52. PubMed
- Zobeiri M, Parvizi F, Shahpiri Z, et al. Evaluation of the effectiveness of cinnamon oil soft capsule in patients with functional dyspepsia: A randomized double-blind placebo-controlled clinical trial. Evid Based Complement Alternat Med 2021;2021:6634115. PubMed
- Chase C, Doyle A, John SS, Laurent T, Griffith S. Post-operative haemorrhage secondary to cinnamon use. A case report. Int J Surg Case Rep 2022;95:107179. PubMed
Berberine 41 references
- Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
- Janbaz KH, Gilani AH. Studies on preventive and curative effects of berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia 2000;71:25-33.. PubMed
- Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
- Zhang Y, Li X, Zou D, et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 2008;93:2559-65. PubMed
- Huang XS, Yang GF, Pan YC. Effect of berberin hydrochloride on blood concentration of cyclosporine A in cardiac transplanted patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28:702-4.
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- Chatterjee P, Franklin MR. Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components. Drug Metab Dispos 2003;31:1391-7. PubMed
- Marin-Neto, J. A., Maciel, B. C., Secches, A. L., and Gallo, Junior L. Cardiovascular effects of berberine in patients with severe congestive heart failure. Clin.Cardiol. 1988;11(4):253-260. PubMed
- Choudhry, V. P., Sabir, M., and Bhide, V. N. Berberine in giardiasis. Indian Pediatr. 1972;9(3):143-146.
- Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
- Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
- Peng, W. H., Hsieh, M. T., and Wu, C. R. Effect of long-term administration of berberine on scopolamine-induced amnesia in rats. Jpn J Pharmacol 1997;74(3):261-266. DOI
- Sharda DC. Berberine in the treatment of diarrhoea of infancy and childhood. J Indian M A 1970;54(1):22-24.
- Sabir M and Bhide NK. Study of some pharmacological actions of berberine. Ind J Physiol & Pharmac 1971;15(3):111-132.
- Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.
- Seery TM and Bieter RN. A contribution to the pharmacology of berberine. J Pharmacol Exp Ther 1940;69:64-67. DOI
- Xin, H. W., Wu, X. C., Li, Q., Yu, A. R., Zhong, M. Y., and Liu, Y. Y. The effects of berberine on the pharmacokinetics of cyclosporin A in healthy volunteers. Methods Find.Exp.Clin Pharmacol 2006;28(1):25-29.
- Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., Huo, L., Wang, M., Hong, J., Wu, P., Ren, G., and Ning, G. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol.Metab 2008;93(7):2559-2565. PubMed
- Yin, J., Xing, H., and Ye, J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism 2008;57(5):712-717. PubMed
- Zhang, H., Wei, J., Xue, R., Wu, J. D., Zhao, W., Wang, Z. Z., Wang, S. K., Zhou, Z. X., Song, D. Q., Wang, Y. M., Pan, H. N., Kong, W. J., and Jiang, J. D. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin re
- Guo, Y., Chen, Y., Tan, Z. R., Klaassen, C. D., and Zhou, H. H. Repeated administration of berberine inhibits cytochromes P450 in humans. Eur J Clin Pharmacol 2012;68(2):213-217. PubMed
- Wei, W., Zhao, H., Wang, A., Sui, M., Liang, K., Deng, H., Ma, Y., Zhang, Y., Zhang, H., and Guan, Y. A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndro
- Marazzi, G., Cacciotti, L., Pelliccia, F., Iaia, L., Volterrani, M., Caminiti, G., Sposato, B., Massaro, R., Grieco, F., and Rosano, G. Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. PubMed
- Meng, S., Wang, L. S., Huang, Z. Q., Zhou, Q., Sun, Y. G., Cao, J. T., Li, Y. G., and Wang, C. Q. Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention. Clin Exp.Pharmacol Physiol 2012;39 PubMed
- Hermann, R. and von, Richter O. Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions. Planta Med 2012;78(13):1458-1477. PubMed
- Chun YT, Yip TT, Lau KL, and et al. A biochemical study on the hypotensive effect of berberine in rats. Gen Pharmac 1979;10:177-182. PubMed
- Saksena HC, Tomar VN, and Soangra MR. Efficacy of a new salt of Berberine Uni-Berberine in oriental sore. Current Medical Practice 1970;14:247-252.
- Abascal K, Yarnell E. Recent clinical advances with berberine. Altern Complement Ther 2010;16(5):281-7. DOI
- Dong H, Zhao Y, Zhao L, Lu F. The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials. Planta Med 2013;79(6):437-46. PubMed
- Hou Q, Han W, Fu X. Pharmacokinetic interaction between tacrolimus and berberine in a child with idiopathic nephrotic syndrome. Eur J Clin Pharmacol 2013;69(10):1861-2. PubMed
- Lan J, Zhao Y, Dong F, et al. Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. J Ethnopharmacol. 2015;161:69-81. PubMed
- Li G, Zhao M, Qiu F, Sun Y, Zhao L. Pharmacokinetic interactions and tolerability of berberine chloride with simvastatin and fenofibrate: an open-label, randomized, parallel study in healthy Chinese subjects. Drug Des Devel Ther. 2018;13:129-139. PubMed
- Ju J, Li J, Lin Q, Xu H. Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials. Phytomedicine. 2018;50:25-34. PubMed
- Xu L, Zhang Y, Xue X, et al. A phase I trial of berberine in Chinese with ulcerative colitis. Cancer Prev Res (Phila). 2020;13(1):117-26. PubMed
- Lyu Y, Zhang Y, Yang M, et al. Pharmacokinetic interactions between metformin and berberine in rats: Role of oral administration sequences and microbiota. Life Sci. 2019;235:116818. PubMed
- Chen YX, Gao QY, Zou TH, et al. Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study. Lancet Gastroenterol Hepatol. 2020;5(3):267-75. PubMed
- Zhang J, Wang Y, Jiang H, et al. Preventive effect of berberine on postoperative atrial fibrillation. Circ Arrhythm Electrophysiol 2022;15(10):e011160. PubMed
- Blais JE, Huang X, Zhao JV. Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. Drugs 2023;83(5):403-427. PubMed
- Panigrahi A, Mohanty S. Efficacy and safety of HIMABERB® Berberine on glycemic control in patients with prediabetes: double-blind, placebo-controlled, and randomized pilot trial. BMC Endocr Disord 2023;23(1):190. PubMed
- Nie Q, Li M, Huang C, et al. The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review. J Transl Med 2024;22(1):225. PubMed
- Koperska A, Moszak M, Seraszek-Jaros A, Bogdanski P, Szulinska M. Does berberine impact anthropometric, hepatic, and metabolic parameters in patients with metabolic dysfunction-associated fatty liver disease? Randomized, double-blind placebo-controlled tr
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC