Major interaction on record — check this product against your medications before combining. Based on 7 of 9 ingredients. Check your meds →
Dietary supplement

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 Ingredients & Drug Interactions

by V1 Nutra

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking V1 x Panda Ultimate Pandamus Pre-Workout Level 1 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 is a dietary supplement by V1 Nutra with 9 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 398 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Agmatine Sulfate, Mucuna pruriens Seed Extract, Powder, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra

Ask about any prescription or over-the-counter medication and we check it for interactions with V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains 9 ingredients, 7 of which are active compounds. L-Citrulline supports blood vessel function and is used in pre-workout formulas to boost exercise performance.

L-Tyrosine is an amino acid that supports brain function and mental clarity during physical stress. Beta-Alanine helps muscles buffer fatigue during intense exercise.

Agmatine Sulfate is included for its theoretical effects on blood vessel function. Betaine Anhydrous supports muscle and liver health.

Alpha-Glycerylphosphorylcholine (alpha-GPC) is a compound thought to support brain function and muscle performance. Mucuna pruriens Seed Extract is a plant source of levodopa, an active compound traditionally used in herbal medicine.

VasoDrive-AP and AstraGin are proprietary blends with no interaction data available to us. The product also contains inactive ingredients—malic acid, citric acid, silicon dioxide, natural and artificial flavors, sucralose, acesulfame potassium, and food coloring—used as fillers, binders, and for taste.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Pre-workout exercise performance and energy.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Fatigue, Muscle strength, Physical performance, Endurance — and 2 related terms.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Physical performance.
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.

Evidence for this product's active ingredients is mixed. L-Citrulline and Beta-Alanine are both possibly effective for athletic performance, which is what this pre-workout claims to support.

L-Tyrosine is possibly effective for cognitive function and memory. The other active ingredients—Agmatine Sulfate, Betaine Anhydrous, Alpha-GPC, and Mucuna pruriens—don't have established effectiveness ratings for athletic performance in our data; their evidence is either insufficient or not rated for that use.

The product itself isn't rated as a whole, so what matters is how the checked ingredients perform for your goal. If you're buying it to boost workout performance, the citrulline and beta-alanine have some science behind them, but the other components are less clear.

The evidence, ingredient by ingredient L-citrulline Tyrosine Beta-alanine Agmatine Betaine Anhydrous Alpha-gpc Cowhage

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in healthy adults when used short-term, but several carry important caveats. L-Citrulline and L-Tyrosine commonly cause heartburn and gastrointestinal discomfort.

Beta-Alanine causes a harmless but noticeable tingling sensation (paresthesia) on the skin, usually on the scalp within 20 minutes, spreading across the body and lasting about an hour—it's mild at lower doses but can feel severe at higher ones. Agmatine Sulfate can cause diarrhea and nausea.

Betaine Anhydrous may cause body odor and diarrhea. Mucuna pruriens can cause flatulence, diarrhea, nausea, and insomnia.

Alpha-GPC is rarely associated with dizziness, headache, and insomnia, and long-term use (at least 2 months) has been rarely linked to stroke. During pregnancy, the safety data advises against L-Citrulline, L-Tyrosine, Beta-Alanine, Agmatine Sulfate, and Alpha-GPC—there isn't enough information to know they're safe.

For Betaine Anhydrous and Mucuna pruriens, we have no pregnancy data on file. While breastfeeding, avoid L-Citrulline, Beta-Alanine, and Agmatine Sulfate.

Mucuna pruriens may lower prolactin and reduce milk supply, so it's best avoided. L-Tyrosine and Betaine Anhydrous lack breastfeeding safety data; Alpha-GPC has insufficient data as well.

Side effects, ingredient by ingredient L-citrulline Tyrosine Beta-alanine Agmatine Betaine Anhydrous Alpha-gpc Cowhage

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 7 matched ingredients can interact with medications — Cowhage, Tyrosine, Alpha-gpc, L-citrulline, Agmatine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; Parkinson's medications.
  • For scale: 398 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Stop and check with your pharmacist if you take methyldopa, monoamine oxidase inhibitors (MAOIs), levodopa (for Parkinson's), antihypertensive (blood pressure) drugs, antidiabetes medications, antipsychotics, tricyclic antidepressants, scopolamine (Transderm Scop), or guanethidine. These carry Major or Moderate interaction risks with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This pre-workout is built around ingredients with some evidence for exercise performance, but it carries serious medication interactions—especially if you take blood pressure drugs, antidepressants, diabetes medications, or Parkinson's treatment. The tingling from beta-alanine is harmless but real and can be intense.

If you're pregnant or breastfeeding, talk with your doctor before starting. Check your medications with the tool on this page before you buy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about V1 x Panda Ultimate Pandamus Pre-Workout Level 1 , straight from the product label.

Brand V1 Nutra
Barcode (UPC) 051497444624
Net contents 21.31 Ounce(s); 604 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 317710
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15.1 Gram(s), 30.2 Gram(s)
Maximum serving Sizes:
15.1 Gram(s), 30.2 Gram(s)
Servings per container
20
UPC/BARCODE
051497444624
IngredientAmount% DV
L-Citrulline5500 mg, 11000 mg--
L-Tyrosine2500 mg, 5000 mg--
Beta-Alanine1600 mg--
Agmatine Sulfate500 mg, 1000 mg--
Betaine Anhydrous2500 mg, 5000 mg--
Alpha Glycerylphosphorylcholine300 mg, 600 mg--
VasoDrive-AP254 mg, 508 mg--
Mucuna pruriens Seed Extract, Powder50 mg, 100 mg--
AstraGin25 mg, 50 mg--

Other ingredients: Malic Acid, Citric Acid, Silicon Dioxide, Natural & Artificial Flavors, Sucralose, Acesulfame Potassium, FD&C Red #40, FD&C Blue #1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Contains: Milk This product is manufactured in a facility that also processes other products which may contain milk, eggs, fish, shellfish, tree nuts, peanuts, soy, wheat, and sesame.

Seals/Symbols

GMP Quality Good Manufacturing Practice Certification

General Statements

Servings Per Container: 40 (1 Scoop) / 20 (2 Scoops)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size15.1 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Citrulline

Interacts with
178 drugs
5500 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

L-Tyrosine

Interacts with
21 drugs
2500 mg per serving

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performan...

L-Tyrosine monograph & interactions

Beta-Alanine

No known
interactions
1600 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Agmatine Sulfate

Interacts with
258 drugs
500 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

Betaine Anhydrous

No known
interactions
2500 mg per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

Alpha Glycerylphosphorylcholine

Interacts with
16 drugs
300 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha Glycerylphosphorylcholine monograph & interactions

VasoDrive-AP

254 mg per serving Form: Casein Hydrolysate

Mucuna pruriens Seed Extract, Powder

Interacts with
193 drugs
50 mg per serving Form: L-Dopa

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna pruriens Seed Extract, Powder monograph & interactions

AstraGin

25 mg per serving Form: Astragalus membranaceus, Fractionated, Purified, Panax notoginseng, Fractionated, Purified

Other (inactive) ingredients: Malic Acid, Citric Acid, Silicon Dioxide, Natural & Artificial Flavors, Sucralose, Acesulfame Potassium, FD&C Red #40, FD&C Blue #1. These complete the product’s ingredient list but are not active constituents.

Interaction report

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra Drug Interactions

Want to check YOUR meds against V1 x Panda Ultimate Pandamus Pre-Workout Level 1 ?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
398Drugs
17 Major 365 Moderate 16 Minor

Ingredients driving the most interactions

Agmatine Sulfate 258
Mucuna pruriens Seed Extract, Powder 193
L-Citrulline 178
L-Tyrosine 21
Alpha Glycerylphosphorylcholine 16

Individual Drug Interactions

The ingredients in V1 x Panda Ultimate Pandamus Pre-Workout Level 1 interact with 398 drugs. Click any drug to see the details.

5 of the 9 ingredients in V1 x Panda Ultimate Pandamus Pre-Workout Level 1 interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate Mucuna pruriens Seed Extract, Powder L-Citrulline L-Tyrosine Alpha Glycerylphosphorylcholine

Each ingredient & the kinds of drugs it affects

For each ingredient in V1 x Panda Ultimate Pandamus Pre-Workout Level 1 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions

Mucuna pruriens Seed Extract, Powder8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna pruriens Seed Extract, Powder full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
L-Tyrosine full monograph & interactions

Alpha Glycerylphosphorylcholine1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
Alpha Glycerylphosphorylcholine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for V1 x Panda Ultimate Pandamus Pre-Workout Level 1 , from the product label.

V1 Nutra

See all V1 Nutra products
Name
V1 Nutra
Pharmacist Counseling Corner

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra: Common Questions

Does V1 x Panda Ultimate Pandamus Pre-Workout Level 1 by V1 Nutra interact with any medications?
Yes. Based on its ingredients, V1 x Panda Ultimate Pandamus Pre-Workout Level 1 has a known interaction with 398 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
V1 x Panda Ultimate Pandamus Pre-Workout Level 1 contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the tingling sensation I might feel from this pre-workout?
That's beta-alanine, one of the active ingredients. It causes a harmless pins-and-needles feeling (paresthesia) that usually starts on your scalp within 20 minutes and spreads across your body, lasting about an hour. It's mild at lower doses and more intense at higher ones—completely harmless but noticeable.
Can I take this if I have heartburn?
L-Citrulline and L-Tyrosine in this product commonly cause heartburn and stomach discomfort. If you're prone to reflux or heartburn, this might make it worse. Talk to your pharmacist about whether it's a good fit for you.
Does this product actually improve workout performance?
L-Citrulline and Beta-Alanine both have possibly effective evidence for athletic performance, so there's some science there. The other active ingredients don't have clear evidence for that specific use, so the product's overall effectiveness depends mainly on those two.
What does Mucuna pruriens do in this formula?
Mucuna pruriens is a plant that contains levodopa, an active compound. It's traditionally used in herbal medicine, but we don't have established effectiveness ratings for athletic performance. It does carry serious medication interactions, especially with blood pressure drugs, antidepressants, and Parkinson's medications.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data for most of these ingredients during pregnancy or breastfeeding. L-Citrulline, L-Tyrosine, Beta-Alanine, and Agmatine Sulfate are best avoided in both. Mucuna pruriens may also lower milk supply if you're nursing. Talk with your doctor or pharmacist about whether this product is right for you.
What are the inactive ingredients in this powder?
The inactive ingredients are malic acid, citric acid, silicon dioxide, natural and artificial flavors, sucralose, acesulfame potassium, and food coloring (FD&C Red #40 and FD&C Blue #1). These are fillers and binders used to make the powder taste better and mix well.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if V1 x Panda Ultimate Pandamus Pre-Workout Level 1 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 label
Go deeper

The Full Monographs Behind V1 x Panda Ultimate Pandamus Pre-Workout Level 1 ’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Tyrosine

Interacts with 21 drugs

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss,...

Read the full Tyrosine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph → Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph →
Sources

Sources & How We Checked

V1 x Panda Ultimate Pandamus Pre-Workout Level 1 's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 55 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-citrulline 8 references
  1. Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
  2. Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
  3. Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
  4. Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
  5. Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
  6. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
  7. Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
  8. Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed

See these in context on the L-citrulline monograph →

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
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Agmatine 3 references
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Betaine Anhydrous 11 references
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See these in context on the Betaine Anhydrous monograph →

Alpha-gpc 4 references
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  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Cowhage 12 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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