Vardenafil

Name: Vardenafil Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

78 interactions 5 explained in plain English

Also sold as: Levitra Levitra® Staxyn Staxyn®

About Vardenafil

Vardenafil is a phosphodiesterase inhibitor used to treat erectile dysfunction in men. Read the full Vardenafil drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nitroglycerin Nitroglycerin Topical Nitroglycerin Sublingual Nitroglycerin Spray Isosorbide Dinitrate Ketoconazole Topical

8 Contraindicated 65 Major 5 Moderate

All (78) Contraindicated (8) Major (65) Moderate (5)

Moderate

Vardenafil Trospium / Xanomeline Cobenfy Explained Increased oral sensitive CYP3A4 substrate exposure and an increased risk on severity and frequency of sensitive CYP3A4 substrate-r... Details Vardenafil Abiraterone Abirtega Increased vardenafil exposure Details Vardenafil Cyclosporine Injection Atopica Increased vardenafil exposure Details Vardenafil Cyclosporine Ophthalmic Cequa Increased vardenafil exposure Details Vardenafil Letermovir Injection Prevymis Increased vardenafil exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.