Drug & supplement interaction

Arabinoxylan + Diltiazem

Diltiazem brand names: Cardizem, Cardizem SR, Diltiaz SR, Cardizem CD, Tiazac, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Arabinoxylan and Diltiazem in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Arabinoxylan and Diltiazem

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diltiazem and Arabinoxylan in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Arabinoxylan safety at a glance

Arabinoxylan overall Use caution Generally considered well tolerated as a food-derived fiber, but high-quality long-term safety data are limited.
Pregnancy Use caution Not enough reliable data on supplement use; stick to fiber from normal foods unless your provider advises otherwise.
Breastfeeding Use caution There is little safety information for supplements while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diltiazem and Arabinoxylan? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Diltiazem

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diltiazem is filed under 9 classifications — including calcium channel blockers, cytochrome p450 1a2 (cyp1a2) inhibitors, cytochrome p450 3a4 (cyp3a4) inhibitors. Arabinoxylan has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Diltiazem’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Arabinoxylan Does Interact With Other Medications

Arabinoxylan has 86 moderate known drug interactions in our database — Diltiazem isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Diltiazem)
Taking anything else?

Check Another of Your Medications Against Arabinoxylan

Covers the 2,830 medications we’ve checked against Arabinoxylan. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Arabinoxylan and Diltiazem May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Bloating or gas / Diarrhea reported in 6.1% of FDA reports for Diltiazem Additional detail

    Arabinoxylan

    “Orally, arabinoxylan seems to be well tolerated. Some adverse effects reported in clinical trials include diarrhea, gas, bloating, and abdominal pain.”

    Arabinoxylan · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 25664. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
    2. 99677. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
    3. 99680. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

    “Orally, arabinoxylan can cause gastrointestinal adverse effects such as diarrhea, gas, bloating, and abdominal pain.”

    Arabinoxylan · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 25664. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
    2. 99677. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
    3. 99680. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

    Diltiazem

    Listed in the ADVERSE REACTIONS section of the FDA label for Diltiazem, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Arabinoxylan but not commonly for Diltiazem: stomach pain.

Effects for Diltiazem come from the ADVERSE REACTIONS section of its FDA label; effects for Arabinoxylan come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 34,400 voluntary FDA FAERS reports for Diltiazem that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Arabinoxylan or Diltiazem

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Arabinoxylan or Diltiazem, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Diltiazem

This page covers Arabinoxylan only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diltiazem page lists 260 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Coleus (major) and Grapefruit (major).

By severity: 7 major · 214 moderate · 39 minor.

From our pharmacist’s overview on the Diltiazem page

“Someone on diltiazem (Cardizem, Tiazac) is usually managing blood pressure, angina, or a fast heart rhythm, so this list deserves genuine care. Seven of the 260 ingredients on file carry a major rating, and two of those are things people actually buy: grapefruit, which blocks the enzyme that clears diltiazem and can push its blood leve…”

Reviewed by 2 · Jul 18, 2026

Open the Diltiazem interaction page

One more smart check

Taking Arabinoxylan as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Arabinoxylan, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Arabinoxylan. Even though Arabinoxylan itself has no known interaction with Diltiazem, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Arabinoxylan and Diltiazem Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Arabinoxylan
Steady interest

#956 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diltiazem
Top 10%

#201 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Arabinoxylan reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Arabinoxylan and Diltiazem records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Arabinoxylan

What is Arabinoxylan?

Arabinoxylan
  • Blood sugar support
  • Digestive and gut health (prebiotic)
  • Cholesterol and triglyceride support
  • Immune support
  • Metabolic syndrome

Arabinoxylan is a type of dietary fiber found in cereal grains that acts as a prebiotic and may modestly affect blood sugar and blood fats. The evidence for most uses is early and limited, so it should not replace proven treatments. If you are considering it, talk with your pharmacist or doctor first.

Fiber extracted from the cell walls of cereal grains (such as wheat bran, rice bran, corn, rye, oat, and barley) · Powder, capsules, and a modified rice-bran product known as MGN-3 (Biobran)

An interaction check asks whether these two react with each other — it does not ask whether Arabinoxylan is a good idea for someone in your situation. Here is what our Arabinoxylan record says about it on its own.

Arabinoxylan: dosing

There is no official or standardized dose of arabinoxylan, and amounts used in studies have varied widely depending on the product and the goal.The best approach is to follow the directions on the specific product label and to start low and increase slowly to limit gas and bloating.

From our Arabinoxylan monograph — the full record covers uses, side effects and every documented interaction.

Read the full Arabinoxylan monograph & all interactions
Medication

About Diltiazem

What Is Diltiazem Used For?

Brand names: Cardizem, Cardizem SR, Diltiaz SR, Cardizem CD, Tiazac, Diltiaz XT, Diltiaz CD, Dilacor, Diltiaz, Cardizem LA, Dilacor XR, Cartia XT, Tiamate, Adizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Dilcardia SR, Dilzem SR, Dilzem XL, Slozem, Tildiem LA, Tildiem Retard, Viazem XL, Zemtard 120XL, Zemtard 180XL, Zemtard 240XL, Zemtard 300XL

Oral extended-release forms of diltiazem — including Matzim LA, Cardizem LA, Cartia, Cartia XT, Tiadylt ER, and various generic capsules and tablets — are used to treat high blood pressure (hypertension) and chronic stable angina (chest pain brought on by activity). Some capsule formulations, including Cartia, Cartia XT, and certain generics, are also approved for angina due to coronary artery spasm (sudden chest pain caused by a sudden tightening of a coronary artery).

Injectable forms of diltiazem are used in hospital settings to temporarily slow a dangerously fast heart rate in atrial fibrillation or atrial flutter (rapid, irregular heart rhythms), and to restore a normal heart rhythm in paroxysmal supraventricular tachycardia (PSVT) — sudden episodes of a very fast but regular heartbeat originating above the heart's lower chambers.

Most-Reported Side Effects for Diltiazem

From FAERS, the FDA’s public side-effect reporting system (34,400 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 3,309 reports
Fatigue 2,733 reports
Nausea 2,454 reports
Dizziness 2,174 reports
Diarrhea 2,113 reports
See full Diltiazem drug information
Keep checking

Other Drugs & Arabinoxylan

Browse every other medication we’ve checked against Arabinoxylan — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Arabinoxylan page.

No interaction 2,743 drugs checked — show the list

We also checked Arabinoxylan against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Arabinoxylan list.

See the full Arabinoxylan interactions page
See every supplement checked against Diltiazem, ranked by severity
Evidence & sources

Arabinoxylan References

The 8 references that drive our Arabinoxylan monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Grasten S, Liukkonen K-H, Chrevatidis A, et al. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutrition Res 2003;23:1503-14. DOI
  2. Lu ZX, Walker KZ, Muir JG, Mascara T, O'Dea K. Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr 2000;71(5):1123-1128.
  3. Lu ZX, Walker KZ, Muir JG, O'Dea K. Arabinoxylan fibre improves metabolic control in people with Type II diabetes. Eur J Clin Nutr 2004;58(4):621-8. PubMed
  4. Garcia AL, Otto B, Reich SC, et al. Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance. Eur J Clin Nutr 2007;61(3):334-41. PubMed
  5. Garcia AL, Steiniger J, Reich SC, et al. Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance. Horm Metab Res 2006;38(11):761-766. PubMed
  6. François IE, Lescroart O, Veraverbeke WS, et al. Effects of a wheat bran extract containing arabinoxylan oligosaccharides on gastrointestinal health parameters in healthy adult human volunteers: a double-blind, randomised, placebo-controlled, cross-over t
  7. Schioldan AG, Gregersen S, Hald S, et al. Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome. Eur J Nutr. 2018 Mar;57(2):795-807. PubMed
  8. Scarpellini E, Deloose E, Vos R, et al, The effect of arabinoxylooligosaccharides on gastric sensory-motor function and nutrient tolerance in man. Neurogastroenterol Motil. 2016 Aug;28(8):1194-203. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Arabinoxylan and Diltiazem Together: Common Questions

Is it safe to take Arabinoxylan with Diltiazem?
We do not list a known interaction between Arabinoxylan and Diltiazem. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Arabinoxylan and Diltiazem have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Arabinoxylan and Diltiazem combination checked?
Interactions in our licensed database are recorded against drug classes. Diltiazem is filed under 9 classifications, and Arabinoxylan has documented interactions with 1 drug class — none of Diltiazem's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Arabinoxylan interact with any other medications?
Yes. Arabinoxylan has 86 documented drug interactions in our database — Diltiazem is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Diltiazem interact with any supplements?
Yes. Diltiazem has documented interactions with 260 supplements in our database — Arabinoxylan is not one of them. The Diltiazem interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Arabinoxylan monograph Uses, safety profile, and every drug interaction in one place Diltiazem drug information The full plain-English guide to this medication Diltiazem supplement interactions Every supplement checked against Diltiazem, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diltiazem and Arabinoxylan?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.