Drug & supplement interaction

Coriander + Bendamustine Hydrochloride

Bendamustine Hydrochloride brand name: Bendeka.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Coriander and Bendamustine Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Coriander and Bendamustine Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Bendamustine Hydrochloride and Coriander in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Coriander safety at a glance

Coriander overall Generally safe Coriander is generally safe in normal food amounts for most people.
Pregnancy Use caution Food amounts are likely fine, but concentrated medicinal doses or essential oil should be avoided without medical advice.
Breastfeeding Use caution Food amounts are likely fine, but medicinal doses lack safety data, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Bendamustine Hydrochloride and Coriander? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Bendamustine Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Bendamustine Hydrochloride is filed under 3 classifications — alkylating agents, cytochrome p450 1a2 (cyp1a2) substrates, cytochrome p450 1a2 (cyp1a2) substrates. Coriander has documented interactions with 4 drug classes — the most serious being antidiabetes drugs (moderate), antihypertensive drugs (moderate) and cns depressants (moderate) — and none of Bendamustine Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Coriander Does Interact With Other Medications

Coriander has 717 moderate known drug interactions in our database — Bendamustine Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Moderate 717 No known interaction 2,113 (incl. Bendamustine Hydrochloride)
Taking anything else?

Check Another of Your Medications Against Coriander

Covers the 2,830 medications we’ve checked against Coriander. Pick one to open its full report.

What to actually watch for

What Coriander Itself Has Been Linked To

This is not an interaction — nothing below involves Bendamustine Hydrochloride. It is the side-effect record for Coriander on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Coriander, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Wheezing / Hives Worth acting on Additional detail

    “A case of anaphylactic reaction characterized by generalized urticaria, conjunctivitis, oropharyngeal angioedema, and bronchospasms has been reported in a 25-year-old spice worker who consumed food containing coriander fruit. The digestive spice allergy was attributed to sensitization to coriander caused by occupational exposure to coriander fruit, powder, and dust.”

    Coriander · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    5 sources cited
    1. 46192. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
    2. 46226. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
    3. 46245. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
    4. 19. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
    5. 46168. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  • A severe allergic reaction Worth acting on Additional detail

    “Orally and topically, coriander seems to be well tolerated.

    Most Common Adverse Effects:

    Topically: Contact dermatitis in sensitive individuals.

    Serious Adverse Effects (Rare):

    Orally: Anaphylaxis in sensitive individuals.”

    Coriander · Natural Medicines adverse-effect record, reported in dermatitis.

  • A stuffy or runny nose Additional detail

    Recorded for Coriander in the same Natural Medicines adverse-effect record shown under Wheezing / Hives above.

  • Itching Additional detail

    “Topically, coriander can cause pruritus and a burning sensation.”

    Coriander · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 97874. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed
  • A skin rash Additional detail

    Recorded for Coriander in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

Everything above comes from the Natural Medicines adverse-effect record for Coriander — expand a row for the licensed statement it rests on. We haven’t matched Bendamustine Hydrochloride to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Bendamustine Hydrochloride.

Everything else you take

See Every Supplement That Interacts With Bendamustine Hydrochloride

This page covers Coriander only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bendamustine Hydrochloride page lists 86 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Acerola (moderate), Adrafinil (moderate), African Wild Potato (moderate), Alpha-lipoic Acid (moderate) and Ashitaba (moderate).

By severity: 62 moderate · 24 minor.

From our pharmacist’s overview on the Bendamustine Hydrochloride page

“Bendamustine (Bendeka), a chemotherapy used for certain leukemias and lymphomas, carries 86 supplement and herbal interactions on file, and none of them rates major, so this is a watch-and-adjust list rather than an alarm. Nearly all of the entries, about 80, involve the same liver enzyme, CYP1A2, which helps process bendamustine.”

Reviewed by 2 · Jul 18, 2026

Open the Bendamustine Hydrochloride interaction page

One more smart check

Taking Coriander as Part of a Dietary Supplement Product? Check It for Interactions

We hold 934 real supplement products containing Coriander, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Coriander. Even though Coriander itself has no known interaction with Bendamustine Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Coriander and Bendamustine Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Coriander
Top 25%

#264 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Bendamustine Hydrochloride
Top half

#896 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Coriander reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Coriander and Bendamustine Hydrochloride records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Coriander

What is Coriander?

Coriander
  • Digestive upset and gas
  • Appetite stimulation
  • Mild antimicrobial (topical)
  • Diarrhea and IBS symptoms
  • General flavoring and traditional remedy

Coriander (also called cilantro) is a common cooking herb and spice that has long been used in traditional medicine for digestive complaints. As a food it is generally safe for most people, but high-quality human studies supporting its medicinal benefits are limited. Talk with your pharmacist or doctor before using concentrated extracts or essential oils.

Coriandrum sativum · Apiaceae · Seeds (fruit), leaves, and essential oil · Culinary spice and herb, tea, capsules, tincture/extract, essential oil

An interaction check asks whether these two react with each other — it does not ask whether Coriander is a good idea for someone in your situation. Here is what our Coriander record says about it on its own.

Coriander: dosing

There is no standardized or proven medicinal dose of coriander. Amounts used in studies and traditional remedies vary widely depending on the form (tea, seeds, capsule, or oil).If you choose to use a coriander supplement, follow the directions on the product label and do not exceed the recommended amount. Essential oils are very concentrated and should not be taken by mouth without professional guidance.

From our Coriander monograph — the full record covers uses, side effects and every documented interaction.

Read the full Coriander monograph & all interactions
Medication

About Bendamustine Injection

What Is Bendamustine Injection Used For?

Brand name: Bendeka

Bendamustine hydrochloride injection is used to treat adults with chronic lymphocytic leukemia (CLL). It is also used for adults with indolent B-cell non-Hodgkin lymphoma (NHL) — a slow-growing type of blood cancer — when the disease has continued to progress during or within six months of treatment with rituximab or a rituximab-containing regimen.

For CLL, how well bendamustine works compared to other first-line treatments (aside from chlorambucil) has not been fully established.

Most-Reported Side Effects for Bendamustine Hydrochloride

From FAERS, the FDA’s public side-effect reporting system (11,906 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fever 861 reports
Disease progression 572 reports
Rash 556 reports
Febrile neutropenia 535 reports
Neutropenia 501 reports
See full Bendamustine Injection drug information
Keep checking

Other Drugs & Coriander

Browse every other medication we’ve checked against Coriander — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
717Moderate
0Minor
2,112No known interaction
717 Moderate 2,112 No interaction
Moderate

717 interactions

Showing 60 of 717 moderate interactions — see all 717 on the Coriander page.

No interaction 2,112 drugs checked — show the list

We also checked Coriander against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,112 medications checked with no known interaction — see the full Coriander list.

See the full Coriander interactions page
See every supplement checked against Bendamustine Hydrochloride, ranked by severity
Evidence & sources

Coriander References

The 12 references that drive our Coriander monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed
  3. Gray, A. M. and Flatt, P. R. Insulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander). Br.J Nutr. 1999;81(3):203-209.
  4. Kanerva, L. and Soini, M. Occupational protein contact dermatitis from coriander. Contact Dermatitis 2001;45(6):354-355. PubMed
  5. Emamghoreishi, M., Khasaki, M., and Aazam, M. F. Coriandrum sativum: evaluation of its anxiolytic effect in the elevated plus-maze. J Ethnopharmacol. 1-15-2005;96(3):365-370. PubMed
  6. Ebo, D. G., Bridts, C. H., Mertens, M. H., and Stevens, W. J. Coriander anaphylaxis in a spice grinder with undetected occupational allergy. Acta Clin Belg. 2006;61(3):152-156. PubMed
  7. Eidi, M., Eidi, A., Saeidi, A., Molanaei, S., Sadeghipour, A., Bahar, M., and Bahar, K. Effect of coriander seed (Coriandrum sativum L.) ethanol extract on insulin release from pancreatic beta cells in streptozotocin-induced diabetic rats. Phytother.Res
  8. Jabeen, Q., Bashir, S., Lyoussi, B., and Gilani, A. H. Coriander fruit exhibits gut modulatory, blood pressure lowering and diuretic activities. J Ethnopharmacol. 2-25-2009;122(1):123-130. PubMed
  9. van Toorenenbergen, A. W. and Dieges, P. H. Immunoglobulin E antibodies against coriander and other spices. J Allergy Clin Immunol. 1985;76(3):477-481. PubMed
  10. Ashwood-Smith, M. J., Warrington, P. J., Jenkins, M., Ceska, O., and Romaniuk, P. J. Photobiological properties of a novel, naturally occurring furoisocoumarin, coriandrin. Photochem.Photobiol. 1989;50(6):745-751. PubMed
  11. Sastre, J., Olmo, M., Novalvos, A., Ibanez, D., and Lahoz, C. Occupational asthma due to different spices. Allergy 1996;51(2):117-120. PubMed
  12. Beikert FC, Anastasiadou Z, Fritzen B, Frank U, Augustin M. Topical treatment of tinea pedis using 6% coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study. Dermatology. 2013;226(1):47-51. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Coriander and Bendamustine Hydrochloride Together: Common Questions

Is it safe to take Coriander with Bendamustine Hydrochloride?
We do not list a known interaction between Coriander and Bendamustine Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Coriander and Bendamustine Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Bendamustine Hydrochloride is filed under 3 classifications, and Coriander has documented interactions with 4 drug classes — none of Bendamustine Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Coriander interact with any other medications?
Yes. Coriander has 717 documented drug interactions in our database — Bendamustine Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Bendamustine Hydrochloride interact with any supplements?
Yes. Bendamustine Hydrochloride has documented interactions with 86 supplements in our database — Coriander is not one of them. The Bendamustine Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Coriander monograph Uses, safety profile, and every drug interaction in one place Bendamustine Injection drug information The full plain-English guide to this medication Bendamustine Hydrochloride supplement interactions Every supplement checked against Bendamustine Hydrochloride, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Bendamustine Hydrochloride and Coriander?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.