Drug & supplement interaction

Fulvic Acid + Insulin (rDNA)

Insulin (rDNA) brand names: Humalog, Humalog Mix 75/25, Humulin R, Humulin N, Humulin L, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Fulvic Acid and Insulin (rDNA) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Insulin (rDNA) states a food rule worth keeping to.

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Interaction report

Fulvic Acid and Insulin (rDNA)

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Insulin (rDNA) and Fulvic Acid in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Fulvic Acid safety at a glance

Fulvic Acid overall Use caution Short-term use appears generally tolerated, but high-quality safety data in humans is limited.
Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Insulin (rDNA) and Fulvic Acid? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Insulin (rDNA)

Interactions in our licensed database are recorded against drug classes, not just single drug names. Insulin (rDNA) is filed under 2 classifications — including antidiabetes drugs. Fulvic Acid has documented interactions with 3 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), immunosuppressants (moderate) and thyroid hormone (moderate) — and none of Insulin (rDNA)’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Fulvic Acid Does Interact With Other Medications

Fulvic Acid has 257 moderate known drug interactions in our database — Insulin (rDNA) isn’t one of them. If you take anything else, check it against the full list below.

Moderate 257 No known interaction 2,573 (incl. Insulin (rDNA))
Taking anything else?

Check Another of Your Medications Against Fulvic Acid

Covers the 2,830 medications we’ve checked against Fulvic Acid. Pick one to open its full report.

What to actually watch for

What Fulvic Acid Itself Has Been Linked To

This is not an interaction — nothing below involves Insulin (rDNA). It is the side-effect record for Fulvic Acid on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Fulvic Acid, this list is the first place to look.

  • Sore throat / Diarrhea Additional detail

    “In one clinical trial, fulvic acid 3.8% 40 mL taken orally twice daily resulted in diarrhea and sore throat in some patients.”

    Fulvic Acid · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 90589. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed
  • Headache Additional detail

    “In one clinical trial, fulvic acid 3.8% 40 mL taken orally twice daily resulted in headache in some patients.”

    Fulvic Acid · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 90589. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Fulvic Acid — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Insulin (rDNA)’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Insulin (rDNA) column appears here.

How to take them

Some Insulin (rDNA) Products Have a Food Rule — Fulvic Acid Should Not Break It

At least one FDA label for a product containing Insulin (rDNA) says to take it with food. If you take Fulvic Acid on an empty stomach out of habit, keep them separate — and take Insulin (rDNA) with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Insulin (rDNA) products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.1 , 2.2 , 2.3 , 2.4 ) Subcutaneous injection ( 2.2 ): Administer HUMALOG ® U-100 or U-200 by subcutaneous injection into the abdominal wall, thigh, upper arm, or buttocks within 15 minutes before a meal or immediately after a meal.

From the Dosage and Administration section of the FDA label we read for Insulin (rDNA) — where that label names a specific product, the instruction is that product's. See the Insulin (rDNA) drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Insulin (rDNA)

This page covers Fulvic Acid only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Insulin (rDNA) page lists 242 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Chelation Therapy Products (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 211 moderate · 29 minor.

From our pharmacist’s overview on the Insulin (rDNA) page

“A weed called Siberian cocklebur has caused severe low blood sugar in humans and is the one ingredient to avoid outright while using insulin (rDNA) products like Humalog or Humulin. This list deserves real respect.”

Reviewed by 2 · Jul 18, 2026

Open the Insulin (rDNA) interaction page

One more smart check

Taking Fulvic Acid as Part of a Dietary Supplement Product? Check It for Interactions

We hold 294 real supplement products containing Fulvic Acid, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Fulvic Acid. Even though Fulvic Acid itself has no known interaction with Insulin (rDNA), another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Fulvic Acid and Insulin (rDNA) Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Fulvic Acid
Top half

#438 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Insulin (rDNA)
Top 25%

#608 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Fulvic Acid reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Fulvic Acid and Insulin (rDNA) records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Fulvic Acid

What is Fulvic Acid?

  • General wellness and energy
  • Gut health
  • Antioxidant support
  • Mineral and nutrient supplementation
  • Immune support

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall wellness. Human research is very limited, so most claims are unproven. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding due to a lack of safety data.

Derived from humus, soil, peat, and decomposed plant matter (often sourced from shilajit or leonardite) · Liquid drops, capsules, powders, shilajit resin, mineral supplements

An interaction check asks whether these two react with each other — it does not ask whether Fulvic Acid is a good idea for someone in your situation. Here is what our Fulvic Acid record says about it on its own.

Fulvic Acid: dosing

There is no official or standardized dose for fulvic acid. Products vary widely in concentration and form, including drops, capsules, and powders.The safest approach is to follow the directions on the product label and start with the lowest suggested amount.

From our Fulvic Acid monograph — the full record covers uses, side effects and every documented interaction.

Read the full Fulvic Acid monograph & all interactions
Medication

About Insulin Lispro Injection

What Is Insulin Lispro Injection Used For?

Brand names: Humalog, Humalog Mix 75/25, Humulin R, Humulin N, Humulin L, Humulin 50/50, Humulin 70/30, Humulin U, NovoLog, Velosulin, Novolog Mix 70/30, Actrapid, Humulin S, Insuman Rapid

Insulin lispro injection is used to improve glycemic control (blood sugar management) in people with diabetes mellitus. It is a rapid-acting insulin analog approved for use in both type 1 and type 2 diabetes.

Admelog is specifically indicated to improve glycemic control in patients with diabetes mellitus. Humalog Mix75/25 is indicated to improve glycemic control in adults with diabetes mellitus; it is a fixed-ratio mixture of insulin lispro and insulin lispro protamine, and its fixed proportions do not allow for separate adjustment of basal (background) and prandial (mealtime) doses.

See full Insulin Lispro Injection drug information
Keep checking

Other Drugs & Fulvic Acid

Browse every other medication we’ve checked against Fulvic Acid — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
257Moderate
0Minor
2,572No known interaction
257 Moderate 2,572 No interaction
Moderate

257 interactions

Showing 60 of 257 moderate interactions — see all 257 on the Fulvic Acid page.

No interaction 2,572 drugs checked — show the list

We also checked Fulvic Acid against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,572 medications checked with no known interaction — see the full Fulvic Acid list.

See the full Fulvic Acid interactions page
See every supplement checked against Insulin (rDNA), ranked by severity
Evidence & sources

Fulvic Acid References

The 3 references that drive our Fulvic Acid monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Fulvic Acid and Insulin (rDNA) Together: Common Questions

Is it safe to take Fulvic Acid with Insulin (rDNA)?
We do not list a known interaction between Fulvic Acid and Insulin (rDNA). That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Fulvic Acid and Insulin (rDNA) at the same time of day?
At least one FDA label for a product containing Insulin (rDNA) says to take it with food. If you take Fulvic Acid on an empty stomach out of habit, keep them separate and take Insulin (rDNA) with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Insulin (rDNA) products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Fulvic Acid and Insulin (rDNA) combination checked?
Interactions in our licensed database are recorded against drug classes. Insulin (rDNA) is filed under 2 classifications, and Fulvic Acid has documented interactions with 3 drug classes — none of Insulin (rDNA)'s classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Fulvic Acid interact with any other medications?
Yes. Fulvic Acid has 257 documented drug interactions in our database — Insulin (rDNA) is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Insulin (rDNA) interact with any supplements?
Yes. Insulin (rDNA) has documented interactions with 242 supplements in our database — Fulvic Acid is not one of them. The Insulin (rDNA) interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Fulvic Acid monograph Uses, safety profile, and every drug interaction in one place Insulin Lispro Injection drug information The full plain-English guide to this medication Insulin (rDNA) supplement interactions Every supplement checked against Insulin (rDNA), ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Insulin (rDNA) and Fulvic Acid?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.