Drug & supplement interaction

Indigo Pulchra + Doxepin

Doxepin brand names: Sinequan, Doxepin, Zonalon.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Indigo Pulchra and Doxepin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Indigo Pulchra and Doxepin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Doxepin and Indigo Pulchra in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Indigo Pulchra safety at a glance

Indigo Pulchra overall Not established We cannot verify what this product is, so its safety is unknown.
Pregnancy Avoid With no safety data, avoid use during pregnancy.
Breastfeeding Avoid With no safety data, avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Doxepin and Indigo Pulchra? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Doxepin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Doxepin is filed under 10 classifications — including tricyclic antidepressants (tcas), antidepressant drugs, qt interval-prolonging drugs. Indigo Pulchra has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Doxepin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Indigo Pulchra Does Interact With Other Medications

Indigo Pulchra has 86 moderate known drug interactions in our database — Doxepin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Doxepin)
Taking anything else?

Check Another of Your Medications Against Indigo Pulchra

Covers the 2,830 medications we’ve checked against Indigo Pulchra. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Doxepin

This page covers Indigo Pulchra only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Doxepin page lists 186 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), American Hellebore (major), Arsenic (major) and Beer (major).

By severity: 15 major · 145 moderate · 26 minor.

From our pharmacist’s overview on the Doxepin page

“Doxepin is a sedating tricyclic prescribed for depression, anxiety, and often sleep itself, and the people taking it tend to shop the same shelf where the trouble sits. Of the 186 supplements on file, 78 deepen its drowsiness, with alcohol (beer and wine carry major, well-documented ratings) and kava the clearest examples, and I would…”

Reviewed by 2 · Jul 18, 2026

Open the Doxepin interaction page

One more smart check

Taking Indigo Pulchra as Part of a Dietary Supplement Product? Check It for Interactions

We hold 9 real supplement products containing Indigo Pulchra, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Indigo Pulchra. Even though Indigo Pulchra itself has no known interaction with Doxepin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Indigo Pulchra and Doxepin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Indigo Pulchra
Steady interest

#843 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Doxepin
Top half

#1,006 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Indigo Pulchra reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Indigo Pulchra and Doxepin records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Indigo Pulchra

What is Indigo Pulchra?

Indigo Pulchra is not a plant or supplement that we can find in any reliable scientific or herbal reference. Because we cannot confirm what it is, what it contains, or whether it is safe, we cannot responsibly describe its uses or dosing. If you have a product with this name, talk to a pharmacist before using it.

An interaction check asks whether these two react with each other — it does not ask whether Indigo Pulchra is a good idea for someone in your situation. Here is what our Indigo Pulchra record says about it on its own.

Indigo Pulchra: dosing

There is no established or recommended dose for Indigo Pulchra because it is not a recognized supplement. We cannot suggest any amount as safe.

From our Indigo Pulchra monograph — the full record covers uses, side effects and every documented interaction.

Read the full Indigo Pulchra monograph & all interactions
Medication

About Doxepin (Insomnia)

What Is Doxepin (Insomnia) Used For?

Brand names: Sinequan, Doxepin, Zonalon

This product is marketed to temporarily relieve occasional trouble sleeping when it's brought on by anxiety, restlessness, stress, or sensitivity to caffeine.

It is a homeopathic remedy — meaning its claims are based on traditional homeopathic practice, not accepted medical evidence, and it has not been evaluated by the FDA for effectiveness.

Most-Reported Side Effects for Doxepin

From FAERS, the FDA’s public side-effect reporting system (12,553 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Toxicity to various agents 988 reports
Completed suicide 828 reports
Fatigue 793 reports
Nausea 679 reports
Headache 642 reports
See full Doxepin (Insomnia) drug information
Keep checking

Other Drugs & Indigo Pulchra

Browse every other medication we’ve checked against Indigo Pulchra — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Indigo Pulchra page.

No interaction 2,743 drugs checked — show the list

We also checked Indigo Pulchra against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Indigo Pulchra list.

See the full Indigo Pulchra interactions page
See every supplement checked against Doxepin, ranked by severity
Evidence & sources

Indigo Pulchra References

The 2 references that drive our Indigo Pulchra monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Tanko Y, Abdelaziz MM, Adelaiye AB, Fatihu MY, Musa KY. Effects of Hydromethanolic leaves extract of Indigofera pulchra on blood glucose levels of normoglycemic and alloxan-induced diabetic Wistar rats. International Journal of Applied Research in Natural
  2. Tanko Y, Mabrouk MA, Adelaiye AB, Fatihu MY, and Musa KY. Anti-diabetic and some haematological effects of ethylacetate and n-butanol fractions of Indigofera pulchra extract on alloxan-induced diabetic Wistar rats. J Endocrinol Diabetes. 2011; 2(1): 1-7.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Indigo Pulchra and Doxepin Together: Common Questions

Is it safe to take Indigo Pulchra with Doxepin?
We do not list a known interaction between Indigo Pulchra and Doxepin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Indigo Pulchra and Doxepin combination checked?
Interactions in our licensed database are recorded against drug classes. Doxepin is filed under 10 classifications, and Indigo Pulchra has documented interactions with 1 drug class — none of Doxepin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Indigo Pulchra interact with any other medications?
Yes. Indigo Pulchra has 86 documented drug interactions in our database — Doxepin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Doxepin interact with any supplements?
Yes. Doxepin has documented interactions with 186 supplements in our database — Indigo Pulchra is not one of them. The Doxepin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Indigo Pulchra monograph Uses, safety profile, and every drug interaction in one place Doxepin (Insomnia) drug information The full plain-English guide to this medication Doxepin supplement interactions Every supplement checked against Doxepin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Doxepin and Indigo Pulchra?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.