Drug & supplement interaction

Rabdosia Rubescens + Valrubicin

Valrubicin brand name: Valstar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Rabdosia Rubescens and Valrubicin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Rabdosia Rubescens and Valrubicin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Valrubicin and Rabdosia Rubescens in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rabdosia Rubescens safety at a glance

Rabdosia Rubescens overall Use caution Human safety data are limited, so use carefully and under professional guidance.
Pregnancy Avoid Not enough safety information exists, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Valrubicin and Rabdosia Rubescens? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Valrubicin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Valrubicin is filed under 3 classifications — topoisomerase ii inhibitors, antitumor antibiotics, oral drugs. Rabdosia Rubescens has documented interactions with 3 drug classes — the most serious being cytochrome p450 3a4 (cyp3a4) substrates (moderate), p-glycoprotein substrates (moderate) and cytochrome p450 2c9 (cyp2c9) substrates (minor) — and none of Valrubicin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Rabdosia Rubescens Does Interact With Other Medications

Rabdosia Rubescens has 714 moderate, 69 minor known drug interactions in our database — Valrubicin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 714 Minor 69 No known interaction 2,047 (incl. Valrubicin)
Taking anything else?

Check Another of Your Medications Against Rabdosia Rubescens

Covers the 2,830 medications we’ve checked against Rabdosia Rubescens. Pick one to open its full report.

What to actually watch for

What Valrubicin’s Own FDA Label Lists

This is not an interaction — none of it involves Rabdosia Rubescens. These are the most notable effects listed in the ADVERSE REACTIONS section of Valrubicin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Pain or burning when passing urine Worth acting on
  • Trouble passing urine Worth acting on
  • High blood sugar Worth acting on
  • Chest pain Worth acting on
  • Anemia Worth acting on
  • A higher chance of infection Worth acting on
  • Loss of bladder control
  • Passing urine more often
  • Bloating or gas
  • Back pain

Showing the 10 most notable of 22 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Valrubicin. Read the label on DailyMed › Rabdosia Rubescens’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Rabdosia Rubescens side to compare — that is a limit of the record, not a statement that Rabdosia Rubescens has no side effects.

Everything else you take

See Every Supplement That Interacts With Valrubicin

This page covers Rabdosia Rubescens only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Valrubicin page lists 24 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coffee Charcoal (moderate) and European Mandrake (moderate).

By severity: 1 major · 14 moderate · 9 minor.

From our pharmacist’s overview on the Valrubicin page

“Activated charcoal is the supplement I would flag hardest for anyone receiving valrubicin (Valstar), a chemotherapy instilled directly into the bladder for cancer. It carries the only major rating among the 24 ingredients on this page, since charcoal can bind and clear many drugs from the body even when they are not swallowed.”

Reviewed by 2 · Jul 18, 2026

Open the Valrubicin interaction page

How much people look this up

Where Rabdosia Rubescens and Valrubicin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rabdosia Rubescens
Steady interest

#983 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Valrubicin
Steady interest

#2,214 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rabdosia Rubescens reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Rabdosia Rubescens and Valrubicin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rabdosia Rubescens

What is Rabdosia Rubescens?

Rabdosia Rubescens
  • Sore throat and respiratory complaints
  • Inflammation
  • Antimicrobial support
  • Digestive complaints
  • Traditional cancer support

Rabdosia rubescens is a Chinese herb traditionally used for sore throats, inflammation, and infections, and its compound oridonin has drawn lab interest for possible anticancer effects. However, strong human evidence is lacking for any use, and safety has not been well studied, so talk with your pharmacist or doctor before trying it.

Rabdosia rubescens · Lamiaceae · Aerial parts (leaves and stems) · Capsules, tablets, powders, teas, and liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Rabdosia Rubescens is a good idea for someone in your situation. Here is what our Rabdosia Rubescens record says about it on its own.

Rabdosia Rubescens: dosing

There is no well-established, standardized dose for Rabdosia rubescens. Studies have used different forms and amounts, so there is no agreed-upon safe and effective dose for any condition.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our Rabdosia Rubescens monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rabdosia Rubescens monograph & all interactions
Medication

About Valrubicin Intravesical

What Is Valrubicin Intravesical Used For?

Brand name: Valstar

Valrubicin Intravesical Solution is used to treat BCG-refractory carcinoma in situ (CIS) of the urinary bladder — meaning bladder cancer that has not responded to BCG immunotherapy. It is given directly into the bladder (intravesically) rather than taken by mouth or injected into the bloodstream.

This treatment is specifically for patients whose cancer has not responded to BCG and for whom having the bladder surgically removed (cystectomy) right away would carry unacceptable health risks.

Most-Reported Side Effects for Valrubicin

From FAERS, the FDA’s public side-effect reporting system (177 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Underdose 26 reports
Bladder instillation procedure 24 reports
Urge incontinence 20 reports
Bladder spasm 13 reports
Urinary incontinence 11 reports
See full Valrubicin Intravesical drug information
Keep checking

Other Drugs & Rabdosia Rubescens

Browse every other medication we’ve checked against Rabdosia Rubescens — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
714Moderate
69Minor
2,046No known interaction
714 Moderate 69 Minor 2,046 No interaction
Moderate

714 interactions

Showing 60 of 714 moderate interactions — see all 714 on the Rabdosia Rubescens page.

Minor

69 interactions

Showing 60 of 69 minor interactions — see all 69 on the Rabdosia Rubescens page.

No interaction 2,046 drugs checked — show the list

We also checked Rabdosia Rubescens against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,046 medications checked with no known interaction — see the full Rabdosia Rubescens list.

See the full Rabdosia Rubescens interactions page
See every supplement checked against Valrubicin, ranked by severity
Evidence & sources

Rabdosia Rubescens References

The 3 references that drive our Rabdosia Rubescens monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chen S, Liu J, Zhang H. Efficacy of rabdosia rubescens in the treatment of gingivitis. J Huazhong Univ Sci Technolog Med Sci. 2009;29(5):659-63. PubMed
  2. Zhang YW, Zheng XW, Liu YJ, et al. Effect of oridonin on cytochrome P450 expression and activities in HepaRG Cell. Pharmacology. 2018;101(5-6):246-254. PubMed
  3. Li F, Fan J, Wu Z, et al. Reversal effects of Rabdosia rubescens extract on multidrug resistance of MCF-7/Adr cells in vitro. Pharm Biol. 2013;51(9):1196-203.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rabdosia Rubescens and Valrubicin Together: Common Questions

Is it safe to take Rabdosia Rubescens with Valrubicin?
We do not list a known interaction between Rabdosia Rubescens and Valrubicin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Rabdosia Rubescens and Valrubicin combination checked?
Interactions in our licensed database are recorded against drug classes. Valrubicin is filed under 3 classifications, and Rabdosia Rubescens has documented interactions with 3 drug classes — none of Valrubicin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Rabdosia Rubescens interact with any other medications?
Yes. Rabdosia Rubescens has 783 documented drug interactions in our database — Valrubicin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Valrubicin interact with any supplements?
Yes. Valrubicin has documented interactions with 24 supplements in our database — Rabdosia Rubescens is not one of them. The Valrubicin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Rabdosia Rubescens monograph Uses, safety profile, and every drug interaction in one place Valrubicin Intravesical drug information The full plain-English guide to this medication Valrubicin supplement interactions Every supplement checked against Valrubicin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Valrubicin and Rabdosia Rubescens?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.