Drug & supplement interaction

Red Raspberry + Diltiazem

Diltiazem brand names: Cardizem, Cardizem SR, Diltiaz SR, Cardizem CD, Tiazac, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Red Raspberry and Diltiazem in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Red Raspberry and Diltiazem

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diltiazem and Red Raspberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Red Raspberry safety at a glance

Red Raspberry overall Use caution Generally well tolerated by most adults, but evidence on safety is limited.
Pregnancy Likely Safe When the fruit is used orally in amounts commonly found in foods. Read the full pregnancy detail
Breastfeeding Likely Safe When the fruit is used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of red raspberry leaf; a... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diltiazem and Red Raspberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Diltiazem

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diltiazem is filed under 9 classifications — including calcium channel blockers, cytochrome p450 1a2 (cyp1a2) inhibitors, cytochrome p450 3a4 (cyp3a4) inhibitors. Red Raspberry has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and insulin (moderate) — and none of Diltiazem’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Red Raspberry Does Interact With Other Medications

Red Raspberry has 135 moderate known drug interactions in our database — Diltiazem isn’t one of them. If you take anything else, check it against the full list below.

Moderate 135 No known interaction 2,695 (incl. Diltiazem)
Taking anything else?

Check Another of Your Medications Against Red Raspberry

Covers the 2,830 medications we’ve checked against Red Raspberry. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Red Raspberry and Diltiazem May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Shortness of breath Worth acting on reported in 9.6% of FDA reports for Diltiazem Additional detail

    Red Raspberry

    “A case of occupational asthma due to the inhalation of red raspberry powder has been reported for a 35-year-old female. Symptoms included wheezing and shortness of breath.”

    Red Raspberry · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 70370. Sherson, D., Andersen, B., Hansen, I., and Kjoller, H. Occupational asthma due to freeze-dried raspberry. Ann Allergy Asthma Immunol. 2003;90(6):660-663. PubMed

    Diltiazem

    Listed in the ADVERSE REACTIONS section of the FDA label for Diltiazem, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

  • Stomach upset / Diarrhea reported in 6.1% of FDA reports for Diltiazem Additional detail

    Red Raspberry

    “Orally, red raspberry may cause gastrointestinal upset, diarrhea, and epigastric pain.”

    Red Raspberry · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 112127. Henrotin Y, Cozannet RL, Fança-Berthon P, et al. Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial. BMC Musculoskelet Disord 2022;23(1):650. PubMed

    Diltiazem

    Listed in the ADVERSE REACTIONS section of the FDA label for Diltiazem, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Reported for Red Raspberry but not commonly for Diltiazem: wheezing.

Effects for Diltiazem come from the ADVERSE REACTIONS section of its FDA label; effects for Red Raspberry come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 34,400 voluntary FDA FAERS reports for Diltiazem that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Red Raspberry in Pregnancy & Breastfeeding

Pregnancy Likely Safe

When the fruit is used orally in amounts commonly found in foods.

Pregnancy Possibly Safe

When red raspberry leaf is used orally and appropriately in medicinal amounts during late pregnancy under the supervision of a healthcare provider. Red raspberry leaf is used by nurse midwives to facilitate delivery. There is some evidence that red raspberry leaf in doses of up to 2.4 grams daily, beginning at 32 weeks' gestation and continued until delivery, can be safely used for this purpose. Make sure patients do not use red raspberry leaf without the guidance of a healthcare professional.

Pregnancy Likely Unsafe

When red raspberry leaf is used orally in medicinal amounts throughout pregnancy or for self-treatment. Red raspberry leaf might have estrogenic effects. These effects can adversely affect pregnancy. Tell pregnant patients not to use red raspberry leaf at any time during pregnancy without the close supervision of a healthcare provider.

Lactation Likely Safe

When the fruit is used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of red raspberry leaf; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Diltiazem Is Prescribed For, and What Red Raspberry Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Diltiazem is a prescription medicine with approved uses on its FDA label. Red Raspberry is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Diltiazem is prescribed for: Oral extended-release forms of diltiazem — including Matzim LA, Cardizem LA, Cartia, Cartia XT, Tiadylt ER, and various generic capsules and tablets — are used to treat high blood pressure (hypertension) and chronic stable angina (chest pain brought on by activity). Some capsule formulations, including Cartia, Cartia XT, and certain generics, are also approved for angina due to coronary artery spasm (sudden chest pain caused by a sudden tightening of a coronary artery). Injectable forms of diltiazem are used in hospital settings to temporarily slow a dangerously fast heart rate in atrial fibrillation or atrial flutter (rapid, irregular heart rhythms), and to restore a normal heart rhythm in paroxysmal supraventricular tachycardia (PSVT) — sudden episodes of a very fast but regular heartbeat originating above the heart's lower chambers.

Red Raspberry has been studied for:

  • Hypertension studied, not established Red Raspberry has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Red Raspberry for hypertension

    Although there has been interest in using oral red raspberry leaf for hypertension, there is insufficient reliable information about the clinical effects of red raspberry for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Diltiazem on your own; if you are taking Red Raspberry for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Red Raspberry or Diltiazem

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Red Raspberry or Diltiazem, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Diltiazem

This page covers Red Raspberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diltiazem page lists 260 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Coleus (major) and Grapefruit (major).

By severity: 7 major · 214 moderate · 39 minor.

From our pharmacist’s overview on the Diltiazem page

“Someone on diltiazem (Cardizem, Tiazac) is usually managing blood pressure, angina, or a fast heart rhythm, so this list deserves genuine care. Seven of the 260 ingredients on file carry a major rating, and two of those are things people actually buy: grapefruit, which blocks the enzyme that clears diltiazem and can push its blood leve…”

Reviewed by 2 · Jul 18, 2026

Open the Diltiazem interaction page

One more smart check

Taking Red Raspberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,303 real supplement products containing Red Raspberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Red Raspberry. Even though Red Raspberry itself has no known interaction with Diltiazem, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Red Raspberry and Diltiazem Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Red Raspberry
Top 25%

#161 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diltiazem
Top 25%

#335 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Red Raspberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Red Raspberry and Diltiazem records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Red Raspberry

What is Red Raspberry?

  • Pregnancy and labor support
  • Menstrual cramps
  • Digestive upset and diarrhea
  • Sore throat and mouth rinse
  • Antioxidant support

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is generally considered well tolerated by most adults, but pregnant people should talk with their doctor or midwife before using it.

Rubus idaeus · Rosaceae · Leaves and fruit · Tea, capsules, tablets, dried leaf, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Red Raspberry is a good idea for someone in your situation. Here is what our Red Raspberry record says about it on its own.

Red Raspberry: dosing

There is no official or standardized dose for red raspberry leaf. It is most commonly taken as a tea made from dried leaves, and also comes in capsules, tablets, and liquid extracts.Because products vary in strength, the best approach is to follow the directions on the product label.

From our Red Raspberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Red Raspberry monograph & all interactions
Medication

About Diltiazem

What Is Diltiazem Used For?

Brand names: Cardizem, Cardizem SR, Diltiaz SR, Cardizem CD, Tiazac, Diltiaz XT, Diltiaz CD, Dilacor, Diltiaz, Cardizem LA, Dilacor XR, Cartia XT, Tiamate, Adizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Dilcardia SR, Dilzem SR, Dilzem XL, Slozem, Tildiem LA, Tildiem Retard, Viazem XL, Zemtard 120XL, Zemtard 180XL, Zemtard 240XL, Zemtard 300XL

Oral extended-release forms of diltiazem — including Matzim LA, Cardizem LA, Cartia, Cartia XT, Tiadylt ER, and various generic capsules and tablets — are used to treat high blood pressure (hypertension) and chronic stable angina (chest pain brought on by activity). Some capsule formulations, including Cartia, Cartia XT, and certain generics, are also approved for angina due to coronary artery spasm (sudden chest pain caused by a sudden tightening of a coronary artery).

Injectable forms of diltiazem are used in hospital settings to temporarily slow a dangerously fast heart rate in atrial fibrillation or atrial flutter (rapid, irregular heart rhythms), and to restore a normal heart rhythm in paroxysmal supraventricular tachycardia (PSVT) — sudden episodes of a very fast but regular heartbeat originating above the heart's lower chambers.

Most-Reported Side Effects for Diltiazem

From FAERS, the FDA’s public side-effect reporting system (34,400 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 3,309 reports
Fatigue 2,733 reports
Nausea 2,454 reports
Dizziness 2,174 reports
Diarrhea 2,113 reports
See full Diltiazem drug information
Keep checking

Other Drugs & Red Raspberry

Browse every other medication we’ve checked against Red Raspberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
135Moderate
0Minor
2,694No known interaction
135 Moderate 2,694 No interaction
Moderate

135 interactions

Showing 60 of 135 moderate interactions — see all 135 on the Red Raspberry page.

No interaction 2,694 drugs checked — show the list

We also checked Red Raspberry against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,694 medications checked with no known interaction — see the full Red Raspberry list.

See the full Red Raspberry interactions page
See every supplement checked against Diltiazem, ranked by severity
Evidence & sources

Red Raspberry References

The 8 references that drive our Red Raspberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  2. Parsons M, Simpson M, Ponton T. Raspberry leaf and its effects on labour: safety and efficacy. Aust Coll Midwives Inc J 1999;12:20-5.
  3. Simpson M, Parsons M, Greenwood J, Wade K. Raspberry leaf in pregnancy: its safety and efficacy in labor. J Midwifery Womens Health 2001;46:51-9.. PubMed
  4. Mullen W, McGinn J, Lean ME, et al. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J Agric Food Chem 2002;50:5191-6.. PubMed
  5. Sherson, D., Andersen, B., Hansen, I., and Kjoller, H. Occupational asthma due to freeze-dried raspberry. Ann Allergy Asthma Immunol. 2003;90(6):660-663. PubMed
  6. Cheang KI, Nguyen TT, Karjane NW, Salley KE. Raspberry Leaf and Hypoglycemia in Gestational Diabetes Mellitus. Obstet Gynecol. 2016;128(6):1421-4. PubMed
  7. Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.
  8. Henrotin Y, Cozannet RL, Fança-Berthon P, et al. Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial. BMC Musculoskelet Disord 2022;23(1):650. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Red Raspberry and Diltiazem Together: Common Questions

Is it safe to take Red Raspberry with Diltiazem?
We do not list a known interaction between Red Raspberry and Diltiazem. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Red Raspberry and Diltiazem have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Red Raspberry and Diltiazem used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Red Raspberry in each. That is a conversation for your prescriber, especially if Diltiazem is being adjusted to a target.
How was the Red Raspberry and Diltiazem combination checked?
Interactions in our licensed database are recorded against drug classes. Diltiazem is filed under 9 classifications, and Red Raspberry has documented interactions with 2 drug classes — none of Diltiazem's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Red Raspberry interact with any other medications?
Yes. Red Raspberry has 135 documented drug interactions in our database — Diltiazem is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Diltiazem interact with any supplements?
Yes. Diltiazem has documented interactions with 260 supplements in our database — Red Raspberry is not one of them. The Diltiazem interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Red Raspberry monograph Uses, safety profile, and every drug interaction in one place Diltiazem drug information The full plain-English guide to this medication Diltiazem supplement interactions Every supplement checked against Diltiazem, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 8 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diltiazem and Red Raspberry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.