Reishi Mushroom - Vfend (Voriconazole) Interaction
Herbal: Reishi Mushroom
Also Known As: Ganoderma lucidum, Basidiomycetes Mushroom, Champignon Reishi, Champignons Reishi, Ganoderma, Hongo Reishi, Ling Chih, Ling Zhi, Lingzh, Mannentake, Mushroom, Mushroom of Immortality, Red Reishi, Reishi, Reishi Antler Mushroom, Reishi Rouge, Rei-Shi, Spirit Plant
Drug: Voriconazole
Brand names:
Vfend
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Voriconazole and Reishi Mushroom. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Reishi Mushroom Overview
Reishi mushroom (Ganoderma lucidum) is a type of mushroom native to Asia. It is a relatively tough mushroom with a shiny, reddish-brown exterior and a bitter, woody taste.
Reishi mushroom is popular in traditional medicine, with a history of use dating back several thousand years. It is purported to have a number of health benefits, including the ability to boost the immune system, reduce inflammation, and improve overall well-being.
Voriconazole Overview
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Voriconazole is used in adults and children 2 years of age and older to treat serious fungal infections such as invasive aspergillosis (a fungal infection that begins in the lungs and spreads through the bloodstream to other organs), esophageal candidiasis (a yeast [a type of fungus] infection that may cause white patching in the mouth and throat), and candidemia (a fungal infection in the blood). It is also used to treat certain other fungal infections when other medications will not work for certain patients. Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection.
Reishi Mushroom - More Interactions
Reishi Mushroom interacts with 370 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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