Medication interaction hub

What Supplements Interact with Bendroflumethiazide, Potassium?

Bendroflumethiazide, Potassium brand names: Neo-NaClex-K, Centyl K. Every interaction below applies to the brands too.

127 Interactions 7 Major 103 Moderate 17 Minor
Curated & coded by · Clinical Pharmacist · Updated September 15, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Bendroflumethiazide, Potassium? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Bendroflumethiazide, Potassium against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Bendroflumethiazide with potassium (Neo-NaClex-K, Centyl K) is a water pill for blood pressure with built-in potassium replacement, and its interaction list warrants real care rather than a quick skim. Seven of the 127 supplement ingredients on file rate major, and they concentrate on two hazards: added kidney damage (Siberian cocklebur is the best documented) and electrolyte swings the drug already creates, from deeper potassium loss with herbs like yellow dock to dangerously high calcium with dolomite.

Most of the 103 moderate entries echo those themes. Seventy-three ingredients act as diuretics themselves and can compound fluid and electrolyte loss, twenty add sun sensitivity, and a cluster of fibers and charcoal products can keep an oral dose from absorbing, which is why activated charcoal rates major. Calcium and high-dose vitamin D matter too, since thiazides slow calcium leaving the body. Space absorbent products well apart from your dose, and run kidney-active herbs past your pharmacist first.

— , Clinical Pharmacist · July 18, 2026

Major 7 Moderate 103 Minor 17 No known interaction 1,325

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Bendroflumethiazide, Potassium: Top Interactions at a Glance

The most significant Bendroflumethiazide, Potassium supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 127 interacting ingredients — plus 1,325 more checked with no known interaction. See the complete ranked list.

Start here

The Major Interactions to Know About

The most clinically significant Bendroflumethiazide, Potassium + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Likely Siberian Cocklebur + Bendroflumethiazide, Potassiumi

Siberian cocklebur can adversely affect the kidney.

Read the full interaction Major Likelihood Probable Activated Charcoal + Bendroflumethiazide, Potassiumi

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Dolomite + Bendroflumethiazide, Potassiumi

Taking thiazides with dolomite might increase the risk of hypercalcemia and kidney failure.

Read the full interaction Major Likelihood Probable Lithium + Bendroflumethiazide, Potassiumi

Theoretically, taking lithium supplements with loop diuretics might increase lithium levels and adverse effects.

Read the full interaction Major Likelihood Probable Oleander + Bendroflumethiazide, Potassiumi

Theoretically, diuretic drugs may increase the risk of oleander toxicity.

Read the full interaction Major Likelihood Probable Yellow Dock + Bendroflumethiazide, Potassiumi

Theoretically, yellow dock might increase the risk of hypokalemia when taken with diuretics.

Read the full interaction
The complete list

Every Supplement Checked Against Bendroflumethiazide, Potassium

All 1,452 ingredients in our database, ranked by severity — 127 with a Bendroflumethiazide, Potassium interaction on file and 1,325 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Bendroflumethiazide, Potassium?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Cocoa with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using cocoa with diuretic drugs might increase the risk of hypokalemia.

Full Cocoa + Bendroflumethiazide, Potassium answer

Can you take Calcium with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.

Full Calcium + Bendroflumethiazide, Potassium answer

Can you take Dulse with Bendroflumethiazide, Potassium?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, dulse might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.

Full Dulse + Bendroflumethiazide, Potassium answer

Can you take Bishop's Weed with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Bishop's weed constituents seem to cause photosensitivity.

Full Bishop's Weed + Bendroflumethiazide, Potassium answer

Can you take Black Hellebore with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of potassium depleting diuretics and black hellebore can increase the risk of cardiac glycoside toxicity due...

Full Black Hellebore + Bendroflumethiazide, Potassium answer

Can you take Black Root with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassiu...

Full Black Root + Bendroflumethiazide, Potassium answer

Can you take Black Seed with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking black seed with diuretic drugs might increase potassium loss and the risk of hypokalemia.

Full Black Seed + Bendroflumethiazide, Potassium answer

Can you take Black Tea with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using black tea with diuretic drugs might increase the risk of hypokalemia.

Full Black Tea + Bendroflumethiazide, Potassium answer

Can you take Blue Flag with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Overuse of blue flag might compound diuretic-induced potassium loss.

Full Blue Flag + Bendroflumethiazide, Potassium answer

Can you take Butternut with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Butternut has stimulant laxative effects.

Full Butternut + Bendroflumethiazide, Potassium answer

Can you take Caffeine with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.

Full Caffeine + Bendroflumethiazide, Potassium answer

Can you take Calotropis with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of calotropis and potassium depleting diuretics can increase the risk of cardiac glycoside toxicity due to po...

Full Calotropis + Bendroflumethiazide, Potassium answer

Can you take Canadian Hemp with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Canadian hemp contains cardiac glycosides.

Full Canadian Hemp + Bendroflumethiazide, Potassium answer

Can you take Caraway with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, caraway might increase the risk of hypokalemia when used with diuretics that deplete potassium.

Full Caraway + Bendroflumethiazide, Potassium answer

Can you take Cascara Sagrada with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, cascara sagrada might increase the risk of hypokalemia when taken with diuretic drugs.

Full Cascara Sagrada + Bendroflumethiazide, Potassium answer

Can you take Castor Bean with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, castor oil might increase the risk of hypokalemia when taken with diuretic drugs.

Full Castor Bean + Bendroflumethiazide, Potassium answer

Can you take Cesium with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking cesium concomitantly with other drugs that deplete potassium, such as diuretics, may increase the risk of hypokalemia.

Full Cesium + Bendroflumethiazide, Potassium answer

Can you take Chanca Piedra with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chanca piedra with diuretics might increase diuresis.

Full Chanca Piedra + Bendroflumethiazide, Potassium answer

Can you take Chelation Therapy Products with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use of ethylenediamine tetraacetic acid (EDTA) and potassium-depleting diuretics might increase the risk for hypokalemia.

Full Chelation Therapy Products + Bendroflumethiazide, Potassium answer

Can you take Chlorella with Bendroflumethiazide, Potassium?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, chlorella might have additive effects with photosensitizing drugs.

Full Chlorella + Bendroflumethiazide, Potassium answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Bendroflumethiazide, Potassium is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Bendroflumethiazide, Potassium, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Bendroflumethiazide, Potassium sits in 6 interaction categories. Open any one to see what the group means:

Diuretic Drugs 73 ingredients

Medications that increase fluid loss. Supplements affecting fluid or electrolytes (like potassium) can interact with them.

73 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Potassium-Sparing Diuretics 8 ingredients

Medications that increase fluid loss. Supplements affecting fluid or electrolytes (like potassium) can interact with them.

8 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Thiazide Diuretics 5 ingredients

Medications that increase fluid loss. Supplements affecting fluid or electrolytes (like potassium) can interact with them.

5 of the supplement ingredients on this page reach Bendroflumethiazide, Potassium through this category.

Related: does Bendroflumethiazide, Potassium deplete any nutrients?

Bendroflumethiazide, Potassium has 12 reported nutrient associations in the research literature — see the Bendroflumethiazide, Potassium nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Bendroflumethiazide, Potassium

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Bendroflumethiazide, Potassium.

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Products that contain Bendroflumethiazide, Potassium-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Bendroflumethiazide, Potassium.

Zi Sheng Teapills by Plum Flower contains Siberian Cocklebur Cold Away by Health Concerns contains Siberian Cocklebur Sugar Coated Bi Yan Pian by Plum Flower contains Siberian Cocklebur Pe Min Kan Wan by Plum Flower contains Siberian Cocklebur
Pharmacist Counseling Corner

Bendroflumethiazide, Potassium & Supplements: Common Questions

What supplements interact with Bendroflumethiazide, Potassium?
Our database currently documents 127 ingredients with a known Bendroflumethiazide, Potassium interaction (7 major, 103 moderate, 17 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 127. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, Dolomite.
Which Bendroflumethiazide, Potassium supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur, Activated Charcoal, Dolomite, Lithium and Oleander, among others. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Bendroflumethiazide, Potassium?
Plenty of supplements coexist fine with Bendroflumethiazide, Potassium; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Neo-NaClex-K have the same supplement interactions as Bendroflumethiazide, Potassium?
Yes — Neo-NaClex-K, Centyl K all contain Bendroflumethiazide, Potassium, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Bendroflumethiazide, Potassium deplete any vitamins or nutrients?
It might — Bendroflumethiazide, Potassium has 12 reported nutrient-depletion associations in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Bendroflumethiazide, Potassium nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Bendroflumethiazide, Potassium and my other medications?
This page covers Bendroflumethiazide, Potassium against supplements and herbal ingredients. Checking Bendroflumethiazide, Potassium against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.