Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

BCAA+G 1000 Lemonade Flavor Ingredients & Drug Interactions

by MRM Metabolic Response Modifiers

BCAA+G 1000 Lemonade Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BCAA+G 1000 Lemonade Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BCAA+G 1000 Lemonade Flavor is a dietary supplement by MRM Metabolic Response Modifiers with 5 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers

Ask about any prescription or over-the-counter medication and we check it for interactions with BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains five active ingredients: four amino acids (L-glutamine, L-leucine, L-isoleucine, and L-valine) and vitamin B6. The branched-chain amino acids — leucine, isoleucine, and valine — are often used together to support muscle recovery and protein synthesis, while L-glutamine plays a role in immune and gut health.

Vitamin B6 is included to support amino acid metabolism. The product also contains inactive ingredients: natural and artificial flavors, citric acid, and sucralose for taste and stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle recovery, strength and athletic performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Critical illness (trauma), HIV/AIDS-related wasting, Muscular dystrophy, Postoperative recovery — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Muscular dystrophy.

L-glutamine is effective for sickle cell disease and possibly effective for recovery after surgery, trauma, and HIV/AIDS-related wasting. Vitamin B6 is effective for treating sideroblastic anemia (a blood disorder) and vitamin B6 deficiency itself, and likely effective for lowering high homocysteine levels — a heart-health marker.

It's also possibly effective for pregnancy-related nausea. The effectiveness of the branched-chain amino acids (leucine, isoleucine, valine) as a general supplement isn't established in the data we hold.

The evidence, ingredient by ingredient Glutamine Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated, though people with kidney or liver disease should only use it under medical supervision. Oral use can cause belching, bloating, constipation, diarrhea, flatulence, nausea, vomiting, headache, and gastrointestinal pain.

Rare cases of dizziness and mood changes (mania or hypomania) have been reported in people with bipolar disorder. Vitamin B6 is well tolerated at doses below 100 mg daily.

At high doses over time, it can cause nerve damage (sensory neuropathy), particularly at amounts over 1,000 mg daily. Common side effects include headache, nausea, heartburn, and loss of appetite.

In pregnancy, vitamin B6 is likely safe at recommended levels, often used for morning sickness under a doctor's care, but safety data in lactation is less certain.

Side effects, ingredient by ingredient Glutamine Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Glutamine, Vitamin B6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; Parkinson's medications.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check if you're on anticonvulsant medications like phenytoin or phenobarbital (Moderate severity with glutamine and vitamin B6), blood pressure medications (Moderate with vitamin B6), the heart rhythm drug amiodarone (Moderate with vitamin B6), or levodopa for Parkinson's (Minor with vitamin B6). We could not check interactions for the branched-chain amino acids themselves.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BCAA+G is a straightforward amino acid and vitamin supplement that may help muscle recovery and support glutamine-dependent health needs like sickle cell disease. If you take anticonvulsants, antihypertensive drugs, amiodarone, or levodopa, check with your pharmacist before starting — vitamin B6 and glutamine both have documented interactions with these drug types.

Otherwise, it's generally well tolerated in healthy adults.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BCAA+G 1000 Lemonade Flavor, straight from the product label.

Brand MRM Metabolic Response Modifiers
Net contents 2.2 lbs; 1000 g
Market status On market
Date entered into DSLD Oct 25, 2012
DSLD ID 12475
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Gram(s)
Maximum serving Sizes:
6 Gram(s)
Servings per container
166
IngredientAmount% DV
L-Glutamine1000 mg--
Vitamin B62 mg100%
L-Leucine2500 mg--
L-Isoleucine1000 mg--
L-Valine1500 mg--

Other ingredients: Branched-Chain Amino Acids, Natural & Artificial flavors, Citric Acid, Pyridoxine Hydrochloride, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

BCAA+G contains a precise, bioengineered ratio of Branched Chain Amino Acids (BCAAs) and L-Glutamine, which are clinically proven to be essential for building muscle size and strength.

BCAA+G(TM) is the Ultimate Muscle Recovery formula nutritionally engineered for today’s serious athlete. This powerful, anti-catabolic formula promotes lean muscle gains, faster recovery and explosive energy to enhance any training regimen.

THE ULTIMATE MUSCLE RECOVERY FORMULA ENHANCED WITH L-GLUTAMINE

General Statements

During intense training or dieting, free amino acid pools (in muscle tissue) decrease, drastically reducing protein synthesis (the ability to build muscle). Research has indicated that BCAAs and Glutamine supplementation support this free amino acid pool in the muscle tissue, increasing protein synthesis and allowing the body to build lean muscle mass. Because the body cannot manufacture its own BCAAs, their importance in the diet are vital for maximum muscle growth and recovery.

6 09492 71027 _ Lot #: Best if used by:

INCREASES NITROGEN RETENTION OPTIMIZES MUSCLE SIZE, STRENGTH & RECOVERY

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

HPLC TESTED FOR PURITY 100% Micronized

Formulation

ASPARTAME & SUGAR FREE

Contains NO dairy, egg, peanut, tree nut, fish, shellfish, soy, wheat, gluten or yeast.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: Take 3 scoops (2g scoop included) 2 times daily. 1 serving should be taken prior to exercise and 1 serving immediately following exercise. To maximize results, take this product with your favorite meal or supplement containing protein and carbohydrates (high glycemic) at a 1:3 ratio. PLEASE NOTE: BCAA+G(TM) does not mix well in water and must be shaken or swirled prior to each drink. It is normal for BCAA+G(TM) to float on top of the water. Also, BCAA+G(TM) can be consumed as powder directly into the mouth and chased with water.

Elite Training Athletes: To enhance muscle strength and recovery from intense training, it is recommended 0.17g of BCAA+G(TM) per lb of body weight per day. Best results are seen when entire daily portion is used before, during and immediately following training. For example, 180 lb person needs 0.17g x 180 lbs = 30g (or 15 scoops) BCAA+G(TM). Ideally, 10g BCAA+G(TM) prior to training, 10g BCAA+G™ during training and 10g BCAA+G(TM) after training.

Brand IP Statement(s)

BCAA+G(TM) increases protein synthesis, nitrogen retention and most importantly, protects hard earned muscle from the stress of heavy training and intense exercise. Clinical investigations have proven that the amino acids found in BCAA+G(TM) help the body recover quicker after intense training and promote lean muscle gains, while reducing unwanted body fat. Vitamin B6 has been added to enhance amino acid utilization directly into the muscle tissue.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BCAA+G 1000 Lemonade Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Gram(s) Dosage formPowder Servings per container166 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
1000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Vitamin B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

L-Leucine

2500 mg per serving

L-Isoleucine

1000 mg per serving

L-Valine

1500 mg per serving

Other (inactive) ingredients: Branched-Chain Amino Acids, Natural & Artificial flavors, Citric Acid, Pyridoxine Hydrochloride, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers Drug Interactions

Want to check YOUR meds against BCAA+G 1000 Lemonade Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
244 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
L-Glutamine 50

Individual Drug Interactions

The ingredients in BCAA+G 1000 Lemonade Flavor interact with 249 drugs. Click any drug to see the details.

2 of the 5 ingredients in BCAA+G 1000 Lemonade Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in BCAA+G 1000 Lemonade Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BCAA+G 1000 Lemonade Flavor, from the product label.

MRM Metabolic Response Modifiers

See all MRM Metabolic Response Modifiers products
Name
MRM
Street Address
2665 Vista Pacific Dr.
City
Oceanside
State
CA
ZipCode
92056
Phone Number
1-800-948-6296
Web Address
www.mrm-usa.com
Pharmacist Counseling Corner

BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers: Common Questions

Does BCAA+G 1000 Lemonade Flavor by MRM Metabolic Response Modifiers interact with any medications?
Yes. Based on its ingredients, BCAA+G 1000 Lemonade Flavor has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BCAA+G 1000 Lemonade Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy?
L-glutamine is likely safe in pregnancy. Vitamin B6 is also likely safe at recommended doses and is often used for morning sickness under a doctor's guidance. That said, safety data in lactation is less clear — talk with your doctor or pharmacist about whether this product is right for you during that time.
What are BCAAs and why are they in here?
BCAA stands for branched-chain amino acids — that's leucine, isoleucine, and valine. These are the three amino acids your body can't make and must get from food or supplements. They're included because they're thought to support muscle protein synthesis and recovery, especially after exercise or physical stress.
What side effects should I watch for?
The most common ones from glutamine are stomach upset — bloating, gas, diarrhea, nausea — and headache. Vitamin B6 at normal supplement levels is usually mild; watch for headache, nausea, or heartburn. At very high doses over time, B6 can cause nerve damage, but that's not a concern at the amounts in most supplements.
Can I take this if I have kidney or liver problems?
L-glutamine should only be used under medical supervision if you have kidney or liver disease. Talk with your doctor or pharmacist before starting this product.
Does this product have any fillers or artificial ingredients?
It contains natural and artificial flavors, citric acid, and sucralose for taste and preservation. If you're sensitive to artificial sweeteners or flavorings, you'll want to check the label details or reach out to the brand directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BCAA+G 1000 Lemonade Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BCAA+G 1000 Lemonade Flavor label
Go deeper

The Full Monographs Behind BCAA+G 1000 Lemonade Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

BCAA+G 1000 Lemonade Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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