Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

BCAA+G Green Apple Ingredients & Drug Interactions

by MRM

BCAA+G Green Apple label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BCAA+G Green Apple against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BCAA+G Green Apple is a dietary supplement by MRM with 5 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against BCAA+G Green Apple by MRM

Ask about any prescription or over-the-counter medication and we check it for interactions with BCAA+G Green Apple by MRM — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of BCAA+G Green Apple by MRM

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BCAA+G Green Apple delivers 5 active amino acids: L-Glutamine, L-Leucine, L-Isoleucine, L-Valine, and Vitamin B6. Leucine, isoleucine, and valine are branched-chain amino acids (BCAAs) that support muscle recovery and protein synthesis.

L-Glutamine helps maintain gut health and supports immune function, especially during recovery from illness or intense training. Vitamin B6 plays a role in amino acid metabolism and energy production.

The powder also contains inactive ingredients—natural green apple flavor, citric acid, stevia leaf extract, and monk fruit extract—for taste and stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle building, strength and recovery.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscular dystrophy, Postoperative recovery, Wound healing, Lean muscle gains — and 2 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for Postoperative recovery (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Muscular dystrophy.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Exercise-induced muscle damage.

L-Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma. Vitamin B6 is effective for sideroblastic anemia and vitamin B6 deficiency, and likely effective for high homocysteine levels.

The evidence for the three branched-chain amino acids in this product isn't established in the data we hold.

The evidence, ingredient by ingredient Glutamine Vitamin B6

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated but people with kidney or liver disease should use it only under medical supervision. Common side effects include belching, bloating, constipation, diarrhea, nausea, and vomiting, especially at high doses.

Rare neurological effects like dizziness and mood changes have been reported. Vitamin B6 is safe at standard supplement doses but high doses over time can damage nerves; doses exceeding 1,000 mg daily carry the most risk.

Common side effects are headache, nausea, and heartburn. For pregnancy, L-Glutamine is rated likely safe, and Vitamin B6 is likely safe in pregnancy but possibly unsafe at high doses; for breastfeeding, L-Glutamine has insufficient data, so avoid supplement doses unless your doctor advises otherwise, while Vitamin B6 is likely safe.

Side effects, ingredient by ingredient Glutamine Vitamin B6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Glutamine, Vitamin B6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; Parkinson's medications.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check these medication types with the search tool: anticonvulsants (seizure drugs like phenytoin and phenobarbital), antihypertensive drugs (blood pressure medications), amiodarone, and levodopa. High doses of Vitamin B6 in this product could reduce how well anticonvulsants and seizure medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BCAA+G works well for muscle recovery and amino acid support, especially if you're training or recovering from illness. If you take anticonvulsants, blood pressure medications, amiodarone, or levodopa, check your exact medications with the tool on this page before starting—Vitamin B6 at high doses may interfere with how they work.

Talk to your pharmacist if you have kidney or liver disease or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BCAA+G Green Apple, straight from the product label.

Brand MRM
Barcode (UPC) 60949271032
Net contents 0.396 lbs; 180 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2018
DSLD ID 178962
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BCAA+G Green Apple by MRM, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6.5 Gram(s)
Maximum serving Sizes:
6.5 Gram(s)
Servings per container
27
UPC/BARCODE
60949271032
IngredientAmount% DV
L-Glutamine1000 mg--
Vitamin B62 mg100%
L-Leucine2500 mg--
L-Isoleucine1000 mg--
L-Valine1500 mg--

Other ingredients: natural Green Apple flavor, Citric Acid, Stevia leaf extract, Monk Fruit extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

BCAA+G contains a precise, bioengineered ratio of Branched Chain Amino Acids (BCAAs) and L-Glutamine, which are clinically proven to be essential for building muscle size and strength.

Vitamin B6 has been added to enhance amino acid utilization directly into the muscle tissue.

BCAA+G is the ultimate muscle recovery formula nutritionally engineered for today's serious athlete.

Ultimate muscle recovery formula enhanced with L-Glutamine 100% micronized BCAA

Brand IP Statement(s)

BCAA+G increases protein synthesis, nitrogen retention and most importantly, protects hard earned muscle from the stress of heavy training and intense exercise. Clinical investigations have proven that the amino acids found in BCAA+G help the body recover quicker after intense training and promote lean muscle gains, while reducing unwanted body fat.

General Statements

During intense training or dieting, free amino acid pools (in muscle tissue) decrease, drastically reducing protein synthesis (the ability to build muscle). Research has indicated that BCAAs and Glutamine supplementation support this free amino acid pool in the muscle tissue, increasing protein synthesis and allowing the body to build lean muscle mass. Because the body cannot manufacture its own BCAAs, their importance in the diet are vital for maximum muscle growth and recovery.

This powerful, anti-catabolic formula promotes lean muscle gains, faster recovery and explosive energy to enhance any training regimen.

Fermented

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

1706V01

Seals/Symbols

Certified Vegan Vegan.org

GMP Produced in a certified facility Good Manufacturing Practices

Formulation

Certified Vegan Vegan.org

Contains no added milk, egg, soy, peanut, tree nut, fish, shellfish, wheat, gluten or yeast ingredients.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Usage: Take 3 scoops 2 times daily. 1 serving should be taken prior to exercise and 1 serving immediately following exercise. Please note: BCAA+G does not mix well in water and must be shaken or swirled prior to each drink. It is normal for BCAA+G to float on top of the water. Also, BCAA+G can be consumed as powder directly into the mouth and chased with water. Elite Training Athletes: To enhance muscle strength and recovery from intense training best results are seen when BCAA+G is used before, during and immediately following training. For example: 3 scoops prior to training, 3 scoops during training and 3 scoops after training.

Precautions

This product is manufactured in a facility that processes other products that contain milk, egg or soy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BCAA+G Green Apple by MRM label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BCAA+G Green Apple label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BCAA+G Green Apple by MRM

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size6.5 Gram(s) Dosage formPowder Servings per container27 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
1000 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Vitamin B6

Interacts with
210 drugs
2 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

L-Leucine

2500 mg per serving

L-Isoleucine

1000 mg per serving

L-Valine

1500 mg per serving

Other (inactive) ingredients: Natural Green Apple flavor, Citric Acid, Stevia leaf extract, Monk Fruit extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

BCAA+G Green Apple by MRM Drug Interactions

Want to check YOUR meds against BCAA+G Green Apple?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
244 Moderate 5 Minor

Ingredients driving the most interactions

Vitamin B6 210
L-Glutamine 50

Individual Drug Interactions

The ingredients in BCAA+G Green Apple interact with 249 drugs. Click any drug to see the details.

2 of the 5 ingredients in BCAA+G Green Apple interact with drugs. Each result below shows which ingredient is responsible. Vitamin B6 L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in BCAA+G Green Apple with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BCAA+G Green Apple, from the product label.

MRM

See all MRM products
Name
MRM
Street Address
2665 Vista Pacific Dr.
City
Oceanside
State
CA
ZipCode
92056
Phone Number
1-800-948-6296
Web Address
www.mrm-usa.com
Pharmacist Counseling Corner

BCAA+G Green Apple by MRM: Common Questions

Does BCAA+G Green Apple by MRM interact with any medications?
Yes. Based on its ingredients, BCAA+G Green Apple has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BCAA+G Green Apple contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are BCAAs and why are they in this product?
Leucine, isoleucine, and valine are branched-chain amino acids (BCAAs) that your muscles use to recover and grow after exercise or physical stress. They're included here alongside glutamine to support overall amino acid availability during recovery.
Is this safe if I'm pregnant or breastfeeding?
L-Glutamine is rated likely safe in pregnancy, and Vitamin B6 is likely safe too—though B6 can be possibly unsafe at high doses in pregnancy. If you're breastfeeding, there isn't enough safety data on L-Glutamine, so talk to your doctor or pharmacist before using this product. It's an individual decision based on your situation.
What side effects might I notice?
The most common are gastrointestinal—bloating, gas, nausea, constipation, or diarrhea, especially at higher doses. Headache is also possible. If you take high doses over time, nerve damage from the Vitamin B6 is a rare but real risk, so stick to the label dose.
Do I need to worry about kidney or liver disease?
If you have kidney or liver disease, L-Glutamine should only be used under medical supervision. Talk to your doctor before starting this product.
Can I take this with my seizure or blood pressure medication?
Vitamin B6 in this product may interact with anticonvulsants, blood pressure drugs, and other medications. Use the medication checker on this page with your exact drug names, or ask your pharmacist before you start.
Is this product safe to use long-term?
L-Glutamine is generally well tolerated over time in healthy adults. Vitamin B6 is safe at the levels in standard supplements, but very high doses taken for long periods can harm nerves. As long as you follow the label dose and don't add extra B6 from other supplements, you should be fine—but talk to your pharmacist if you're taking this regularly alongside other medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BCAA+G Green Apple is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BCAA+G Green Apple label
Go deeper

The Full Monographs Behind BCAA+G Green Apple’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Sources

Sources & How We Checked

BCAA+G Green Apple's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 43 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
  16. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  17. Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
  18. Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
  19. Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
  20. de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
  21. Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
  22. Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
  23. Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
  24. Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
  25. Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
  26. Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
  27. Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
  28. Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
  29. Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
  30. Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
  31. Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
  32. Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed

See these in context on the Vitamin B6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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