Bilberry Myrtille Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Bilberry Myrtille against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bilberry Myrtille is a dietary supplement by Herbal Select with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 275 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bilberry Myrtille by Herbal Select
Ask about any prescription or over-the-counter medication and we check it for interactions with Bilberry Myrtille by Herbal Select — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bilberry Myrtille by Herbal Select
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: bilberry fruit extract. Bilberry is a small dark berry rich in anthocyanidins, plant compounds that give it antioxidant properties and have been studied for effects on vision, blood sugar, and blood clotting.
The capsule also contains inactive ingredients — gelatin, rice flour, and water — that serve as the capsule shell and filler.
Does it work?
Couldn't assess
The evidence for bilberry's effectiveness is mixed and often limited. For night vision, the data shows it is possibly ineffective — meaning current research does not support its use for this purpose.
For age-related cognitive decline, age-related macular degeneration (AMD), atherosclerosis, high cholesterol (hyperlipidemia), and chronic venous insufficiency (difficulty with blood return from the legs), we have insufficient reliable evidence to rate whether it works. This means the research so far has been too small, short, or low-quality to draw firm conclusions.
How safe is it?
Well-documented data
Bilberry fruit, juice, and extracts are generally well tolerated when taken orally. The most common side effects are dark-colored stools, gas, and mild stomach discomfort — some trial participants also reported temporary gastrointestinal upset.
Your tongue, teeth, or stools may turn dark bluish-black or dark green; this is harmless but can be striking. However, supplement-strength safety data is limited and long-term studies are sparse.
The safety notes advise against concentrated supplements because we don't have enough long-term safety information on those doses. Bilberry is rated likely safe in pregnancy and lactation.
Meds to double-check
Moderate interaction found
Before taking Bilberry Myrtille, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (such as warfarin, aspirin, or clopidogrel) — bilberry may raise bleeding risk. Also confirm if you take diabetes medications, since bilberry may lower blood sugar.
If you're on erlotinib (Tarceva) or other drugs metabolized through the CYP2E1 pathway, mention this supplement to your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Bilberry Myrtille is one to check if you take blood thinners, diabetes medications, or cancer drugs like erlotinib — the interactions are documented and worth reviewing with your doctor or pharmacist before you start. The evidence that it actually works for vision or cognition is weak or absent.
If you choose to use it, expect dark stools and possible gas, and avoid it if you're on medications that affect bleeding or blood sugar without clearance from your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bilberry Myrtille, straight from the product label.
| Brand | Herbal Select |
|---|---|
| Barcode (UPC) | 065279030035 |
| Net contents | 60 Capsule(s); 40 mg |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2013 |
| DSLD ID | 17659 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bilberry Myrtille by Herbal Select, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
General Statements
extract Potent-Max
Herbal Select use only guaranteed potency, standardized extracts or high potency natural concentrates and isolates to manufacture our potent-max extracts. This ensures that you get considered, effective results every time.
Standardized
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules 2-3 times daily with water.
Formulation
This product contains no added preservatives, colour, flavour, sugar, dairy, egg, wheat, soy, corn, starch or yeast.
Precautions
Do not use if seal is broken.
FDA Statement of Identity
A Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bilberry Myrtille by Herbal Select label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bilberry Myrtille by Herbal Select
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Bilberry
Interacts with275 drugs
Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...
Bilberry monograph & interactionsOther (inactive) ingredients: Gelatin, Rice Flour, Water. These complete the product’s ingredient list but are not active constituents.
Bilberry Myrtille by Herbal Select Drug Interactions
HelloPharmacist Interaction Report
Bilberry Myrtille by Herbal Select contains bilberry fruit extract, which has documented interactions with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (such as warfarin, aspirin, or clopidogrel) — bilberry may increase bleeding risk by inhibiting how your platelets clump together. This is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
You should also be cautious if you take diabetes medications. Bilberry extract may lower blood sugar, which could compound the effect of your antidiabetes drug and raise the risk of low blood sugar (hypoglycemia).
Additionally, bilberry may affect how your liver breaks down certain drugs processed through the CYP2E1 enzyme pathway, potentially lowering their levels in your bloodstream. There's also a theoretical concern with erlotinib (Tarceva), a cancer drug — bilberry may reduce its effectiveness.
All three of these interactions are rated Moderate.
Altogether, these interactions span 275 individual medications. Because the ingredient we checked does have documented interactions, use the medication search tool on this page to verify your specific drugs before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bilberry Myrtille?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bilberry Myrtille interact with 275 drugs. Click any drug to see the details.
1 of the 1 ingredient in Bilberry Myrtille interact with drugs. Each result below shows which ingredient is responsible. Bilberry
AbciximabReoPro
How Abciximab interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Bilberry + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAnticoagulant/antiplatelet Drugs, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryAnticoagulant/antiplatelet Drugs, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Bilberry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Bilberry Myrtille — through 1 ingredient. Tap an ingredient for the detail:
BilberryCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Read the full Bilberry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bilberry Myrtille with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bilberry
Anticoagulant/Antiplatelet Drugs
Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.
Erlotinib (Tarceva)
Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Bilberry Myrtille, from the product label.
Herbal Select
See all Herbal Select products- Name
- Herbal Select
- Street Address
- Unit 2 - 355 Michener Road
- City
- Guelph
- State
- Ont.
- ZipCode
- N1K 1E8
- Phone Number
- 1-888-313-3369
- Web Address
- www.herbalselect.com
Bilberry Myrtille by Herbal Select: Common Questions
Does Bilberry Myrtille by Herbal Select interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does bilberry actually help with vision?
What are the side effects?
Is it safe to take while pregnant or breastfeeding?
What is bilberry and what is it supposed to do?
How much bilberry is in each capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bilberry Myrtille is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bilberry Myrtille’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bilberry Myrtille's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bilberry 14 references
- Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
- Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
- Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
- Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
- Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
- Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
- Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
- Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
- Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
- Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
- Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
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