Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Blue Flag Root Ingredients & Drug Interactions

by TerraVita

Blue Flag Root label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blue Flag Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Blue Flag Root is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, constipation and digestive complaints, liver and gallbladder support (traditional).Based on those ingredients, 78 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Blue Flag Root Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blue Flag Root by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Blue Flag Root by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blue Flag Root by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blue flag root as a glycerite liquid extract. Blue flag root is prepared in glycerin, a sweet compound that acts as both a preservative and a base.

The extract is the whole ingredient doing the work here — there are no additional active components.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Blue Flag product and its label doesn't state a use — see Blue Flag's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold does not include effectiveness ratings for blue flag root, so we cannot tell you whether it works for any particular condition. Talk with your pharmacist or doctor about whether there's evidence for how you're thinking of using it.

The evidence, ingredient by ingredient Blue Flag

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue flag root can cause nausea, vomiting, and irritation of the mouth and throat, especially when the root is fresh. The volatile oils in blue flag can also irritate mucous membranes and may trigger headache, eye inflammation, or throat irritation.

The safety data advises against use during pregnancy due to potential toxicity and lack of safety information. Breastfeeding is also not recommended — there isn't enough data to know it's safe.

Side effects, ingredient by ingredient Blue Flag

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blue Flag.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 78 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your pharmacist if you're on digoxin (Lanoxin) for your heart — overuse poses a serious risk. Also flag it if you take diuretics (water pills) or warfarin (Coumadin), since blue flag can interfere with how they work and increase side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Blue flag Root is best for people who are not pregnant, not breastfeeding, and not taking digoxin, diuretics, or warfarin. If you're on any heart or blood-pressure medication, or any blood thinner, check with your pharmacist before you start.

Watch for nausea, vomiting, or throat irritation — these are signs the dose may be too high.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blue Flag Root, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435221577
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 280114
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blue Flag Root by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435221577
IngredientAmount% DV
Blue Flag Root Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blue Flag Root by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blue Flag Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blue Flag Root by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Blue Flag Root Glycerite Liquid Extract

Interacts with
78 drugs
0.13 mL per serving

Blue Flag is a flowering plant whose root has been used in traditional and herbal medicine for skin and digestive complaints, but there is very little...

Blue Flag Root Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blue Flag Root by TerraVita Drug Interactions

Want to check YOUR meds against Blue Flag Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
78Drugs
1 Major 77 Moderate

Ingredients driving the most interactions

Blue Flag Root Glycerite Liquid Extract 78

Individual Drug Interactions

The ingredients in Blue Flag Root interact with 78 drugs. Click any drug to see the details.

1 of the 1 ingredient in Blue Flag Root interact with drugs. Each result below shows which ingredient is responsible. Blue Flag Root Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Blue Flag Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blue Flag Root Glycerite Liquid Extract3 drug types · 78 drugs

Digoxin (Lanoxin)

Theoretically, overuse or abuse of this product increases the risk of adverse effects from cardiac glycoside drugs.

Likelihood Probable Evidence D
Diuretic Drugs

Overuse of blue flag might compound diuretic-induced potassium loss. There is some concern that people taking blue flag along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Blue flag has stimulant laxative effects. In some people blue flag can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of blue flag.

Likelihood Possible Evidence D
Blue Flag Root Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blue Flag Root, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Blue Flag Root by TerraVita: Common Questions

Does Blue Flag Root by TerraVita interact with any medications?
Yes. Based on its ingredients, Blue Flag Root has a known interaction with 78 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blue Flag Root contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take blue flag root while I'm pregnant?
No. The safety data advises against it because of potential toxicity and lack of safety information. Talk with your doctor or midwife before using any supplement during pregnancy.
Is it safe to breastfeed while taking this?
No. There isn't enough data to know it's safe while breastfeeding, so it's best to avoid it. If you're interested in blue flag for a particular reason, ask your pharmacist or doctor about alternatives.
What side effects should I watch for?
Nausea, vomiting, and irritation of your mouth and throat are the main ones. You might also get a headache or irritation of your eyes or throat. These are more likely with the fresh root or if you take too much. If they happen, lower your dose or stop and talk to your pharmacist.
What is blue flag root supposed to do?
We don't have effectiveness information on file for this ingredient, so we can't tell you what conditions it's meant to treat. Ask your pharmacist what evidence exists for the reason you're considering it.
Is there anything else in this product besides blue flag?
The liquid extract is mixed with glycerin, which preserves it and gives it a sweet taste. Glycerin is an inactive ingredient — the active component is the blue flag root itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blue Flag Root is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blue Flag Root label
Go deeper

The Full Monographs Behind Blue Flag Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blue Flag

Interacts with 78 drugs

Blue Flag is a flowering plant whose root has been used in traditional and herbal medicine for skin and digestive complaints, but there is very little modern scientific evidence to support t...

Read the full Blue Flag monograph →
Sources

Sources & How We Checked

Blue Flag Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue Flag 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Blue Flag monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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