Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Brain Ingredients & Drug Interactions

by Daily Sprays

Brain label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Brain against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Brain is a dietary supplement by Daily Sprays with 3 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 136 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Brain by Daily Sprays

Ask about any prescription or over-the-counter medication and we check it for interactions with Brain by Daily Sprays — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Brain by Daily Sprays

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Daily Sprays Brain contains 3 active ingredients. L-Glutamine is an amino acid your body uses for immune function and muscle repair, especially after stress or surgery.

Inositol is a carbohydrate-like compound involved in blood sugar and cell signaling. Vitamin B1 (thiamine) is an essential vitamin that helps your cells convert food into energy.

The product also contains inactive ingredients — purified water, glycerin, cane sugar, strawberry flavor, stevia leaf extract, and potassium sorbate — as a liquid spray formulation.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Brain health.
  • We looked for evidence on: Anxiety, Attention deficit-hyperactivity disorder (ADHD), Bipolar disorder, Depression, Insomnia, Obsessive-compulsive disorder (OCD) — and 4 related terms.
  • The closest evidence on file: Inositol is rated "Possibly Ineffective" for Anxiety (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Depression.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Bipolar disorder, Insomnia, Obsessive-compulsive disorder (OCD), Panic disorder, and more.

The evidence for these ingredients is mixed and depends on what you're using it for. L-Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome, and possibly effective for preterm labor, but the evidence suggests it's not effective for anxiety, diabetic nerve pain, or depression. We don't have effectiveness data on file for Vitamin B1 in this product's context.

The evidence, ingredient by ingredient Glutamine Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine and Inositol are generally well tolerated in most people. The most common side effects are digestive: belching, bloating, diarrhea, gas, constipation, nausea, and gastrointestinal pain.

A small number of trial participants taking high doses reported headache or dizziness, though one person's dizziness went away when the dose was lowered. If you have kidney or liver disease, L-Glutamine should only be used under a doctor's supervision.

For pregnancy and breastfeeding, L-Glutamine is rated likely safe, but Inositol has not been fully studied in pregnancy and lactation — talk to your doctor or pharmacist before use if you're pregnant or nursing. We hold no safety data on file for Vitamin B1 in this product.

Side effects, ingredient by ingredient Glutamine Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Inositol, Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; diabetes medications.
  • For scale: 136 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take anticonvulsants (seizure drugs) — L-Glutamine might reduce how well they work. Also check with us if you're on antidiabetes medications, since Inositol can lower blood sugar and raise the risk of low blood sugar episodes.

No interactions are documented for Vitamin B1 based on the data we hold.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product might help with sickle cell disease or recovery from surgery or illness, but the evidence for other uses is weak or absent. If you take seizure medications or diabetes drugs, check with us first — the L-Glutamine and Inositol here could interfere.

People with kidney or liver problems should get their doctor's okay. Talk to your pharmacist about whether it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Brain, straight from the product label.

Brand Daily Sprays
Net contents 0.47 Ounce(s); 14 mL
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 247561
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Brain by Daily Sprays, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.47 mL
Maximum serving Sizes:
0.47 mL
Servings per container
30
IngredientAmount% DV
L-Glutamine5 mg--
Inositol10 mg--
Vitamin B15 mg420%

Other ingredients: purified Water, Glycerin, Cane Sugar, Strawberry flavor, Stevia leaf extract, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Assembled in China in a cGMP Facility

Brain health

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Shake well before use. Spray directly into mouth and hold 5 seconds before swallowing. Take 1 serving (8 sprays) daily.

Precautions

Caution: Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Consult your physician prior to use.

Storage

Store in a cool, dry place.

General Statements

mydailychoice

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Brain by Daily Sprays label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Brain label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Brain by Daily Sprays

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.47 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
5 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Inositol

Interacts with
86 drugs
10 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Vitamin B1

5 mg per serving

Other (inactive) ingredients: Purified Water, Glycerin, Cane Sugar, Strawberry flavor, Stevia leaf extract, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Brain by Daily Sprays Drug Interactions

Want to check YOUR meds against Brain?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
136Drugs
136 Moderate

Ingredients driving the most interactions

Inositol 86
L-Glutamine 50

Individual Drug Interactions

The ingredients in Brain interact with 136 drugs. Click any drug to see the details.

2 of the 3 ingredients in Brain interact with drugs. Each result below shows which ingredient is responsible. Inositol L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Brain with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Brain, from the product label.

Daily Sprays

See all Daily Sprays products
Name
MyDailyChoice, Inc.
Street Address
8840 West Russell Road, Suite 245
City
Las Vegas
State
NV
ZipCode
89148
Pharmacist Counseling Corner

Brain by Daily Sprays: Common Questions

Does Brain by Daily Sprays interact with any medications?
Yes. Based on its ingredients, Brain has a known interaction with 136 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Brain contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
L-Glutamine is rated likely safe in pregnancy, but Inositol hasn't been fully studied yet and you'd use it only under medical supervision. There's no safety data on file for Vitamin B1 in this product. Talk to your doctor or pharmacist before starting — it's an individual decision based on your health.
What are the most common side effects?
Digestive issues are most likely: diarrhea, gas, bloating, nausea, constipation, and stomach pain. These tend to be mild. Headache and dizziness have been reported in some people, especially at higher doses.
Is this spray really effective for brain health?
We don't have effectiveness data in our facts showing that L-Glutamine, Inositol, or Vitamin B1 at these doses improve general brain health or cognition. L-Glutamine does have evidence for sickle cell disease and recovery from surgery or critical illness, and Inositol has some evidence for PCOS and metabolic syndrome — but that's different from 'brain health.'
Can I take this with my seizure medication?
Not without checking first. L-Glutamine might theoretically work against anticonvulsants. Run your specific medication through the interaction checker on this page, or ask your pharmacist before you start.
What is L-Glutamine for?
It's an amino acid your body uses for immune function and muscle repair, especially after stress, surgery, or serious illness. The evidence is strongest for sickle cell disease and HIV/AIDS-related wasting.
Can I use this if I have kidney or liver disease?
L-Glutamine in this product should only be used under medical supervision if you have kidney or liver disease. Talk to your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Brain label
Go deeper

The Full Monographs Behind Brain’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Brain's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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