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Dietary supplement

CanLaze Ingredients & Drug Interactions

by Wholly Liquid

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

CanLaze is a dietary supplement by Wholly Liquid with 2 active ingredients. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pau d'Arco Extract, Wormwood Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of CanLaze by Wholly Liquid

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

CanLaze is a 2-ingredient liquid supplement. It contains Wormwood Extract and Pau d'Arco Extract, both traditional botanicals used in herbal medicine.

The remaining ingredients—purified water, vegetable glycerin, citric acid, sorbic acid, and potassium salt—are inactive ingredients that serve as the base, preservative, and pH buffer for the liquid formulation.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for both active ingredients in this product is not well established. Wormwood Extract has insufficient reliable evidence for biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis.

Pau d'Arco Extract likewise shows insufficient reliable evidence for cancer, peptic ulcers, wound healing, and dysmenorrhea. If you're considering this product for a specific health concern, talk with your pharmacist or doctor about whether stronger evidence exists for other options.

The evidence, ingredient by ingredient Wormwood Pau D'arco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood Extract carries real safety concerns. It contains thujone, a neurotoxin that can cause muscle aches, nausea, and vomiting even in typical medicinal amounts; at higher doses or with chronic use, it's linked to kidney damage, muscle breakdown, seizures, and serious neurological effects including hallucinations, tremors, and brain damage.

Pau d'Arco Extract is generally well tolerated at lower doses, but its active compound lapachol can cause anemia, bleeding risk, and severe nausea or diarrhea when doses exceed 1.5 grams daily. Wormwood is unsafe during pregnancy—it may stimulate the uterus—and safety data is insufficient for breastfeeding.

Pau d'Arco should be avoided during pregnancy due to possible harm to the developing baby, and there isn't enough safety information for breastfeeding. Short-term use of properly prepared wormwood products may be acceptable, but human safety data for pau d'arco is limited.

Side effects, ingredient by ingredient Wormwood Pau D'arco

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Pau D'arco, Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take CanLaze, check your medications with the tool on this page if you take anticonvulsants (seizure medications)—wormwood may interfere with their effectiveness. Also check if you take blood thinners or antiplatelet drugs like warfarin or aspirin—pau d'arco may increase bleeding risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a niche herbal product with limited evidence for its intended uses and real safety trade-offs, especially around wormwood's thujone content. It's not a first-line choice for any of the conditions it may target.

If you take anticonvulsants or blood thinners, this product poses documented interaction risks and should not be used without explicit guidance from your pharmacist or doctor. Talk to us before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CanLaze, straight from the product label.

Brand Wholly Liquid
Barcode (UPC) WLCAZE30
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 272083
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CanLaze by Wholly Liquid, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Drop(s)
Maximum serving Sizes:
15 Drop(s)
Servings per container
30
UPC/BARCODE
WLCAZE30
IngredientAmount% DV
Wormwood Extract200 mg--
Pau d'Arco Extract200 mg--

Other ingredients: purified Water, Vegetable Glycerin, Citric Acid, Sorbic Acid, Potassium Salt

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take 5-15 drops in 1-2 oz. of water, three times per day on an empty stomach or as directed by your healthcare professional.

Storage

Storage Instructions: Store at room temperature away from direct sunlight. Keep tightly closed.

Precautions

Warning: Consult your healthcare professional before use if you are pregnant, nursing, taking medications, have a known medical condition, or for any use by minors.

Warning: Consult your healthcare professional before use if you are pregnant, nursing, taking medications, have a known medical condition, or for any use by minors.

Do not use if safety seal is broken or missing.

Keep out of reach of children.

For nutritional use only.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Made in USA

Supports the elimination of candida, molds & fungi

Soy free Dairy free Sugar free Gluten free

Vegan

Alcohol free Allergen free No artificial colors or sugars No synthetic fillers or binders

Brand IP Statement(s)

Supplements as good as food

FDA Statement of Identity

Dietary Supplement

See for yourself

CanLaze by Wholly Liquid label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in CanLaze by Wholly Liquid

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Wormwood Extract

Interacts with
50 drugs
200 mg per serving Form: Artemisia absinthium

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It...

Wormwood Extract monograph & interactions

Pau d'Arco Extract

Interacts with
122 drugs
200 mg per serving Form: Tabebuia impetiginosa Extract

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activit...

Pau d'Arco Extract monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, Citric Acid, Sorbic Acid, Potassium Salt. These complete the product’s ingredient list but are not active constituents.

Interaction report

CanLaze by Wholly Liquid Drug Interactions

Want to check YOUR meds against CanLaze?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
172Drugs
172 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in CanLaze with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Pau d'Arco Extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that pau d'arco reduces platelet aggregation and may interfere with vitamin K. One clinical study shows that taking the lapachol constituent of pau d'arco in doses above 1.5 grams daily increases the risk of bleeding. The effects of whole pau d'arco or pau d'arco extract in humans are unclear.

Likelihood Possible Evidence D

Wormwood Extract1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for CanLaze, from the product label.

Wholly Liquid

See all Wholly Liquid products
Name
Wholly Liquid Nutritional Supplements, LLC
City
Hampton
State
NH
ZipCode
03842
Web Address
www.whollyliquid.com
Pharmacist Counseling Corner

CanLaze by Wholly Liquid: Common Questions

Does CanLaze by Wholly Liquid interact with any medications?
Yes. Based on its ingredients, CanLaze has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CanLaze contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take CanLaze if I'm pregnant or breastfeeding?
No. Wormwood is unsafe in pregnancy because it may stimulate the uterus and harm the developing baby. Pau d'Arco should also be avoided during pregnancy due to possible harm. Neither ingredient has enough safety data for breastfeeding, so both should be avoided while nursing. Talk with your doctor or pharmacist before using any herbal product during pregnancy or lactation.
What does Wormwood Extract do?
Wormwood has been used traditionally for various digestive and liver conditions, but the evidence supporting its use for biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis is currently insufficient and unreliable.
What does Pau d'Arco Extract do?
Pau d'Arco is a traditional botanical, but the evidence for its use in cancer, peptic ulcers, wound healing, and dysmenorrhea is currently insufficient and unreliable.
What are the side effects of CanLaze?
Wormwood can cause nausea, vomiting, and muscle aches; at higher doses or with long-term use, it may cause kidney damage, muscle breakdown, and serious neurological effects like seizures and hallucinations. Pau d'Arco at high doses (above 1.5 grams daily) may cause anemia, bleeding, and severe nausea or diarrhea. This product should not be used in high doses or long-term without medical supervision.
Is CanLaze safe to use long-term?
No. Wormwood contains thujone, a neurotoxin, and is only considered acceptable for short-term use of properly prepared products. Pau d'Arco has limited human safety data. Long-term use of either ingredient carries real risks and should not be done without direct medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CanLaze label
Sources

Sources & How We Checked

CanLaze's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Pau D'arco 6 references
  1. Gómez Castellanos JR, Prieto JM, Heinrich M. Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity? J Ethnopharmacol 2009;121:1-13. PubMed
  2. Guerra, Mde O., Mazoni, A. S., Brandao, M. A., and Peters, V. M. Toxicology of Lapachol in rats: embryolethality. Braz.J Biol. 2001;61(1):171-174. PubMed
  3. Felicio, A. C., Chang, C. V., Brandao, M. A., Peters, V. M., and Guerra, Mde O. Fetal growth in rats treated with lapachol. Contraception 2002;66(4):289-293. PubMed
  4. Son, D. J., Lim, Y., Park, Y. H., Chang, S. K., Yun, Y. P., Hong, J. T., Takeoka, G. R., Lee, K. G., Lee, S. E., Kim, M. R., Kim, J. H., and Park, B. S. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular s
  5. Block JB, Serpick AA, Miller W, Wiernik PH. Early clinical studies with lapachol (NSC-11905). Cancer Chemother Rep 2. 1974;4(4):27-8.
  6. Algranti E, Mendonça EM, Ali SA, Kokron CM, Raile V. Occupational asthma caused by Ipe (Tabebuia spp) dust. J Investig Allergol Clin Immunol 2005;15(1):81-3.

See these in context on the Pau D'arco monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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