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Dietary supplement

Celadrin Ingredients & Drug Interactions

by Bluebonnet

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Celadrin is a dietary supplement by Bluebonnet with 1 active ingredient.Based on those ingredients, 387 medications have a known interaction with it, the most serious rated major. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Celadrin by Bluebonnet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Celadrin Fatty Acid Complex” is a proprietary blend — the label gives one combined amount (1,050 mg) without saying how much of each component you get.
  • “Proprietary Blend of Esterified Fatty Acid Carbons” is a proprietary blend — the label doesn't break down how much of each component you get.

Celadrin contains 6 active ingredients. The one we have interaction data for is vitamin A palmitate, a form of vitamin A.

The other five are fatty acid esters — cetyl myristoleate, cetyl myristate, cetyl laurate, cetyl palmitoleate, and cetyl oleate — which make up the Celadrin fatty acid complex and a proprietary blend. The product also contains inactive ingredients (gelatin capsule, glycerin, soy lecithin, salmon fish oil, and carob) that help deliver and stabilize the active ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Vitamin A's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote flexibility and healthy joint function.
  • We looked for evidence on: Osteoarthritis, Joint stiffness, Joint mobility, Cartilage health.
  • The closest evidence on file: Vitamin A is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis (Natural Medicines).

Vitamin A palmitate is effective for vitamin A deficiency. The evidence is possibly effective for oral leukoplakia (a precancerous mouth condition), aging skin, measles, ulcerative colitis, and a lung condition in premature infants called bronchopulmonary dysplasia.

We don't hold effectiveness data for the other active ingredients in this product.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A palmitate is generally well tolerated at recommended amounts, but high doses build up in your body and can turn toxic. Serious effects from very high doses are rare but can include liver damage, a dangerous increase in brain pressure, severe headaches, and in extreme cases, coma or death.

Chronic overuse causes vitamin A toxicity symptoms like fatigue, dry and peeling skin, hair loss, and brittle nails. Young children are more sensitive to toxicity from a single large dose than adults.

On pregnancy and breastfeeding, the data shows vitamin A at recommended amounts is likely safe, but high doses (especially the retinol form) are possibly unsafe because they may cause birth defects — talk with your doctor or pharmacist before taking this while pregnant or nursing.

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 388 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check it with any retinoid medications (acne treatments like tretinoin or isotretinoin) — the combination can cause dangerous vitamin A buildup. Also flag it if you take warfarin or other blood thinners, tetracycline antibiotics, or any drug that strains your liver.

The vitamin A in Celadrin interacts with all of these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Celadrin might be worth considering if you're looking for joint support and don't take retinoids, blood thinners like warfarin, tetracycline antibiotics, or medications that stress the liver. If you take any of those, or any prescription drug at all, check your medications with the tool on this page first.

Your pharmacist can tell you whether the vitamin A dose in this product is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Celadrin, straight from the product label.

Brand Bluebonnet
Barcode (UPC) 743715011298
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2018
DSLD ID 179229
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Celadrin by Bluebonnet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
60
UPC/BARCODE
743715011298
IngredientAmount% DV
Vitamin A Palmitate0 NP--
Cetyl Myristoleate0 NP--
Cetyl Myristate0 NP--
Cetyl Laurate0 NP--
Cetyl Palmitoleate0 NP--
Cetyl Oleate0 NP--
Celadrin Fatty Acid Complex1050 mg--
Proprietary Blend of Esterified Fatty Acid Carbons0 NP--

Other ingredients: Gelatin, Glycerin, Soy Lecithin, Salmon Fish Oil, Carob

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take three softgels daily or as directed by a healthcare practitioner.

Formula

Bluebonnet’s Celadrin Softgels contain a blend of esterified fatty acids, which may promote flexibility and healthy joint function.

Esterified Fatty Acid Complex

Celadrin

Contains: Fish (salmon), soybeans

General Statements

Available in easy-to-swallow softgels for maximum assimilation and absorption.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

1129C

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Gluten free

Precautions

Contains: Fish (salmon), soybeans

Formulation

Free of milk, egg, crustacean shellfish, tree nuts, peanuts and wheat. Also free of corn, yeast, gluten, barley, rice, sodium and sugar.

See for yourself

Celadrin by Bluebonnet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Celadrin by Bluebonnet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Celadrin Fatty Acid Complex

1050 mg per serving
  • › Proprietary Blend of Esterified Fatty Acid Carbons

Other (inactive) ingredients: Gelatin, Glycerin, Soy Lecithin, Salmon Fish Oil, Carob. These complete the product’s ingredient list but are not active constituents.

Interaction report

Celadrin by Bluebonnet Drug Interactions

Want to check YOUR meds against Celadrin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
387Drugs
9 Major 378 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Celadrin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Celadrin, from the product label.

Bluebonnet

Name
Bluebonnet Nutrition Corporation
Street Address
12915 Dairy Ashford
City
Sugar Land
State
TX
ZipCode
77478
Web Address
www.bluebonnetnutrition.com
Pharmacist Counseling Corner

Celadrin by Bluebonnet: Common Questions

Does Celadrin by Bluebonnet interact with any medications?
Yes. Based on its ingredients, Celadrin has a known interaction with 387 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Celadrin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is vitamin A in this product safe at the dose listed?
Vitamin A is generally well tolerated at recommended amounts. This product contains vitamin A palmitate, and as long as you stay within the recommended dose on the label, you should be fine — just don't exceed it, because high doses build up in your body and can become toxic.
Can I take this while pregnant or nursing?
At recommended supplement amounts, vitamin A is likely safe in pregnancy and while nursing. But high doses (especially as retinol) can cause birth defects. Since this product contains vitamin A palmitate, check the dose on the label and talk with your doctor or pharmacist before starting it — they can tell you whether it's the right choice for you right now.
What does vitamin A do in this product?
Vitamin A supports vision, skin health, and immune function. It's effective for treating vitamin A deficiency and has possibly effective evidence for aging skin, mouth lesions, measles, and some other conditions. The other active ingredients in Celadrin are fatty acid esters, but we don't have effectiveness data for those.
What are the other ingredients in Celadrin?
Besides vitamin A palmitate, Celadrin contains five fatty acid esters — cetyl myristoleate, cetyl myristate, cetyl laurate, cetyl palmitoleate, and cetyl oleate — which make up the Celadrin complex. The capsule itself is gelatin, and it also has glycerin, soy lecithin, salmon fish oil, and carob as inactive ingredients.
What side effects might I notice?
At recommended doses, vitamin A is generally well tolerated with minimal side effects. At very high doses, you might notice headache, dizziness, dry and peeling skin, rashes, hair loss, or brittle nails. Serious effects from high doses are rare and include liver damage and dangerous brain pressure — which is why you should never exceed the dose on the label.
Should I worry about the soy in this product?
The product contains soy lecithin as an inactive ingredient (an emulsifier that helps stabilize the formula). If you have a soy allergy, check with your pharmacist before taking it — the amount is typically very small, but it's worth confirming for your specific situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Celadrin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Celadrin label
Sources

Sources & How We Checked

Celadrin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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