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Dietary supplement

Choline Bitartrate Ingredients & Drug Interactions

by Pure Nootropics

Choline Bitartrate label
See full label image
Capsule Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Choline Bitartrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Choline Bitartrate is a dietary supplement by Pure Nootropics with 1 active ingredient. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Choline Bitartrate by Pure Nootropics

Ask about any prescription or over-the-counter medication and we check it for interactions with Choline Bitartrate by Pure Nootropics — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Choline Bitartrate by Pure Nootropics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Choline” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.

This product contains one active ingredient: choline bitartrate, a form of choline — a nutrient your body uses to make acetylcholine, a neurotransmitter involved in memory, muscle control, and other brain functions. Each capsule also contains inactive ingredients (hypromellose, maltodextrin, and stearate) that serve as the capsule material and binders.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports cognition concentration and memory.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Dementia, Infant development, brain health — and 2 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cognitive function, Dementia, Infant development.

The evidence on what choline bitartrate actually does is pretty sparse. For athletic performance, the data suggests it's likely ineffective.

For several other uses — including age-related cognitive decline, Alzheimer's disease, allergic rhinitis, and a liver condition called TPN-associated hepatic steatosis — we simply don't have enough reliable evidence to say either way. Bronchitis likewise lacks sufficient data.

If you're considering this for a specific reason, it's worth talking through with us.

The evidence, ingredient by ingredient Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Choline is generally well tolerated when you stick to normal doses, but high-dose supplements do have a limit: the safe upper intake level is 3.5 grams daily. Above that threshold — especially at 9 grams daily or higher — you may notice a fishy body odor (from how your gut breaks down choline), along with diarrhea, nausea, sweating, and vomiting.

Very high doses like 32 grams have caused more serious gastric upset. Choline is important during pregnancy and breastfeeding, but the safety data advises using only prenatal doses or supplements under your doctor's guidance — not to decide on your own.

Side effects, ingredient by ingredient Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check whether you use atropine or any anticholinergic medication. Minor interaction data exists for atropine; choline may theoretically reduce its effect.

Run your exact medications through the tool below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Choline bitartrate is straightforward: one ingredient, one minor interaction to watch for (atropine), and solid safety data as long as you respect the 3.5-gram daily ceiling. If you don't take anticholinergic drugs, it's a low-interaction choice.

Talk with us before starting if you're pregnant, breastfeeding, or taking any regular medications — we'll make sure there's nothing to worry about.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Choline Bitartrate, straight from the product label.

Brand Pure Nootropics
Barcode (UPC) 854051008047
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316489
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Choline Bitartrate by Pure Nootropics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
854051008047
IngredientAmount% DV
Choline Bitartrate750 mg--
Choline300 mg54%

Other ingredients: Hypromellose, Maltodextrin, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Consult with a healthcare practitioner before taking this.

Do not take this if you are pregnant, nursing or under the age of 18.

Do not take this if you are pregnant, nursing or under the age of 18.

If you experience adverse reactions from taking this product, discontinue immediately and contact a healthcare practitioner.

Keep out of reach of children.

Formulation

Cognition Concentration Memory

Supports Overall Brain function

Always Preservative Free Gluten Free

Lab tested

General Statements

Unlock Your Potential

FDA Statement of Identity

Dietary Supplement

Formula

Formulated with VitaCholine

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

VitaCholine is a registered trademark of Balchem Corporation.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule daily or as recommended by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Choline Bitartrate by Pure Nootropics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Choline Bitartrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Choline Bitartrate by Pure Nootropics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Choline

Interacts with
16 drugs
300 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Other (inactive) ingredients: Hypromellose, Maltodextrin, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Choline Bitartrate by Pure Nootropics Drug Interactions

Want to check YOUR meds against Choline Bitartrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline 16

Individual Drug Interactions

The ingredients in Choline Bitartrate interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Choline Bitartrate interact with drugs. Each result below shows which ingredient is responsible. Choline

Each ingredient & the kinds of drugs it affects

For each ingredient in Choline Bitartrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Choline Bitartrate, from the product label.

Pure Nootropics

See all Pure Nootropics products
Name
Pure Nootropics, LLC
Street Address
P.O. Box 6827
City
Albuquerque
State
NM
ZipCode
87197
Web Address
purenootropics.net
Pharmacist Counseling Corner

Choline Bitartrate by Pure Nootropics: Common Questions

Does Choline Bitartrate by Pure Nootropics interact with any medications?
Yes. Based on its ingredients, Choline Bitartrate has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Choline Bitartrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is choline bitartrate safe during pregnancy or while breastfeeding?
Choline is important during both pregnancy and breastfeeding — your needs actually go up when you're nursing. But the safety data advises using only prenatal or supplement doses under your doctor's guidance, not deciding on your own. Talk with your doctor or pharmacist before you start.
Will this help my memory or brain health?
We don't have enough reliable evidence to say whether choline bitartrate helps with age-related cognitive decline or Alzheimer's disease. Your individual situation might be different, so it's worth discussing with your pharmacist or doctor.
What side effects might I get from choline?
At normal doses, choline is well tolerated. But if you go above 3.5 grams a day, you might notice a fishy body odor. At high doses of 9 grams or more, nausea, vomiting, diarrhea, and sweating are possible. Very high doses can cause serious stomach upset.
Can I use this for athletic performance?
The evidence suggests choline bitartrate is likely ineffective for athletic performance, so it's probably not the right choice if that's your goal.
Does this product have any fillers?
Yes — it contains inactive ingredients like hypromellose, maltodextrin, and stearate, which are used as the capsule material and binders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Choline Bitartrate is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Choline Bitartrate label
Go deeper

The Full Monographs Behind Choline Bitartrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Choline Bitartrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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