Co Q-10 100 mg Ingredients & Drug Interactions
by Member's Mark
What is this page for?
First and foremost: checking Co Q-10 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Co Q-10 100 mg is a dietary supplement by Member's Mark with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Co Q-10 100 mg by Member's Mark
Ask about any prescription or over-the-counter medication and we check it for interactions with Co Q-10 100 mg by Member's Mark — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Co Q-10 100 mg by Member's Mark
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: coenzyme Q-10 at 100 mg per softgel. Coenzyme Q-10 is a compound your body uses to produce energy in your cells and to protect them from damage.
It's also found naturally in foods like fish and meat. The softgel is made up of inactive ingredients—soybean oil, gelatin, glycerin, and a few others—that help deliver the active ingredient.
Does it work?
Moderate evidence
The evidence for coenzyme Q-10 varies by use. It's likely effective for replacing coenzyme Q-10 when your body is deficient in it.
For fibromyalgia, migraine headaches, congestive heart failure, and diabetic nerve pain (neuropathy), the evidence suggests it's possibly effective, but the data aren't as strong. Talk with your pharmacist about whether this dose and form are right for what you're hoping to address.
How safe is it?
Well-documented data
Coenzyme Q-10 is generally well tolerated by most adults when used as directed. In clinical studies, no serious side effects have been reported.
The most common issues are mild gastrointestinal symptoms—appetite suppression, diarrhea, heartburn, nausea, and vomiting—but these happen in less than 1% of people. Headache, dizziness, and insomnia have also been reported rarely.
Skin itching and rash are uncommon. There isn't enough reliable safety data on coenzyme Q-10 during pregnancy, so the best advice is to avoid it unless your doctor specifically recommends it.
Safety data while breastfeeding hasn't been well studied either—check with your doctor before use.
Meds to double-check
Moderate interaction found
Before you take this product, check with your pharmacist if you use warfarin or another blood thinner—coenzyme Q-10 may reduce its effectiveness. Also flag it if you're on chemotherapy, especially alkylating agents, or if you take blood pressure medications.
These are the main medication types that interact with this ingredient.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Coenzyme Q-10 is a decent choice if you're looking to replace a deficiency or explore it for migraine, heart failure, or nerve pain, and you don't take warfarin or chemotherapy. If you're on a blood thinner, blood pressure medication, or cancer drug, talk to your pharmacist first.
Same goes if you're pregnant or breastfeeding—get personalized advice before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Co Q-10 100 mg, straight from the product label.
| Brand | Member's Mark |
|---|---|
| Net contents | 180 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Aug 25, 2015 |
| DSLD ID | 47219 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Co Q-10 100 mg by Member's Mark, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q-10 | 100 mg | -- |
Other ingredients: Soybean Oil, Coenzyme Q-10, Gelatin, Glycerin, purified Water, Titanium Dioxide, Lecithin, Annatto
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
100% MONEY BACK GUARANTEE SUPERIOR QUALITY AND PERFORMANCE
We would like to hear from you with any comments or suggestions. In the continental U.S. or Canada, you can call us at 1-888-698-5034 from 8:30 a.m. to 5:00 p.m. EST Monday - Friday.
Supports Heart Health*
{Softgel} actual size
Health Benefits Heart* Wellness*
Nutrition Information: Coenzyme Q-10 is a powerful antioxidant that is a necessary nutrient for cell function in the body and has been shown in clinical research to have heart health benefits.*
136334 518306 SAM646425
Seals/Symbols
M Member's Mark(R) QUALITY GUARANTEED
Statins (cholesterol-lowering drugs) reduce the natural production of Co Q-10. Statin-induced Co Q-10 deficiency can be prevented with supplemental Co Q-10.
GLUTEN FREE
LABORATORY TESTED QUALITY ASSURED
FDA Statement of Identity
dietary supplement
Suggested/Recommended/Usage/Directions
- One softgel daily
Suggested use: Adults - One softgel daily with food as a dietary supplement.
Formula
- Beneficial for those taking statin drugs*
Contains: Soy.
Precautions
Contains: Soy.
Keep out of the reach of children.
Warning: Pregnant or nursing women, individuals taking medication(s) or persons who have a health condition should consult their physician before using this product.
Safety-sealed. Do not use if printed seal under cap is cut, torn, or missing.
Coenzyme Q-10 is not intended to serve as a replacement for statin therapy, nor should you discontinue taking any prescribed medications while supplementing with Coenzyme Q-10.* Consult your healthcare practitioner.
Storage
Store at 15(0)-30(0)C (59(0)-86(0)F).
Formulation
NO ARTIFICIAL DYES OR FLAVORS - NO SUGAR NO GLUTEN - NO LACTOSE
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Co Q-10 100 mg by Member's Mark label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Co Q-10 100 mg by Member's Mark
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q-10 monograph & interactionsOther (inactive) ingredients: Soybean Oil, Coenzyme Q-10, Gelatin, Glycerin, Purified Water, Titanium Dioxide, Lecithin, Annatto. These complete the product’s ingredient list but are not active constituents.
Co Q-10 100 mg by Member's Mark Drug Interactions
HelloPharmacist Interaction Report
Member's Mark Co Q-10 100 mg contains one active ingredient, coenzyme Q-10, which does interact with certain medications.
The most serious concern is with warfarin (Coumadin), a blood thinner. Coenzyme Q-10 has a vitamin K-like effect that may reduce how well warfarin prevents blood clots; four cases of decreased warfarin effectiveness have been reported.
If you take warfarin, you'll need to check with your pharmacist before starting this product.
Read the full breakdown — every affected drug type, severity by severity
Coenzyme Q-10 may also interfere with chemotherapy drugs, particularly alkylating agents (such as cyclophosphamide). Its antioxidant effect could theoretically reduce the activity of cancer medications that work by creating cellular damage.
Additionally, coenzyme Q-10 might add to the effects of blood pressure medications and lower your blood pressure further. This is a minor interaction, but worth watching for if you're on an antihypertensive drug.
Always run your exact medications through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Co Q-10 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Co Q-10 100 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Co Q-10 100 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10
AltretamineHexalen
How Altretamine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q-10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q-10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q-10 + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Co Q-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Co Q-10 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Co Q-10 100 mg, from the product label.
Member's Mark
- Name
- Sam's West, Inc.
- City
- Bentonville
- State
- AR
- ZipCode
- 72716
Co Q-10 100 mg by Member's Mark: Common Questions
Does Co Q-10 100 mg by Member's Mark interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this lower my blood pressure?
What are the most common side effects?
Can I take this while pregnant?
Is it safe to breastfeed while taking this?
Why is coenzyme Q-10 in the inactive ingredients list too?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Co Q-10 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Co Q-10 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Co Q-10 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC