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Dietary supplement

Copper Gluconate Anyhdrous 1% Ingredients & Drug Interactions

by PureBulk.com

Copper Gluconate Anyhdrous 1% label
See full label image
Powder Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Copper Gluconate Anyhdrous 1% against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Copper Gluconate Anyhdrous 1% is a dietary supplement by PureBulk.com with 1 active ingredient. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 31 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Copper Gluconate Anyhdrous 1% by PureBulk.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Copper Gluconate Anyhdrous 1% by PureBulk.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Copper Gluconate Anyhdrous 1% by PureBulk.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: copper, supplied as copper gluconate anhydrous in a 1% powder form. Copper is an essential mineral your body needs for nerve function, immune support, and collagen formation.

The powder also contains mannitol as an inactive ingredient (filler).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: copper deficiency prevention and treatment.
  • We looked for evidence on: Copper deficiency, Copper supplementation, Mineral repletion, Nutritional deficiency.
  • The strongest evidence on file: Copper is rated "Likely Effective" for Copper deficiency (Natural Medicines).

The evidence supports copper for treating copper deficiency — that's where it's most useful. For Alzheimer's disease, the data suggests it's possibly ineffective.

For acne, chemotherapy-induced anemia, and brain tumors, we don't have enough reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is safe in the amounts found in food and standard supplements, but excess copper can be toxic, so stick to recommended doses. Copper is needed during pregnancy, but stay within recommended amounts and avoid high-dose supplements unless your doctor advises it.

In rare cases, topical copper has caused contact dermatitis (skin irritation). People with diabetes tend to have higher copper levels in their blood than others, though we don't yet know if extra copper worsens diabetes.

Side effects, ingredient by ingredient Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 31 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check if you're taking penicillamine (a Moderate interaction — it reduces penicillamine's absorption, so space them 2 hours apart) or oral contraceptive drugs (a Minor interaction — they can raise your copper levels). Use the medication search tool below to look up your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Copper Gluconate is straightforward if you have a documented copper deficiency and aren't taking penicillamine or long-term birth control. If you're on either of those, check with your pharmacist first.

Stick to recommended doses and don't take high-dose supplements on your own.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Copper Gluconate Anyhdrous 1%, straight from the product label.

Brand PureBulk.com
Net contents 250 g; 8.82 oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 23062
Product type Mineral
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Copper Gluconate Anyhdrous 1% by PureBulk.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
160 mg
Maximum serving Sizes:
160 mg
Servings per container
1562
IngredientAmount% DV
Copper1.6 mg80%

Other ingredients: Mannitol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

WARNING: Potentially TOXIC. Do not take more than 400 milligrams of this product per day (or 4 milligrams per day of elemental copper).

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult with your physician before use.

Keep out of reach of children.

Storage

Storage: Keep dry, cool & dark

Formulation

Free of: Soy, dairy, yeast, gluten and additives.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 160 mg (1/16 tsp) daily, or as directed by a physician. For accurate measurement use an analytical milligram scale.

General Statements

US Standard Measuring Spoons Spoon Size (level) milligrams 1/64 teaspoon 40 1/32 teaspoon 80 1/16 teaspoon 160

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Copper Gluconate Anyhdrous 1% by PureBulk.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Copper Gluconate Anyhdrous 1% label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Copper Gluconate Anyhdrous 1% by PureBulk.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size160 mg Dosage formPowder Servings per container1562 Amounts shown are per serving.

Copper

Interacts with
31 drugs
1.6 mg per serving Form: Copper Gluconate

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Other (inactive) ingredients: Mannitol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Copper Gluconate Anyhdrous 1% by PureBulk.com Drug Interactions

Want to check YOUR meds against Copper Gluconate Anyhdrous 1%?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
31Drugs
1 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Individual Drug Interactions

The ingredients in Copper Gluconate Anyhdrous 1% interact with 31 drugs. Click any drug to see the details.

1 of the 1 ingredient in Copper Gluconate Anyhdrous 1% interact with drugs. Each result below shows which ingredient is responsible. Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Copper Gluconate Anyhdrous 1% with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Copper Gluconate Anyhdrous 1%, from the product label.

PureBulk.com

See all PureBulk.com products
Name
PureBulk.com
City
Roseburg
State
OR
ZipCode
97471
Phone Number
(541) 679-1500
Web Address
PureBulk.com
Pharmacist Counseling Corner

Copper Gluconate Anyhdrous 1% by PureBulk.com: Common Questions

Does Copper Gluconate Anyhdrous 1% by PureBulk.com interact with any medications?
Yes. Based on its ingredients, Copper Gluconate Anyhdrous 1% has a known interaction with 31 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Copper Gluconate Anyhdrous 1% contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control?
Yes, but it's a consideration. Oral contraceptives can increase copper levels in your blood. It's mild, but mention it to your pharmacist so they can monitor you or adjust your dose if needed.
What's copper actually for?
Your body uses copper for nerve function, immune support, and building collagen (the protein that keeps skin and connective tissue strong). This supplement is most useful if you have a documented copper deficiency.
Is this safe to take every day?
Yes, as long as you stay within recommended amounts. Excess copper can be toxic, so don't exceed the dose on the label without talking to your doctor.
Will this help with Alzheimer's disease?
The evidence suggests it's not effective for Alzheimer's, so this wouldn't be the right reason to take it.
Is it safe in pregnancy?
Copper is actually needed during pregnancy, and the recommended amounts are considered safe. Just avoid high-dose supplements unless your doctor tells you to take them.
What's mannitol doing in here?
Mannitol is an inactive ingredient — a filler that helps make the powder easier to handle and measure. It's not the active part; copper is what does the work.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Copper Gluconate Anyhdrous 1% is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Copper Gluconate Anyhdrous 1% label
Go deeper

The Full Monographs Behind Copper Gluconate Anyhdrous 1%’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

Copper Gluconate Anyhdrous 1%'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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