CoQ10 250 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CoQ10 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ10 250 mg is a dietary supplement by Fresh Nutrition with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ10 250 mg by Fresh Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 250 mg by Fresh Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ10 250 mg by Fresh Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: coenzyme Q10 at 250 mg per capsule. CoQ10 is a natural compound your cells use to produce energy and protect themselves from oxidative stress.
The capsule also contains rice bran oil, gelatin, vegetable glycerin, and less than 2% of other inactive ingredients.
Does it work?
Strong evidence
Coenzyme Q10 is likely effective for treating coenzyme Q10 deficiency itself. It's rated possibly effective for fibromyalgia, migraine headache, congestive heart failure (CHF), and diabetic neuropathy — meaning some clinical research supports benefit, but the evidence isn't yet conclusive.
The facts we hold don't establish effectiveness for other uses.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when taken as directed. Gastrointestinal side effects like appetite suppression, diarrhea, heartburn, nausea, and vomiting can occur, but these happen in less than 1% of users and are often reduced when daily doses above 100 mg are split throughout the day.
Headache, dizziness, insomnia, and skin itching have also been reported rarely. Safety during pregnancy has not been well studied, so the data advises against it unless your doctor advises otherwise.
For breastfeeding, safety data is limited — talk with your doctor or pharmacist about whether it's right for you.
Meds to double-check
Moderate interaction found
Before you start, check with your doctor or pharmacist if you take chemotherapy (especially alkylating agents like cyclophosphamide), warfarin or other blood thinners, or blood pressure medications. No interactions are documented in our data for other medication types.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 may help if you have a documented deficiency or are interested in its possible benefits for migraines, heart failure, fibromyalgia, or nerve pain. If you take blood thinners, blood pressure medications, or chemotherapy drugs, you'll need to check with your doctor or pharmacist first — interactions are documented.
A small number of people experience mild stomach upset; taking larger daily doses in split doses may help.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ10 250 mg, straight from the product label.
| Brand | Fresh Nutrition |
|---|---|
| Barcode (UPC) | 850008467271 |
| Net contents | 60 Softgel Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 241918 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ10 250 mg by Fresh Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q10 | 250 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Contains <2% of
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Vegan
Non GMO Gluten free Soy free
No artificial colors. No artificial flavors. No preservatives. Made with Non-GMO, all natural ingredients!
All natural
Free radical scavenger May promote a healthy heart May help lower blood pressure May promote healthy gums May boost immune health
Fresh Nutrition produces the most potent and highest quality CoQ10. Our raw materials are carefully sourced and cultivated; contain no fillers, additives, and are manufactured domestically in a cGMP facility. Thank you for choosing Fresh!
Formula
CoQ10 The human body naturally produces the antioxidant Coenzyme Q10 (CoQ10). Some studies have shown that CoQ10 may be beneficial for general health and well being. CoQ10 levels decrease in your body as you age, maintain your health with our CoQ10 supplement.
Made with Non-GMO, all natural ingredients!
General Statements
Fresh Nutrition Our goal is to create high-quality natural products using both organic and responsibly sourced ingredients to optimize health and well-being.
Suggested/Recommended/Usage/Directions
Recommended Dosage Take two (2) softgel capsules daily with sufficient water before a meal.
Seals/Symbols
Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.
Made in USA
FDA Statement of Identity
Dietary Supplement
Precautions
Contains soy ingredients.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ10 250 mg by Fresh Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ10 250 mg by Fresh Nutrition
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Softgel Capsule(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Coenzyme Q10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.
CoQ10 250 mg by Fresh Nutrition Drug Interactions
HelloPharmacist Interaction Report
Fresh Nutrition's CoQ10 250 mg can interact with several medication types through its coenzyme Q10 content.
The most serious concern is with chemotherapy drugs called alkylating agents (such as cyclophosphamide) — coenzyme Q10's antioxidant activity may theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative stress these drugs rely on to be effective.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take warfarin (Coumadin), a blood thinner. Coenzyme Q10 has chemical similarities to vitamin K, which promotes clotting, and may reduce warfarin's effectiveness.
A small number of cases of decreased warfarin effect have been reported with coenzyme Q10 use. Additionally, if you take blood pressure medications, coenzyme Q10 might add to their effect — this is listed as a minor concern, though some studies show it can lower blood pressure while others conflict.
Altogether, these interactions span 198 individual medications. Before you start this supplement, run your exact medications through the checker on this page, and talk it over with your doctor or pharmacist if you take chemotherapy, warfarin, or blood pressure drugs.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ10 250 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ10 250 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in CoQ10 250 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q10
AltretamineHexalen
How Altretamine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Coenzyme Q10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Coenzyme Q10 + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with CoQ10 250 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ10 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ10 250 mg, from the product label.
Fresh Nutrition
See all Fresh Nutrition products- Name
- Fresh Nutrition
- Street Address
- 1601 Dove St
- City
- Newport Beach
- State
- California
- ZipCode
- 92660
- Web Address
- www.fresh-nutrition.com
CoQ10 250 mg by Fresh Nutrition: Common Questions
Does CoQ10 250 mg by Fresh Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly is coenzyme Q10, and why would I take it?
Will CoQ10 interact with my blood thinner?
What side effects might I experience?
Is CoQ10 safe to take while pregnant?
Can I take this if I'm taking cancer treatment?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ10 250 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ10 250 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ10 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
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