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Dietary supplement

Cornsilk Ingredients & Drug Interactions

by Pure Herbs

Cornsilk label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cornsilk against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cornsilk is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 290 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Corn Silk Stamen, Stigma and Style Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cornsilk by Pure Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Cornsilk by Pure Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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Computed from our clinical databases

HelloPharmacist Scorecard of Cornsilk by Pure Herbs

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Corn Silk.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 290 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cornsilk, straight from the product label.

Brand Pure Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278767
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cornsilk by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
IngredientAmount% DV
Corn Silk Stamen, Stigma and Style Extract1986 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Helps to maintain a healthy urinary tract and relieve occasional urinary discomfort.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cornsilk by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cornsilk label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cornsilk by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Corn Silk Stamen, Stigma and Style Extract

Interacts with
290 drugs
1986 mg per serving Form: Zea sp. Stamen Extract, Zea sp. Stigma Extract, Zea sp. Style Extract

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence...

Corn Silk Stamen, Stigma and Style Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cornsilk by Pure Herbs Drug Interactions

Cornsilk contains a single active ingredient, and it has known interactions with 290 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Cornsilk?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
290Drugs
290 Moderate

Ingredients driving the most interactions

Corn Silk Stamen, Stigma and Style Extract 290

Individual Drug Interactions

The ingredients in Cornsilk interact with 290 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cornsilk interact with drugs. Each result below shows which ingredient is responsible. Corn Silk Stamen, Stigma and Style Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cornsilk with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Corn Silk Stamen, Stigma and Style Extract5 drug types · 290 drugs

Antidiabetes Drugs

Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.

Likelihood Possible Evidence D
Corticosteroids

Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.

Likelihood Possible Evidence D
Diuretic Drugs

Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.

Likelihood Likely Evidence D
Corn Silk Stamen, Stigma and Style Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cornsilk, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Cornsilk by Pure Herbs: Common Questions

Does Cornsilk by Pure Herbs interact with any medications?
Yes. Based on its ingredients, Cornsilk has a known interaction with 290 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cornsilk contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cornsilk is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cornsilk label
Go deeper

The Full Monographs Behind Cornsilk’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Corn Silk

Interacts with 290 drugs

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...

Read the full Corn Silk monograph →
Sources

Sources & How We Checked

Cornsilk's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Corn Silk 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

See these in context on the Corn Silk monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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