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Dietary supplement

Cucumber Extract Ingredients & Drug Interactions

by BulkSupplements.com

Cucumber Extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cucumber Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cucumber Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for hydration and skin care, cooling and soothing puffy eyes, mild diuretic effect.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cucumber Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cucumber Extract by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Cucumber Extract by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cucumber Extract by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: cucumber fruit extract. That's it — no fillers, binders, or other ingredients listed.

Cucumber extract comes from the fruit of the cucumber plant and is concentrated in powder form. The active compounds in that extract, particularly from cucumber seeds, are what may affect blood sugar levels.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cucumber product and its label doesn't state a use — see Cucumber's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cucumber extract isn't well established in our data. For burns, diabetes, high cholesterol (hyperlipidemia), high blood pressure (hypertension), and osteoarthritis, the scientific evidence is either missing or too limited to rate how well it works.

If you're considering it for one of those conditions, the facts we hold don't support a clear claim either way.

The evidence, ingredient by ingredient Cucumber

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cucumber as a food is widely eaten and generally well tolerated. Cucumber extract and seed extract also appear to be well tolerated when taken by mouth, with no common side effects reported.

Topically (on skin), the extract may occasionally cause allergic eczema, redness, or irritation in sensitive people. Anaphylaxis (a severe whole-body allergic reaction) is rare but has been reported after eating cucumber.

Cucumber as food is considered safe during pregnancy and while breastfeeding, but concentrated supplements or extracts haven't been studied in those situations. There isn't enough data to know whether the concentrated extract is safe if you're pregnant or nursing — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Cucumber

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cucumber.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on any antidiabetes drugs (blood sugar–lowering medications). Cucumber extract may add to their effect and increase your risk of low blood sugar.

Talk with your doctor or pharmacist about whether it's safe to combine them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cucumber Extract is a simple, single-ingredient product that's well tolerated by most people. The main caution is for anyone taking blood sugar–lowering medications — this product may increase the risk of low blood sugar.

If that applies to you, check with your doctor or pharmacist before starting it and be prepared to monitor your blood glucose more often. For other uses, the evidence we hold doesn't establish how well it works.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cucumber Extract, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X002KUJANH
Net contents 1 Kilogram(s); 35.3 Ounce(s); 2.2 Pound(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 294455
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cucumber Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
2000
UPC/BARCODE
X002KUJANH
IngredientAmount% DV
Cucumber Fruit Extract500 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BulkSupplements.com Clean & Pure Bulk Supplements

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Color may vary

Storage

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

Store in a dry, cool place

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

General Statements

New

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cucumber Extract by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cucumber Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cucumber Extract by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container2000 Amounts shown are per serving.

Cucumber Fruit Extract

Interacts with
86 drugs
500 mg per serving

Cucumber is a common food vegetable that is mostly water and is generally safe to eat. As a supplement or skincare ingredient it is popular for hydrat...

Cucumber Fruit Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cucumber Extract by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Cucumber Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Cucumber Fruit Extract 86

Individual Drug Interactions

The ingredients in Cucumber Extract interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cucumber Extract interact with drugs. Each result below shows which ingredient is responsible. Cucumber Fruit Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cucumber Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cucumber Fruit Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, cucumber seed might have additive effects with antidiabetes drugs and may increase the risk of hypoglycemia.
Animal research shows that cucumber seed extract can decrease blood glucose levels. Monitor blood glucose levels closely.

Likelihood Possible Evidence D
Cucumber Fruit Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cucumber Extract, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Cucumber Extract by BulkSupplements.com: Common Questions

Does Cucumber Extract by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Cucumber Extract has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cucumber Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Eating cucumber as a food is fine during pregnancy and breastfeeding, but we don't have safety data for concentrated extracts like this one in those situations. There isn't enough information to know either way. Talk with your doctor or pharmacist about whether this supplement is right for you.
Does cucumber extract actually work for diabetes?
The scientific evidence isn't strong enough to rate how well it works for diabetes. Animal studies suggest cucumber seed may lower blood sugar, but we don't have reliable human evidence yet. And remember — if you already take a diabetes medication, you'd need to monitor your blood sugar carefully because this product might lower it further.
Are there any side effects I should know about?
Cucumber extract is generally well tolerated when taken by mouth, with no common side effects reported. On skin, it may occasionally cause redness, eczema, or irritation. Severe allergic reaction (anaphylaxis) is very rare but has been reported after eating cucumber.
What exactly is in this product?
Just one active ingredient: cucumber fruit extract in powder form. There are no other fillers or binders listed.
Should I be concerned about an allergic reaction?
Serious allergic reactions to cucumber are rare. Most people tolerate the extract well. If you've had an allergy to cucumber or other plants in the same family before, or if you have a known food allergy history, mention that to your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cucumber Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cucumber Extract label
Go deeper

The Full Monographs Behind Cucumber Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cucumber

Interacts with 86 drugs

Cucumber is a common food vegetable that is mostly water and is generally safe to eat. As a supplement or skincare ingredient it is popular for hydration and soothing the skin, but solid hum...

Read the full Cucumber monograph →
Sources

Sources & How We Checked

Cucumber Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cucumber 4 references
  1. Fiume MM, Bergfeld WF, Belsito DV, et al. Safety assessment of Cucumis sativus (cucumber)-derived ingredients as used in cosmetics. Int J Toxicol. 2014;33(2 suppl):47S-64S.
  2. Vlaicu PC, Rusu LC, Ledesma A, et al. Cucumber anaphylaxis in a latex-sensitized patient. J Investig Allergol Clin Immunol. 2011;21(3):236-9.
  3. Minaiyan M, Zolfaghari B, Kamal A. Effect of hydroalcoholic and buthanolic extract of Cucumis sativus seeds on blood glucose level of normal and streptozotocin-induced diabetic rats. Iran J Basic Med Sci. 2011;14(5):436-42.
  4. Zachariae CO. Cucumber contact dermatitis. Contact Dermatitis. 2000;43(4):240-1. DOI

See these in context on the Cucumber monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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