Emulsified CoQ10 30 mg Softgel Ingredients & Drug Interactions
by VitalBulk
What is this page for?
First and foremost: checking Emulsified CoQ10 30 mg Softgel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Emulsified CoQ10 30 mg Softgel is a dietary supplement by VitalBulk with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are SEDDS CoQPure Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Emulsified CoQ10 30 mg Softgel by VitalBulk
Ask about any prescription or over-the-counter medication and we check it for interactions with Emulsified CoQ10 30 mg Softgel by VitalBulk — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Emulsified CoQ10 30 mg Softgel by VitalBulk
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: coenzyme Q10 (also called CoQ10), a compound your body makes naturally and that plays a role in energy production in your cells. The formulation uses an emulsified delivery system — SEDDS CoQPure Complex — designed to improve how your body absorbs it.
The softgel capsule itself is made from gelatin and glycerin.
Does it work?
Strong evidence
Coenzyme Q10 is rated Likely Effective for treating coenzyme Q10 deficiency. It's rated Possibly Effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy — meaning there's some research support but evidence isn't yet conclusive.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when taken as directed. The most common side effects are gastrointestinal — appetite suppression, diarrhea, epigastric discomfort (stomach pain), heartburn, nausea, and vomiting — and these occur in less than 1% of people; dividing doses above 100 mg daily may help.
Headache, dizziness, insomnia, and skin itching or rash have been reported rarely. Safety during pregnancy has not been well studied; there isn't enough reliable data to know either way, so talk with your doctor or pharmacist for personalized advice.
Safety while breastfeeding has also not been well studied — discuss this with your doctor or pharmacist before use.
Meds to double-check
Moderate interaction found
Before you start, double-check these medication types: warfarin or other blood thinners (Moderate-severity risk that CoQ10 may weaken the drug's effect); chemotherapy drugs, especially alkylating agents like cyclophosphamide (Moderate-severity concern that CoQ10's antioxidant activity could shield cancer cells); and blood pressure medications (Minor-severity risk of added blood pressure lowering). Ask your doctor or pharmacist to review your list.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 makes sense if you're deficient in it or exploring it for migraine, heart health, or nerve pain — talk with your doctor about whether it fits your situation. If you take a blood thinner like warfarin or a chemotherapy drug, you'll need to check with your doctor or pharmacist first, since this supplement may interfere with how they work.
Similarly, if you're on blood pressure medication, clear it before starting. Go through your exact medications with the checker on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Emulsified CoQ10 30 mg Softgel, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Emulsified CoQ10 30 mg Softgel by VitalBulk, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q10 | 30 mg | -- |
| SEDDS CoQPure Complex | 500 mg | -- |
Other ingredients: Gelatin, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Actual color and size
In case of adverse event call 855-885-2855
General
CoQ
FDA Statement of Identity
Food/Dietary Supplement
Seals/Symbols
Certified NonGE Tested
Suggested/Recommended/Usage/Directions
Suggested Use: Take one (1) softgel daily with food. Do not exceed recommended daily dose unless directed by your health care practitioner.
Precautions
Do not exceed recommended daily dose unless directed by your health care practitioner.
Keep out of reach of children in a cool, dry place.
This product may be produced in a facility that also makes products containing milk, eggs, fish, crustacean shellfish, tree nuts, wheat, peanuts, and soy.
Food supplements should not be used as a substitute for a varied diet.
Caution: Not recommended for children.
Consult a healthcare practitioner if pregnant or nursing, taking medication, or have a medical condition.
Storage
Keep out of reach of children in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Emulsified CoQ10 30 mg Softgel by VitalBulk label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Emulsified CoQ10 30 mg Softgel by VitalBulk
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
SEDDS CoQPure Complex
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
SEDDS CoQPure Complex monograph & interactionsOther (inactive) ingredients: Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.
Emulsified CoQ10 30 mg Softgel by VitalBulk Drug Interactions
HelloPharmacist Interaction Report
VitalBulk's Emulsified CoQ10 contains one active ingredient — coenzyme Q10 — which interacts with blood thinners, chemotherapy drugs, and blood pressure medications.
The most serious concern is with warfarin (a blood thinner), where coenzyme Q10 may reduce how well the drug works; four cases of decreased warfarin effectiveness have been reported, and this is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Coenzyme Q10 may also interfere with chemotherapy drugs that rely on free radicals to kill cancer cells — alkylating agents like cyclophosphamide are a Moderate-severity concern because the supplement's antioxidant effect could theoretically shield tumor cells from the drug's activity.
Blood pressure medications (antihypertensives) warrant a Minor-severity watch, since some studies suggest coenzyme Q10 can lower blood pressure on its own; combined with a blood pressure drug, this could add up to a stronger drop than intended.
Altogether, these interactions span 198 individual medications. Before you start, use the medication checker on this page to verify your exact prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Emulsified CoQ10 30 mg Softgel?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Emulsified CoQ10 30 mg Softgel interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Emulsified CoQ10 30 mg Softgel interact with drugs. Each result below shows which ingredient is responsible. SEDDS CoQPure Complex
AltretamineHexalen
How Altretamine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Sedds Coqpure Complex + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Sedds Coqpure Complex + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Sedds Coqpure Complex + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Sedds Coqpure Complex + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Sedds Coqpure Complex + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Sedds Coqpure Complex + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Emulsified CoQ10 30 mg Softgel — through 1 ingredient. Tap an ingredient for the detail:
Sedds Coqpure ComplexAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Sedds Coqpure Complex + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Emulsified CoQ10 30 mg Softgel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
SEDDS CoQPure Complex
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Emulsified CoQ10 30 mg Softgel, from the product label.
VitalBulk
See all VitalBulk products- Street Address
- 440 Kings Village Rd
- City
- Scotts Valley
- State
- CA
- ZipCode
- 95066
- Phone Number
- 855-885-2855
Emulsified CoQ10 30 mg Softgel by VitalBulk: Common Questions
Does Emulsified CoQ10 30 mg Softgel by VitalBulk interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does CoQ10 actually work?
What's the SEDDS CoQPure Complex in this softgel?
What side effects should I watch for?
Is it safe to take while breastfeeding?
Is it safe in pregnancy?
Does this have fillers or anything else in it?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Emulsified CoQ10 30 mg Softgel is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Emulsified CoQ10 30 mg Softgel’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Emulsified CoQ10 30 mg Softgel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC