Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Energize Ingredients & Drug Interactions

by New Earth

Energize label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Energize against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Energize is a dietary supplement by New Earth with 6 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 516 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Reishi Mushroom, organic Microalgae, Ubiquinol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Energize by New Earth

Ask about any prescription or over-the-counter medication and we check it for interactions with Energize by New Earth — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Energize by New Earth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.75 Gram(s)) without saying how much of each component you get.

Energize contains 6 active ingredients. The main one is organic microalgae (blue-green algae), which is a nutrient-dense whole-food source.

You also get ubiquinol, the reduced form of coenzyme Q10, which your cells use to produce energy. Reishi mushroom, olive leaf extract, and organic virgin coconut oil round out the blend.

A proprietary blend combines some of these in a formula the manufacturer doesn't fully disclose on the label. The softgels also contain inactive ingredients — modified food starch, carrageenan, sorbitol, glycerin, water, annatto, organic olive oil, sunflower lecithin, and yellow beeswax — which are fillers, thickeners, and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Natural cellular energy and heart health.
  • We looked for evidence on: Fatigue, Cancer-related fatigue, Chemotherapy-related fatigue, Chronic fatigue syndrome (CFS), Athletic performance, Exercise-induced muscle soreness — and 4 related terms.
  • The strongest evidence on file: Coenzyme Q10 is rated "Possibly Effective" for Congestive heart failure (CHF) (Natural Medicines).
  • Also on file: Coenzyme Q10 is rated "Possibly Ineffective" for Chemotherapy-related fatigue.
  • Also on file: Coenzyme Q10 is rated "Likely Ineffective" for Athletic performance.

The evidence is mixed and often limited. Blue-green algae is possibly effective for high blood pressure, but the data for acne, hay fever, iron deficiency anemia, and arsenic poisoning is insufficient to rate.

Coenzyme Q10 (ubiquinol) is likely effective for coenzyme Q10 deficiency itself, and possibly effective for fibromyalgia, migraines, heart failure, and diabetic nerve pain. Reishi mushroom has been rated possibly ineffective for high cholesterol, though there isn't enough data for altitude sickness, Alzheimer's, or athletic performance.

Olive leaf extract has insufficient evidence for all the conditions listed — osteoporosis, indigestion, respiratory infections, shingles, flu, and arthritis. Coconut oil is also rated insufficient evidence for diabetes, cholesterol, obesity, and lichen planus.

The evidence, ingredient by ingredient Blue-green Algae Coconut Coenzyme Q10 Olive Reishi Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blue-green algae is generally well tolerated, but quality varies widely — some products are contaminated with toxins or heavy metals, so caution is needed. Common side effects include stomach cramps, bloating, diarrhea, dizziness, fatigue, gas, headache, nausea, and vomiting.

Allergic reactions ranging from hives to anaphylaxis have been reported, and a small number of users taking 2.3 grams daily experienced mild gum bleeding or bruising. Coenzyme Q10 is generally well tolerated; serious adverse effects haven't been reported in clinical studies.

Gastrointestinal side effects like appetite loss, diarrhea, heartburn, nausea, and vomiting occur in fewer than 1% of patients, especially when doses above 100 mg are split throughout the day. Headache, dizziness, and insomnia have been reported rarely, as have skin itching and allergic rash.

Coconut oil is safe in food amounts but causes serious allergic reactions in sensitive people — about half result in anaphylaxis. Reishi mushroom is generally well tolerated short-term, but long-term safety is unknown.

Common side effects are dizziness, dry mouth, itching, nausea, rash, and stomach upset. Olive leaf extract is well tolerated; headache and stomach discomfort are most common.

We have no pregnancy or breastfeeding data for blue-green algae, olive leaf, or reishi mushroom on file, so talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Blue-green Algae Coconut Coenzyme Q10 Olive Reishi Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Reishi Mushroom, Blue-green Algae, Coenzyme Q10, Coconut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 516 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Energize, check with your pharmacist if you're on warfarin or any other blood thinner — ubiquinol may reduce its effectiveness (Moderate severity). Also double-check if you take blood pressure medications or diabetes drugs; blue-green algae, reishi mushroom, and coconut oil can affect how they work (Moderate to Minor severity).

And if you're on chemotherapy, particularly alkylating agents, mention ubiquinol to your oncology team (Moderate).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Energize may be worth trying if you're looking for a whole-food energy blend with some evidence behind ingredients like CoQ10 for migraine or muscle energy. But if you take warfarin, blood thinners, blood pressure medication, or diabetes medication, check with your pharmacist first — this product can interfere with all three.

Pregnant or breastfeeding? Talk to your doctor, since safety data is incomplete for some ingredients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Energize, straight from the product label.

Brand New Earth
Net contents 30 Vegetarian Softgel(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 271445
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Energize by New Earth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Total Fat0.5 Gram(s)1%
organic Microalgae0 NP--
Proprietary Blend0.75 Gram(s)--
Calories5 Calorie(s)--
organic virgin Coconut Oil0 NP--
Ubiquinol100 mg--
Olive leaf extract0 NP--
organic Reishi Mushroom0 NP--
Oyster Mushroom Extract0 NP--

Other ingredients: modified Food Starch, Carrageenan, Sorbitol, Glycerin, Water, Annatto, organic Olive Oil, Sunflower Lecithin, yellow Beeswax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Natural Cellular Energy Optimal cellular energy and heart health are key ingredients in a vital, healthy life. Energize is a proprietary blend of pure ubiquinol, reishi and oyster mushroom extracts, polyphenols from olive leaves, and our own organic Wild Microalgae, designed to activate cellular energy to support a healthy heart and strong cardiovascular system. Energize your life today! Promotes heart and cardiovascular health Supports optimal cellular energy

Product of USA

Energize is a proprietary blend of pure ubiquinol, reishi and oyster mushroom extracts, polyphenols from olive leaves, and our own organic Wild Microalgae, designed to activate cellular energy to support a healthy heart and strong cardiovascular system.

Formula

Includes 100 mg bioavailable CoQ10 (Ubiquinol)

Suggested/Recommended/Usage/Directions

Suggested Use: 1 vegetarian softgel once a day. You may wish to adjust this amount based on individual needs.

Storage

Keep in a cool, dry place.

General Statements

Please Recycle

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Contains: tree nuts (coconut)

Brand IP Statement(s)

Q+, Kaneka Ubiquinol and the quality seal are registered or pending trademarks of Kaneka Corp. Copyright 2021 New Earth Life Sciences, Inc.

Seals/Symbols

Made with Quality Q+ Kaneka Ubiquinol

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Energize by New Earth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Energize label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Energize by New Earth

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0.75 Gram(s) per serving

Other (inactive) ingredients: Modified Food Starch, Carrageenan, Sorbitol, Glycerin, Water, Annatto, Organic Olive Oil, Sunflower Lecithin, Yellow Beeswax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Energize by New Earth Drug Interactions

Want to check YOUR meds against Energize?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
516Drugs
516 Moderate

Ingredients driving the most interactions

organic Reishi Mushroom 375
organic Microalgae 327
Ubiquinol 198
organic virgin Coconut Oil 86

Individual Drug Interactions

The ingredients in Energize interact with 516 drugs. Click any drug to see the details.

4 of the 6 ingredients in Energize interact with drugs. Each result below shows which ingredient is responsible. organic Reishi Mushroom organic Microalgae Ubiquinol organic virgin Coconut Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Energize with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Reishi Mushroom3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
organic Reishi Mushroom full monograph & interactions

organic Microalgae3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.

Likelihood Unlikely Evidence D
Antidiabetes Drugs

Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.

Likelihood Possible Evidence D
organic Microalgae full monograph & interactions

Ubiquinol3 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Ubiquinol full monograph & interactions

organic virgin Coconut Oil1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
organic virgin Coconut Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Energize, from the product label.

New Earth

See all New Earth products
Name
New Earth Life Sciences, Inc.
Street Address
565 Century Court
City
Klamath Falls
State
OR
ZipCode
97601
Phone Number
800.800.1300
Web Address
www.NewEarth.com
Pharmacist Counseling Corner

Energize by New Earth: Common Questions

Does Energize by New Earth interact with any medications?
Yes. Based on its ingredients, Energize has a known interaction with 516 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Energize contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help with energy and tiredness?
The product is called Energize and contains CoQ10, which your cells use to make energy, but we don't have effectiveness data on file specifically for fatigue or tiredness in this product's monographs. CoQ10 is possibly effective for fibromyalgia and diabetic nerve pain, and likely effective for CoQ10 deficiency itself. Your mileage may vary.
Can I take this if I'm on blood pressure medication?
You should check with your pharmacist first. Both reishi mushroom and CoQ10 can lower blood pressure, so taking them alongside blood pressure drugs could add up and cause your pressure to drop too low. The same goes for diabetes medication — blue-green algae, reishi, and coconut oil all theoretically lower blood sugar further.
What side effects might I experience?
Blue-green algae commonly causes stomach cramps, bloating, diarrhea, gas, nausea, or dizziness. CoQ10 may cause gastrointestinal discomfort like heartburn or nausea in fewer than 1% of people. Reishi mushroom might cause dizziness, dry mouth, itching, nausea, rash, or stomach upset. Most people tolerate these ingredients, but allergic reactions including hives or anaphylaxis can occur with blue-green algae or coconut oil in sensitive individuals.
Is the blue-green algae safe?
Blue-green algae from quality sources is generally well tolerated. The caution is that quality varies — some products can be contaminated with toxins or heavy metals. Choose a reputable brand and talk to your pharmacist if you have concerns.
Can I take this while pregnant or breastfeeding?
Coconut oil is likely safe during pregnancy and lactation, but we don't have enough safety data on file for blue-green algae, olive leaf extract, or reishi mushroom in pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What's in the proprietary blend, and why isn't it fully listed?
The proprietary blend combines some of the ingredients in this formula, but manufacturers don't always disclose the exact amounts or order to protect their trade secret. The individual ingredient names are listed separately on the label so you can research each one.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Energize label
Go deeper

The Full Monographs Behind Energize’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blue-green Algae

Interacts with 327 drugs

Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...

Read the full Blue-green Algae monograph → Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph →
Sources

Sources & How We Checked

Energize's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 91 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blue-green Algae 22 references
  1. Jensen GS, Ginsberg DJ, Huerta P, et al. Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA 2000;2:50-6.
  2. Iwasa M, Yamamoto M, Tanaka Y, et al. Spirulina-associated hepatotoxicity. Am J Gastroenterol 2002;97:3212-13. PubMed
  3. Hayashi O, Katoh T, Okuwaki Y. Enhancement of antibody production in mice by dietary Spirulina platensis. J Nutr Sci Vitaminol (Tokyo) 1994;40:431-41.. PubMed
  4. Vitale S, Miller NR, Mejico LJ, et al. A randomized, placebo-controlled, crossover clinical trial of super blue-green algae in patients with essential blepharospasm or Meige syndrome. Am J Ophthalmol 2004;138:18-32. PubMed
  5. Mani UV, Desai S, Iyer U. Studies on the long-term effect of spirulina supplementation on serum lipid profile and glycated proteins in NIDDM patients. J Nutraceut 2000;2(3):25-32. DOI
  6. Chiu HF, Yang SP, Kuo YL, et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. Br J Nutr 2006;95:435-40. PubMed
  7. Hsiao G, Chou PH, Shen MY, et al. C-phycocyanin, a very potent and novel platelet aggregation inhibitor from Spirulina platensis. J Agric Food Chem 2005;53:7734-40.
  8. Katz M, Levine AA, Kol-Degani H, Kav-Venaki L. A compound herbal preparation (CHP) in the treatment of children with ADHD: a randomized controlled trial. J Atten Disord 2010;14:281-91. PubMed
  9. Madhyastha, H. K., Radha, K. S., Sugiki, M., Omura, S., and Maruyama, M. Purification of c-phycocyanin from Spirulina fusiformis and its effect on the induction of urokinase-type plasminogen activator from calf pulmonary endothelial cells. Phytomedicine PubMed
  10. Mazokopakis, E. E., Karefilakis, C. M., Tsartsalis, A. N., Milkas, A. N., and Ganotakis, E. S. Acute rhabdomyolysis caused by Spirulina (Arthrospira platensis). Phytomedicine. 2008;15(6-7):525-527. PubMed
  11. Halidou, Doudou M., Degbey, H., Daouda, H., Leveque, A., Donnen, P., Hennart, P., and Dramaix-Wilmet, M. [The effect of spiruline during nutritional rehabilitation: systematic review]. Rev.Epidemiol.Sante Publique 2008;56(6):425-431.
  12. Konno, T., Umeda, Y., Umeda, M., Kawachi, I., Oyake, M., and Fujita, N. [A case of inflammatory myopathy with widely skin rash following use of supplements containing Spirulina]. Rinsho Shinkeigaku 2011;51(5):330-333. PubMed
  13. Le TM, Knulst AC, Röckmann H. Anaphylaxis to Spirulina confirmed by skin prick test with ingredients of Spirulina tablets. Food Chem Toxicol 2014;74:309-10. PubMed
  14. Rzymski P, Niedzielski P, Kaczmarek N, Jurczak T, Klimaszyk P. The multidisciplinary approach to safety and toxicity assessment of microalgae-based food supplements following clinical cases of poisoning. Harmful Algae 2015;46:34-42. DOI
  15. Petrus M, Culerrier R, Campistron M, et al. First case report of anaphylaxis to spirulin: identification of phycocyanin as responsible allergen. Allergy 2010;65(7):924-5. PubMed
  16. Marles RJ, Barrett ML, Barnes J, et al. United States Pharmacopeia safety evaluation of spirulina. Crit Rev Food Sci Nutr 2011;51(7):593-604. PubMed
  17. Majdoub H, Ben Mansour M, Chaubet F, et al. Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis. Biochim Biophys Acta 2009;1790(10):1377-81. PubMed
  18. Cha BG, Kwak HW, Park AR, et al. Structural characteristics and biological performance of silk fibroin nanofiber containing microalgae spirulina extract. Biopolymers 2014;101(4):307-18. PubMed
  19. Jensen GS, Drapeau C, Lenninger M, Benson KF. Clinical safety of a high dose of phycocyanin-enriched aqueous extract from Arthrospira (Spirulina) platensis: results from a randomized, double-Blind, placebo-controlled study with a focus on anticoagulant ac
  20. Hamedifard Z, Milajerdi A, Reiner Z, Taghizadeh M, Kolahdooz F, Asemi Z. The effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized con
  21. Moradi S, Zobeiri M, Feizi A, Clark CCT, Entezari MH. The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative
  22. Ghanbari F, Amerizadeh A, Behshood P, Moradi S, Asgary S. Effect of microalgae arthrospira on biomarkers of glycemic control and glucose metabolism: a systematic Review and meta-analysis. Curr Probl Cardiol 2022;47(10):100942. PubMed

See these in context on the Blue-green Algae monograph →

Coconut 10 references
  1. Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
  2. Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
  3. Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
  4. Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
  5. Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
  6. Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
  7. 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
  8. Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
  9. Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
  10. Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed

See these in context on the Coconut monograph →

Coenzyme Q10 40 references
  1. Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
  2. Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
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See these in context on the Coenzyme Q10 monograph →

Olive 2 references
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See these in context on the Olive monograph →

Reishi Mushroom 17 references
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See these in context on the Reishi Mushroom monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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