Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Essential Immune Ingredients & Drug Interactions

by Organic India

Essential Immune label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Essential Immune against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Essential Immune is a dietary supplement by Organic India with 3 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 331 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Krishna Tulsi, Katuki. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Essential Immune by Organic India

Ask about any prescription or over-the-counter medication and we check it for interactions with Essential Immune by Organic India — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Essential Immune by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Essential Immune contains three active ingredients: organic Krishna Tulsi (also called holy basil), organic Vana Tulsi, and Katuki (picrorhiza). These are combined in a vegetable-based pullulan capsule.

Krishna Tulsi and Katuki are used traditionally to support immune function, though the clinical evidence for their effectiveness remains limited in most areas.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: daily maintenance of healthy immune function.
  • We looked for evidence on: Respiratory tract infections, Immunocompetence, Infection prevention, Immune resilience.
  • The closest evidence on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).

The evidence for Krishna Tulsi in this product is insufficient to rate it reliably for generalized anxiety disorder, asthma, headache, respiratory tract infections, dental plaque, or diabetes. Katuki shows possibly effective evidence only for vitiligo; for other uses like asthma or hepatitis, the evidence is either possibly ineffective or too sparse to evaluate.

Neither ingredient has strong clinical backing for the immune support claimed on the label.

The evidence, ingredient by ingredient Holy Basil Picrorhiza

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Krishna Tulsi is generally well tolerated short-term in adults, though long-term safety data are limited. The most common side effects are loose stools and nausea — a small number of trial participants experienced these.

Katuki may cause vomiting, diarrhea, rash, itching, and dizziness, though human safety data are sparse. The safety data advise against Krishna Tulsi during pregnancy and while breastfeeding due to animal concerns and insufficient human evidence.

The same goes for Katuki — there isn't enough information to know it's safe in pregnancy or lactation. Talk with your doctor or pharmacist before taking this product if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Holy Basil Picrorhiza

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Picrorhiza, Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 331 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Essential Immune, check with your doctor or pharmacist if you're on immunosuppressants (Moderate risk — this product may interfere with them), blood thinners or antiplatelet drugs (Moderate risk of increased bleeding), diabetes medications (Moderate risk of low blood sugar), or pentobarbital (Moderate risk of increased sedation). No interactions are documented for Vana Tulsi, as we hold no data for it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Essential Immune combines two traditional herbs with limited clinical proof of benefit for immune support. If you take blood thinners, diabetes medications, or immunosuppressants, you'll want to check with your doctor or pharmacist before starting this — interactions are documented and may affect how your medications work.

Otherwise, most people tolerate it, though digestive upset is possible.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Essential Immune, straight from the product label.

Brand Organic India
Barcode (UPC) 801541519293
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 268099
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Essential Immune by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
801541519293
IngredientAmount% DV
organic Krishna Tulsi120 mg--
organic Vana Tulsi110 mg--
Katuki320 mg--

Other ingredients: organic Vegetable Pullulan Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

At the heart of organic India is our commitment to be a living embodiment of love and consciousness in action. Whole herb solutions grown sustainably by small family farmers using regenerative organic agriculture.

Mfg. Lic. No. A-2755

For export to USA only

Formula

Healthy conscious living Essential Immune is your go-to whole-herb formula for daily maintenance of healthy immune function. Offering a unique blend of ancient Ayurvedic herbs, this nourishing formula encourages your body's natural resilience and overall well-being.

Halal Mumbai India Halal Committee Registration No. 0854

OU (Kosher)

Pictured: Katuki flower

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules with food and water twice daily, not to exceed 4 capsules per day.

Precautions

Do not use if pregnant or nursing without consulting a physician.

Warning: Reproductive Harm - www.P65Warnings.ca.gov

Formulation

Vegan - Vegetarian

Gluten free

Daily Immune Support

Certified Organic by Control Union-CU 801983. Product produced and processed according to NPOP standard of India & USDA-NOP www.controlunion.com

Product of India

Non GMO

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation Control Union Certified NPOP/NAB/0010

Halal Mumbai India Halal Committee Registration No. 0854 OU (Kosher)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Essential Immune by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Essential Immune label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Essential Immune by Organic India

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Krishna Tulsi

Interacts with
212 drugs
120 mg per serving

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and p...

Organic Krishna Tulsi monograph & interactions

Organic Vana Tulsi

110 mg per serving

Katuki

Interacts with
207 drugs
320 mg per serving Form: Katuki, Katuki

Picrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints. Early lab and small h...

Katuki monograph & interactions

Other (inactive) ingredients: Organic Vegetable Pullulan Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Essential Immune by Organic India Drug Interactions

Want to check YOUR meds against Essential Immune?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
331Drugs
331 Moderate

Ingredients driving the most interactions

organic Krishna Tulsi 212
Katuki 207

Individual Drug Interactions

The ingredients in Essential Immune interact with 331 drugs. Click any drug to see the details.

2 of the 3 ingredients in Essential Immune interact with drugs. Each result below shows which ingredient is responsible. organic Krishna Tulsi Katuki

Each ingredient & the kinds of drugs it affects

For each ingredient in Essential Immune with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Krishna Tulsi3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
organic Krishna Tulsi full monograph & interactions

Katuki2 drug types · 207 drugs

Antidiabetes Drugs

Evidence from animal research suggests that an extract of picrorhiza can reduce fasting and non-fasting blood sugar levels. Theoretically, picrorhiza might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Immunosuppressants

Picrorhiza seems to have immunostimulating activity. Theoretically, picrorhiza may interfere with immunosuppressant therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).

Likelihood Possible Evidence D
Katuki full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Essential Immune, from the product label.

Organic India

See all Organic India products
Name
Organic India Pvt. Ltd.
Street Address
Factory: C-5/10, Agro Park Phase -II UPSIDC Industrial Area, Kursi Road
City
Barabanki
State
U.P.
ZipCode
225302
Pharmacist Counseling Corner

Essential Immune by Organic India: Common Questions

Does Essential Immune by Organic India interact with any medications?
Yes. Based on its ingredients, Essential Immune has a known interaction with 331 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Essential Immune contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against Essential Immune during pregnancy and while breastfeeding due to insufficient human evidence and animal concerns. Talk with your doctor or pharmacist about whether it's right for you in these situations.
What are the common side effects?
Loose stools and nausea are the most commonly reported side effects from Krishna Tulsi. Katuki may cause vomiting, diarrhea, rash, itching, and dizziness, though these are less commonly documented in humans.
Does this product actually boost immune function?
The clinical evidence for Krishna Tulsi and Katuki in supporting immune function isn't well established in the data we hold. Both ingredients are used in traditional medicine, but reliable evidence of benefit is limited.
Is this safe to take long-term?
Krishna Tulsi is generally well tolerated short-term in adults, but high-quality long-term safety data are limited. Katuki is used traditionally but has sparse human safety data overall. Talk with your doctor or pharmacist if you're considering long-term use.
What is Katuki?
Katuki is the common name for picrorhiza, an herb used in traditional medicine. In this product, it's included for its purported immune-supporting properties, though clinical evidence for most uses is thin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Essential Immune label
Go deeper

The Full Monographs Behind Essential Immune’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph → Herb & supplement monograph

Picrorhiza

Interacts with 207 drugs

Picrorhiza (Picrorhiza kurroa) is a bitter Himalayan herb used in Ayurvedic medicine, mainly for liver and digestive complaints. Early lab and small human studies suggest possible liver-prot...

Read the full Picrorhiza monograph →
Sources

Sources & How We Checked

Essential Immune's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Picrorhiza 7 references
  1. Sharma ML, Rao CS, Duda PL. Immunostimulatory activity of Picrorhiza kurroa leaf extract. J Ethnopharmacol 1994;41:185-92. PubMed
  2. Bedi KL, Zutshi U, Chopra CL, Amla V. Picrorhiza kurroa, an ayurvedic herb, may potentiate photochemotherapy in vitiligo. J Ethnopharmacol 1989;27:347-52. PubMed
  3. Vaidya AB, Antarkar DS, Doshi JC, et al. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studies. J Postgrad Med 1996;42:105-8.
  4. Baruah CC, Gupta PP, Nath A, et al. Anti-allergic and anti-anaphylactic activity of picroliv--a standardised iridoid glycoside fraction of Picrorhiza kurroa. Pharmacol Res 1998;38:487-92.
  5. Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. J Postgrad Med 1983;29:89-95.
  6. Joy, K. L. and Kuttan, R. Anti-diabetic activity of Picrorrhiza kurroa extract. J Ethnopharmacol 11-1-1999;67(2):143-148. PubMed
  7. Brockwell C, Ampikaipakan S, Sexton DW, Price D, Freeman D, Thomas M, Ali M, Wilson AM. Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2014;9:715-21. PubMed

See these in context on the Picrorhiza monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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