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Dietary supplement

Flora Iron Ingredients & Drug Interactions

by Flora

Liquid Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Flora Iron is a dietary supplement by Flora with 6 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 422 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B6, Niacin, Iron. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Flora Iron by Flora

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Flora Iron is a liquid containing six active ingredients: vitamin B6, vitamin B12, riboflavin, thiamine, niacin, and iron. Each plays a role in energy, red blood cell health, or oxygen transport.

The product also contains inactive ingredients—filtered water, orange juice concentrate, pineapple puree, molasses, spinach, anise, red beet crystals, acerola powder, ascorbic acid, and citric acid—which are excipients and flavorings.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Iron supplementation for nutritional support.
  • We looked for evidence on: Iron-deficiency anemia, Fatigue from iron deficiency.
  • The closest evidence on file: Iron is rated "Insufficient Reliable Evidence To Rate" for Fatigue (Natural Medicines).
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Fatigue.
  • Also on file: Thiamine is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

Vitamin B6 is effective for sideroblastic anemia and B6 deficiency, likely effective for high homocysteine, and possibly effective for pregnancy-related nausea. Vitamin B12 is effective for B12 deficiency and possibly effective for canker sores and nerve pain after shingles.

Thiamine is effective for thiamine deficiency and Wernicke-Korsakoff syndrome, possibly effective for menstrual pain. Niacin is likely effective for pellagra and possibly effective for acne, high phosphate, osteoarthritis, and diabetes.

Iron is effective for iron deficiency anemia and pregnancy-related iron deficiency, and possibly effective for heart failure. Riboflavin's effectiveness is not established in the data we hold.

The evidence, ingredient by ingredient Vitamin B6 Vitamin B12 Riboflavin Thiamine Niacinamide Iron

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B6 is generally well tolerated at standard doses but high doses over time can damage nerves; it's used for morning sickness under medical guidance only. Vitamin B12 is very safe—your body removes excess in urine and has no established upper limit.

Riboflavin and thiamine are very safe at recommended amounts; excess is removed. Niacin is usually well tolerated at recommended amounts, but high doses need supervision.

Iron is generally safe at appropriate doses, but excess is toxic; it should be used when there's a real need. Pregnancy and breastfeeding use should be guided by your healthcare provider for each ingredient.

Side effects, ingredient by ingredient Vitamin B6 Vitamin B12 Riboflavin Thiamine Niacinamide Iron

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Iron, Vitamin B12, Vitamin B6, Riboflavin, Thiamine, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
  • For scale: 422 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take blood pressure medications, blood thinners (warfarin), seizure drugs, heart rhythm medications, antibiotics (quinolone, tetracycline, or trimethoprim), levothyroxine (thyroid), levodopa (Parkinson's), metformin (diabetes), bisphosphonates (bone), methyldopa (blood pressure), mycophenolate (transplant), or penicillamine (Wilson's disease). Several of these carry Moderate-severity interactions with iron or B vitamins in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Flora Iron is a multi-B-vitamin and iron supplement aimed at supporting energy and red blood cell health. If you take any prescription medication—especially blood pressure drugs, seizure medications, blood thinners, antibiotics, thyroid medication, or Parkinson's medication—you'll need to check with your own doctor or pharmacist before starting, because the iron and B vitamins here interact with several drug classes.

Talk it over with your healthcare provider to make sure it's right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flora Iron, straight from the product label.

Brand Flora
Barcode (UPC) 061998647424
Net contents 15 Fluid Ounce(s); 445 mL
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 265038
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flora Iron by Flora, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 mL
Maximum serving Sizes:
10 mL
Servings per container
44
UPC/BARCODE
061998647424
IngredientAmount% DV
Vitamin B61.3 mg76%, 65%
Vitamin B122.4 mcg100%, 86%
Riboflavin1.1 mg85%, 69%
Thiamine1.1 mg92%, 79%
Calories10 Calorie(s)--
Total Sugars2 NP--
added Sugars1 Gram(s)2%, 2%
Total Carbohydrates2 Gram(s)1%, 1%
Niacin8 mg50%, 44%
Iron9 mg50%, 33%

Other ingredients: filtered Water, Orange juice concentrate, Pineapple Puree, Molasses, Spinach, Anise, Red Beet, Crystals, Acerola, Powder, Ascorbic Acid, Citric Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Shake bottle gently before use. A measuring cup is provided. Take with food, a few hours before or after taking other medications or supplements. Adults (including pregnant and lactating women) and adolescents age 14+: Take 2 teaspoons (10 mL) twice daily. Adolescents and children (age 4-13): Take 2 teaspoons (10 mL) once daily.

Storage

Store unopened bottle at room temperature. Keep refrigerated at all times after opening and consume within 4 weeks.

To preserve the product, return the bottle to the refrigerator after use. After initial opening, replace with child resistant cap.

Formulation

This product contains neither alcohol nor preservatives.

Supports healthy iron and energy levels Supports healthy red blood cell production Easily absorbed + non-constipating + Vegan + yeast & gluten-free

Easily absorbed + non-constipating + Vegan + yeast & gluten-free

Easily absorbed + non-constipating + Vegan + yeast & gluten-free

Liquid formula

Precautions

Keep out of reach of children.

Liquid iron may in some instances cause surface staining to teeth. Rinse mouth with water, or brush teeth immediately after consuming. Cautions: Stop use if hypersensitivity occurs.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Security sealed for your protection. Do not use if seal is missing or damaged.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

With B-Vitamin complex

Kosher Check

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Kosher Check

See for yourself

Flora Iron by Flora label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Flora Iron by Flora

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size10 mL Dosage formLiquid Servings per container44 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
1.3 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Vitamin B12

Interacts with
20 drugs
2.4 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Riboflavin

Interacts with
20 drugs
1.1 mg per serving Form: Vitamin B2

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Thiamine

Interacts with
3 drugs
1.1 mg per serving Form: Thiamine Hydrochloride, Vitamin B1

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Niacin

Interacts with
124 drugs
8 mg per serving Form: Niacinamide

Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products. It is well established for preventing and t...

Niacin monograph & interactions

Iron

Interacts with
80 drugs
9 mg per serving Form: Ferrous Gluconate

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...

Iron monograph & interactions

Other (inactive) ingredients: Filtered Water, Orange juice concentrate, Pineapple Puree, Molasses, Spinach, Anise, Red Beet, Crystals, Acerola, Powder, Ascorbic Acid, Citric Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flora Iron by Flora Drug Interactions

Want to check YOUR meds against Flora Iron?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
422Drugs
398 Moderate 24 Minor

Ingredients driving the most interactions

Niacin 124
Iron 80

Each ingredient & the kinds of drugs it affects

For each ingredient in Flora Iron with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D

Niacin4 drug types · 124 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, niacinamide may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on hemodialysis.
Several cases of thrombocytopenia have been reported for hemodialysis patients treated with niacinamide 1 gram daily. Hemodialysis patients receiving niacinamide had almost a three-fold higher risk of developing thrombocytopenia when compared with those receiving placebo.

Likelihood Unlikely Evidence D
Carbamazepine (Tegretol)

Niacinamide might increase the levels and adverse effects of carbamazepine.
Plasma levels of carbamazepine were increased in two children given high-dose niacinamide, 60-80 mg/kg/day. This might be due to inhibition of the cytochrome P450 enzymes involved in carbamazepine metabolism. There is not enough data to determine the clinical significance of this interaction.

Likelihood Possible Evidence D
Primidone (Mysoline)

Niacinamide might increase the levels and adverse effects of primidone.
Case reports in children suggest niacinamide 60-100 mg/kg/day reduces hepatic metabolism of primidone to phenobarbital, and reduces the overall clearance rate of primidone; however, there is not enough data to determine the clinical significance of this potential interaction.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that niacinamide may increase the anticoagulant effects of warfarin.
In a case report, a patient on warfarin developed an elevated international normalized ratio (INR) of 8.4 after taking niacinamide 500 mg twice daily for 10 days. The patient's INR was previously stable, ranging between 2 and 3, with no other changes to current medications or diet reported. The elevated INR returned to the therapeutic range after receiving vitamin K and discontinuing niacinamide.

Likelihood Possible Evidence D

Iron13 drug types · 80 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.

Likelihood Probable Evidence D
Bisphosphonates

Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D
Denosumab (Prolia, Others)

Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.

Likelihood Possible Evidence D
Dolutegravir (Tivicay)

Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.

Likelihood Probable Evidence B
Integrase Inhibitors

Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.

Likelihood Possible Evidence D
Levodopa

Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence B
Methyldopa (Aldomet)

Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.

Likelihood Probable Evidence B
Mycophenolate Mofetil (Cellcept)

Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.

Likelihood Unlikely Evidence D
Penicillamine (Cuprimine, Depen)

Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.

Likelihood Probable Evidence D
Quinolone Antibiotics

Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.

Likelihood Probable Evidence D
Chloramphenicol

Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.

Likelihood Unlikely Evidence D

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Flora Iron, from the product label.

Flora

See all Flora products
Name
Flora, Inc.
Street Address
805 E. Badger Rd.
City
Lynden
State
WA
ZipCode
98264
Phone Number
1.800.446.2110
Web Address
www.florahealth.com
Pharmacist Counseling Corner

Flora Iron by Flora: Common Questions

Does Flora Iron by Flora interact with any medications?
Yes. Based on its ingredients, Flora Iron has a known interaction with 422 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flora Iron contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Flora Iron if I'm pregnant?
Vitamin B6 is rated Likely Safe and Possibly Unsafe in pregnancy, so it needs guidance from your prenatal provider. Vitamin B12, riboflavin, thiamine, niacin, and iron are rated Likely Safe in pregnancy. Talk with your doctor or midwife before starting to make sure the doses are right for you.
Is it safe while breastfeeding?
Vitamin B12, riboflavin, thiamine, and niacin are all considered safe at recommended amounts while breastfeeding. Vitamin B6 and iron are also considered acceptable, but check with your provider about the specific doses in this product.
What are the most common side effects?
Vitamin B6 may cause abdominal pain, headache, or nausea at standard doses. Iron commonly causes constipation, diarrhea, nausea, or abdominal pain. Riboflavin may cause nausea and bright yellow urine at higher doses. Thiamine rarely causes allergic reactions. Most side effects are mild and dose-related.
Why are there 10 inactive ingredients listed?
The inactive ingredients—water, juice concentrate, puree, molasses, spinach, anise, beet crystals, acerola powder, and citric acid—are flavorings, sweeteners, and processing aids that make the liquid form palatable and stable. They don't add therapeutic benefit.
Can high doses of the vitamins in this product cause harm?
Yes. Vitamin B6 at very high doses and over long periods can cause nerve damage. Niacin at high doses may cause gastrointestinal upset and skin problems. Iron excess is toxic and should only be taken when there's a real deficiency. Stick to recommended amounts unless your doctor advises otherwise.
Does this product work for iron deficiency anemia?
Iron in this product is effective for iron deficiency anemia, but only if you actually have a deficiency. Diagnosis and dosing should be guided by your doctor—taking iron without a confirmed deficiency isn't helpful and can be harmful.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flora Iron is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flora Iron label
Go deeper

The Full Monographs Behind Flora Iron’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph →
Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph →
Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph →
Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph →
Herb & supplement monograph

Niacinamide

Interacts with 124 drugs

Niacinamide (also called nicotinamide) is a form of vitamin B3 used in supplements and skin-care products. It is well established for preventing and treating vitamin B3 deficiency, and there...

Read the full Niacinamide monograph →
Herb & supplement monograph

Iron

Interacts with 80 drugs

Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...

Read the full Iron monograph →
Sources

Sources & How We Checked

Flora Iron's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 168 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
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Vitamin B12 30 references
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Riboflavin 5 references
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Thiamine 7 references
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Niacinamide 22 references
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Iron 72 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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