Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

FloraMORE Ingredients & Drug Interactions

by Renew Life

FloraMORE label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FloraMORE against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

FloraMORE is a dietary supplement by Renew Life with 4 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 402 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Probiotic 12 Billion Blend, N-Acetyl-D-Glucosamine, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against FloraMORE by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with FloraMORE by Renew Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of FloraMORE by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 11 active ingredients.
  • “Lactobacillus plantarum” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Bifidobacterium breve” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Probiotic 12 Billion Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

FloraMORE contains 11 active ingredients focused on digestive and gut health. The main components are probiotics — beneficial bacteria strains including Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium animalis lactis, Bifidobacterium longum, Lactobacillus acidophilus, Bifidobacterium breve, and Lactobacillus casei — plus L-Glutamine (an amino acid that supports gut function), N-Acetyl-D-Glucosamine (a compound that supports joint and digestive lining health), and FOS (a prebiotic fiber that feeds beneficial bacteria).

The capsule also contains inactive ingredients: vegetable capsule material, rice bran, and ascorbyl palmitate (a form of vitamin C used as a preservative).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote balanced intestinal environment.
  • We looked for evidence on: Antibiotic-associated diarrhea, Diarrhea, Constipation, Colic, Clostridioides difficile infection, Crohn disease — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Helicobacter pylori.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Crohn disease, Radiation-induced diarrhea.

The effectiveness of FloraMORE's ingredients varies by condition. Lactobacillus acidophilus shows promise for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-related diarrhea, and bacterial vaginosis — all rated Possibly Effective.

N-Acetyl-D-Glucosamine is Likely Effective for osteoarthritis. For most other claimed uses — including age-related cognitive decline, hay fever, anxiety, asthma, and athletic performance — the evidence we hold is rated Insufficient Reliable Evidence To Rate or shows no benefit.

L-Glutamine is Possibly Effective for sickle cell disease and possibly for HIV-related wasting and recovery after surgery, though these aren't typical uses for a probiotic blend.

The evidence, ingredient by ingredient Glutamine Glucosamine Lactobacillus Acidophilus Bifidobacterium Longum Bifidobacterium Breve

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in healthy adults. L-Glutamine can cause gastrointestinal side effects — bloating, constipation, diarrhea, nausea, and flatulence — especially at higher doses; people with kidney or liver disease should use it only under medical supervision.

The probiotics (Bifidobacterium longum and Lactobacillus acidophilus) are generally well tolerated but carry rare risks in people who are seriously ill or immune-compromised; they may rarely cause abdominal discomfort, bloating, or flatulence. N-Acetyl-D-Glucosamine is well tolerated but may rarely cause allergic reactions — including rash, itching, or in rare cases more severe reactions — and may trigger asthma in sensitive individuals.

For pregnancy, L-Glutamine and the probiotics are rated Likely or Possibly Safe, but N-Acetyl-D-Glucosamine should be avoided in pregnancy and breastfeeding due to insufficient safety data.

Side effects, ingredient by ingredient Glutamine Glucosamine Lactobacillus Acidophilus Bifidobacterium Longum Bifidobacterium Breve

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Lactobacillus Acidophilus, Glucosamine, Glutamine, Bifidobacterium Longum.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 402 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking FloraMORE, check with your doctor or pharmacist if you take warfarin or other blood thinners (Major risk from N-Acetyl-D-Glucosamine), anticonvulsants (Moderate risk from L-Glutamine), antibiotics (Moderate risk from the probiotics — you may need to space them apart), cancer chemotherapy drugs like etoposide or doxorubicin (Moderate risk), diabetes medications (Minor risk), or acetaminophen regularly (Minor risk). These are the medication types with documented interactions in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

FloraMORE is mainly a probiotic and gut-support formula, with the strongest evidence for Lactobacillus acidophilus in IBS, diarrhea, and related conditions. It's generally well tolerated, but if you take warfarin, anticonvulsants, antibiotics, chemotherapy, diabetes medications, or acetaminophen regularly, check with your own doctor or pharmacist before starting — the interactions documented here are real and may affect how your medications work.

Those who are pregnant, breastfeeding, seriously ill, or immune-compromised should also talk it over with their healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FloraMORE, straight from the product label.

Brand Renew Life
Barcode (UPC) 631257527608
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 247418
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FloraMORE by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
631257527608
IngredientAmount% DV
L-Glutamine80 mg--
Lactobacillus plantarum0 NP--
Lactobacillus rhamnosus0 NP--
Bifidobacterium animalis lactis0 NP--
Bifidobacterium longum0 NP--
Lactobacillus acidophilus0 NP--
Bifidobacterium breve0 NP--
Lactobacillus casei0 NP--
FOS100 mg--
N-Acetyl-D-Glucosamine20 mg--
Probiotic 12 Billion Blend0 NP--
Total Lacto Probiotic Cultures0 NP--
Total Bifido Probiotic Cultures0 NP--
Total Lacto/Bifido Probiotic Cultures0 NP--

Other ingredients: Vegetable Capsule, Rice Bran, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

FloraMORE is a daily probiotic with 7 strains of microflora and added ingredients to promote a balanced intestinal environment. L-glutamine and NAG nourish and support a healthy intestinal lining. FOS promotes the growth of beneficial bacteria in the digestive tract.

12 Billion live cultures per capsule

Formulation

Gluten Free Soy Free No Artificial Ingredients

Quality, purity, and potency guaranteed through expiration.

Manufactured in USA in a GMP Facility.

Digestive Probiotic Blend

Probiotics plus digestive support Supports Overall Digestive Health Balances Digestive System Promotes a Healthy Intestinal Lining

Gluten Free

Storage

Store in a cool, dry place at 77 degrees F (25 degrees C) or below. Best if refrigerated.

Precautions

Keep out of reach of children.

Consult your healthcare professional before using this or any product if you are pregnant, nursing, or under medical supervision.

Tamper Evident: Do not use if safety seal under cap is broken or missing.

Contains an ingredient derived from crustacean shells (shrimp, lobster, crab).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Probiotic Supplement

General Statements

Renew Life The digestive care experts

Suggested/Recommended/Usage/Directions

Directions: Take one capsule daily with or without food.

Brand IP Statement(s)

Patent #US 6,468,525 B1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FloraMORE by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FloraMORE label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FloraMORE by Renew Life

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
80 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

FOS

100 mg per serving

N-Acetyl-D-Glucosamine

Interacts with
170 drugs
20 mg per serving

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...

N-Acetyl-D-Glucosamine monograph & interactions

Probiotic 12 Billion Blend

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic 12 Billion Blend monograph & interactions

Other (inactive) ingredients: Vegetable Capsule, Rice Bran, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

FloraMORE by Renew Life Drug Interactions

Want to check YOUR meds against FloraMORE?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
402Drugs
2 Major 245 Moderate 155 Minor

Ingredients driving the most interactions

Probiotic 12 Billion Blend 182
N-Acetyl-D-Glucosamine 170
L-Glutamine 50

Individual Drug Interactions

The ingredients in FloraMORE interact with 402 drugs. Click any drug to see the details.

3 of the 4 ingredients in FloraMORE interact with drugs. Each result below shows which ingredient is responsible. Probiotic 12 Billion Blend N-Acetyl-D-Glucosamine L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in FloraMORE with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic 12 Billion Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic 12 Billion Blend full monograph & interactions

N-Acetyl-D-Glucosamine4 drug types · 170 drugs

Warfarin (Coumadin)

Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.

Likelihood Probable Evidence D
Topoisomerase Ii Inhibitors

Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.

Likelihood Possible Evidence B
Antidiabetes Drugs

Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.

Likelihood Unlikely Evidence B
N-Acetyl-D-Glucosamine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FloraMORE, from the product label.

Renew Life

Name
Renew Life Formulas
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Pharmacist Counseling Corner

FloraMORE by Renew Life: Common Questions

Does FloraMORE by Renew Life interact with any medications?
Yes. Based on its ingredients, FloraMORE has a known interaction with 402 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FloraMORE contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does FloraMORE work for IBS or diarrhea?
The Lactobacillus acidophilus in FloraMORE is rated Possibly Effective for irritable bowel syndrome, antibiotic-related diarrhea, and bacterial vaginosis. That's the strongest evidence we have for any condition this product addresses, though results vary by individual.
Can I take FloraMORE with antibiotics?
Not at the same time. Since the probiotics contain live organisms, antibiotics will kill them and defeat the purpose. Separate the doses — ask your doctor or pharmacist for a specific timing plan that works for your antibiotic.
What side effects might I get from L-Glutamine?
Gastrointestinal effects are most common: bloating, constipation, diarrhea, nausea, and flatulence. These tend to be mild, especially at lower doses. If you have kidney or liver disease, use this product only under your doctor's supervision.
Is it safe to take FloraMORE while pregnant?
L-Glutamine and the probiotics are rated Likely or Possibly Safe in pregnancy, but N-Acetyl-D-Glucosamine should be avoided — there isn't enough safety data. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy.
Can I take FloraMORE if I'm on warfarin?
The N-Acetyl-D-Glucosamine in this product may increase warfarin's blood-thinning effects and raise your bleeding risk. Do not start FloraMORE without checking with your doctor first — this is a Major interaction.
What are the inactive ingredients?
The capsule contains vegetable capsule material, rice bran, and ascorbyl palmitate (a form of vitamin C used as a preservative). There are no other fillers listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FloraMORE label
Go deeper

The Full Monographs Behind FloraMORE’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Glucosamine

Interacts with 170 drugs

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...

Read the full Glucosamine monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph →
Sources

Sources & How We Checked

FloraMORE's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 114 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
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See these in context on the Lactobacillus Acidophilus monograph →

Bifidobacterium Breve 9 references
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See these in context on the Bifidobacterium Breve monograph →

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See these in context on the Glucosamine monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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