Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

FloraMore Ingredients & Drug Interactions

by Renew Life

FloraMore label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FloraMore against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

FloraMore is a dietary supplement by Renew Life with 5 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 402 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Probiotic 12 Billion Blend, N-Acetyl D-Glucosamine, L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against FloraMore by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with FloraMore by Renew Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of FloraMore by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 3 of its 11 active ingredients.
  • “Probiotic 12 Billion Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.

FloraMore contains 11 active ingredients centered on digestive and gut health support. The formula includes L-Glutamine, an amino acid; N-Acetyl D-Glucosamine, a compound that supports joint and digestive tissue; FOS (fructooligosaccharides), a prebiotic fiber; and a probiotic blend of 12 billion live cultures per serving.

That blend is made up of Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus plantarum, and three Bifidobacterium species—longum, bifidum, and breve—all designed to support your intestinal flora. The capsule itself is made from vegetable material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: healthy intestinal lining and digestive bacteria.
  • We looked for evidence on: Antibiotic-associated diarrhea, Chemotherapy-induced diarrhea, Clostridioides difficile infection, Colic, Constipation, Crohn disease — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Ineffective" for Crohn disease, Radiation-induced diarrhea.
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Radiation-induced diarrhea, Rotaviral diarrhea, Travelers' diarrhea.

The evidence for this product's ingredients is mixed. L-Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting and recovery after surgery.

N-Acetyl D-Glucosamine is likely effective for osteoarthritis but has insufficient evidence for back pain, aging skin, and liver health. Among the probiotics, Lactobacillus acidophilus and Bifidobacterium bifidum are possibly effective for irritable bowel syndrome, and L. acidophilus is also possibly effective for antibiotic-associated diarrhea and bacterial vaginosis.

Most other probiotic strains in the formula have insufficient evidence to rate their effectiveness for the conditions studied. The evidence is strongest for the formula's use in gut health and IBS support, but weaker for other potential benefits.

The evidence, ingredient by ingredient Glutamine Lactobacillus Acidophilus Bifidobacterium Longum Bifidobacterium Bifidum Bifidobacterium Breve Glucosamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated in healthy adults, though people with kidney or liver disease should use it only under medical supervision. The most common side effects are gastrointestinal—belching, bloating, constipation, diarrhea, flatulence, and nausea—plus headache and musculoskeletal pain.

Rare cases of dizziness and mania have been reported in people with bipolar disorder taking high doses. N-Acetyl D-Glucosamine is generally well tolerated, with similar gastrointestinal side effects (bloating, constipation, diarrhea, nausea, heartburn, and cramps).

There is concern about allergic reactions in sensitive people; one Australian safety review found 72% of reported adverse events involved hypersensitivity reactions, ranging from mild itching and rashes to severe reactions including anaphylaxis. Cases of asthma exacerbation have also been reported.

Pregnancy safety data advise against use during pregnancy, and breastfeeding safety is not well studied—avoid unless your doctor advises otherwise. The probiotics (L. acidophilus, Bifidobacterium species) are generally well tolerated in healthy adults and children, with gastrointestinal side effects (bloating, flatulence, abdominal pain, diarrhea) being uncommon.

Rare cases of infection have been reported in critically ill or immunocompromised patients. L. acidophilus is possibly safe in pregnancy, but breastfeeding data are limited.

Side effects, ingredient by ingredient Glutamine Lactobacillus Acidophilus Bifidobacterium Longum Bifidobacterium Bifidum Bifidobacterium Breve Glucosamine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Lactobacillus Acidophilus, Glucosamine, Glutamine, Bifidobacterium Breve, Bifidobacterium Bifidum, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 402 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking FloraMore, double-check with your own doctor or pharmacist if you take warfarin or other blood thinners—N-Acetyl D-Glucosamine can significantly increase bleeding risk. Next, if you take antibiotics, separate them from this product (ask your pharmacist for the right timing), because the live probiotic cultures may be killed, reducing their benefit.

If you take cancer chemotherapy drugs like etoposide or doxorubicin, seizure medications, or diabetes drugs, confirm the fit with your healthcare provider, as glucosamine and glutamine carry documented interactions with each.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

FloraMore is a broad-spectrum digestive formula best suited for people looking to support gut health, IBS symptoms, or recovery from antibiotic use, particularly through its probiotic blend and L-Glutamine content. If you take warfarin, antibiotic medications, cancer chemotherapy, seizure medications, or diabetes drugs, talk with your own doctor or pharmacist before starting—the interactions are real and may require timing adjustments or monitoring.

People with kidney or liver disease, allergies to shellfish (glucosamine source), severe immune compromise, or those pregnant or breastfeeding should check with their healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FloraMore, straight from the product label.

Brand Renew Life
Barcode (UPC) 631257527202
Net contents 120 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2017
DSLD ID 71508
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FloraMore by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
120
UPC/BARCODE
631257527202
IngredientAmount% DV
L-Glutamine100 mg--
FOS120 mg--
Probiotic 12 Billion Blend200 mg--
N-Acetyl D-Glucosamine25 mg--
Lactobacillus acidophilus0 NP--
Total Cultures:0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus casei0 NP--
Bifidobacterium longum0 NP--
Bifidobacterium bifidum0 NP--
Bifidobacterium breve0 NP--
Lactobacillus plantarum0 NP--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Patent # US 6,468,525 B1

Renew Life The digestive care company

Floramore is a daily probiotic with 7 strains of microflora and added ingredients to promote a balanced intestinal environment.

Precautions

This product contains an ingredient derived from crustacean shells (shrimp, lobster, crab). This product may contain mild traces of milk proteins from fermentation ingredients.

Keep out of reach of children.

Warning: Consult your physician before using this or any product if you are pregnant, nursing, trying to conceive, taking medication or have a medical condition.

Tamper Evident: Do not use if safety seal is broken or missing.

Formula

This product may contain mild traces of milk proteins from fermentation ingredients.

Manufactured in a GMP and Kosher facility

Suggested/Recommended/Usage/Directions

Directions: Take 1-2 capsules per day with meals.

General Statements

L-glutamine and NAG nourish and support a healthy intestinal lining. FOS promotes the growth of beneficial bacteria in the digestive tract.

Quality and purity guaranteed

Made in USA

Digestive probiotic blend 12 billion

Probiotics plus digestive support

Supports overall digestive health Helps enhance immune function Promotes a healthy intestinal lining

Formulation

Contains no yeast, wheat, corn, soy, gluten, salt, binders, fillers or artificial ingredients

Gluten-free

Storage

Best if refrigerated after opening.

General

0110

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FloraMore by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FloraMore label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FloraMore by Renew Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutamine

Interacts with
50 drugs
100 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

FOS

120 mg per serving

Probiotic 12 Billion Blend

Interacts with
182 drugs
200 mg per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic 12 Billion Blend monograph & interactions

N-Acetyl D-Glucosamine

Interacts with
170 drugs
25 mg per serving

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...

N-Acetyl D-Glucosamine monograph & interactions

Total Cultures:

0 NP per serving

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

FloraMore by Renew Life Drug Interactions

Want to check YOUR meds against FloraMore?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
402Drugs
2 Major 245 Moderate 155 Minor

Ingredients driving the most interactions

Probiotic 12 Billion Blend 182
N-Acetyl D-Glucosamine 170
L-Glutamine 50

Individual Drug Interactions

The ingredients in FloraMore interact with 402 drugs. Click any drug to see the details.

3 of the 5 ingredients in FloraMore interact with drugs. Each result below shows which ingredient is responsible. Probiotic 12 Billion Blend N-Acetyl D-Glucosamine L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in FloraMore with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic 12 Billion Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic 12 Billion Blend full monograph & interactions

N-Acetyl D-Glucosamine4 drug types · 170 drugs

Warfarin (Coumadin)

Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.

Likelihood Probable Evidence D
Topoisomerase Ii Inhibitors

Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.

Likelihood Possible Evidence B
Antidiabetes Drugs

Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.

Likelihood Unlikely Evidence B
N-Acetyl D-Glucosamine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FloraMore, from the product label.

Renew Life

Name
Renew Life Formulas
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.renewlife.com
Pharmacist Counseling Corner

FloraMore by Renew Life: Common Questions

Does FloraMore by Renew Life interact with any medications?
Yes. Based on its ingredients, FloraMore has a known interaction with 402 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FloraMore contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take FloraMore while I'm on antibiotics?
Not at the same time. The antibiotics will kill the live probiotic cultures in this product, making them ineffective. Ask your pharmacist how long to space them apart—typically at least 2 hours, though sometimes longer depending on the antibiotic. Once you finish your course, you can resume the probiotics.
Is FloraMore safe if I'm pregnant or breastfeeding?
L-Glutamine is considered likely safe in pregnancy, and some of the probiotics (like L. acidophilus and B. longum) are possibly safe. However, N-Acetyl D-Glucosamine should be avoided in pregnancy, and breastfeeding safety data are limited for several ingredients. Talk with your doctor or pharmacist about whether this formula is right for you during pregnancy or lactation.
What are the most common side effects?
Gastrointestinal upset is the main concern: bloating, gas, constipation, diarrhea, nausea, and abdominal discomfort. These tend to be mild and often improve as your gut adjusts. If you have a history of allergic reactions or asthma, mention that to your doctor—rare cases of allergic reactions to glucosamine have been reported.
Does FloraMore work for IBS?
Two of the probiotics in this formula—Lactobacillus acidophilus and Bifidobacterium bifidum—are possibly effective for IBS. The overall evidence is mixed, so results vary from person to person. Give it a reasonable trial (several weeks) and track your symptoms with your doctor.
Can I take this with my blood thinner (warfarin)?
No—not without checking with your doctor first. The N-Acetyl D-Glucosamine in FloraMore can increase warfarin's blood-thinning effect and raise your bleeding risk. Your prescriber may want to monitor your INR (blood clotting time) more closely or adjust your dose if you decide to take it together.
What's in the vegetable capsule?
The capsule is a plant-based shell that holds the active ingredients. The inactive ingredients list only shows the capsule itself—there are no fillers, binders, or other additives listed separately.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FloraMore label
Go deeper

The Full Monographs Behind FloraMore’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Bifidobacterium Breve

Interacts with 182 drugs

Bifidobacterium breve is a 'friendly' gut bacterium taken as a probiotic, most often to support digestion and balance the gut microbiome. Some studies suggest possible benefits for certain d...

Read the full Bifidobacterium Breve monograph → Herb & supplement monograph

Glucosamine

Interacts with 170 drugs

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...

Read the full Glucosamine monograph →
Sources

Sources & How We Checked

FloraMore's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 121 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Glucosamine 58 references
  1. Adams ME. Hype about glucosamine. Lancet 1999;354:353-4. PubMed
  2. Balkan B, Dunning BE. Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats. Diabetes 1994;43:1173-9. PubMed
  3. Giaccari A, Morviducci L, Zorretta D, et al. In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia. Diabetologia 1995;38:518-24. PubMed
  4. Holmang A, Nilsson C, Niklasson M, et al. Induction of insulin resistance by glucosamine reduces blood flow but not interstitial levels of either glucose or insulin. Diabetes 1999;48:106-11. PubMed
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Bifidobacterium Longum 21 references
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Bifidobacterium Bifidum 7 references
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Bifidobacterium Breve 9 references
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