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Dietary supplement

Full Spectrum Astragalus Extract Ingredients & Drug Interactions

by Planetary Herbals

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Full Spectrum Astragalus Extract is a dietary supplement by Planetary Herbals with 1 active ingredient. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus root (premium grade) liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Full Spectrum Astragalus Extract by Planetary Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a liquid extract containing one active ingredient: astragalus root (premium grade). The extract also contains grain alcohol and purified water as inactive ingredients to preserve and deliver the herbal material.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astragalus product and its label doesn't state a use — see Astragalus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for astragalus is not established in the data we hold. The product facts list six conditions—allergic rhinitis (hay fever), amenorrhea, aplastic anemia, angina, asthma, and beta-thalassemia—but each carries a rating of insufficient reliable evidence.

That means human studies haven't yet provided solid proof that astragalus works for these uses. If you're considering it for a specific condition, talk it over with your doctor or pharmacist.

The evidence, ingredient by ingredient Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated in the short term in healthy adults, though quality human safety data is limited. The facts advise against it during pregnancy and while breastfeeding because there isn't enough reliable safety data to know either way.

In clinical trials and studies, astragalus has been associated with dizziness in some cases, and intravenous forms have occasionally caused rash, eczema, and itching. However, these effects may not have been caused by astragalus itself, so the actual risk is unclear.

Side effects, ingredient by ingredient Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take immunosuppressants, cyclophosphamide (Cytoxan), lithium, or antidiabetes medications. Astragalus may reduce how well immunosuppressants and chemotherapy work, raise lithium levels, and increase your risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astragalus extract may work for some uses, but the evidence isn't solid yet. It's generally well tolerated short-term in healthy adults, but it does interact with immunosuppressants, lithium, certain chemotherapy drugs, and blood sugar medications—sometimes significantly.

If you take any prescription medication, check with your own doctor or pharmacist before starting, especially if you manage diabetes, take lithium, or use immune-modifying drugs. Avoid it if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Astragalus Extract, straight from the product label.

Brand Planetary Herbals
Barcode (UPC) 021078104643
Net contents 1 fl. Oz.; 29.57 mL
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80911
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Astragalus Extract by Planetary Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1.14 mL
Servings per container
29
UPC/BARCODE
021078104643
IngredientAmount% DV
Astragalus root (premium grade) liquid extract1 mL--

Other ingredients: Grain Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

General Statements

Approved by Michael Tierra L.Ac, O.M.D

Suggested/Recommended/Usage/Directions

Suggested Use: 35 to 40 drops twice daily.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if tamper-evident seal is broken or missing.

Keep out of the reach of children.

General

PF0464 REV A132

See for yourself

Full Spectrum Astragalus Extract by Planetary Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Full Spectrum Astragalus Extract by Planetary Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container29 Amounts shown are per serving.

1 mL per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus root (premium grade) liquid extract monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Astragalus Extract by Planetary Herbals Drug Interactions

Want to check YOUR meds against Full Spectrum Astragalus Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Astragalus Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus root (premium grade) liquid extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Full Spectrum Astragalus Extract, from the product label.

Planetary Herbals

See all Planetary Herbals products
Name
Planetary Herbals, LLC
Street Address
P.O. Box 1760
City
Soquel
State
CA
ZipCode
95073
Web Address
www.planetaryherbals.com
Pharmacist Counseling Corner

Full Spectrum Astragalus Extract by Planetary Herbals: Common Questions

Does Full Spectrum Astragalus Extract by Planetary Herbals interact with any medications?
Yes. Based on its ingredients, Full Spectrum Astragalus Extract has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Astragalus Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is astragalus safe during pregnancy or while breastfeeding?
No. The safety data isn't sufficient, so the facts advise against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about what's right for you.
What are the side effects I might experience?
Astragalus is generally well tolerated in the short term. In some clinical studies, dizziness has been reported, and intravenous forms have occasionally caused rash, eczema, or itching—though these effects may not have been caused by astragalus itself. Reliable safety data in humans is limited.
Does astragalus actually work for allergies, asthma, or other conditions listed here?
The evidence isn't established. The conditions listed—hay fever, asthma, amenorrhea, aplastic anemia, angina, and beta-thalassemia—all carry a rating of insufficient reliable evidence, meaning human studies haven't proven astragalus works for them yet.
What's the difference between the extract and whole root?
This product is a liquid extract, which means the active compounds from astragalus root have been concentrated and dissolved in alcohol and water for easier absorption. The product facts don't specify how it compares to whole root forms.
Can I take this if I have diabetes?
Check with your doctor or pharmacist first. Astragalus may lower blood sugar, and combining it with antidiabetes drugs could increase your risk of low blood sugar.
Can I take this with my antidepressant or other psychiatric medication?
The product facts don't document interactions with antidepressants or psychiatric drugs. Still, check with your pharmacist before adding any supplement, especially if you take multiple medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Astragalus Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Astragalus Extract label
Go deeper

The Full Monographs Behind Full Spectrum Astragalus Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Full Spectrum Astragalus Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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