Gaba- S Ingredients & Drug Interactions
by Nutri-West
What is this page for?
First and foremost: checking Gaba- S against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gaba- S is a dietary supplement by Nutri-West with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gaba- S by Nutri-West
Ask about any prescription or over-the-counter medication and we check it for interactions with Gaba- S by Nutri-West — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gaba- S by Nutri-West
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Nutri-West Gaba-S is a single-ingredient supplement containing GABA (gamma-aminobutyric acid), a naturally occurring compound in your brain that plays a role in relaxation and nerve signaling. The product contains 1 active ingredient with no inactive fillers or other ingredients listed.
Does it work?
Couldn't assess
The evidence for GABA supplementation is insufficient across the uses that have been studied — anxiety, ADHD, athletic performance, chronic bronchitis, and cerebral palsy all lack reliable evidence to show whether it works. We hold no data on other possible uses.
If you're considering GABA for a specific concern, it's worth discussing with your doctor or pharmacist whether the evidence supports it for your situation.
How safe is it?
Well-documented data
GABA appears to be generally well tolerated when taken by mouth short-term, though long-term safety hasn't been well studied. The most commonly reported side effects in trials were drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea.
One case of temporary amenorrhea (loss of menstruation) was reported in a patient taking GABA with another supplement. There isn't enough safety information to recommend GABA during pregnancy, and the available data advises against use while breastfeeding.
Talk with your doctor or pharmacist about whether it's appropriate for you.
Meds to double-check
Moderate interaction found
Before taking Nutri-West Gaba-S, double-check if you're on blood pressure medications (antihypertensives) — GABA may lower your pressure further. Also check if you take central nervous system depressants like prescription sleep aids, sedatives, or pain medications, as GABA may add to their sedative effects.
Run your medications through the search tool on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
GABA is a single-ingredient supplement that appears generally well tolerated in the short term, but evidence for its effectiveness is lacking across studied uses. If you take blood pressure medication or sedatives, check with your doctor or pharmacist before starting, as GABA may enhance their effects.
Long-term safety is unclear, so this is worth discussing with your healthcare provider before use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gaba- S, straight from the product label.
| Brand | Nutri-West |
|---|---|
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 25, 2013 |
| DSLD ID | 27712 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gaba- S by Nutri-West, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| GABA | 250 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Contains no starch, salt, sugar, wheat, corn, yeast, soy, milk, or preservatives.
Storage
Store in cool, dry place.
Precautions
KEEP OUT OF REACH OF CHILDREN.
TAMPER RESISTANT OUTER SEAL - DO NOT USE IF BROKEN.
FDA Statement of Identity
Dietary Supplement
General Statements
"When You Want The Best"
0080 MGF01/2010
FOR DISTRIBUTION BY HEALTH CARE PROFESSIONALS ONLY.
Suggested/Recommended/Usage/Directions
Directions for use: One tablet daily, or as directed.
General
Product # 1297
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gaba- S by Nutri-West label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gaba- S by Nutri-West
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
GABA
Interacts with419 drugs
GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...
GABA monograph & interactionsGaba- S by Nutri-West Drug Interactions
HelloPharmacist Interaction Report
Nutri-West Gaba-S contains GABA, which interacts with blood pressure medications and central nervous system depressants.
The most serious concern is with antihypertensive drugs (blood pressure medications) — GABA may add to their effect and lower your blood pressure further than intended.
Read the full breakdown — every affected drug type, severity by severity
GABA may also have additive sedative effects when combined with central nervous system depressants like sleep aids, sedatives, or prescription pain relievers, though it's unclear how clinically relevant this is in practice.
Alternately, we could not check inactive ingredients for interactions because none are listed. If you take blood pressure medication, sedatives, or sleep aids, run your exact medications through the interaction checker on this page before starting.
Altogether, these interactions span 419 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Gaba- S?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gaba- S interact with 419 drugs. Click any drug to see the details.
1 of the 1 ingredient in Gaba- S interact with drugs. Each result below shows which ingredient is responsible. GABA
AcebutololRhotral, Sectral
How Acebutolol interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaCns Depressants, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants.
Read the full Gaba + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Gaba- S — through 1 ingredient. Tap an ingredient for the detail:
GabaAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gaba + Bumetanide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gaba- S with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
GABA
Antihypertensive Drugs
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.
Cns Depressants
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.
Brand information
Manufacturer and brand details for Gaba- S, from the product label.
Gaba- S by Nutri-West: Common Questions
Does Gaba- S by Nutri-West interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is GABA and what does it do in my body?
Will GABA help with my anxiety?
What side effects might I experience?
Is GABA safe to take long-term?
Can I take GABA if I'm pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gaba- S is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gaba- S’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Gaba- S's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Gamma-aminobutyric Acid (gaba) 12 references
- Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
- Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
- Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
- Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
- Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
- ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
- Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
- Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
- Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
- Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
- Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
- de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed
See these in context on the Gamma-aminobutyric Acid (gaba) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC