Hawthorne Berry Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hawthorne Berry Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hawthorne Berry Extract is a dietary supplement by Dr. Wong's Essentials with 2 active ingredients. Its ingredients are commonly taken for heart failure symptoms, high blood pressure, chest pain (angina).Based on those ingredients, 191 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Hawthorne berry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hawthorne Berry Extract by Dr. Wong's Essentials
Ask about any prescription or over-the-counter medication and we check it for interactions with Hawthorne Berry Extract by Dr. Wong's Essentials — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hawthorne Berry Extract by Dr. Wong's Essentials
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 2 active ingredients: a proprietary blend (whose breakdown isn't disclosed on the label) and serratiopeptidase, an enzyme. The hawthorn berry extract—the main component listed separately—is the ingredient with documented effects on the heart and blood vessels.
The capsule itself is made from gelatin and vegetable cellulose, with magnesium stearate and silicon dioxide as processing agents.
Does it work?
Couldn't assess
The evidence we hold for hawthorn berry extract rates as insufficient for angina, anxiety, arrhythmia, atherosclerosis, cardiovascular disease, and cognitive function. That means the studies we reviewed don't yet establish whether it works for these uses.
If you're thinking about this product for a specific condition, talk with your doctor or pharmacist about what the research actually shows and whether it's right for you.
How safe is it?
Well-documented data
Hawthorn is generally well tolerated when used appropriately, though if you have a heart condition, medical supervision is important. Rare serious adverse effects include multiorgan hypersensitivity reactions with kidney damage.
More common side effects reported in studies include bronchitis, slow breathing, and palpitations (a fluttering feeling in the chest); palpitations appeared in a small number of patients across large trials of people with heart failure. The safety information we hold advises against use during pregnancy and while breastfeeding because there isn't enough data to know either way.
Talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Major interaction found
Before taking this product, double-check with your doctor or pharmacist if you take nitrates or phosphodiesterase-5 inhibitors (Major severity), or beta-blockers, calcium channel blockers, digoxin, or blood thinners like warfarin or aspirin (Moderate severity). Altogether, these interactions span 191 individual medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
This product is designed for people interested in heart and cardiovascular support, but it's not for everyone—especially if you take blood pressure medications, heart-rhythm drugs, blood thinners, or erectile-dysfunction medications. The evidence for its effectiveness isn't established in our data.
Because hawthorn affects blood vessels and heart rate, you'll want to check with your own doctor or pharmacist before starting it alongside any cardiac medication.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hawthorne Berry Extract, straight from the product label.
| Brand | Dr. Wong's Essentials |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 204186 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hawthorne Berry Extract by Dr. Wong's Essentials, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1470 mg | -- |
| Serratiopeptidase | 0 NP | -- |
| Hawthorne berry extract | 0 NP | -- |
Other ingredients: Gelatin, Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, 1-2 capsules once or twice daily as needed or as directed by your health care provider.
Precautions
Keep out of the reach of children.
Tamper resistant package. Do not use if outer seal is missing.
Formulation
This product contains no gluten, milk, eggs, wheat, soybeans, peanuts, tree nuts, fish or shellfish.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
WAM Essentials, Inc. Fanning the winds of change
FDA Statement of Identity
Herbal Supplement with Serrapeptidase
Formula
Herbal Supplement with Serrapeptidase
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hawthorne Berry Extract by Dr. Wong's Essentials label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hawthorne Berry Extract by Dr. Wong's Essentials
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Serratiopeptidase
- › Hawthorne berry extract
Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Hawthorne Berry Extract by Dr. Wong's Essentials Drug Interactions
HelloPharmacist Interaction Report
Dr.
Wong's Essentials Hawthorne Berry Extract interacts with medications through its hawthorn berry extract content, with the most serious interactions being Major-severity effects on nitrates and phosphodiesterase-5 inhibitors (drugs like sildenafil used for erectile dysfunction). With nitrates, hawthorn may add to their blood-vessel-relaxing effects in ways we don't fully understand.
With phosphodiesterase-5 inhibitors, the concern is similar: additive vasodilation and a potential drop in blood pressure.
Read the full breakdown — every affected drug type, severity by severity
Hawthorn also carries Moderate-severity interactions with blood pressure and heart-rate medications, including beta-blockers, calcium channel blockers, and heart-rhythm drugs like digoxin. It may lower blood pressure and slow heart rate on its own, which could amplify the effects of these medications.
Additionally, there's a Moderate-severity flag for blood thinners (anticoagulants and antiplatelet drugs): lab and animal research suggests hawthorn may inhibit blood clotting, though the effect in people isn't clear, and one observational study linked hawthorn use just before heart surgery to potential bleeding concerns.
We could not check serratiopeptidase, an enzyme ingredient in this product, because we hold no interaction data for it.
Additionally, use the medication checker on this page to verify your specific drugs — and talk with your doctor or pharmacist before combining this product with any heart or blood-pressure medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hawthorne Berry Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hawthorne Berry Extract interact with 191 drugs. Click any drug to see the details.
1 of the 2 ingredients in Hawthorne Berry Extract interact with drugs. Each result below shows which ingredient is responsible. Hawthorne berry extract
AvanafilStendra
How Avanafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Avanafil interactionFinasteride, TadalafilEntadfi
How Finasteride, Tadalafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Finasteride, Tadalafil interactionGlyceryl TrinitrateNitronal
How Glyceryl Trinitrate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Glyceryl Trinitrate interactionIsosorbide DinitrateAngitak, Cedocard Retard, Isoket, Isoket Retard, Isordil
How Isosorbide Dinitrate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Isosorbide Dinitrate interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Isosorbide Dinitrate, Hydralazine interactionIsosorbide MononitrateAngeze, Angeze SR, Chemydur 60XL, Dynamin, Elantan, Elantan LA +13 more
How Isosorbide Mononitrate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Isosorbide Mononitrate interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Macitentan, Tadalafil interactionNicorandilAprior, Dancor, Ikorel, Sigmart, Zynicor
How Nicorandil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Nicorandil interactionNitroglycerinGonitro, Nitro Time, Nitro-Bid, Nitrocine Timecaps, Nitrogard, Nitrogard SR +7 more
How Nitroglycerin interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Nitroglycerin interactionPentaerythritol TetranitratePeritrate, Peritrate SA
How Pentaerythritol Tetranitrate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractNitrates Major
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Read the full Hawthorne Berry Extract + Pentaerythritol Tetranitrate interactionSildenafilRevatio
How Sildenafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Sildenafil interactionSildenafil CitrateViagra
How Sildenafil Citrate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Sildenafil Citrate interactionTadalafilCialis, Tadliq
How Tadalafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Tadalafil interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractPhosphodiesterase-5 Inhibitors Major
Interaction Summary
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Read the full Hawthorne Berry Extract + Vardenafil interactionAbciximabReoPro
How Abciximab interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractBeta-blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Read the full Hawthorne Berry Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Hawthorne Berry Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmlodipineNorliqva
How Amlodipine interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorne Berry Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorne Berry Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorne Berry Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorne Berry Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Hawthorne Berry Extract — through 1 ingredient. Tap an ingredient for the detail:
Hawthorne Berry ExtractCalcium Channel Blockers Moderate
Interaction Summary
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Read the full Hawthorne Berry Extract + Amlodipine Besylate, Benazepril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hawthorne Berry Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hawthorne berry extract
Nitrates
Theoretically, concomitant use might cause additive coronary vasodilatory effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Phosphodiesterase-5 Inhibitors
Theoretically, concomitant use might result in additive vasodilation and hypotension.
Hawthorn might inhibit PDE-5 and cause vasodilation.
Anticoagulant/Antiplatelet Drugs
Theoretically, hawthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research shows that hawthorn can inhibit platelet aggregation. However, its effect in humans is unclear. One observational study shows that patients taking hawthorn shortly before undergoing coronary artery bypass graft (CABG) surgery or valve replacement surgery have a 10% incidence of postoperative bleeding, compared with 1% in those who never consumed hawthorn extract. However, clinical research shows that taking a specific preparation of dried hawthorn leaves and flowers (Crataesor, Soria Natural Lab) 800 mg three times daily for 15 days does not affect platelet aggregation or levels of thromboxane B2, the metabolite of thromboxane A2, in healthy humans.
Beta-Blockers
Theoretically, concomitant use might cause additive effects on blood pressure and heart rate.
Some evidence shows that hawthorn might lower blood pressure and heart rate.
Calcium Channel Blockers
Theoretically, concomitant use might cause additive coronary vasodilation and hypotensive effects.
Some evidence shows that hawthorn might lower blood pressure due to vasodilatory effects.
Digoxin (Lanoxin)
Theoretically, hawthorn might potentiate the effects and adverse effects of digoxin.
Hawthorn appears to improve cardiac output; however, hawthorn does not appear to affect digoxin pharmacokinetics. Case reports suggest that at least one species of hawthorn root extract (Crataegus mexicana) may produce adverse effects similar to digoxin and can cross-react with digoxin assays, leading to falsely elevated plasma digoxin levels.
Brand information
Manufacturer and brand details for Hawthorne Berry Extract, from the product label.
Dr. Wong's Essentials
See all Dr. Wong's Essentials products- Name
- WAM Essentials, Inc.
- Street Address
- 320 Grant Ave.
- City
- Strawn
- State
- TX
- ZipCode
- 76475
- Phone Number
- 1-866-268-3216
Hawthorne Berry Extract by Dr. Wong's Essentials: Common Questions
Does Hawthorne Berry Extract by Dr. Wong's Essentials interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is serratiopeptidase, and why is it in this product?
Is it safe to take this if I have a heart condition?
Can I take this while pregnant or breastfeeding?
Does hawthorn actually work for the heart?
What side effects should I watch for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hawthorne Berry Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hawthorne Berry Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hawthorne Berry Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hawthorn 25 references
- Tauchert M. Efficacy and safety of crataegus extract WS 1442 in comparison with placebo in patients with chronic stable New York Heart Association class-III heart failure. Am Heart J 2002;143:910-5. PubMed
- Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003;114:665-74.. PubMed
- Chang Q, Zuo Z, Harrison F, Chow MS. Hawthorn. J Clin Pharmacol 2002;42:605-12.
- Holubarsch CJ, Colucci WS, Meinertz T, et al. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail 2008;10:1255-63. PubMed
- Pittler MH, Guo R, and Ernst E. Hawthorn extract for treating chronic heart failure. Cochrane.Database.Syst Rev 2008:CD005312. PubMed
- Zick SM, Vautaw BM, Gillespie B, Aaronson KD. Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial. Eur J Heart Fail. 2009;11:990-99. PubMed
- Werner NS, Duschek S, and Schandry R. D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. Phytomedicine. 2009;16:1077-82. PubMed
- Dalli E, Colomer E, Tormos MC, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 6-15-2011;18:769-75. PubMed
- Maek-a-nantawat W, Phonrat B, Dhitavat J, et al. Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients. Southeast Asian J Trop.Med Public Health 2009;40:494-501.
- Asher GN, Viera AJ, Weaver MA, et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC.Complement Altern.Med 2012;12:26. PubMed
- Walker AF, Marakis G, Simpson E, et al. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen.Pract 2006;56:437-43.
- Daniele C, Mazzanti G, Pittler MH, et al. Adverse-event profile of Crataegus spp.: a systematic review. Drug Saf 2006;29:523-35. PubMed
- Tankanow R, Tamer HR, Streetman DS, et al. Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha). J.Clin.Pharmacol. 2003;43:637-42. DOI
- Tauchert, M., Gildor, A., and Lipinski, J. [High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure]. Herz 1999;24(6):465-474.
- Horoz, M., Gok, E., Genctoy, G., Ozcan, T., Olmaz, R., Akca, M., Kiykim, A., and Gurses, I. Crataegus orientalis associated multiorgan hypersensitivity reaction and acute renal failure. Intern.Med 2008;47(23):2039-2042. PubMed
- Dalli, E., Valles, J., Cosin-Sales, J., Santos, M. T., Moscardo, A., Milara, J., and Sotillo, J. F. Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. Thromb.Res 2011;128(4):398-400. PubMed
- Rogov VD. [Toxiderma due to the fruits of the hawthorn]. Vestn Dermatol Venerol 1984;7(7):46-47.
- Loew D, Albrecht M, and Podzuweit H. Efficacy and tolerability of a Hawthorn preparation in patients with heart failure Stage I and II according to NYHA - a surveillance study. Phytomedicine 1996;3(Suppl 1):92.
- Rababa'h AM, Altarabsheh SE, Haddad O, Deo SV, Obeidat Y, Al-Azzam S. Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach. Heart Surg Forum 2016;19(4):E175-9. PubMed
- Shatoor AS, Soliman H, Al-Hashem F, Gamal BE, Othman A, El-Menshaw N. Effect of hawthorn (Crataegus aronia syn. Azarolus (L)) on platelet function in albino wistar rats. Thromb Res 2012;130(1):75-80. PubMed
- Vibes J, Lasserre B, Gleye J, Declume C. Inhibition of thromboxane A2 biosynthesis in vitro by the main components of Crataegus oxyacantha (hawthorn) flower heads. Prostaglandins Leukot Essent Fatty Acids 1994;50(4):173-5. PubMed
- Rogers KL, Grice ID, Griffiths LR. Inhibition of platelet aggregation and 5-HT release by extracts of Australian plants used traditionally as headache treatments. Eur J Pharm Sci 2000;9(4):355-63. PubMed
- Zhou CC, Huang XX, Gao PY, et al. Two new compounds from Crataegus pinnatifida and their antithrombotic activities. J Asian Nat Prod Res 2014;16(2):169-74.
- Palmer KG, Lebin JA, Cronin MT, Mazor SS, Burns RA. Crataegus mexicana (Tejocote) Exposure Associated with Cardiotoxicity and a Falsely Elevated Digoxin Level. J Med Toxicol. 2019;15(4):295-298. PubMed
- Espinosa J, Bassett R, Lucerna A, Finn D. Hawthorne root (Crataegus mexicana) toxicity. Am J Emerg Med. 2024;78:242.e5-242.e6. PubMed
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