Hempanol-CF Ingredients & Drug Interactions
by North American Herb & Spice
What is this page for?
First and foremost: checking Hempanol-CF against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hempanol-CF is a dietary supplement by North American Herb & Spice with 2 active ingredients. Its ingredients are commonly taken for memory and concentration, digestive upset, hair growth.Based on those ingredients, 1,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract, wild Rosemary Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hempanol-CF by North American Herb & Spice
Ask about any prescription or over-the-counter medication and we check it for interactions with Hempanol-CF by North American Herb & Spice — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hempanol-CF by North American Herb & Spice
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Hempanol-CF contains two active ingredients: wild rosemary oil and a proprietary blend that includes raw, CO2 extract from high beta-caryophyllene and phytoterpene hemp stalk extract. The product has no inactive ingredients listed.
Does it work?
Moderate evidence
The rosemary oil in this product is possibly effective for memory, according to the evidence we hold. For other uses—age-related cognitive decline, hair loss (alopecia areata), and fatty liver disease—the evidence is insufficient to rate whether it works.
The hemp extract's effectiveness for constipation, eczema, or cholesterol problems is also insufficient to rate in our data.
How safe is it?
Well-documented data
Rosemary oil is safe in normal food amounts, but concentrated extracts and undiluted essential oil need caution. The product may cause allergic reactions when applied to skin, swelling of the lips and gums when used in the mouth, and rarely, occupational asthma if inhaled.
Undiluted rosemary oil might trigger seizures. Hemp products are generally well tolerated in food amounts, but concentrated extracts are less studied.
Rare cases of allergic reactions—including hives, facial swelling, and anaphylaxis—have been reported, and one case of liver inflammation occurred in a young child given high doses of hemp extract. For pregnancy, rosemary is rated possibly unsafe; food amounts are likely fine, but medicinal doses should be avoided.
There is not enough safety data on medicinal-dose hemp during lactation to know either way.
Meds to double-check
Moderate interaction found
Check before combining this product with blood thinners or antiplatelet drugs (moderate-severity risk of bleeding), diabetes medications (moderate-severity risk of low blood sugar), aspirin and salicylate-containing pain relievers (moderate-severity additive effects), hormone therapy (moderate-severity), blood pressure medications and ACE inhibitors (minor-severity), and any drugs your liver metabolizes quickly, especially through the CYP1A2 and CYP3A4 pathways (minor-severity). Your pharmacist can confirm whether your specific medications are affected.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be worth considering if you're interested in memory support and tolerate herbal supplements well. However, if you take blood thinners, diabetes medications, aspirin-type drugs, or blood pressure medications, talk with your doctor or pharmacist before starting—the interactions are real and may affect how your drugs work.
If you have a history of allergies to herbs or hemp, proceed cautiously and discuss it with your healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hempanol-CF, straight from the product label.
| Brand | North American Herb & Spice |
|---|---|
| Barcode (UPC) | 635824006619 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 241976 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hempanol-CF by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| wild Rosemary Oil | 0 NP | -- |
| Proprietary Blend | 460 mg | -- |
| raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take 20 drops under the tongue or in juice/water once daily.
Formula
Hempanol-CF, powered by CO2-extracted cannabis extract, supports a healthy nervous system by activating the body’s CB2 receptor system. Stay calm and focused with this potent formula. Naturally rich in cannabinoids and phytoterpenes, Hempanol-CF is the ideal hemp-cannabis extract for daily use.
Whole food hemp 1500 mg hemp extract per bottle
18% hemp phytoterpenes
Formulation
Unlike other cannabis products, it’s free of all solvents and is never heat-treated. That's why it is the most potent of all.
Calm, focus, & nerve support
Non GMO
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hempanol-CF by North American Herb & Spice label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hempanol-CF by North American Herb & Spice
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size20 Drop(s) Dosage formLiquid Servings per container43 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Hempanol-CF by North American Herb & Spice Drug Interactions
HelloPharmacist Interaction Report
Hempanol-CF from North American Herb & Spice has documented interactions through its wild rosemary oil and hemp extract.
The most serious concern is moderate-severity risk: rosemary may increase bleeding risk if you're taking blood thinners (anticoagulants) or antiplatelet drugs. Rosemary works by slowing how your blood cells clump together, which adds to the effect of these medications.
Read the full breakdown — every affected drug type, severity by severity
Rosemary also carries moderate-severity interactions with diabetes medications—it may lower your blood sugar further and raise the risk of low blood sugar (hypoglycemia)—and with aspirin and similar salicylate-containing pain relievers (choline magnesium trisalicylate, salsalate), where it may have additive effects. There's also a minor interaction with certain drugs your liver breaks down quickly (CYP1A2 substrates); rosemary may speed up how your body clears them, making them less effective.
Hemp extract adds minor-severity interactions with hormone therapies (estrogens), blood pressure medications (antihypertensives and ACE inhibitors), blood thinners, and drugs metabolized by your liver (CYP1A2 and CYP3A4 substrates). The hemp component may theoretically lower blood pressure further or increase bleeding risk, though human evidence is limited.
Altogether, these interactions span 1,023 individual medications. Use the medication checker on this page to look up your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hempanol-CF?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hempanol-CF interact with 1,022 drugs. Click any drug to see the details.
2 of the 2 ingredients in Hempanol-CF interact with drugs. Each result below shows which ingredient is responsible. raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract wild Rosemary Oil
AbciximabReoPro
How Abciximab interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Abciximab interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Abrocitinib interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Hempanol-CF — through 1 ingredient. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Acenocoumarol interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wild Rosemary Oil + Acetaminophen, Aspirin interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wild Rosemary Oil + Acetaminophen, Aspirin, Caffeine interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wild Rosemary Oil + Acetaminophen, Ibuprofen interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Hempanol-CF — through 1 ingredient. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Acetylsalicylic Acid interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Hempanol-CF — through 1 ingredient. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Alogliptin interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Hempanol-CF — through 1 ingredient. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Alogliptin, Pioglitazone interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Alteplase, Tpa interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Anacaulase-bcdb interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wild Rosemary Oil + Anagrelide interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Anisindione interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Hempanol-CF — through 1 ingredient. Tap an ingredient for the detail:
Wild Rosemary OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Wild Rosemary Oil + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Antithrombin Iii interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Apixaban interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Argatroban interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Aspirin interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAnticoagulant/antiplatelet Drugs, Aspirin Moderate
Interaction Summary
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Wild Rosemary Oil + Aspirin, Butalbital interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Aspirin, Butalbital, Caffeine interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Wild Rosemary Oil + Aspirin, Butalbital, Caffeine, Phenacetin interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Hempanol-CF — through 2 ingredients. Tap an ingredient for the detail:
Wild Rosemary OilAspirin, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Read the full Wild Rosemary Oil + Aspirin, Caffeine interactionRaw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Raw, Co2 Extract From High Beta Caryophyllene & Phytoterpene Hemp Stalk Extract + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hempanol-CF with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
raw, CO2 extract from high beta Caryophyllene & phytoterpene hemp stalk extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
wild Rosemary Oil
Anticoagulant/Antiplatelet Drugs
Theoretically, rosemary may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that rosemary inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, taking rosemary with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that rosemary extract can decrease blood glucose levels in diabetic models. However, research in humans is conflicting. Although rosemary powder decreased blood glucose levels in healthy adults, no change in blood glucose levels was seen in adults with type 2 diabetes, most of whom were taking antidiabetes drugs.
Aspirin
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as aspirin.
Rosemary is reported to contain salicylates.
Choline Magnesium Trisalicylate (Trilisate)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as choline magnesium trisalicylate.
Rosemary is reported to contain salicylate.
Salsalate (Disalcid)
Theoretically, rosemary might have additive effects with salicylate-containing drugs such as salsalate.
Rosemary is reported to contain salicylate.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, rosemary might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that rosemary induces CYP1A2 enzymes. This effect has not been reported in humans.
Brand information
Manufacturer and brand details for Hempanol-CF, from the product label.
North American Herb & Spice
See all North American Herb & Spice products- Name
- NAHS
- Street Address
- 13900 W Polo Trail Drive
- City
- Lake Forest
- State
- IL
- ZipCode
- 60045
- Phone Number
- 1-800-243-5242
- Web Address
- www.oreganol.com
Hempanol-CF by North American Herb & Spice: Common Questions
Does Hempanol-CF by North American Herb & Spice interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does the rosemary oil in this product actually do?
Is this safe if I have a history of allergies?
Can I take this while pregnant?
Can rosemary oil cause seizures?
What's the difference between food amounts and the amounts in this supplement?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hempanol-CF’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Rosemary
Interacts with 372 drugsRosemary is a fragrant Mediterranean herb that is safe and flavorful in normal food amounts. Some early research suggests possible benefits for memory, mood, and hair growth, but the evidenc...
Read the full Rosemary monograph → Herb & supplement monographHemp
Interacts with 938 drugsHemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for most people as part of the diet. While...
Read the full Hemp monograph →Sources & How We Checked
Hempanol-CF's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 32 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rosemary 20 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Cartier LC, Lehrer A, Malo JL. Occupational asthma caused by aromatic herbs. Allergy 1996;51:647-9. DOI
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Swain AR, Dutton SP, Truswell AS. Salicylates in foods. J Am Diet.Assoc 1985;85(8):950-60. DOI
- Zhu BT, Loder DP, Cai MX, et al. Dietary administration of an extract from rosemary leaves enhances the liver microsomal metabolism of endogenous estrogens and decreases their uterotropic action in CD-1 mice. Carcinogenesis 1998;19(10):1821-7. PubMed
- Debersac P, Heydel JM, Amiot MJ, et al. Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns. Food Chem Toxicol 2001;39(9):907-18. PubMed
- Debersac P, Vernevaut MF, Amiot MJ, et al. Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver. Food Chem Toxicol 2001;39(2):109-17. PubMed
- Lee JJ, Jin YR, Lee JH, et al. Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis. Planta Med 2007;73(2):121-7.
- Yamamoto J, Yamada K, Naemura A, et al. Testing various herbs for antithrombotic effect. Nutrition 2005;21(5):580-7. PubMed
- Naemura A, Ura M, Yamashita T, et al. Long-term intake of rosemary and common thyme herbs inhibits experimental thrombosis without prolongation of bleeding time. Thromb Res 2008;122(4):517-22. PubMed
- Lee JJ, Jin YR, Lim Y, et al. Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. Vascul Pharmacol 2006;45:148-53. PubMed
- Bakirel, T., Bakirel, U., Keles, O. U., Ulgen, S. G., and Yardibi, H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J Ethnopharmacol 2-28-2008;116(1):64-73. PubMed
- Erenmemisoglu, A., Saraymen, R., and Ustun, S. Effect of a Rosmarinus officinalis leave extract on plasma glucose levels in normoglycaemic and diabetic mice. Pharmazie 1997;52(8):645-646.
- Valones MAA, Silva ICG, Gueiros LAM, Leão JC, Caldas AF Jr, Carvalho AAT. Clinical assessment of rosemary-based toothpaste (Rosmarinus officinalis Linn.): A randomized controlled double-blind study. Braz Dent J. 2019;30(2):146-151. PubMed
- Quirarte-Báez SM, Zamora-Perez AL, Reyes-Estrada CA, et al. A shortened treatment with rosemary tea (rosmarinus officinalis) instead of glucose in patients with diabetes mellitus type 2 (TSD). J Popul Ther Clin Pharmacol. 2019;26(4):e18-e28.
- Al Jamal A. Effect of rosemary (Rosmarinus officinalis) on lipid profiles and blood glucose in human diabetic patients (type-2). African J. Biochem. Res. 2014;8(8):147-50. DOI
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC