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Dietary supplement

Raw Hempanol Super Strength 140 mg Ingredients & Drug Interactions

by North American Herb & Spice

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Raw Hempanol Super Strength 140 mg is a dietary supplement by North American Herb & Spice with 2 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are raw, CO2 extract from high beta Caryophyllene Hemp stalk, raw, organic, CO2-extracted Oregano. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Raw Hempanol Super Strength 140 mg by North American Herb & Spice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (280 mg) without saying how much of each component you get.

Raw Hempanol Super Strength contains 2 active ingredients: raw, organic, CO2-extracted oregano and raw, CO2-extracted hemp stalk high in beta-caryophyllene (a natural compound in hemp). The softgel capsule also contains beef gelatin as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: healthy neurological system and inflammation support.
  • We looked for evidence on: Multiple sclerosis (MS), neuroprotection, neuroinflammation.
  • The closest evidence on file: Hemp is rated "Insufficient Reliable Evidence To Rate" for Multiple sclerosis (MS) (Natural Medicines).

The product is marketed for various uses, but the evidence we hold on file does not establish effectiveness. For oregano, the data rates effectiveness as insufficient for acne, bronchitis, asthma, headache, and upper respiratory tract infection.

For hemp stalk extract, effectiveness is rated insufficient for constipation, eczema, and familial hypercholesterolemia. No established evidence supports this product's intended use.

The evidence, ingredient by ingredient Oregano Hemp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated in food amounts, but concentrated supplements like this one are less studied. The most common side effect is gastrointestinal upset.

Rarely, oregano can cause serious allergic reactions including anaphylaxis, especially in people sensitive to plants in the mint family (Lamiaceae). Hemp products are generally well tolerated in food amounts; in larger amounts, hemp seed oil seems well tolerated.

Rare serious effects include anaphylaxis, heart rhythm problems (long QT syndrome, torsades de pointes), and in one case report, liver inflammation in a young child given high-dose hemp extract. Food allergies to hemp seed are uncommon but can trigger anaphylaxis and airway swelling.

Because this is a concentrated supplement extract — not a food amount — safety is less well established than for everyday oregano and hemp seed foods.

Side effects, ingredient by ingredient Oregano Hemp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Oregano, Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,019 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Raw Hempanol, double-check with your doctor or pharmacist if you take blood thinners (anticoagulant or antiplatelet drugs) — oregano may increase bleeding risk. Also check if you're on diabetes drugs (oregano may lower blood sugar), blood pressure or ACE inhibitor medications (hemp may lower pressure additively), hormone therapy (hemp may interfere), or drugs metabolized by liver enzymes (CYP1A2 or CYP3A4 substrates — hemp may reduce their effectiveness).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product pairs oregano and hemp in concentrated form. If you take blood thinners, diabetes medication, blood pressure drugs, ACE inhibitors, hormone therapy, or drugs metabolized by liver enzymes, talk with your doctor or pharmacist before starting it.

Even if you don't take medications, mention any history of allergies to mint-family plants or hemp seed, since this supplement is much stronger than food amounts. Your doctor or pharmacist can review your full medication list and help you decide whether this product is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raw Hempanol Super Strength 140 mg, straight from the product label.

Brand North American Herb & Spice
Barcode (UPC) 635824006527
Net contents 50 Softgel(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241975
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raw Hempanol Super Strength 140 mg by North American Herb & Spice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
25
UPC/BARCODE
635824006527
IngredientAmount% DV
Proprietary Blend280 mg--
raw, organic, CO2-extracted Oregano0 NP--
raw, CO2 extract from high beta Caryophyllene Hemp stalk0 NP--

Other ingredients: BSE-free Beef Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules daily.

Formula

Through the powers of CO2-extracted, raw hemp and wild, raw oregano, Hempanol supports healthy neurological system. A natural source of beta caryophyllene and other phytoterpenes, it is the only full-spectrum hemp plus wild oregano complex available. The hemp extract in Hempanol is 100% raw.

Whole food hemp 1800 mg hemp extract per bottle

35% Phytoterpenes (raw hemp + oregano)

Formulation

No solvents are used.

Healthy inflammation support

General Statements

Enduring wellness is the key for a great life.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Raw Hempanol Super Strength 140 mg by North American Herb & Spice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Raw Hempanol Super Strength 140 mg by North American Herb & Spice

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

280 mg per serving Form: organic extra virgin Olive Oil

Other (inactive) ingredients: BSE-free Beef Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raw Hempanol Super Strength 140 mg by North American Herb & Spice Drug Interactions

Want to check YOUR meds against Raw Hempanol Super Strength 140 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,018Drugs
249 Moderate 769 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Raw Hempanol Super Strength 140 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

raw, CO2 extract from high beta Caryophyllene Hemp stalk6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D

raw, organic, CO2-extracted Oregano2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Raw Hempanol Super Strength 140 mg, from the product label.

North American Herb & Spice

See all North American Herb & Spice products
Name
North American Herb & Spice
Street Address
13900 Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-800-243-5242
Web Address
www.oreganol.com
Pharmacist Counseling Corner

Raw Hempanol Super Strength 140 mg by North American Herb & Spice: Common Questions

Does Raw Hempanol Super Strength 140 mg by North American Herb & Spice interact with any medications?
Yes. Based on its ingredients, Raw Hempanol Super Strength 140 mg has a known interaction with 1,018 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raw Hempanol Super Strength 140 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Oregano at medicinal or supplement doses is rated possibly unsafe in pregnancy — food amounts are likely fine, but this concentrated supplement should be avoided. The data on hemp during pregnancy isn't rated in our file. Talk with your doctor or pharmacist for personalized advice before taking this product if you're pregnant.
Is it safe while breastfeeding?
Food amounts of oregano and hemp seed are likely okay, but the safety of concentrated supplements while breastfeeding is not established for either ingredient. Check with your doctor or pharmacist before using this product if you're nursing.
What does this product actually do?
The product contains oregano and hemp stalk extract, but the evidence we hold doesn't establish that either works reliably for any particular condition. If you're interested in it for a specific health goal, ask your doctor or pharmacist whether the research supports it.
Could this cause an allergic reaction?
Yes — though rare, both oregano and hemp seed can trigger serious allergic reactions including anaphylaxis, especially in people sensitive to mint-family plants or with hemp seed allergies. If you've had allergies to oregano, thyme, or hemp, don't take this without talking to your doctor first.
What's the most common side effect?
Oregano commonly causes gastrointestinal upset in larger doses. Hemp products are generally well tolerated, though rare serious heart rhythm problems have been reported. Most people taking normal food amounts of these ingredients don't experience problems.
Does this product have fillers?
The only inactive ingredient listed is beef gelatin, which is the capsule material. There are no other fillers noted.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raw Hempanol Super Strength 140 mg label
Sources

Sources & How We Checked

Raw Hempanol Super Strength 140 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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