Major interaction on record — check this product against your medications before combining. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Inner Grounding Detox Ingredients & Drug Interactions

by Ormus Minerals

Capsule Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Inner Grounding Detox is a dietary supplement by Ormus Minerals with 6 active ingredients. Its ingredients are commonly taken for digestive cleansing or 'detox', intestinal parasite support, skin, hair, and nail health (silica).Based on those ingredients, 2,119 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are activated Coconut Fiber Carbon, pure Fulvic Acid powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Inner Grounding Detox by Ormus Minerals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Ingredients” is listed as a grouped ingredient — the label gives one combined amount (465 mg) without saying how much of each component you get.

This capsule contains six ingredients. The active components are bentonite clay, diatomaceous earth, activated coconut fiber carbon (a form of activated charcoal), micronized zeolite, humic and fulvic powder, and pure fulvic acid powder.

These are meant to work as a detoxification blend. The capsule itself is made from gelatin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

  • Poisoning via Activated Charcoal Possibly Effective
Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Poisoning — rated "Possibly Effective" (Activated Charcoal) (Natural Medicines).

The evidence for what this product actually does is thin. Activated charcoal is possibly effective for poisoning, but the product's other ingredients — diatomaceous earth, zeolite, humic compounds, and fulvic acid — have insufficient reliable evidence to show they work for the conditions they're marketed for, according to the data we hold.

There's not enough research to rate their usefulness.

The evidence, ingredient by ingredient Diatomaceous Earth Activated Charcoal Fulvic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Activated charcoal is generally well tolerated in the short term, though it commonly causes constipation, black stools, bloating, and abdominal pain. Diatomaceous earth has very limited safety data in humans; the facts note you should use only food-grade products if you ingest it, and there's concern about crystalline silica content linked to lung issues in industrial settings.

Fulvic acid appears tolerated orally, with the most common side effects being diarrhea, headache, and sore throat. Pregnancy and breastfeeding safety is a concern: diatomaceous earth is best avoided in both, and fulvic acid lacks enough data — avoid it in pregnancy and breastfeeding.

Activated charcoal is possibly safe in pregnancy, but use only under medical guidance. High-quality human safety data for most of these ingredients is limited.

Side effects, ingredient by ingredient Diatomaceous Earth Activated Charcoal Fulvic Acid

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Activated Charcoal, Fulvic Acid.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 2,120 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Inner Grounding Detox, check with your doctor or pharmacist if you take any oral medications, blood thinners or antiplatelet drugs, birth control pills, immunosuppressants, or thyroid hormone therapy. Activated charcoal can reduce how your body absorbs many drugs, and fulvic acid may interfere with blood clotting and thyroid function.

Alcohol may also reduce how well the charcoal in this product works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

This is a multi-ingredient detox blend with documented interactions — especially with oral medications, birth control, blood thinners, immunosuppressants, and thyroid drugs. If you take any prescription medication, immunosuppressant, or thyroid hormone, you need to check your specific drugs before using this.

Talk with your doctor or pharmacist about whether this product fits your health picture, and be aware that safety data is sparse and effectiveness is not well established.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inner Grounding Detox, straight from the product label.

Brand Ormus Minerals
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Feb 26, 2020
DSLD ID 213274
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inner Grounding Detox by Ormus Minerals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
IngredientAmount% DV
Bentonite Clay0 NP--
Ingredients465 mg--
Diatomaceous Earth0 NP--
activated Coconut Fiber Carbon0 NP--
micronized Zeolite0 NP--
Humic/Fulvic powder0 NP--
pure Fulvic Acid powder0 NP--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 2-4 capsules daily.

Precautions

Precautions: Keep away from children.

Consult with health provider for use of this product.

Formulation

465 mg 100% natural

No preservatives

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Inner Grounding Detox by Ormus Minerals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Inner Grounding Detox by Ormus Minerals

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Ingredients

465 mg per serving

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inner Grounding Detox by Ormus Minerals Drug Interactions

Want to check YOUR meds against Inner Grounding Detox?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,119Drugs
2,022 Major 97 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Inner Grounding Detox with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

activated Coconut Fiber Carbon3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B

pure Fulvic Acid powder3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Inner Grounding Detox, from the product label.

Ormus Minerals

See all Ormus Minerals products
Name
Ormus Minerals Inc.
Street Address
Post Office Box 513
City
Caldwell
State
Idaho
ZipCode
83606
Web Address
www.OrmusMinerals.com
Pharmacist Counseling Corner

Inner Grounding Detox by Ormus Minerals: Common Questions

Does Inner Grounding Detox by Ormus Minerals interact with any medications?
Yes. Based on its ingredients, Inner Grounding Detox has a known interaction with 2,119 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inner Grounding Detox contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control?
Activated charcoal in this product may reduce how well oral contraceptives work, which could raise the risk of failure. Talk with your doctor or pharmacist before using this product if you rely on birth control pills.
Is it safe to use this while pregnant or breastfeeding?
No — the diatomaceous earth in this blend is best avoided in pregnancy and while breastfeeding because safety hasn't been studied. Fulvic acid also lacks enough safety data, so it should be avoided in both. Activated charcoal is possibly safe in pregnancy, but only use it under medical guidance. Talk with your doctor or pharmacist before taking this product if you're pregnant or nursing.
What are the most common side effects?
Activated charcoal often causes constipation, black stools, bloating, and abdominal pain. Fulvic acid may cause diarrhea, headache, or sore throat. Diatomaceous earth has very little human safety data, so common side effects aren't well documented.
Does this actually detox your body?
The evidence isn't strong. Activated charcoal is possibly effective for poisoning, but the other ingredients — diatomaceous earth, zeolite, and fulvic compounds — don't have enough reliable research to show they work for detoxification or the other claims made about them.
Can I take this with my thyroid medication?
The fulvic acid in this product may interfere with how well thyroid hormone therapy works. Check with your doctor or pharmacist before combining them.
What's in the capsule besides the active ingredients?
The capsule itself is made from gelatin. All the other ingredients listed are the active components of the detox blend.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inner Grounding Detox is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inner Grounding Detox label
Sources

Sources & How We Checked

Inner Grounding Detox's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Diatomaceous Earth 6 references
  1. Rushton L. Chronic obstructive pulmonary disease and occupational exposure to silica. Rev Environ Health 2007;22(4):255-72. PubMed
  2. Gallagher LG, Park RM, Checkoway H. Extended follow-up of lung cancer and non-malignant respiratory disease mortality among California diatomaceous earth workers. Occup Environ Med. 2015;72(5):360-5. PubMed
  3. Moisan S, Rucay P, Ghali A, Penneau-Fontbonne D, Lavigne C. Silica-associated limited systemic sclerosis after occupational exposure to calcined diatomaceous earth. Joint Bone Spine. 2010;77(5):472-3. PubMed
  4. Park R, Rice F, Stayner L, Smith R, Gilbert S, Checkoway H. Exposure to crystalline silica, silicosis, and lung disease other than cancer in diatomaceous earth industry workers: a quantitative risk assessment. Occup Environ Med. 2002;59(1):36-43. PubMed
  5. Nattrass C, Horwell CJ, Damby DE, Kermanizadeh A, Brown DM, Stone V. The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation. J Occup Med Toxicol. 2015 10;10:23. PubMed
  6. Wachter H, Lechleitner M, Artner-Dworzak E, Hausen A, Jarosch E, Widner B, Patsch J, Pfeiffer K, Fuchs D. Diatomaceous earth lowers blood cholesterol concentrations. Eur J Med Res. 1998 8;3(4):211-5.

See these in context on the Diatomaceous Earth monograph →

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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