Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

KetoShield Ingredients & Drug Interactions

by KS KetoSports

KetoShield label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking KetoShield against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

KetoShield is a dietary supplement by KS KetoSports with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, diabetes research, antioxidant.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phlorizin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against KetoShield by KS KetoSports

Ask about any prescription or over-the-counter medication and we check it for interactions with KetoShield by KS KetoSports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of KetoShield by KS KetoSports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

KetoShield contains one active ingredient: phlorizin, a compound that affects how your kidneys and intestines handle blood sugar by blocking two proteins involved in glucose reabsorption. The capsule also holds inactive ingredients—gelatin, microcrystalline cellulose, modified cornstarch, magnesium stearate, and silica—that serve as binders and fillers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: limit post-meal glucose spikes and manage blood sugar.
  • We looked for evidence on: Type 2 diabetes, Prediabetes, Postprandial hyperglycemia.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We have no effectiveness data on file for phlorizin as a supplement in people. Animal research showed it can lower blood glucose, but human evidence isn't in our database, so we can't tell you whether it actually works when you take it by mouth.

The evidence, ingredient by ingredient Phlorizin

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data on phlorizin supplements are very limited. Because of the lack of reliable safety information, the data advises against use in pregnancy and nursing—talk with your doctor or pharmacist about whether it's right for you if you're pregnant, planning to become pregnant, or breastfeeding.

No adverse effects are documented in our data.

Side effects, ingredient by ingredient Phlorizin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phlorizin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes medication—insulin, metformin, sulfonylureas, SGLT2 inhibitors, or other blood sugar drugs—check with your doctor or pharmacist before taking KetoShield. Phlorizin may theoretically add to their blood-sugar-lowering effect, raising the risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

KetoShield is a single-ingredient supplement aimed at blood sugar management, but human evidence for its effectiveness isn't established. The bigger question is whether it might lower your blood sugar too much if you're already on diabetes medication.

If you take any antidiabetes drug, check with your doctor or pharmacist before starting this product—they'll know your full picture and can advise on safety.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about KetoShield, straight from the product label.

Brand KS KetoSports
Barcode (UPC) 733428008050
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 249535
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for KetoShield by KS KetoSports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
733428008050
IngredientAmount% DV
Phlorizin200 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Modified Cornstarch, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

Precautions

If you are using any prescription or over the counter medicine, if you are unaware of your current medical condition, if you have any pre existing medical condition or could be pregnant or nursing, consult with physician before use.

Keep out of reach of children.

Warning: Before using this, or any new supplement, consult with your physician.

Formulation

Assists in keto transition by inhibiting sugar production and promoting glucose metabolism. Uses Limit post-meal glucose spikes Keto transitioning Manage blood sugar

Prevents glucose spikes

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule, up to three times daily, with meals, especially with meals that include carbohydrates. Do not exceed three servings per day.

Formula

Glucose Inhibitor

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in the USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

KetoShield by KS KetoSports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

KetoShield label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in KetoShield by KS KetoSports

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Phlorizin

Interacts with
86 drugs
200 mg per serving

Phlorizin is a natural plant compound (a dihydrochalcone) found in apple tree bark and other plants that has been studied mostly in the laboratory for...

Phlorizin monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Modified Cornstarch, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

KetoShield by KS KetoSports Drug Interactions

Want to check YOUR meds against KetoShield?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Phlorizin 86

Individual Drug Interactions

The ingredients in KetoShield interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in KetoShield interact with drugs. Each result below shows which ingredient is responsible. Phlorizin

Each ingredient & the kinds of drugs it affects

For each ingredient in KetoShield with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phlorizin1 drug type · 86 drugs

Antidiabetes Drugs

Phlorizin is a potent, nonselective inhibitor of SGLT1 and SGLT2. It has been shown to reduce blood glucose levels in animal research. Theoretically, phlorizin might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. However, the likelihood of this effect is unclear due to the poor bioavailability and rapid degradation of phlorizin. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Phlorizin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for KetoShield, from the product label.

KS KetoSports

See all KS KetoSports products
Name
KetoSports, Inc
Street Address
205 S. Main Street Ste B
City
Seymour
State
IL
ZipCode
61875
Web Address
www.ketosports.com
Pharmacist Counseling Corner

KetoShield by KS KetoSports: Common Questions

Does KetoShield by KS KetoSports interact with any medications?
Yes. Based on its ingredients, KetoShield has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
KetoShield contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take KetoShield if I'm pregnant or breastfeeding?
The safety data advises against use in both pregnancy and nursing because there isn't reliable information. Talk with your doctor or pharmacist before taking it in either situation—they can help you weigh the unknowns and decide what's best for you.
How much does phlorizin actually lower blood sugar?
Animal studies show it can reduce blood glucose, but we don't have human evidence for this product on file. We can't tell you what effect to expect when you take it.
What is phlorizin supposed to do?
Phlorizin blocks two proteins in your kidneys and intestines that normally reabsorb glucose. Theoretically this helps your body clear blood sugar, which is why it's in a supplement aimed at metabolic support.
What are the side effects?
No adverse effects are documented in our data for phlorizin supplements. But human safety data overall are very limited, so we can't guarantee what won't happen.
Why should I be careful if I take diabetes medication?
Phlorizin might add to the blood-sugar-lowering effect of your diabetes drug, raising the risk of low blood sugar. The effect isn't guaranteed—phlorizin doesn't absorb well—but your doctor or pharmacist should know about it before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if KetoShield is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

KetoShield label
Go deeper

The Full Monographs Behind KetoShield’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phlorizin

Interacts with 86 drugs

Phlorizin is a natural plant compound (a dihydrochalcone) found in apple tree bark and other plants that has been studied mostly in the laboratory for its effects on blood sugar handling. Th...

Read the full Phlorizin monograph →
Sources

Sources & How We Checked

KetoShield's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phlorizin 1 reference
  1. Chao EC, Henry RR. SGLT2 inhibition--a novel strategy for diabetes treatment. Nat Rev Drug Discov. 2010;9(7):551-9. PubMed

See these in context on the Phlorizin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team