Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

L-Glutamine 750 mg Ingredients & Drug Interactions

by Carlson

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Glutamine 750 mg is a dietary supplement by Carlson with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Glutamine 750 mg by Carlson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: L-glutamine, 750 mg per capsule. Glutamine is an amino acid (a building block of protein) that your body uses for energy and to support muscle and immune function.

The capsule itself is made from beef gelatin, with magnesium stearate added as a flow agent.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle tissue production and function.
  • We looked for evidence on: Exercise-induced muscle damage, Athletic performance, Muscular dystrophy, HIV/AIDS-related wasting, Critical illness (trauma), Postoperative recovery — and 3 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Muscular dystrophy.

The evidence varies by condition. Glutamine is rated Effective for sickle cell disease.

For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is Possibly Effective—meaning there's some promise but more research is needed to be sure.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Glutamine is generally well tolerated in healthy adults. The most common side effects reported with oral use are gastrointestinal: belching, bloating, constipation, diarrhea, flatulence, nausea, and vomiting.

Headache and musculoskeletal pain have also been noted. If you have kidney or liver disease, use this supplement only under medical supervision.

Pregnant women: glutamine is rated Likely Safe, but not enough data exists for breastfeeding—talk with your doctor or pharmacist before taking it while nursing.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (for seizures, nerve pain, or bipolar disorder), confirm with your doctor or pharmacist before starting this supplement. Glutamine might reduce how well these drugs work, though this hasn't been reported in actual patients yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-Glutamine may help with sickle cell disease and possibly aid recovery after surgery or during critical illness. If you take anticonvulsants, check with your doctor first—the supplement might interfere with how your medication works.

It's generally easy on the stomach in healthy people, though some experience bloating or nausea. Talk with your doctor or pharmacist about whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutamine 750 mg, straight from the product label.

Brand Carlson
Barcode (UPC) 088395068218
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241817
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutamine 750 mg by Carlson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
088395068218
IngredientAmount% DV
L-Glutamine750 mg--

Other ingredients: Beef Gelatin Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Free form amino acid

L-Glutamine promotes muscle tissue production and aids in repairing and rebuilding muscle.

FDA Statement of Identity

Dietary Supplement

Formulation

Muscle tissue production Muscle function Immune support

Gluten-free No artificial preservatives

Potency & quality guaranteed An FDA Regulated Facility

Suggested/Recommended/Usage/Directions

Directions: Adults: take one capsule one to four times daily.

Storage

Keep bottle tightly closed. Store away from heat and moisture.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

During times of extreme stress, such as intense exercise, our body depletes glutamine levels quicker than it can replenish them. This can limit protein production, resulting in muscle breakdown.

See for yourself

L-Glutamine 750 mg by Carlson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Glutamine 750 mg by Carlson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
750 mg per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Other (inactive) ingredients: Beef Gelatin Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutamine 750 mg by Carlson Drug Interactions

Want to check YOUR meds against L-Glutamine 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Glutamine 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Glutamine 750 mg, from the product label.

Carlson

See all Carlson products
Name
Carlson Division of J.R. Carlson Laboratories, Inc.
City
Arlington Heights
State
IL
ZipCode
60004
Phone Number
888-234-5656
Web Address
www.carlsonlabs.com
Pharmacist Counseling Corner

L-Glutamine 750 mg by Carlson: Common Questions

Does L-Glutamine 750 mg by Carlson interact with any medications?
Yes. Based on its ingredients, L-Glutamine 750 mg has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Glutamine 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take L-Glutamine if I'm pregnant?
Yes—L-Glutamine is rated Likely Safe in pregnancy. If you're pregnant and considering it, a quick chat with your doctor or pharmacist can confirm it's right for your situation.
What if I'm breastfeeding?
There isn't enough safety data on glutamine during breastfeeding. Talk with your doctor or pharmacist before taking this supplement while nursing—they can weigh the benefits and risks for you.
Does L-Glutamine actually work?
It's rated Effective for sickle cell disease. For other uses—like recovery after surgery, HIV/AIDS-related wasting, or severe illness—the evidence is Possibly Effective, meaning some studies are promising but we need more research to be confident.
What side effects should I expect?
Most side effects are digestive: bloating, constipation, diarrhea, nausea, and flatulence. Headache and muscle pain have also been reported. These tend to be mild and well tolerated, especially in healthy adults.
Is this safe if I have kidney or liver disease?
The data advises caution. If you have either condition, use this supplement only under your doctor's supervision—they'll know whether it's appropriate for your situation.
Why is there a warning about anticonvulsants?
Glutamine converts to glutamate, a brain chemical that might work against seizure medications. It hasn't happened in real patients yet, but it's theoretical enough to warrant checking with your doctor or pharmacist first if you take anticonvulsants.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutamine 750 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutamine 750 mg label
Go deeper

The Full Monographs Behind L-Glutamine 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Glutamine 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring