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Dietary supplement

L-Glutamine 800 mg Ingredients & Drug Interactions

by NutriCology

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Glutamine 800 mg is a dietary supplement by NutriCology with 1 active ingredient. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Glutamine 800 mg by NutriCology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-glutamine, an amino acid your body makes naturally and uses for gut health, immune function, and muscle recovery. The capsule also holds inactive ingredients (hydroxypropyl methylcellulose, microcrystalline cellulose, and magnesium stearate) that help form and stabilize the supplement.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Brain and GI tract fuel.
  • We looked for evidence on: Critical illness (trauma), Crohn disease, Exercise-induced muscle damage, Hematopoietic stem cell transplant (HSCT), HIV/AIDS-related wasting, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Critical illness (trauma), Pancreatitis.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Crohn disease.

L-glutamine is rated effective for sickle cell disease. For HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma, the evidence is listed as possibly effective — meaning some research supports it, but more data would strengthen confidence.

The facts we hold don't describe what dose or duration was studied for these uses, so talk with your doctor about whether it fits your specific situation.

The evidence, ingredient by ingredient Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated by healthy adults. The most common side effects are gastrointestinal: belching, bloating, constipation, flatulence, diarrhea, nausea, vomiting, and GI pain.

Headache and musculoskeletal pain have also been reported. A small number of people have experienced dizziness or, in rare cases among those with bipolar disorder, mood changes (mania or hypomania).

If you have kidney or liver disease, use this only under medical supervision. Not enough safety data exists for pregnancy, so talk with your doctor before taking it if you're pregnant.

The same applies to breastfeeding — safety information is limited, so check with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glutamine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsant medications (drugs used to prevent seizures), check with your doctor or pharmacist before starting L-glutamine. Glutamine may theoretically reduce how well these drugs work, though this hasn't been confirmed in patients yet.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-glutamine is well studied for sickle cell disease and has some evidence supporting use in wasting and recovery from surgery or critical illness. If you take an anticonvulsant medication, check with your doctor or pharmacist before starting this supplement.

People with kidney or liver disease should use it only under medical supervision. Talk it over with your own healthcare provider to see if it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Glutamine 800 mg, straight from the product label.

Brand NutriCology
Barcode (UPC) 713947540507
Net contents 250 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235394
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Glutamine 800 mg by NutriCology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
125
UPC/BARCODE
713947540507
IngredientAmount% DV
L-Glutamine1.6 Gram(s)--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

L-Glutamine, a free form amino acid. High purity, well tolerated.

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 or 2 capsules one to three times daily between meals, or as directed by a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

NutriCology Innovative Nutrition

Formulation

Brain and GI Tract fuel Hypoallergenic

FDA Statement of Identity

Dietary Supplement

See for yourself

L-Glutamine 800 mg by NutriCology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Glutamine 800 mg by NutriCology

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container125 Amounts shown are per serving.

L-Glutamine

Interacts with
50 drugs
1.6 Gram(s) per serving

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...

L-Glutamine monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Glutamine 800 mg by NutriCology Drug Interactions

Want to check YOUR meds against L-Glutamine 800 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Glutamine 800 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Glutamine 800 mg, from the product label.

NutriCology

See all NutriCology products
Name
NutriCology
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.nutricology.com
Pharmacist Counseling Corner

L-Glutamine 800 mg by NutriCology: Common Questions

Does L-Glutamine 800 mg by NutriCology interact with any medications?
Yes. Based on its ingredients, L-Glutamine 800 mg has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Glutamine 800 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What side effects should I expect from L-glutamine?
Most people tolerate it well, but stomach-related side effects are common: bloating, gas, constipation, diarrhea, nausea, and stomach pain. You might also get a headache or musculoskeletal pain. Dizziness has been reported rarely, and in a few people with bipolar disorder, mood changes occurred at higher doses. If side effects bother you, your doctor can help you lower the dose or try a different approach.
Is L-glutamine safe during pregnancy?
L-glutamine is rated likely safe during pregnancy, so the data supports its use if your doctor recommends it. That said, talk with your doctor or pharmacist before taking it to make sure it's right for your individual situation.
Can I take L-glutamine while breastfeeding?
Not enough safety information exists for breastfeeding, so you shouldn't take supplement doses of it unless your doctor or lactation specialist advises otherwise. Check with them for personalized guidance.
What is L-glutamine actually used for?
It's an amino acid your body makes and uses for gut health, immune support, and muscle recovery. This product is rated effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, recovery after surgery, and critical illness from trauma.
Do I need to worry about this product if I have kidney or liver disease?
Yes — use it only under medical supervision if you have either condition. Talk with your doctor first to make sure it's appropriate for you and that you're taking the right dose.
Will L-glutamine interfere with my seizure medication?
Glutamine is broken down into glutamate, which may theoretically reduce how well anticonvulsant drugs work. This interaction hasn't been reported in actual patients yet, but it's a documented concern. Check with your doctor or pharmacist before starting this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Glutamine 800 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Glutamine 800 mg label
Go deeper

The Full Monographs Behind L-Glutamine 800 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Glutamine 800 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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