Liquid Chlorophyll 100 mg Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Liquid Chlorophyll 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Liquid Chlorophyll 100 mg is a dietary supplement by Swanson with 2 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 468 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Liquid Chlorophyll 100 mg by Swanson
Ask about any prescription or over-the-counter medication and we check it for interactions with Liquid Chlorophyll 100 mg by Swanson — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Liquid Chlorophyll 100 mg by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid supplement contains 2 active ingredients: sodium and chlorophyll. The product also includes water and glycerin as inactive ingredients that serve as the liquid base and preserve the formula.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that this product is effective for the conditions it may be marketed for. Sodium has been rated likely effective for cystic fibrosis and possibly effective for amphotericin B nephrotoxicity, but those are medical uses, not typical reasons someone buys a chlorophyll supplement.
Chlorophyll's effectiveness for wound healing, herpes, shingles, skin cancer, and pancreatitis is rated insufficient — meaning the evidence isn't solid enough to say whether it works.
How safe is it?
Well-documented data
Sodium is well tolerated at normal dietary amounts, but this product delivers additional sodium on top of what you eat. Too much sodium is linked to high blood pressure, kidney strain, and heart problems.
The safety notes advise avoiding sodium supplements or very high intake without talking to your doctor first. Chlorophyll is generally well tolerated in short-term use, but thorough safety data are limited.
The most common side effect is photosensitization — increased sensitivity to sunlight, occasionally severe enough to cause pseudoporphyria (blistering that resembles porphyria cutanea tarda). The product should not be used in pregnancy, and safety during breastfeeding is unknown — talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before using this product if you take lithium (blood levels can shift dangerously), blood pressure medications, corticosteroids, methotrexate, didanosine, sodium phosphates, tolvaptan, or any drug that contains sodium or makes your skin sensitive to sun. Sodium's effect on your medications depends on your total sodium intake from food and supplements combined.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines sodium and chlorophyll, so it's not ideal if you're watching your sodium intake or managing high blood pressure, heart disease, kidney disease, or taking lithium. If you take methotrexate or drugs that make you photosensitive, check with your doctor or pharmacist before starting.
If you're pregnant or breastfeeding, talk with your doctor or pharmacist — the safety data aren't there to support use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Liquid Chlorophyll 100 mg, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614060316 |
| Net contents | 16 Fluid Ounce(s); 473 mL |
| Market status | On market |
| Date entered into DSLD | Feb 22, 2024 |
| DSLD ID | 308647 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Liquid Chlorophyll 100 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 0 Calorie(s) | -- |
| Sodium | 5 mg | -- |
| Chlorophyll | 100 mg | -- |
Other ingredients: Water, Filtered, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Supports the body's ability to cleanse and detoxify
Cleanse and detox
Formula
Features a stabilized, water-soluble form of chlorophyll derived from alfalfa and mulberry
Liquid chlorophyll 100 mg per serving
General Statements
Science-backed quality since 1969
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, mix one tablespoon in an eight-ounce glass of distilled water three times per day. Shake well before opening.
Storage
Refrigerate unused product after opening. Good for 30 days after opening.
Store in a cool, dry place.
Precautions
Warning: for adults only.
Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking any prescription medications, especially blood-thinning medications.
Keep out of reach of children.
Do not use if seal is broken.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Liquid Chlorophyll 100 mg by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Liquid Chlorophyll 100 mg by Swanson
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size15 mL Dosage formLiquid Servings per container31 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsChlorophyll
Interacts with337 drugs
Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...
Chlorophyll monograph & interactionsOther (inactive) ingredients: Water, Filtered, Glycerin. These complete the product’s ingredient list but are not active constituents.
Liquid Chlorophyll 100 mg by Swanson Drug Interactions
HelloPharmacist Interaction Report
Swanson's Liquid Chlorophyll 100 mg contains sodium and chlorophyll, both of which interact with medications.
Sodium is the ingredient driving most of the interactions — it affects blood pressure medications, corticosteroids, lithium, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs. The most serious concern is with lithium: high sodium intake can lower lithium levels and reduce how well it works, while low sodium intake can raise lithium levels dangerously high and cause toxicity.
Read the full breakdown — every affected drug type, severity by severity
Chlorophyll adds two more interactions to watch for. It may increase the risk of photosensitization (sun sensitivity) if you're also taking photosensitizing drugs — drugs that make your skin react badly to sun exposure.
It may also slow how your body clears methotrexate, a cancer and autoimmune medication, which could allow it to build up to harmful levels.
Altogether, these interactions span 468 individual medications. Because sodium is so common in both drugs and foods, the effects of this product depend heavily on your total sodium intake from all sources.
If you take any blood pressure medication, lithium, methotrexate, or drugs that contain sodium or make you photosensitive, check your exact medications with the tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Liquid Chlorophyll 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Liquid Chlorophyll 100 mg interact with 468 drugs. Click any drug to see the details.
2 of the 2 ingredients in Liquid Chlorophyll 100 mg interact with drugs. Each result below shows which ingredient is responsible. Chlorophyll Sodium
Amiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amiloride, Hydrochlorothiazide interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amiloride, Hydrochlorothiazide interactionAminolevulinic Acid HydrochlorideAmeluz, Gleolan
How Aminolevulinic Acid Hydrochloride interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aminolevulinic Acid Hydrochloride interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine Besylate, Benazepril interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Amlodipine, Celecoxib interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Ammonium Chloride interactionAmoxapineAsendin
How Amoxapine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amoxapine interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amphotericin, Tetracycline interactionAprocitentanTryvio
How Aprocitentan interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Aprocitentan interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aripiprazole Lauroxil interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAtenololAtenix, Tenormin
How Atenolol interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Atenolol, Chlortalidone interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Atenolol, Chlorthalidone interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Atenolol, Chlorthalidone interactionAtropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, ScopolamineAtrohist Plus, Pro Tuss, Ru-tuss, Stahist
How Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Atropine, Chlorpheniramine, Hyoscyamine, Phenylephrine, Phenylpropanolamine, Scopolamine interactionAuranofinRidaura
How Auranofin interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Auranofin interactionAzatadineOptimine
How Azatadine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Azatadine interactionAzatadine, PseudoephedrineTrinalin
How Azatadine, Pseudoephedrine interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Azatadine, Pseudoephedrine interactionAzelastine Hydrochloride, Fluticasone PropionateDymista
How Azelastine Hydrochloride, Fluticasone Propionate interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumCorticosteroids Moderate
Interaction Summary
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Read the full Sodium + Azelastine Hydrochloride, Fluticasone Propionate interactionAzilsartanEdarbi
How Azilsartan interacts with Liquid Chlorophyll 100 mg — through 1 ingredient. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Liquid Chlorophyll 100 mg — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Azilsartan, Chlorthalidone interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Azilsartan, Chlorthalidone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Liquid Chlorophyll 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Chlorophyll
Methotrexate (Trexall, Others)
Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.
Photosensitizing Drugs
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Liquid Chlorophyll 100 mg, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- swanson.com
Liquid Chlorophyll 100 mg by Swanson: Common Questions
Does Liquid Chlorophyll 100 mg by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I have high blood pressure?
Will this make me more sensitive to the sun?
Is it safe to take if I'm pregnant?
What is chlorophyll for?
How much sodium is in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Liquid Chlorophyll 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Liquid Chlorophyll 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographChlorophyll
Interacts with 337 drugsChlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...
Read the full Chlorophyll monograph →Sources & How We Checked
Liquid Chlorophyll 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
- Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
- Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
- Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
- Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
- Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
- Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
- Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
- Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
- Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
- D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
- Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
- Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
- Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
- Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
- Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
- Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
- Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
- O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
- Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
- Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
- Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
- He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
- Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
- Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
- Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
- Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
- Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
- Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
- Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
- Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
- Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
- Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
- Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
- Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
- George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
- Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed
Chlorophyll 5 references
- Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
- Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
- Brooks SL, Sanders J, Seymour JF, Mellor JD. A case of delayed methotrexate clearance following administration of a complementary medication containing chlorophyll. J Oncol Pharm Pract. 2014 Jun;20(3):225-8. PubMed
- Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
- Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed
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