Megasorb CoQ-10 400 mg Ingredients & Drug Interactions
by Solgar
What is this page for?
First and foremost: checking Megasorb CoQ-10 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Megasorb CoQ-10 400 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Megasorb Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Megasorb CoQ-10 400 mg by Solgar
Ask about any prescription or over-the-counter medication and we check it for interactions with Megasorb CoQ-10 400 mg by Solgar — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Megasorb CoQ-10 400 mg by Solgar
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Megasorb Coenzyme Q10 at 400 mg per softgel. CoQ10 is a compound your body makes naturally and uses to produce energy in your cells.
The softgel also includes inactive ingredients (rice bran oil, gelatin, vegetable glycerin, soy lecithin, paprika, and titanium dioxide) that help deliver the CoQ10.
Does it work?
Moderate evidence
CoQ10 is likely effective for treating coenzyme Q10 deficiency. For other conditions, the evidence is less clear: it's possibly effective for fibromyalgia, migraine headaches, congestive heart failure (weak heart pumping), and diabetic neuropathy (nerve damage from diabetes).
The data we hold doesn't establish effectiveness beyond these uses.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when taken as directed. The most common side effects are gastrointestinal—appetite loss, diarrhea, stomach discomfort, heartburn, nausea, and vomiting—though these occur in less than 1% of people.
Headache, dizziness, and insomnia have also been reported. Dividing daily doses above 100 mg can help reduce stomach upset.
There isn't enough reliable safety data on CoQ10 during pregnancy, so it's best to avoid it unless your doctor advises otherwise. Safety while breastfeeding hasn't been well studied—talk with your doctor about whether it's right for you.
Meds to double-check
Moderate interaction found
Before taking this CoQ10, double-check with your doctor or pharmacist if you take chemotherapy drugs (especially alkylating agents like cyclophosphamide)—CoQ10 may reduce how well they work. Warfarin (Coumadin) is another critical one to confirm: CoQ10 may weaken its blood-thinning effect.
Blood pressure medications should also be reviewed, as CoQ10 may add to their effects.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you have a CoQ10 deficiency or are interested in CoQ10 for fibromyalgia, migraine, heart failure, or diabetic nerve pain, this product may be worth considering. However, if you take warfarin, certain chemotherapy drugs, or blood pressure medications, you'll want to clear it with your doctor or pharmacist first.
Pregnancy and breastfeeding require a conversation with your healthcare provider. Most people tolerate it well, though stomach upset can happen.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Megasorb CoQ-10 400 mg, straight from the product label.
| Brand | Solgar |
|---|---|
| Barcode (UPC) | 033984009547 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2018 |
| DSLD ID | 81815 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Megasorb CoQ-10 400 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Megasorb Coenzyme Q-10 | 400 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Paprika, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
CoQ-10 is a fat-soluble antioxidant. Antioxidants help fight cell-damaging free radicals in the body. CoQ-10 promotes heart and nervous system health. This formulation is offered in an oil-based softgel to promote optimal absorption and assimilation.
Since 1947
Enhanced absorption
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
2012 Solgar, Inc.
Kaneka Q10
Kaneka and KanekaQ10 are registered trademarks of the Kaneka Corporation.
General
SOLGB50637 02B
Formulation
Gluten, wheat & dairy free
Free Of: Gluten, wheat, dairy, yeast, sugar, sodium, artificial flavor, sweetener and preservatives.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement for adults, take one (1) softgel up to two times daily, preferably with meals or as directed by a healthcare practitioner.
Precautions
If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement.
Discontinue use and consult your healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
Do not use if outer bottle seal is missing or damaged.
Storage
Store at room temperature.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Megasorb CoQ-10 400 mg by Solgar label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Megasorb CoQ-10 400 mg by Solgar
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Megasorb Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Megasorb Coenzyme Q-10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin, Paprika, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
Megasorb CoQ-10 400 mg by Solgar Drug Interactions
HelloPharmacist Interaction Report
Megasorb CoQ-10 by Solgar interacts with several types of medications through its coenzyme Q10 content.
The most serious concern is with chemotherapy drugs called alkylating agents (like cyclophosphamide)—CoQ10's antioxidant effects may theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative stress these drugs rely on to kill cancer cells.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 also interacts with warfarin (Coumadin), a blood thinner (anticoagulant). Because CoQ10 is chemically similar to vitamin K, it may have blood-clotting effects that could weaken warfarin's ability to prevent clots.
Four cases of reduced warfarin effectiveness linked to CoQ10 have been reported, though the full picture remains incomplete.
Additionally, CoQ10 may add to the blood-pressure-lowering effects of antihypertensive drugs, though this is less serious. Some research shows CoQ10 can lower blood pressure on its own, while other studies conflict on this point.
Altogether, these interactions span 198 individual medications. If you take any of these drug types—especially warfarin or chemotherapy—check your exact medications with the search tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
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Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Megasorb CoQ-10 400 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Megasorb CoQ-10 400 mg interact with drugs. Each result below shows which ingredient is responsible. Megasorb Coenzyme Q-10
AltretamineHexalen
How Altretamine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Alkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Megasorb Coenzyme Q-10 + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Megasorb Coenzyme Q-10 + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Warfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Megasorb Coenzyme Q-10 + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Megasorb CoQ-10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Megasorb Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Megasorb Coenzyme Q-10 + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Megasorb CoQ-10 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Megasorb Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Megasorb CoQ-10 400 mg, from the product label.
Solgar
See all Solgar products- Name
- Solgar, Inc.
- Street Address
- 500 Willow Tree Road
- City
- Leonia
- State
- NJ
- ZipCode
- 07605
- Phone Number
- 1-877-765-4274
- Web Address
- www.solgar.com
Megasorb CoQ-10 400 mg by Solgar: Common Questions
Does Megasorb CoQ-10 400 mg by Solgar interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is coenzyme Q10 and why would I take it?
Will CoQ10 interfere with my blood pressure medication?
Can I take this if I'm on warfarin?
What side effects should I expect?
Is CoQ10 safe during pregnancy or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Megasorb CoQ-10 400 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Megasorb CoQ-10 400 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Megasorb CoQ-10 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
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