Myo-Gen Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Myo-Gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Myo-Gen is a dietary supplement by Douglas Laboratories with 4 active ingredients. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.Based on those ingredients, 282 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Glucosamine Sulfate, Potassium, Glutamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Myo-Gen by Douglas Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Myo-Gen by Douglas Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Myo-Gen by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Myo-Gen contains four active ingredients. Creatine monohydrate supports muscle strength and athletic performance, and may help with certain neurological conditions.
Glutamine is an amino acid that plays a role in immune function and may help with sickle cell disease and recovery from critical illness. Glucosamine sulfate is used primarily for osteoarthritis joint support.
Potassium is an essential mineral that helps regulate heart rhythm, muscle function, and fluid balance. The product contains no inactive ingredients listed.
Does it work?
Strong evidence
Creatine is possibly effective for muscle strength, athletic performance, and sarcopenia (age-related muscle loss), as well as for cerebral creatine deficiency syndromes. It's been rated possibly ineffective for Huntington disease and osteopenia.
Glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, recovery after surgery, and critical illness from trauma. Glucosamine is likely effective for osteoarthritis but has insufficient evidence for aging skin, back pain, cancer, or fatty liver disease.
Potassium has no effectiveness ratings in our data — it's an essential nutrient rather than a treatment for a specific condition.
How safe is it?
Well-documented data
Creatine is generally well tolerated in healthy adults but requires caution if you have kidney problems — those with kidney disease should be careful. It should be avoided during pregnancy and breastfeeding because safety hasn't been established.
The most common side effects are dehydration, diarrhea, gastrointestinal upset, muscle cramps, and water retention. Glutamine is generally well tolerated but should be used only under medical supervision if you have kidney or liver disease; it's not recommended in pregnancy without a doctor's recommendation, and the same applies to breastfeeding.
Common side effects include bloating, constipation, diarrhea, nausea, and headache. Glucosamine is generally well tolerated but should be avoided during pregnancy and breastfeeding due to insufficient safety data.
Gastrointestinal side effects (bloating, constipation, diarrhea, nausea) are most common, and rare allergic reactions including asthma exacerbation have been reported. Potassium from food is safe, but supplements can cause dangerously high blood levels, especially in people with kidney disease.
During pregnancy, dietary potassium is fine but supplements need medical guidance; the same applies to breastfeeding. High potassium can cause heart rhythm problems, low blood pressure, nausea, and vomiting.
Meds to double-check
Major interaction found
Before taking Myo-Gen, double-check with your doctor or pharmacist if you take warfarin or other blood thinners (Major concern with glucosamine). Also flag any anticonvulsants or seizure medications (Moderate with glutamine), potassium-sparing diuretics, ACE inhibitors, or ARBs (Moderate with potassium), cancer chemotherapy drugs like etoposide or doxorubicin (Moderate with glucosamine), or acetaminophen or antidiabetes medications (Minor with glucosamine).
If you have kidney disease or take any regular medication, this conversation is essential.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Myo-Gen combines muscle support and joint ingredients, but it's not for everyone — especially if you take blood thinners, seizure medications, blood pressure or heart drugs, or cancer chemotherapy. If you have kidney disease or take any regular prescriptions, check with your doctor or pharmacist before starting it.
Pregnant and breastfeeding women should talk with their healthcare provider about whether this product is appropriate.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Myo-Gen, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 745287200339 |
| Net contents | 350 g |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2012 |
| DSLD ID | 10960 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Myo-Gen by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Creatine Monohydrate | 5000 mg | -- |
| Glutamine | 1000 mg | -- |
| Glucosamine Sulfate | 1000 mg | -- |
| Potassium | 130 mg | 4% |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
FDA Statement of Identity
A Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 slightly heaping scoop (approx 7 grams) daily. Can be taken with meals. Mix with water, non-acidic juices or other beverages.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
General Statements
Myo-Gen(R) provides significant amounts of creatine, important for muscular energy production; L-glutamine, a key amino acid needed for maintenance of muscle mass; and glucosamine sulfate, a key structural component of connective tissue.
General
MYO
Brand IP Statement(s)
amni(R) original formula
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Myo-Gen by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Myo-Gen by Douglas Laboratories
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size7 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Creatine Monohydrate
No knowninteractions
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...
Creatine Monohydrate monograph & interactionsGlutamine
Interacts with50 drugs
Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle c...
Glutamine monograph & interactionsGlucosamine Sulfate
Interacts with170 drugs
Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...
Glucosamine Sulfate monograph & interactionsPotassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsMyo-Gen by Douglas Laboratories Drug Interactions
HelloPharmacist Interaction Report
Myo-Gen by Douglas Laboratories contains four active ingredients, and through its glutamine, glucosamine sulfate, and potassium content, it does interact with medications.
The most serious interaction is glucosamine sulfate with warfarin (a blood thinner), which carries a Major severity rating — glucosamine may increase warfarin's blood-thinning effects and raise your bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Glutamine poses a Moderate interaction with anticonvulsants (seizure medications), as it's metabolized to an excitatory compound that theoretically could work against these drugs, though this hasn't been reported in humans yet. Glucosamine also has Moderate interactions with topoisomerase II inhibitors (certain cancer chemotherapy drugs) — in theory it might reduce their effectiveness, but this too hasn't been seen in people.
Potassium carries Moderate interactions with three classes of blood pressure and heart medications: potassium-sparing diuretics (water pills that conserve potassium), ACE inhibitors, and angiotensin receptor blockers (ARBs). All three can raise potassium levels in your blood, and adding a supplement increases that risk further — the concern is dangerously high potassium (hyperkalemia), which can affect your heart rhythm.
Glucosamine also has a Minor interaction with acetaminophen (Tylenol), where the painkiller may slightly reduce glucosamine's effectiveness, and a Minor one with antidiabetes drugs, though current evidence suggests this is unlikely to be a real problem in practice.
Creatine showed no interactions in our data. Altogether, these interactions span 282 individual medications.
Use the medication checker on this page to look up your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Myo-Gen?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Myo-Gen interact with 282 drugs. Click any drug to see the details.
3 of the 4 ingredients in Myo-Gen interact with drugs. Each result below shows which ingredient is responsible. Glucosamine Sulfate Potassium Glutamine
WarfarinWarfarin
How Warfarin interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
Glucosamine SulfateWarfarin (coumadin) Major
Interaction Summary
Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
Read the full Glucosamine Sulfate + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
Glucosamine SulfateWarfarin (coumadin) Major
Interaction Summary
Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
Read the full Glucosamine Sulfate + Warfarin Sodium interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Acetazolamide interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Amiloride, Hydrochlorothiazide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Aminophylline, Amobarbital, Ephedrine interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Amlodipine Besylate, Benazepril interactionAmobarbitalAmytal
How Amobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Amobarbital, Secobarbital interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Aprobarbital, Butabarbital, Phenobarbital interactionAzilsartanEdarbi
How Azilsartan interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Azilsartan, Chlorthalidone interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, PhenobarbitalBellophen, Susano
How Belladonna, Phenobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Belladonna, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBenazeprilLotensin
How Benazepril interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Benazepril, Hydrochlorothiazide interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Bendroflumethiazide, Potassium interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumPotassium-sparing Diuretics Moderate
Interaction Summary
Concomitant use increases the risk of hyperkalemia.
Read the full Potassium + Bumetanide, Potassium interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Butalbital, Phenobarbital, Secobarbital interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAngiotensin Receptor Blockers (arbs) Moderate
Interaction Summary
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptoprilAcepril, Capoten
How Captopril interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Captopril, Hydrochlorothiazide interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Carbamazepine interactionCenobamateXcopri
How Cenobamate interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Cenobamate interactionCilazaprilInhibace
How Cilazapril interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
PotassiumAce Inhibitors (aceis) Moderate
Interaction Summary
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
Read the full Potassium + Cilazapril interactionClobazamFrisium, Onfi, Sympazan
How Clobazam interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Clobazam interactionClonazepamCeberclon, Klonopin, Rivotril
How Clonazepam interacts with Myo-Gen — through 1 ingredient. Tap an ingredient for the detail:
GlutamineAnticonvulsants Moderate
Interaction Summary
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Read the full Glutamine + Clonazepam interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Myo-Gen with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Glucosamine Sulfate
Warfarin (Coumadin)
Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.
Topoisomerase Ii Inhibitors
Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.
Acetaminophen (Tylenol, Others)
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.
Antidiabetes Drugs
Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Glutamine
Anticonvulsants
Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.
Brand information
Manufacturer and brand details for Myo-Gen, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Web Address
- www.douglaslabs.com
Myo-Gen by Douglas Laboratories: Common Questions
Does Myo-Gen by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take Myo-Gen if I'm pregnant or breastfeeding?
What are the most common side effects?
Can I take this if I have kidney disease?
Does glucosamine in this product really help with joint pain?
What is glutamine supposed to do in this product?
Why is there potassium in a muscle-support product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Myo-Gen is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Myo-Gen’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Creatine
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...
Read the full Creatine monograph → Herb & supplement monographGlutamine
Interacts with 50 drugsGlutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...
Read the full Glutamine monograph → Herb & supplement monographGlucosamine
Interacts with 170 drugsGlucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...
Read the full Glucosamine monograph → Herb & supplement monographPotassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph →Sources & How We Checked
Myo-Gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 167 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Creatine 86 references
- Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
- Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
- Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
- Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
- Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
- Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
- Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
- Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
- Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
- Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
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