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Dietary supplement

Organic Bacopa Monnieri Extract Paste Ingredients & Drug Interactions

by Materia Organica

Organic Bacopa Monnieri Extract Paste label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Bacopa Monnieri Extract Paste against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Bacopa Monnieri Extract Paste is a dietary supplement by Materia Organica with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, adhd symptoms.Based on those ingredients, 930 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacopa monnieri Extract Paste. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Bacopa Monnieri Extract Paste by Materia Organica

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Bacopa Monnieri Extract Paste by Materia Organica — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Bacopa Monnieri Extract Paste by Materia Organica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Bacopa monnieri extract paste. Bacopa is a plant traditionally used in Ayurvedic medicine, and modern study has focused on how it might affect brain function and mood.

There are no inactive ingredients listed for this product.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bacopa product and its label doesn't state a use — see Bacopa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for bacopa's effectiveness isn't established in the data we hold. Our monograph rates it as having insufficient reliable evidence for Alzheimer disease, cognitive function, cognitive impairment, ADHD, sexual dysfunction, and back pain.

That means the research so far hasn't shown us enough to say whether it works for these uses — it's not that we know it doesn't work, just that we don't have strong proof yet.

The evidence, ingredient by ingredient Bacopa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacopa is generally well tolerated in studies, though quality and long-term safety data are limited. The most common side effects are gastrointestinal: abdominal cramps, diarrhea, nausea, dry mouth, headache, bloating, and indigestion.

Rates of stomach or bowel problems have ranged from 12% to 30% in trials. Some people have also reported drowsiness, insomnia, vivid dreams, and headache.

There isn't enough safety information to recommend bacopa during pregnancy or while breastfeeding. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before starting this product.

Side effects, ingredient by ingredient Bacopa

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacopa.
  • The most serious interaction on file is rated Moderate.
  • For scale: 931 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check any medications you take that are broken down by your liver's cytochrome P450 enzymes — this includes many common blood thinners, blood pressure drugs, cholesterol medications, and psychiatric drugs. Also check if you take anticholinergic drugs (like those for overactive bladder), cholinergic drugs, cevimeline, or thyroid hormone.

The interaction with cevimeline is the most serious we have on record.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bacopa has a long history in traditional medicine and may interest people looking for cognitive support, but the evidence for it in our data is still being built. Because it interacts with a very large number of medications through liver enzyme effects, this one requires a careful medication check before you start.

If you take prescription drugs, especially blood thinners, blood pressure medications, or anticholinergic drugs, run them through the checker on this page first, then talk to your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Bacopa Monnieri Extract Paste, straight from the product label.

Brand Materia Organica
Net contents 3.5 Ounce(s); 100 Gram(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336984
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Bacopa Monnieri Extract Paste by Materia Organica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
100
IngredientAmount% DV
Bacopa monnieri Extract Paste500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Seals/Symbols

USDA Organic CCOF Certified Organic Star-K (Kosher)

Formulation

USDA Organic CCOF Certified Organic

Materia Organica primarily sells bulk ingredients to manufacturers and brand owners.

Certified Organic & Kosher Certified Organic & Star-K Kosher

Better bioavailability and potency Water-extracted & water-soluble

No additives, fillers, or other ingredients No petroleum solvents used in the extraction No pesticides used growing the Bacopa Vegetarian/Vegan, Non-GMO, Non-Irradiated

Vegetarian/Vegan, Non-GMO, Non-Irradiated

Certified Organic by CCOF

Product of INDIA 3rd-Party Lab Tested in USA

No other ingredients added

Formula

Star-K (Kosher)

Our water extraction process preserves the natural nutrients & beneficial qualities of Bacopa Monnieri with improved potency and bioavailability. 100% Bacopa monnieri

Certified Organic & Kosher Certified Organic & Star-K Kosher

Suggested/Recommended/Usage/Directions

Directions: Mix 500 mg into water, milk, tea, or a smoothie. For best results consult your physician.

Precautions

Not recommended for children.

Storage

Store unopened pouches in a cool area. Refrigerate in a sealed container after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Bacopa Monnieri Extract Paste by Materia Organica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Bacopa Monnieri Extract Paste label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Bacopa Monnieri Extract Paste by Materia Organica

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container100 Amounts shown are per serving.

Bacopa monnieri Extract Paste

Interacts with
930 drugs
500 mg per serving

Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for s...

Bacopa monnieri Extract Paste monograph & interactions
Interaction report

Organic Bacopa Monnieri Extract Paste by Materia Organica Drug Interactions

Want to check YOUR meds against Organic Bacopa Monnieri Extract Paste?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
930Drugs
917 Moderate 13 Minor

Ingredients driving the most interactions

Bacopa monnieri Extract Paste 930

Individual Drug Interactions

The ingredients in Organic Bacopa Monnieri Extract Paste interact with 930 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Bacopa Monnieri Extract Paste interact with drugs. Each result below shows which ingredient is responsible. Bacopa monnieri Extract Paste

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Bacopa Monnieri Extract Paste with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacopa monnieri Extract Paste8 drug types · 930 drugs

Anticholinergic Drugs

Theoretically, concurrent use might decrease the effectiveness of both agents.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels, which could counteract the effects of anticholinergic drugs. Similarly, anticholinergic drugs might counteract the cholinergic effects of bacopa.

Likelihood Possible Evidence D
Cevimeline (Evoxac)

Theoretically, bacopa might increase the effects and adverse effects of cevimeline.
In one case, a 58-year-old female taking cevimeline long-term for Sjogren syndrome experienced hyperhidrosis, malaise, nausea, and tachycardia shortly after taking a single dose of bacopa. Symptoms resolved after two days. Cevimeline is metabolized by cytochrome P450 (CYP) 2D6 and CYP3A4, and researchers theorize that bacopa may have inhibited these isoenzymes. However, it is unclear if bacopa causes clinically significant inhibition of either CYP2D6 or CYP3A4.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of bacopa with other cholinergic drugs might have additive effects.
Bacopa seems to inhibit acetylcholinesterase and might increase acetylcholine levels. Theoretically, this could result in additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP1A2 substrates.
Research on the effects of bacopa extracts on CYP1A2 enzymes is conflicting. Some in vitro evidence shows that bacopa extract can moderately and non-competitively inhibit CYP1A2, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP2C19 substrates.
In vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C19 enzymes. It is not known whether this is clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP2C9 substrates.
Research on the effect of bacopa extracts on CYP2C9 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and non-competitively inhibit CYP2C9, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, bacopa might increase the levels and adverse effects of CYP3A4 substrates.
Research on the effects of bacopa extracts on CYP3A4 enzymes is conflicting. Some in vitro evidence suggests that bacopa extract can moderately and competitively inhibit CYP3A4, while other in vitro evidence suggests that any effect is unlikely to be clinically significant.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, bacopa might have additive effects when used with thyroid hormone.
Animal research suggests that bacopa increases thyroxine (T4) levels in mice by about 40%.

Likelihood Possible Evidence D
Bacopa monnieri Extract Paste full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Bacopa Monnieri Extract Paste, from the product label.

Materia Organica

See all Materia Organica products
Name
Materia Organica
City
Quitman
State
TX
ZipCode
75783
Phone Number
800-613-6311
Web Address
www.MateriaOrganica.com
Pharmacist Counseling Corner

Organic Bacopa Monnieri Extract Paste by Materia Organica: Common Questions

Does Organic Bacopa Monnieri Extract Paste by Materia Organica interact with any medications?
Yes. Based on its ingredients, Organic Bacopa Monnieri Extract Paste has a known interaction with 930 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Bacopa Monnieri Extract Paste contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What side effects might I experience?
Most common are gastrointestinal: cramping, diarrhea, nausea, dry mouth, and bloating, reported in about 12 to 30% of people in trials. Some people have also reported drowsiness, insomnia, vivid dreams, or headache. Stop and call your pharmacist if you notice anything concerning.
Is bacopa safe to take while pregnant or breastfeeding?
There isn't enough safety data to recommend it during pregnancy or while breastfeeding. If you're in either situation, talk with your doctor or pharmacist before starting — they know your individual health picture and can advise you.
What does bacopa do?
Bacopa is a plant used traditionally to support brain function and cognition. Modern research is still building, and we don't yet have strong enough evidence in our data to say whether it works for specific uses like memory, attention, or Alzheimer disease.
Does this product have any fillers or inactive ingredients?
No inactive ingredients are listed for this product — it's the bacopa extract paste on its own.
Why do I need to check my medications?
Bacopa can slow how your liver breaks down many drugs, raising their levels and side effects. It also interacts with certain drug classes like anticholinergics and thyroid hormones. Even if you take a common medication, it could be affected, so checking with our tool is important.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Bacopa Monnieri Extract Paste is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Bacopa Monnieri Extract Paste label
Go deeper

The Full Monographs Behind Organic Bacopa Monnieri Extract Paste’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacopa

Interacts with 930 drugs

Bacopa is an Ayurvedic herb most often used for memory and thinking. Some small studies suggest it may modestly help memory when taken regularly for several weeks, but the evidence is limite...

Read the full Bacopa monograph →
Sources

Sources & How We Checked

Organic Bacopa Monnieri Extract Paste's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacopa 12 references
  1. Stough C, Lloyd J, Clarke J, et al. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Psychopharmacology 2001;156:481-4..
  2. Yadav SK, Jain AK, Tripathi SN, Gupta JP. Irritable bowel syndrome: therapeutic evaluation of indigenous drugs. Indian J Med Res 1989;90:496-503..
  3. Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
  4. Kar, A., Panda, S., and Bharti, S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. J Ethnopharmacol. 2002;81(2):281-285. PubMed
  5. Mukherjee, G. D. and Dey, C. D. Clinical trial on Brahmi. I. J.Exp.Med.Sci. 1966;10(1):5-11.
  6. Kar A, Pandit S, Mukherjee K, Bahadur S, Mukherjee PK. Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study. J Sci Food Agric 2017;97(1):333-40. doi: 10.1002/jsfa.7739. PubMed
  7. Kongkeaw C, Dilokthornsakul P, Thanarangsarit P, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. J Ethnopharmacol 2014;151(1):528-35. PubMed
  8. Ramasamy S, Kiew LV, Chung LY. Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents. Molecules 2014;19(2):2588-601. PubMed
  9. Prabhakar S, Vishnu VY, Modi M, et al. Efficacy of Bacopa monnieri (Brahmi) and donepezil in Alzheimer's disease and mild cognitive impairment: a randomized double-blind parallel phase 2b study. Ann Indian Acad Neurol 2020;23(6):767-73. PubMed
  10. Acquarulo B, Tandon P, Macica CM. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report. J Med Case Rep 2022;16(1):253. PubMed
  11. Keegan AP, Stough C, Paris D, et al. Bacopa monnieri supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderl
  12. Yaworski AM, Blyumin M, Chang T, Mammen AL, Greene M. Necrotizing myopathy with elevated anti-HMGCR antibodies following exposure to the supplement Bacopa. Muscle Nerve 2023;67(2):E1-E3.

See these in context on the Bacopa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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