Organic Bhumyamalaki Ingredients & Drug Interactions
by Herbadiet
What is this page for?
First and foremost: checking Organic Bhumyamalaki against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Bhumyamalaki is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for kidney stones, gallstones, liver support.Based on those ingredients, 1,020 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bhumyamalaki. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Bhumyamalaki by Herbadiet
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Bhumyamalaki by Herbadiet — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Bhumyamalaki by Herbadiet
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Bhumyamalaki, also known as chanca piedra. Chanca piedra is a plant traditionally used in herbal medicine.
The capsule itself is made from vegetable cellulose, an inactive ingredient.
Does it work?
Not established
The evidence we have rates chanca piedra as possibly effective for kidney stones. For other uses — anemia of chronic disease and benign prostatic hyperplasia — the evidence is insufficient to say whether it works.
Chanca piedra is rated likely ineffective for hepatitis B.
How safe is it?
Well-documented data
Chanca piedra is generally well tolerated in the short term, though comprehensive safety studies are limited. The most commonly reported side effects are abdominal pain, nausea, and vomiting.
Fatigue has also been noted in one trial. The safety data advises against use during pregnancy and while breastfeeding — there isn't enough information to know it's safe in those situations, so talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin), diuretics (water pills), lithium, norepinephrine (Levophed), blood pressure medications, or diabetes medications. The product also affects how your liver breaks down certain drugs — CYP1A2 and CYP3A4 substrates — so if you're unsure whether your medications fall into these categories, bring your prescription list to your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you're looking at chanca piedra for kidney stones, there's some evidence it might help. But this product interacts with a wide range of medications — especially blood thinners, diuretics, lithium, and several drugs your liver metabolizes — so it's essential to check your exact prescriptions before you start.
Talk it over with your doctor or pharmacist first, and avoid it if you're pregnant or breastfeeding unless you've discussed it with your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Bhumyamalaki, straight from the product label.
| Brand | Herbadiet |
|---|---|
| Barcode (UPC) | 880839560773 |
| Net contents | 60 V-Cap(s) |
| Market status | On market |
| Date entered into DSLD | Nov 19, 2021 |
| DSLD ID | 257904 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Bhumyamalaki by Herbadiet, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bhumyamalaki | 800 mg | -- |
Other ingredients: Vegetable Cellulose Shell
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Bhumyamalaki is an excellent Ayurvedic herb for the liver. Herbadiet's broad-spectrum bhumyamalaki contains the highest organic grade, sustainably cultivated organic herb, carefully selected to bring you the full potential of nature's goodness.
Formulation
Supports liver functions Cleanses gall bladder Soothes digestive tract Promotes healthy skin
Natural color variation may occur in this product
USDA Organic
100% natural Liver & digestive support
Non-GMO
Suitable for vegetarians and vegans
Free of preservatives, binders, gluten, artificial ingredients, dairy, soy, wheat, yeast
Every batch 3rd party lab tested
FDA Disclaimer Statement
These statements have not been evaluated by FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Do not use if seal under the cap is broken or missing. Dietary supplement shouldn't be used as a substitute for a varied diet
Caution: If you are pregnant, breast feeding, or taking medications, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Not for medicinal use
Storage
Store in cool, dry place
Seals/Symbols
fssai Lic. No.: 20817018000147 Vcaps Plus GMP Good Manufacturing Practice Quality Product
USDA Organic
Vegan
General Statements
1% for the planet
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions for Use: Take 2 capsules twice a day, preferably with meals or as directed by your physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Bhumyamalaki by Herbadiet label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Bhumyamalaki by Herbadiet
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Bhumyamalaki
Interacts with1,020 drugs
Chanca piedra is a tropical herb traditionally used as a 'stone breaker' for kidney and gallstones, and for liver and urinary health. Human evidence f...
Bhumyamalaki monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose Shell. These complete the product’s ingredient list but are not active constituents.
Organic Bhumyamalaki by Herbadiet Drug Interactions
HelloPharmacist Interaction Report
Herbadiet's Organic Bhumyamalaki — which contains chanca piedra — interacts with a substantial number of medications across several categories.
The most serious concern is a moderate-severity interaction with blood thinners and antiplatelet drugs (medications that prevent clots): chanca piedra may theoretically increase bleeding risk, though this effect hasn't been confirmed in humans.
Read the full breakdown — every affected drug type, severity by severity
Additionally, moderate-severity interactions are documented with diuretics (water pills), lithium, the blood pressure drug norepinephrine (Levophed), and two broad groups of medications broken down by how your liver processes them: CYP1A2 substrates and CYP3A4 substrates. For diuretics and lithium, the concern is that chanca piedra might intensify diuretic effects or raise lithium levels — though stronger evidence shows this may not happen in practice.
For norepinephrine, chanca piedra may reduce its blood pressure–raising effect. For the liver-metabolism groups, in vitro research suggests chanca piedra could speed up CYP1A2 drugs (making them less effective) and slow down CYP3A4 drugs (raising their levels), but neither has been reported in actual patients.
Minor interactions are documented with blood pressure medications and diabetes drugs. With blood pressure medicines, there's a theoretical additive lowering effect, though most people in studies didn't show this.
With diabetes medications, chanca piedra might theoretically increase low blood sugar (hypoglycemia) risk, but a small trial showed no effect on blood sugar control.
Altogether, these interactions span 1,021 individual medications. Before you start this supplement, use the medication checker on this page or discuss your current prescriptions with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Bhumyamalaki?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Bhumyamalaki interact with 1,020 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Bhumyamalaki interact with drugs. Each result below shows which ingredient is responsible. Bhumyamalaki
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Bhumyamalaki + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Bhumyamalaki + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Bhumyamalaki + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Bhumyamalaki + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Organic Bhumyamalaki — through 1 ingredient. Tap an ingredient for the detail:
BhumyamalakiCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Bhumyamalaki + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Bhumyamalaki with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bhumyamalaki
Anticoagulant/Antiplatelet Drugs
Theoretically, chanca piedra might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In vitro research suggests that methyl brevifolincarboxylate, a constituent isolated from chanca piedra, can inhibit platelet aggregation. This effect has not been reported in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, chanca piedra might reduce the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that chanca piedra extract increases CYP1A2 activity. Theoretically, chanca piedra might increase metabolism of CYP1A2 substrates and lower serum concentrations. This interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of chanca piedra might increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that chanca piedra extract inhibits CYP3A4. Theoretically, chanca piedra might increase the levels of CYP3A4 substrates. This interaction has not been reported in humans.
Diuretic Drugs
Theoretically, concomitant use of chanca piedra with diuretics might increase diuresis.
Some preliminary clinical research in adults with hypertension shows that chanca piedra has diuretic properties. However, higher quality research in adults with kidney stones shows taking chanca piedra does not increase urine volume when compared with placebo. Until more is known, use cautiously in patients taking diuretic drugs.
Lithium
Theoretically, chanca piedra might reduce excretion and increase levels of lithium.
Some preliminary clinical research in adults with hypertension shows that chanca piedra has diuretic properties. However, higher quality research in adults with kidney stones shows that taking chanca piedra does not increase urine volume when compared with placebo. Until more is known, use cautiously in patients taking lithium. The dose of lithium might need to be decreased.
Norepinephrine (Levophed)
Theoretically, chanca piedra may reduce the effects of norepinephrine.
Animal research suggests that methyl brevifolincarboxylate, a constituent isolated from chanca piedra, can reverse blood vessel contraction caused by norepinephrine.
Antidiabetes Drugs
Theoretically, concomitant use with antidiabetes drugs might affect glucose control and increase the risk of hypoglycemia.
Animal research suggests that chanca piedra can have hypoglycemic effects. However, a small clinical study in adults with diabetes shows that chanca piedra extract 25 grams orally daily for 1 week does not lower fasting or postprandial blood glucose levels.
Antihypertensive Drugs
Theoretically, concomitant use of chanca piedra with antihypertensive drugs might have additive blood pressure lowering effects.
Animal research suggests that chanca piedra can decrease blood pressure. However, this effect was not observed in most hypertensive patients treated with chanca piedra for 10 days.
Brand information
Manufacturer and brand details for Organic Bhumyamalaki, from the product label.
Herbadiet
See all Herbadiet products- Name
- Arkure Health Care
- City
- Haryana
- State
- India
- Web Address
- www.herbadiet.in
Organic Bhumyamalaki by Herbadiet: Common Questions
Does Organic Bhumyamalaki by Herbadiet interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is chanca piedra, and what is it used for?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
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The Full Monographs Behind Organic Bhumyamalaki’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Bhumyamalaki's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chanca Piedra 18 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Indian J Exp Biol 1995; 33:861-4.
- Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Phytother.Res 2001;15(3):265-267.
- Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. B. The effect of Phyllanthus amarus aqueous extract on blood glucose in non-insulin dependent diabetic patients. Phytother.Res 2001;15(7):577-580.
- Nishiura, J. L., Campos, A. H., Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. Urol.Res 2004;32(5):362-366. PubMed
- Iizuka, T., Moriyama, H., and Nagai, M. Vasorelaxant effects of methyl brevifolincarboxylate from the leaves of Phyllanthus niruri. Biol.Pharm.Bull. 2006;29(1):177-179. PubMed
- Adeneye, A. A., Amole, O. O., and Adeneye, A. K. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice. Fitoterapia 2006;77(7-8):511-514. PubMed
- Iizuka, T., Nagai, M., Taniguchi, A., Moriyama, H., and Hoshi, K. Inhibitory effects of methyl brevifolincarboxylate isolated from Phyllanthus niruri L. on platelet aggregation. Biol.Pharm.Bull. 2007;30(2):382-384. PubMed
- Amaechina, F. C. and Omogbai, E. K. Hypotensive effect of aqueous extract of the leaves of Phyllanthus amarus Schum and Thonn (Euphorbiaceae). Acta Pol.Pharm. 2007;64(6):547-552.
- Okoli, C. O., Obidike, I. C., Ezike, A. C., Akah, P. A., and Salawu, O. A. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. Pharm.Biol. 2011;49(3):248-255.
- Moshi MJ, Uiso FC Mahunnah RL et al. A study of the effect of Phyllanthus amarus extracts on blood glucose in rabbits. International Journal of Pharmacognosy 1997;35(3):167-173. DOI
- Kumar NG, Nair AN Raghunandanan VR et al. Hypoglycaemic effect of Phyllanthus niruri leaves in rabbits. Kerala Journal of Veterinary Science 1989;20(1):77-80.
- Navarro M, Coussio J Hnatyszyn O et al. Hypoglycemic Effect of an Aqueous Extract of Phyllanthus sellowianus ("sarandi blanco") in C57BL/Ks mice. Acta Farmaceutica Bonaerense 2004;23:520-523.
- Etta HE, Udoh PB Asuquo BO et al. Effect of Phyllanthus amarus on breeding efficiency of female albino rats. Global Journal of Agricultural Sciences 2007;215-217. DOI
- Etta H. Effects of Phyllanthus amarus on litter traits in albino rats. Scientific Research and Essays 2008;370-372.
- Pucci ND, Marchini GS, Mazzucchi E, et al. Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. Int Braz J Urol 2018;44(4):758-64. PubMed
- Sowjanya K, Girish C, Bammigatti C, Prasanna Lakshmi NC. Efficacy of Phyllanthus niruri on improving liver functions in patients with alcoholic hepatitis: A double-blind randomized controlled trial. Indian J Pharmacol 2021;53(6):448-456. PubMed
- Husain I, Abdulrahman B, Dale OR, et al. Interaction of Phyllanthus amarus extract and its lignans with human xenobiotic receptors, drug metabolizing enzymes and drug transporters. J Ethnopharmacol 2025;339:119142. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC