No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Perilla Ingredients & Drug Interactions

by Earthborn Elements

Perilla label
See full label image
Capsule Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Perilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Perilla is a dietary supplement by Earthborn Elements with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Perilla by Earthborn Elements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: perilla frutescens, a plant used traditionally in Asian cuisine and herbal medicine. Gelatin is included as an inactive ingredient (the capsule material).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: seasonal allergies and airway inflammation support.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, Atopic dermatitis, Food allergies.
  • The closest evidence on file: Perilla is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Perilla is rated "Insufficient Reliable Evidence To Rate" for Asthma.

The evidence we hold does not establish perilla's effectiveness for any of the conditions listed — age-related cognitive decline, hay fever, asthma, osteoporosis, cancer, or headache. All of these carry a rating of insufficient reliable evidence, meaning we don't have solid trial data yet.

If you're considering perilla for one of these reasons, your pharmacist or doctor can discuss whether the current evidence supports a trial.

The evidence, ingredient by ingredient Perilla

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Perilla is generally well tolerated when used as a food, though supplement-strength products haven't been thoroughly studied. Orally, the main concern is a rare but serious allergic reaction called anaphylaxis — some people have had this after eating perilla seeds, possibly linked to a compound called oleosin.

Topically, dermatitis has been reported. The safety data advises against taking medicinal amounts during pregnancy or while breastfeeding because there isn't enough information to know either way.

Side effects, ingredient by ingredient Perilla

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we checked. If you take any medications, run them through the checker on this page to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Perilla is generally well tolerated as a food, but supplement-strength products are not well studied. Anyone with a history of allergic reactions to seeds or plants should be cautious.

If you're pregnant, breastfeeding, or taking any medications, talk with your pharmacist or doctor before starting — especially given the rare risk of anaphylaxis in susceptible people.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Perilla, straight from the product label.

Brand Earthborn Elements
Net contents 200 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319648
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Perilla by Earthborn Elements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
200
IngredientAmount% DV
Perilla frutescens400 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily, preferably with meals. Take with at least 8 oz of liquid.

Precautions

If pregnant, nursing, or taking medications, consult your physician.

General Statements

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FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Perilla by Earthborn Elements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Perilla label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Perilla by Earthborn Elements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

Perilla frutescens

No known
interactions
400 mg per serving

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...

Perilla frutescens monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Perilla by Earthborn Elements Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Perilla. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Perilla, from the product label.

Earthborn Elements

See all Earthborn Elements products
Name
Earthborn Elements
Street Address
9450 SW Gemini Dr #49936
City
Beaverton
State
Oregon
ZipCode
97008
Web Address
Earthbornelements.com
Pharmacist Counseling Corner

Perilla by Earthborn Elements: Common Questions

Does Perilla by Earthborn Elements interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Perilla. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Perilla contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is perilla safe to take if I'm pregnant?
There isn't enough safety data to know either way. The facts advise against medicinal amounts during pregnancy. Talk with your doctor or pharmacist about whether this is right for you.
Can perilla help with hay fever or asthma?
The evidence we hold is insufficient to say whether perilla works for either condition. If you're interested in trying it for allergies or asthma, discuss it with your doctor first.
What are the side effects of perilla?
Orally, perilla is generally well tolerated, though rare anaphylaxis has been reported in people who ate perilla seeds — possibly linked to an allergen called oleosin. If applied to skin, dermatitis can occur. If you have a history of seed or plant allergies, be cautious.
What is perilla used for?
Perilla has been used traditionally in Asian cuisine and herbal medicine. This product lists it for age-related cognitive decline, hay fever, asthma, osteoporosis, cancer, and headache, though the evidence we hold does not establish it works for any of these yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Perilla is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Perilla label
Go deeper

The Full Monographs Behind Perilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Perilla

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human evidence is limited or preliminary, so it...

Read the full Perilla monograph →
Sources

Sources & How We Checked

Perilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Perilla 4 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Kanzaki, T. and Kimura, S. Occupational allergic contact dermatitis from Perilla frutescens (shiso). Contact Dermatitis 1992;26(1):55-56.
  3. Yu H, Qiu JF, Ma LJ, Hu YJ, Li P, Wan JB. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol 2017;108(Pt B):375-91. PubMed
  4. Jeong K, Lee SY, Jeon SA, et al. Clinical and immunological characterization of perilla seed allergy in children. J Investig Allergol Clin Immunol 2021. PubMed

See these in context on the Perilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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