Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Pr Ingredients & Drug Interactions

by Liquid Labs

Pr label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pr against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pr is a dietary supplement by Liquid Labs with 1 active ingredient. Its ingredients are commonly taken for muscle building, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 3b-Hydroxy-Androst-1-Ene-17-One. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pr by Liquid Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Pr by Liquid Labs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Pr by Liquid Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Liquid Labs Pr contains one active ingredient: 1-androsterone (also called 3b-hydroxy-androst-1-ene-17-one). This is a prohormone — a compound your body converts into testosterone-like hormones after you take it.

The product is delivered as a liquid and also contains inactive ingredients like peanut oil, glycerol, and sweeteners.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient 1-androsterone product and its label doesn't state a use — see 1-androsterone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for 1-androsterone's effect on athletic performance is insufficient — we don't have reliable data to rate whether it actually works for that goal. Because the safety risks are real and well-documented, the lack of solid proof of benefit is an important consideration.

The evidence, ingredient by ingredient 1-androsterone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

1-androsterone carries real health risks. The safety data advises against it.

In people who took it for just 4 weeks, researchers saw significant changes in cholesterol (LDL cholesterol up about 29 mg/dL, HDL cholesterol down about 19 mg/dL), signs of kidney stress (creatinine went up and kidney function dropped below the normal range), and liver enzyme changes. Limited safety testing has been done overall, and a full picture of how often and how severe adverse effects are hasn't been established.

Do not use this product during pregnancy or while breastfeeding. It's a hormone-altering compound, and the risks to you and your baby are unknown.

Side effects, ingredient by ingredient 1-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 1-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use testosterone or testosterone-replacement therapy. The combination carries a moderate risk of additive hormone effects, including mood disturbances and cardiovascular, kidney, or liver problems.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a prohormone with documented risks to your heart, kidneys, liver, and cholesterol — and no proven benefit for athletic performance to weigh against those risks. If you take testosterone or any hormone medication, you need to talk with your doctor or pharmacist before considering this product.

Anyone interested should discuss the real safety concerns with their healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pr, straight from the product label.

Brand Liquid Labs
Net contents 240 mL
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 209964
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pr by Liquid Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 mL
Maximum serving Sizes:
4 mL
Servings per container
60
IngredientAmount% DV
3b-Hydroxy-Androst-1-Ene-17-One125 mg--

Other ingredients: Peanut Oil, Glycerol, Ca EDTA, N&A Flavor, Sucralose, Ace K

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary supplement

Suggested/Recommended/Usage/Directions

Directions: Snap down the insert prior to using. Shake well. Dispense 4ml under the tongue. Hold the contents under your tongue for 60 seconds, then swish the contents around your mouth and swallow completely. Use 2 doses per day. Example: 4 ml upon waking and 4 ml before bed. Wait at least 10 minutes between doses when stacking with other products

Formula

Men over 21 only!

Precautions

Men over 21 only!

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pr by Liquid Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pr label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pr by Liquid Labs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

3b-Hydroxy-Androst-1-Ene-17-One

Interacts with
8 drugs
125 mg per serving

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe o...

3b-Hydroxy-Androst-1-Ene-17-One monograph & interactions

Other (inactive) ingredients: Peanut Oil, Glycerol, Ca EDTA, N&A Flavor, Sucralose, Ace K. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pr by Liquid Labs Drug Interactions

Want to check YOUR meds against Pr?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

3b-Hydroxy-Androst-1-Ene-17-One 8

Individual Drug Interactions

The ingredients in Pr interact with 8 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pr interact with drugs. Each result below shows which ingredient is responsible. 3b-Hydroxy-Androst-1-Ene-17-One

Each ingredient & the kinds of drugs it affects

For each ingredient in Pr with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

3b-Hydroxy-Androst-1-Ene-17-One1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
3b-Hydroxy-Androst-1-Ene-17-One full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pr, from the product label.

Liquid Labs

See all Liquid Labs products
Name
Liquid Labs
Pharmacist Counseling Corner

Pr by Liquid Labs: Common Questions

Does Pr by Liquid Labs interact with any medications?
Yes. Based on its ingredients, Pr has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pr contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is 1-androsterone?
It's a prohormone — a compound your body converts into testosterone-like hormones after you take it. The product's facts list it as converted to 1-testosterone and other androgens in your system.
Does it actually improve athletic performance?
We don't have reliable evidence to say whether it works for that. The data available is insufficient to rate it.
What are the most common side effects?
In people who took it for 4 weeks, the most common problems were changes in cholesterol (LDL went up, HDL went down), signs of kidney stress, and liver enzyme changes. A full picture of how often side effects happen hasn't been fully studied.
Is it safe to take while pregnant or breastfeeding?
No. The facts advise against it during pregnancy because it's a hormone-altering compound with real health risks. Avoid it while breastfeeding too, because the hormonal risks to your baby are unknown.
What's in the liquid besides the active ingredient?
The inactive ingredients are peanut oil, glycerol, calcium EDTA, natural and artificial flavor, sucralose, and acesulfame potassium. These are fillers, binders, and flavor agents.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pr label
Go deeper

The Full Monographs Behind Pr’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

1-androsterone

Interacts with 8 drugs

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...

Read the full 1-androsterone monograph →
Sources

Sources & How We Checked

Pr's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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